eprintid: 10086406 rev_number: 23 eprint_status: archive userid: 608 dir: disk0/10/08/64/06 datestamp: 2019-11-21 11:07:23 lastmod: 2021-12-06 00:47:49 status_changed: 2019-11-21 11:07:23 type: article metadata_visibility: show creators_name: Ghanouni, A creators_name: Sanderson, SC creators_name: Pashayan, N creators_name: Renzi, C creators_name: von Wagner, C creators_name: Waller, J title: Attitudes towards risk-stratified breast cancer screening among women in England: A cross-sectional survey ispublished: inpress divisions: UCL divisions: B02 divisions: C08 divisions: D10 divisions: G11 divisions: D12 divisions: G21 divisions: J96 divisions: G19 keywords: Breast neoplasms, mass screening, risk assessment, attitude, surveys and questionnaires note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: OBJECTIVES: Risk stratification may improve the benefit/harm ratio of breast screening. Research on acceptability among potential invitees is necessary to guide implementation. We assessed women’s attitudes towards and willingness to undergo risk assessment and stratified screening. METHODS: Women in England aged 40–70 received summary information about the topic, and completed face-to-face computer-assisted interviews. Questions assessed willingness to undergo multifactorial breast cancer risk assessment, more frequent breast screening (if at very high risk), or less frequent or no screening (if at very low risk), and preferences for delivery of assessment results. RESULTS: Among 933 women, 85% considered breast cancer risk assessment a good idea, and 74% were willing to have it. Among 125 women unwilling to have risk assessment, reasons commonly related to ‘worry’ (14%) and ‘preferring not to know’ (14%). Among those willing to have risk assessment (n = 689), letters/emails were generally preferred (42%) for results about very low-risk status. Face-to-face communication was most commonly preferred for results of very high-risk status (78%). General practitioners were most commonly preferred sources of assessment results (≈40%). Breast cancer specialists were often preferred for results of very high-risk status (38%). Risk-stratified breast screening was considered a good idea by 70% and 89% were willing to have more frequent screening. Fewer would accept less (51%) or no screening (37%) if at very low risk. CONCLUSIONS: Women were generally in favour of multifactorial breast cancer risk assessment and risk-stratified screening. Some were unwilling to accept less or no screening if at very low risk. date: 2019-11-08 date_type: published official_url: https://doi.org/10.1177%2F0969141319883662 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1717841 doi: 10.1177/0969141319883662 lyricists_name: Ghanouni, Alexander lyricists_name: Pashayan, Nora lyricists_name: Renzi, Cristina lyricists_name: Von Wagner, Christian lyricists_name: Waller, Josephine lyricists_id: APGHA26 lyricists_id: NPASH45 lyricists_id: CRENZ63 lyricists_id: CVONW94 lyricists_id: JWALL05 actors_name: Ghanouni, Alexander actors_id: APGHA26 actors_role: owner full_text_status: public publication: Journal of Medical Screening event_location: England citation: Ghanouni, A; Sanderson, SC; Pashayan, N; Renzi, C; von Wagner, C; Waller, J; (2019) Attitudes towards risk-stratified breast cancer screening among women in England: A cross-sectional survey. Journal of Medical Screening 10.1177/0969141319883662 <https://doi.org/10.1177/0969141319883662>. (In press). Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10086406/3/Ghanouni_Attitudes%20towards%20risk-stratified%20breast%20cancer%20screening%20among%20women%20in%20England.%20A%20cross-sectional%20survey_AAM.pdf