eprintid: 10086335 rev_number: 16 eprint_status: archive userid: 608 dir: disk0/10/08/63/35 datestamp: 2019-11-19 14:56:33 lastmod: 2021-09-19 22:14:39 status_changed: 2019-11-19 14:56:33 type: article metadata_visibility: show creators_name: Van Belleghem, SM creators_name: Rastas, P creators_name: Papanicolaou, A creators_name: Martin, SH creators_name: Arias, CF creators_name: Supple, MA creators_name: Hanly, JJ creators_name: Mallet, J creators_name: Lewis, JJ creators_name: Hines, HM creators_name: Ruiz, M creators_name: Salazar, C creators_name: Linares, M creators_name: Moreira, GRP creators_name: Jiggins, CD creators_name: Counterman, BA creators_name: Owen McMillan, W creators_name: Papa, R title: Complex modular architecture around a simple toolkit of wing pattern genes ispublished: pub divisions: UCL divisions: B02 divisions: C08 divisions: D09 divisions: F99 keywords: Comparative genomics, Evolutionary genetics, Mimicry note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: Identifying the genomic changes that control morphological variation and understanding how they generate diversity is a major goal of evolutionary biology. In Heliconius butterflies, a small number of genes control the development of diverse wing colour patterns. Here, we used full-genome sequencing of individuals across the Heliconius erato radiation and closely related species to characterize genomic variation associated with wing pattern diversity. We show that variation around colour pattern genes is highly modular, with narrow genomic intervals associated with specific differences in colour and pattern. This modular architecture explains the diversity of colour patterns and provides a flexible mechanism for rapid morphological diversification. date: 2017-01-30 date_type: published publisher: NATURE PUBLISHING GROUP official_url: https://doi.org/10.1038/s41559-016-0052 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1297068 doi: 10.1038/s41559-016-0052 lyricists_name: Mallet, James lyricists_id: JMALL47 actors_name: Allington-Smith, Dominic actors_id: DAALL44 actors_role: owner full_text_status: public publication: Nature Ecology & Evolution volume: 1 article_number: 0052 pages: 12 citation: Van Belleghem, SM; Rastas, P; Papanicolaou, A; Martin, SH; Arias, CF; Supple, MA; Hanly, JJ; ... Papa, R; + view all <#> Van Belleghem, SM; Rastas, P; Papanicolaou, A; Martin, SH; Arias, CF; Supple, MA; Hanly, JJ; Mallet, J; Lewis, JJ; Hines, HM; Ruiz, M; Salazar, C; Linares, M; Moreira, GRP; Jiggins, CD; Counterman, BA; Owen McMillan, W; Papa, R; - view fewer <#> (2017) Complex modular architecture around a simple toolkit of wing pattern genes. Nature Ecology & Evolution , 1 , Article 0052. 10.1038/s41559-016-0052 <https://doi.org/10.1038/s41559-016-0052>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10086335/1/Mallet_nihms855386.pdf