TY - JOUR JF - Gut N1 - This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. TI - British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults N2 - Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease. Both represent chronic inflammation of the gastrointestinal tract, which displays heterogeneity in inflammatory and symptomatic burden between patients and within individuals over time. Optimal management relies on understanding and tailoring evidence-based interventions by clinicians in partnership with patients. This guideline for management of inflammatory bowel disease in adults over 16 years of age was developed by Stakeholders representing UK physicians (British Society of Gastroenterology), surgeons (Association of Coloproctology of Great Britain and Ireland), specialist nurses (Royal College of Nursing), paediatricians (British Society of Paediatric Gastroenterology, Hepatology and Nutrition), dietitians (British Dietetic Association), radiologists (British Society of Gastrointestinal and Abdominal Radiology), general practitioners (Primary Care Society for Gastroenterology) and patients (Crohn's and Colitis UK). A systematic review of 88?247 publications and a Delphi consensus process involving 81 multidisciplinary clinicians and patients was undertaken to develop 168 evidence- and expert opinion-based recommendations for pharmacological, non-pharmacological and surgical interventions, as well as optimal service delivery in the management of both ulcerative colitis and Crohn's disease. Comprehensive up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and postoperative management, as well as structure and function of the multidisciplinary team and integration between primary and secondary care. Twenty research priorities to inform future clinical management are presented, alongside objective measurement of priority importance, determined by 2379 electronic survey responses from individuals living with ulcerative colitis and Crohn's disease, including patients, their families and friends. UR - https://doi.org/10.1136/gutjnl-2019-318484 Y1 - 2019/09/27/ EP - s106 SN - 1468-3288 KW - 5-ASA KW - 5-aminosalicylate KW - CMV KW - Crohn?s disease KW - CD KW - JAK KW - Ulcerative colitis KW - UC KW - adalimumab KW - adherence KW - adolescent KW - adult KW - anaemia KW - anti-TNF KW - anti-drug antibodies KW - antibiotic KW - antibiotics KW - azathioprine KW - biomarker KW - breastfeeding KW - budesonide KW - calprotectin KW - cancer KW - care KW - chemoprevention KW - ciclosporin KW - classification KW - clostridium difficile KW - cognitive behavioural therapy KW - CBT KW - colectomy KW - colitis KW - colonoscopy KW - computerised tomography KW - CT KW - corticosteroid KW - cyclosporine KW - cytomegalovirus KW - diagnosis KW - diet KW - endoscopic KW - endoscopy KW - enema KW - faecal microbial transplant KW - fatigue KW - fetus KW - fistula KW - granuloma KW - guideline KW - hydrocortisone KW - ileitis KW - inflammatory bowel disease KW - IBD KW - infliximab KW - integrin KW - janus kinase inhibator KW - magnetic resonance KW - MR KW - management KW - mercaptopurine KW - mesalazine KW - methylprednisolone KW - monitoring KW - multidisciplinary team KW - MDT KW - nutrition KW - perianal KW - pouch KW - pouchitis KW - prednisolone KW - pregnancy KW - primary stress KW - probiotic KW - psychology KW - psychotherapy KW - self-management KW - shared care KW - sigmoidoscopy KW - smoking KW - stress KW - stricture KW - suppository KW - surgery KW - surveillance KW - telephone clinic KW - therapeutic drug monitoring KW - therapy KW - thiopurine KW - tofacitinib KW - tuberculosis KW - TB KW - ultrasound KW - ustekinumab KW - vaccination KW - vaccine KW - vedolizumab KW - virtual clinic KW - vitamin D A1 - Lamb, CA A1 - Kennedy, NA A1 - Raine, T A1 - Hendy, PA A1 - Smith, PJ A1 - Limdi, JK A1 - Hayee, B A1 - Lomer, MCE A1 - Parkes, GC A1 - Selinger, C A1 - Barrett, KJ A1 - Davies, RJ A1 - Bennett, C A1 - Gittens, S A1 - Dunlop, MG A1 - Faiz, O A1 - Fraser, A A1 - Garrick, V A1 - Johnston, PD A1 - Parkes, M A1 - Sanderson, J A1 - Terry, H A1 - IBD guidelines eDelphi consensus group A1 - Gaya, DR A1 - Iqbal, TH A1 - Taylor, SA A1 - Smith, M A1 - Brookes, M A1 - Hansen, R A1 - Hawthorne, AB SP - s1 AV - public ID - discovery10083052 VL - 68 ER -