eprintid: 10082480 rev_number: 23 eprint_status: archive userid: 608 dir: disk0/10/08/24/80 datestamp: 2019-09-27 17:30:29 lastmod: 2021-12-01 23:58:01 status_changed: 2019-09-27 17:30:29 type: article metadata_visibility: show creators_name: Marwick, TH creators_name: Amann, K creators_name: Bangalore, S creators_name: Cavalcante, JL creators_name: Charytan, DM creators_name: Craig, JC creators_name: Gill, JS creators_name: Hlatky, MA creators_name: Jardine, AG creators_name: Landmesser, U creators_name: Newby, LK creators_name: Herzog, CA creators_name: Cheung, M creators_name: Wheeler, DC creators_name: Winkelmayer, WC creators_name: Sarnak, MJ creators_name: Banerjee, D creators_name: Briguori, C creators_name: Chang, TI creators_name: Chen, CL creators_name: deFilippi, CR creators_name: Ding, X creators_name: Ferro, CJ creators_name: Gill, J creators_name: Gössl, M creators_name: Isbel, NM creators_name: Ishii, H creators_name: Jardine, MJ creators_name: Kalra, PA creators_name: Laufer, G creators_name: Lentine, KL creators_name: Lobdell, KW creators_name: Lok, CE creators_name: London, GM creators_name: Małyszko, J creators_name: Mark, PB creators_name: Marwan, M creators_name: Nie, Y creators_name: Parfrey, PS creators_name: Pecoits-Filho, R creators_name: Pilmore, H creators_name: Qunibi, WY creators_name: Raggi, P creators_name: Rattazzi, M creators_name: Rossignol, P creators_name: Ruturi, J creators_name: Sabanayagam, C creators_name: Shanahan, CM creators_name: Shroff, GR creators_name: Shroff, R creators_name: Webster, AC creators_name: Weiner, DE creators_name: Winther, S creators_name: Wiseman, AC creators_name: Yip, A creators_name: Zarbock, A title: Chronic kidney disease and valvular heart disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference ispublished: pub divisions: UCL divisions: B02 divisions: C10 divisions: D17 divisions: G93 divisions: D13 keywords: aortic stenosis, chronic kidney disease, end-stage kidney disease, mitral annular calcification, valvular heart disease note: Copyright © 2019 The Authors. Published by Elsevier Inc. on behalf of the International Society of Nephrology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/ 4.0/). abstract: Chronic kidney disease (CKD) is a major risk factor for valvular heart disease (VHD). Mitral annular and aortic valve calcifications are highly prevalent in CKD patients and commonly lead to valvular stenosis and regurgitation, as well as complications including conduction system abnormalities and endocarditis. VHD, especially mitral regurgitation and aortic stenosis, is associated with significantly reduced survival among CKD patients. Knowledge related to VHD in the general population is not always applicable to CKD patients because the pathophysiology may be different, and CKD patients have a high prevalence of comorbid conditions and elevated risk for periprocedural complications and mortality. This Kidney Disease: Improving Global Outcomes (KDIGO) review of CKD and VHD seeks to improve understanding of the epidemiology, pathophysiology, diagnosis, and treatment of VHD in CKD by summarizing knowledge gaps, areas of controversy, and priorities for research. date: 2019-10 date_type: published official_url: https://doi.org/10.1016/j.kint.2019.06.025 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1697239 doi: 10.1016/j.kint.2019.06.025 lyricists_name: Shroff, Rukshana lyricists_name: Wheeler, David lyricists_id: RCSHR02 lyricists_id: DWHEE12 actors_name: Bracey, Alan actors_id: ABBRA90 actors_role: owner full_text_status: public publication: Kidney International volume: 96 number: 4 pagerange: 836-849 issn: 1523-1755 citation: Marwick, TH; Amann, K; Bangalore, S; Cavalcante, JL; Charytan, DM; Craig, JC; Gill, JS; ... Zarbock, A; + view all <#> Marwick, TH; Amann, K; Bangalore, S; Cavalcante, JL; Charytan, DM; Craig, JC; Gill, JS; Hlatky, MA; Jardine, AG; Landmesser, U; Newby, LK; Herzog, CA; Cheung, M; Wheeler, DC; Winkelmayer, WC; Sarnak, MJ; Banerjee, D; Briguori, C; Chang, TI; Chen, CL; deFilippi, CR; Ding, X; Ferro, CJ; Gill, J; Gössl, M; Isbel, NM; Ishii, H; Jardine, MJ; Kalra, PA; Laufer, G; Lentine, KL; Lobdell, KW; Lok, CE; London, GM; Małyszko, J; Mark, PB; Marwan, M; Nie, Y; Parfrey, PS; Pecoits-Filho, R; Pilmore, H; Qunibi, WY; Raggi, P; Rattazzi, M; Rossignol, P; Ruturi, J; Sabanayagam, C; Shanahan, CM; Shroff, GR; Shroff, R; Webster, AC; Weiner, DE; Winther, S; Wiseman, AC; Yip, A; Zarbock, A; - view fewer <#> (2019) Chronic kidney disease and valvular heart disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International , 96 (4) pp. 836-849. 10.1016/j.kint.2019.06.025 <https://doi.org/10.1016/j.kint.2019.06.025>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10082480/1/1-s2.0-S0085253819307847-main.pdf