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<https://discovery.ucl.ac.uk/id/eprint/10079834> <http://purl.org/ontology/bibo/abstract> "The design and analysis of active-control trials to evaluate experimental HIV pre-exposure prophylaxis (PrEP)\r\nagents pose serious statistical challenges. We recently proposed a new outcome measure, the averted infections\r\nratio (AIR) – the proportion of infections that would be averted by using the experimental agent rather than the\r\ncontrol agent (compared to no intervention). The main aim of the current paper is to examine the mathematical\r\nconnection between AIR and the HIV incidence rate ratio, the standard outcome measure. We also consider\r\nthe sample size implications of the choice of primary outcome measure and explore the connection between\r\neffectiveness and efficacy under a simplified model of adherence."^^<http://www.w3.org/2001/XMLSchema#string> .
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