TY  - INPR
N2  - BACKGROUND: Stimulating the cerebellum with transcranial magnetic stimulation is often perceived as uncomfortable. No study has systematically tested which coil design can effectively trigger a cerebellar response with the least discomfort. OBJECTIVE: To determine the relationship between perceived discomfort and effectiveness of cerebellar stimulation using different coils: MagStim (70?mm, 110?mm-coated, 110-uncoated), MagVenture and Deymed. METHODS: Using the cerebellar-brain inhibition (CBI) protocol, we conducted a CBI recruitment curve with respect to each participant's maximum tolerated-stimulus intensity (MTI) to assess how effective each coil was at activating the cerebellum. RESULTS: Only the Deymed double-cone coil elicited CBI at low intensities (-20% MTI). At the MTI, the MagStim (110?mm coated/uncoated) and Deymed coils produced reliable CBI, whereas no CBI was found with the MagVenture coil. CONCLUSION: s: The Deymed double-cone coil was most effective at cerebellar stimulation at tolerable intensities. These results can guide coil selection and stimulation parameters when designing cerebellar TMS studies.
A1  - Spampinato, D
A1  - Ibáñez, J
A1  - Spanoudakis, M
A1  - Hammond, P
A1  - Rothwell, JC
Y1  - 2019/10/12/
ID  - discovery10086007
SN  - 1876-4754
N1  - This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
JF  - Brain Stimulation
AV  - public
UR  - https://doi.org/10.1016/j.brs.2019.09.005
KW  - Cerebellar-M1
KW  -  Cerebellum
KW  -  Connectivity
KW  -  Transcranial magnetic stimulation
TI  - Cerebellar transcranial magnetic stimulation: The role of coil type from distinct manufacturers
ER  -