%0 Journal Article
%@ 2352-8737
%A Lutz, A
%A Klimecki, OM
%A Collette, F
%A Poisnel, G
%A Arenaza-Urquijo, E
%A Marchant, NL
%A De La Sayette, V
%A Rauchs, G
%A Salmon, E
%A Vuilleumier, P
%A Frison, E
%A Vivien, D
%A Chételat, G
%D 2018
%F discovery:10065791
%J Alzheimer's and Dementia: Translational Research and Clinical Interventions
%K Aging, Alzheimer's disease, Dementia, Prevention, Cognition, Reserve, Meditation expertise, Mindfulness meditation, Compassion and loving-kindness meditation, Emotion, Lifestyle, Neuroimaging, Blood markers, Sleep
%P 756-764
%T The Age-Well observational study on expert meditators in the Medit-Ageing European project
%U https://discovery.ucl.ac.uk/id/eprint/10065791/
%V 4
%X Introduction:  The Age-Well observational, cross-sectional study investigates the affective and cognitive mechanisms of meditation expertise with behavioral, neuroimaging, sleep, and biological measures sensitive to aging and Alzheimer's disease (AD).    Methods:  Thirty cognitively unimpaired individuals aged 65 years or older with at least 10,000 hours of practice in mindfulness meditation (MM) and loving-kindness and compassion meditation (LKCM) are selected. The outcomes are the neuroimaging brain correlates of MM and LKCM and the assessments of long-term meditation practices on behavioral, neural, and biological measures as compared to nonmeditator older controls from the Age-Well randomized controlled trial.    Results  Recruitment and data collection began in late 2016 and will be completed by late 2019.    Discussion:   Results are expected to foster the understanding of the effects of meditation expertise on aging and of the mechanisms of action underlying the meditation intervention in the Age-Well randomized controlled trial. These finding will contribute to the design of meditation-based prevention randomized controlled trials for the aged population and to the exploration of the possible long-time developmental trajectory of meditation training.
%Z Copyright © 2018 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer’s Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).