eprintid: 10067947 rev_number: 21 eprint_status: archive userid: 608 dir: disk0/10/06/79/47 datestamp: 2019-02-19 12:37:47 lastmod: 2021-10-06 22:47:58 status_changed: 2019-02-19 12:37:47 type: proceedings_section metadata_visibility: show creators_name: Ossowski, P creators_name: Curatolo, A creators_name: Sampson, DD creators_name: Munro, PRT title: Accurate Representation of Microscopic Scatterers in Realistic Simulation of OCT Image Formation ispublished: pub divisions: UCL divisions: B04 divisions: C05 divisions: F42 keywords: Refractive index , Biological system modeling , Scattering , Computational modeling , Optical coherence tomography , Optimized production technology , Mathematical model note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: There is currently much interest in developing OCT image formation models based on Maxwell's equations. However, all such models face a common challenge: how can microscopic scatterers be represented without limiting the overall size of the sample that can be modelled? Here we show how micro-scopic scatterers can be accurately represented on computational grids with cells too large to faithfully represent such scatterers using conventional approaches. We also validate this approach experimentally. This approach to OCT image simulation allows for image formation for biological tissues to be simulated with unprecedented realism. date: 2018-11 date_type: published publisher: IEEE official_url: https://doi.org/10.1109/IPCon.2018.8527134 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1617626 doi: 10.1109/IPCon.2018.8527134 isbn_13: 9781538653586 lyricists_name: Munro, Peter lyricists_id: PRTMU72 actors_name: Novi, Maya actors_id: MNOVI52 actors_role: owner full_text_status: public publication: 31st Annual Conference of the IEEE Photonics Society, IPC 2018 event_title: 2018 IEEE Photonics Conference (IPC), 30 September - 4 October 2018, Reston, VA, USA book_title: 2018 IEEE Photonics Conference (IPC) citation: Ossowski, P; Curatolo, A; Sampson, DD; Munro, PRT; (2018) Accurate Representation of Microscopic Scatterers in Realistic Simulation of OCT Image Formation. In: 2018 IEEE Photonics Conference (IPC). IEEE Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10067947/7/Ossowski_ieee_phot_munro_01.pdf