eprintid: 10072425 rev_number: 26 eprint_status: archive userid: 608 dir: disk0/10/07/24/25 datestamp: 2019-04-24 09:38:32 lastmod: 2021-09-26 23:09:57 status_changed: 2019-04-24 09:38:32 type: article metadata_visibility: show creators_name: de Lacy, FB creators_name: Keller, DS creators_name: Martin-Perez, B creators_name: Emile, SH creators_name: Chand, M creators_name: Spinelli, A creators_name: Lacy, AM title: The current state of the transanal approach to the ileal pouch-anal anastomosis ispublished: pub divisions: UCL divisions: B02 divisions: C10 divisions: D16 divisions: G88 keywords: Familial adenomatous polyposis, Ileal pouch-anal anastomosis, Inflammatory bowel disease, Restorative proctocolectomy, Transanal proctectomy, Transanal total mesorectal excision, Ulcerative colitis note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: BACKGROUND: The transanal approach to pelvic dissection has gained considerable traction and utilization continues to expand, fueled by the transanal total mesorectal excision (TaTME) for rectal cancer. The same principles and benefits of transanal pelvic dissection may apply to the transanal restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA)-the TaPouch procedure. Our goal was to review the literature to date on the development and current state of the TaPouch. MATERIALS AND METHODS: We performed a PubMed database search for original articles on transanal pelvic dissections, IPAA, and the TaPouch procedure, with a manual search from relevant citations in the reference list. The main outcomes were the technical aspects of the TaPouch, clinical and functional outcomes, and potential advantages, drawbacks, and future direction for the procedure. RESULTS: The conduct of the procedure has been defined, with the safety and feasibility demonstrated in small series. The reported rates of conversion and anastomotic leakage are low. There are no randomized trials or large-scale comparative studies available for comparative effectiveness compared to the traditional IPAA. CONCLUSIONS: The transanal approach to ileal pouch-anal anastomosis is an exciting adaption of the transanal total mesorectal excision for refining the technical steps of a complex operation. Additional experience is needed for comparative outcomes and defining the ideal training and implementation pathways. date: 2019-05 date_type: published official_url: https://doi.org/10.1007/s00464-019-06674-5 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1625695 doi: 10.1007/s00464-019-06674-5 pii: 10.1007/s00464-019-06674-5 lyricists_name: Chand, Manish lyricists_id: MKCHA65 actors_name: Stacey, Thomas actors_id: TSSTA20 actors_role: owner full_text_status: public publication: Surgical Endoscopy volume: 33 number: 5 pagerange: 1368-1375 event_location: Germany issn: 0930-2794 citation: de Lacy, FB; Keller, DS; Martin-Perez, B; Emile, SH; Chand, M; Spinelli, A; Lacy, AM; (2019) The current state of the transanal approach to the ileal pouch-anal anastomosis. Surgical Endoscopy , 33 (5) pp. 1368-1375. 10.1007/s00464-019-06674-5 <https://doi.org/10.1007/s00464-019-06674-5>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10072425/3/Chand%20TRANSANAL_POUCH_Manuscript_review.pdf