eprintid: 10086335
rev_number: 16
eprint_status: archive
userid: 608
dir: disk0/10/08/63/35
datestamp: 2019-11-19 14:56:33
lastmod: 2021-09-19 22:14:39
status_changed: 2019-11-19 14:56:33
type: article
metadata_visibility: show
creators_name: Van Belleghem, SM
creators_name: Rastas, P
creators_name: Papanicolaou, A
creators_name: Martin, SH
creators_name: Arias, CF
creators_name: Supple, MA
creators_name: Hanly, JJ
creators_name: Mallet, J
creators_name: Lewis, JJ
creators_name: Hines, HM
creators_name: Ruiz, M
creators_name: Salazar, C
creators_name: Linares, M
creators_name: Moreira, GRP
creators_name: Jiggins, CD
creators_name: Counterman, BA
creators_name: Owen McMillan, W
creators_name: Papa, R
title: Complex modular architecture around a simple toolkit of wing pattern genes
ispublished: pub
divisions: UCL
divisions: B02
divisions: C08
divisions: D09
divisions: F99
keywords: Comparative genomics, Evolutionary genetics, Mimicry
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: Identifying the genomic changes that control morphological variation and understanding how they generate diversity is a major goal of evolutionary biology. In Heliconius butterflies, a small number of genes control the development of diverse wing colour patterns. Here, we used full-genome sequencing of individuals across the Heliconius erato radiation and closely related species to characterize genomic variation associated with wing pattern diversity. We show that variation around colour pattern genes is highly modular, with narrow genomic intervals associated with specific differences in colour and pattern. This modular architecture explains the diversity of colour patterns and provides a flexible mechanism for rapid morphological diversification.
date: 2017-01-30
date_type: published
publisher: NATURE PUBLISHING GROUP
official_url: https://doi.org/10.1038/s41559-016-0052
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1297068
doi: 10.1038/s41559-016-0052
lyricists_name: Mallet, James
lyricists_id: JMALL47
actors_name: Allington-Smith, Dominic
actors_id: DAALL44
actors_role: owner
full_text_status: public
publication: Nature Ecology & Evolution
volume: 1
article_number: 0052
pages: 12
citation:        Van Belleghem, SM;    Rastas, P;    Papanicolaou, A;    Martin, SH;    Arias, CF;    Supple, MA;    Hanly, JJ;                                             ... Papa, R; + view all <#>        Van Belleghem, SM;  Rastas, P;  Papanicolaou, A;  Martin, SH;  Arias, CF;  Supple, MA;  Hanly, JJ;  Mallet, J;  Lewis, JJ;  Hines, HM;  Ruiz, M;  Salazar, C;  Linares, M;  Moreira, GRP;  Jiggins, CD;  Counterman, BA;  Owen McMillan, W;  Papa, R;   - view fewer <#>    (2017)    Complex modular architecture around a simple toolkit of wing pattern genes.                   Nature Ecology & Evolution , 1     , Article 0052.  10.1038/s41559-016-0052 <https://doi.org/10.1038/s41559-016-0052>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10086335/1/Mallet_nihms855386.pdf