eprintid: 10078515
rev_number: 22
eprint_status: archive
userid: 608
dir: disk0/10/07/85/15
datestamp: 2019-07-23 11:45:01
lastmod: 2021-12-13 23:59:18
status_changed: 2019-07-23 11:45:01
type: article
metadata_visibility: show
creators_name: Bone, JK
creators_name: Lewis, G
creators_name: Button, KS
creators_name: Duffy, L
creators_name: Harmer, CJ
creators_name: Munafò, MR
creators_name: Penton-Voak, IS
creators_name: Wiles, NJ
creators_name: Lewis, G
title: Variation in recognition of happy and sad facial expressions and self-reported depressive symptom severity: A prospective cohort study
ispublished: inpress
divisions: UCL
divisions: B02
divisions: C07
divisions: D79
divisions: D12
divisions: J96
keywords: Depression, Facial expressions, Emotion recognition, Cognition, Cohort study
note: This is an open access article under the CC BY-NC-ND license
(http://creativecommons.org/licenses/by-nc-nd/4.0/).
abstract: Objective: Cognitive theories suggest people with depression interpret self-referential social information negatively. However, it is unclear whether these biases precede or follow depression. We investigated whether facial
expression recognition was associated with depressive symptoms cross-sectionally and longitudinally.
Methods: Prospective cohort study of people who had visited UK primary care in the past year reporting depressive symptoms (n = 509). Depressive symptoms were measured using the Patient Health Questionnaire
(PHQ-9) at four time-points, 2 weeks apart. A computerised task assessed happy and sad facial expression recognition at three time-points (n = 505 at time 1). The unbiased hit rate measured ability to recognise emotions
accounting for any general tendency to identify the emotion when it was not present.
Results: The sample included the full range of depressive symptom severity, with 45% meeting diagnostic criteria for depression. There was no evidence that happy or sad unbiased hit rates were associated with concurrent
or subsequent depressive symptoms. There was weak evidence that, for every additional face incorrectly classified as happy, concurrent PHQ-9 scores reduced by 0.05 of a point (95% CI = -0.10 to 0.002, p = 0.06 after
adjustment for confounders). This association was strongest for more ambiguous facial expressions (interaction
term p<0.001).
Limitations: This was an observational study with relatively short follow-up (6 weeks) and small changes in
depressive symptoms and emotion recognition. Only 7% of invited patients consented to participate.
Conclusions: Reduced misclassifications of ambiguous faces as happy could be a state marker of depression, but
was not associated with subsequent depressive symptoms. Future research should focus on the interpretation of
ambiguous social information
date: 2019-10-01
date_type: published
official_url: https://doi.org/10.1016/j.jad.2019.06.025
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1674150
doi: 10.1016/j.jad.2019.06.025
lyricists_name: Bone, Jessica
lyricists_name: Duffy, Larisa
lyricists_name: Lewis, Gemma
lyricists_name: Lewis, Glyn
lyricists_id: JKBON37
lyricists_id: LDUFF35
lyricists_id: GLEWI99
lyricists_id: GHLEW69
actors_name: Duffy, Larisa
actors_id: LDUFF35
actors_role: owner
full_text_status: public
publication: Journal of Affective Disorders
volume: 257
pagerange: 461-469
issn: 1573-2517
citation:        Bone, JK;    Lewis, G;    Button, KS;    Duffy, L;    Harmer, CJ;    Munafò, MR;    Penton-Voak, IS;         ... Lewis, G; + view all <#>        Bone, JK;  Lewis, G;  Button, KS;  Duffy, L;  Harmer, CJ;  Munafò, MR;  Penton-Voak, IS;  Wiles, NJ;  Lewis, G;   - view fewer <#>    (2019)    Variation in recognition of happy and sad facial expressions and self-reported depressive symptom severity: A prospective cohort study.                   Journal of Affective Disorders , 257    pp. 461-469.    10.1016/j.jad.2019.06.025 <https://doi.org/10.1016/j.jad.2019.06.025>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10078515/1/Bone%20et%20al.pdf