TY  - JOUR
UR  - https://doi.org/10.1093/bioinformatics/btz683
SP  - 1314
TI  - EpiGraph: an open-source platform to quantify epithelial organization
IS  - 4
N2  - SUMMARY: Here we present EpiGraph, an image analysis tool that quantifies epithelial organization. Our method combines computational geometry and graph theory to measure the degree of order of any packed tissue. EpiGraph goes beyond the traditional polygon distribution analysis, capturing other organizational traits that improve the characterization of epithelia. EpiGraph can objectively compare the rearrangements of epithelial cells during development and homeostasis to quantify how the global ensemble is affected. Importantly, it has been implemented in the open-access platform Fiji. This makes EpiGraph very user friendly, with no programming skills required.
VL  - 36
Y1  - 2020/02/15/
A1  - Vicente-Munuera, P
A1  - Gómez-Gálvez, P
A1  - Tetley, RJ
A1  - Forja, C
A1  - Tagua, A
A1  - Letrán, M
A1  - Tozluoglu, M
A1  - Mao, Y
A1  - Escudero, LM
N1  - This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
ID  - discovery10083201
AV  - public
EP  - 1316
JF  - Bioinformatics
ER  -