?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Abundance+of+cell+bodies+can+explain+the+stick+model%E2%80%99s+failure+in+grey+matter+at+high+bvalue&rft.creator=Palombo%2C+M&rft.creator=Shemesh%2C+N&rft.creator=Ianus%2C+A&rft.creator=Alexander%2C+D&rft.creator=Zhang%2C+H&rft.description=This+work+investigates+the+validity+of+the+stick+model+used+in+diffusion-weighted+MRI+for+modelling+cellular+projections+in+brain+tissue.+We+hypothesize+that+the+model+will+fail+to+describe+the+signals+from+grey+matter+due+to+an+abundance+of+cell+bodies.+Using+high+b-value+(%E2%89%A53+ms%2F%C2%B5m+)+data+from+rat+and+human+brain%2C+we+show+that+the+assumption+fails+for+grey+matter.+Using+diffusion+simulation+in+realistic+digital+models+of+neurons%2Fglia%2C+we+demonstrate+the+breakdown+of+the+assumption+can+be+explained+by+the+presence+of+cell+bodies.+Our+findings+suggest+that+high+b-value+data+may+be+used+to+probe+cell+bodies.&rft.publisher=ISMRM+(International+Society+for+Magnetic+Resonance+in+Medicine)&rft.contributor=Miller%2C+KL&rft.contributor=Port%2C+JD&rft.date=2018-06-16&rft.type=Proceedings+paper&rft.publisher=Joint+Annual+Meeting+ISMRM-ESMRMB+2018&rft.language=eng&rft.source=+++++In%3A+Miller%2C+KL+and+Port%2C+JD%2C+(eds.)+Proceedings+of+the+Joint+Annual+Meeting+ISMRM-ESMRMB+2018.++++ISMRM+(International+Society+for+Magnetic+Resonance+in+Medicine)%3A+Concord%2C+CA%2C+USA.+(2018)+++++&rft.format=text&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F10074387%2F1%2FPalombo_AAM_Abstract%252001_SUBMITTED.pdf&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F10074387%2F&rft.rights=open