eprintid: 10085690
rev_number: 23
eprint_status: archive
userid: 608
dir: disk0/10/08/56/90
datestamp: 2019-11-12 11:36:58
lastmod: 2021-09-26 22:49:46
status_changed: 2019-11-12 11:36:58
type: article
metadata_visibility: show
creators_name: Ku, P-W
creators_name: Hamer, M
creators_name: Liao, Y
creators_name: Hsueh, M-C
creators_name: Chen, L-J
title: Device-measured light-intensity physical activity and mortality: A meta-analysis
ispublished: pub
divisions: UCL
divisions: B02
divisions: C10
divisions: D16
keywords: guideline, LIPA, meta-regression, recommendation, review
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: INTRODUCTION: The association of light‐intensity physical activity (LPA) with mortality is poorly understood. This meta‐analysis of cohort studies aimed to examine the dose‐response relationships between daily device‐measured LPA and mortality in adults aged 18 or older and to explore whether the associations were independent of moderate‐to‐vigorous physical activity (MVPA). METHODS: Searches for prospective cohort studies providing effect estimates of daily LPA (exposure) on all‐cause mortality (outcome) were systematically undertaken in electronic databases up to April 30, 2019. Subgroup analyses and meta‐regression analyses with random‐effects models were performed to quantify the dose‐response relationships between daily LPA and mortality. Sensitivity analyses were also conducted to assess the stability of the results. RESULTS: A total of 11 studies were included in the meta‐analysis. Analyses contained 49 239 individuals (mean age 60.7, SD = 13.6) who were followed up for a mean 6.2 years (2.3‐14.2 years), during which 3669 (7.5%) died. In comparison with the reference group (<3 h/d), the pooled HRs (and 95% CIs) of mortality were 0.71 (0.62‐0.82), 0.68 (0.59‐0.79), 0.56 (0.44‐0.71) for groups 3 to <5 h/d, 5 to <7 h/d, and more than 7 hours a day LPA, respectively. Meta‐regression models indicated that there was a log‐cubic dose‐response relationship between daily LPA and mortality in adults and older people, independent of MVPA. CONCLUSIONS: Time spent in daily LPA was associated with reduced risks of mortality in adults and older people. These data support the inclusion of LPA in the future physical activity guidelines.
date: 2020-01
date_type: published
publisher: WILEY
official_url: https://doi.org/10.1111/sms.13557
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1717941
doi: 10.1111/sms.13557
lyricists_name: Hamer, Mark
lyricists_id: MHAME21
actors_name: Hamer, Mark
actors_id: MHAME21
actors_role: owner
full_text_status: public
publication: Scandinavian Journal of Medicine & Science in Sports
volume: 30
number: 1
pagerange: 13-24
pages: 12
issn: 1600-0838
citation:        Ku, P-W;    Hamer, M;    Liao, Y;    Hsueh, M-C;    Chen, L-J;      (2020)    Device-measured light-intensity physical activity and mortality: A meta-analysis.                   Scandinavian Journal of Medicine & Science in Sports , 30  (1)   pp. 13-24.    10.1111/sms.13557 <https://doi.org/10.1111/sms.13557>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10085690/2/Hamer_Device-measured%20light-intensity%20physical%20activity%20and%20mortality_AAM.pdf