<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> . <> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10065198> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/title> "Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/abstract> "BACKGROUND: Patients with suspected colorectal cancer (CRC) usually undergo colonoscopy. Flexible sigmoidoscopy (FS) may be preferred if proximal cancer risk is low. We investigated which patients could undergo FS alone. METHODS: Cohort study of 7375 patients (≥55 years) referred with suspected CRC to 21 English hospitals (2004-2007), followed using hospital records and cancer registries. We calculated yields and number of needed whole-colon examinations (NNE) to diagnose one cancer by symptoms/signs and subsite. We considered narrow (haemoglobin <11 g/dL men; <10 g/dL women) and broad (<13 g/dL men; <12 g/dL women) anaemia definitions and iron-deficiency anaemia (IDA). RESULTS: One hundred and twenty-seven proximal and 429 distal CRCs were diagnosed. A broad anaemia definition identified 80% of proximal cancers; a narrow definition with IDA identified 39%. In patients with broad definition anaemia and/or abdominal mass, proximal cancer yield and NNE were 4.8% (97/2022) and 21. In patients without broad definition anaemia and/or abdominal mass, with rectal bleeding or increased stool frequency (41% of cohort), proximal cancer yield and NNE were 0.4% (13/3031) and 234. CONCLUSION: Most proximal cancers are accompanied by broad definition anaemia. In patients without broad definition anaemia and/or abdominal mass, with rectal bleeding or increased stool frequency, proximal cancer is rare and FS should suffice."^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/date> "2019" . <https://discovery.ucl.ac.uk/id/document/812727> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/publication/ext-15321827> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> . <https://discovery.ucl.ac.uk/id/publication/ext-15321827> <http://xmlns.com/foaf/0.1/name> "British Journal of Cancer"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-15321827> . <https://discovery.ucl.ac.uk/id/publication/ext-15321827> <http://www.w3.org/2002/07/owl#sameAs> <urn:issn:15321827> . <https://discovery.ucl.ac.uk/id/publication/ext-15321827> <http://purl.org/ontology/bibo/issn> "15321827" . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/forthcoming> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-edf2b1ea3f0c9496f2479afe16d74e54> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-edf2b1ea3f0c9496f2479afe16d74e54> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f2a226394589f914a65393574a2388a4> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-f2a226394589f914a65393574a2388a4> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-564b538af96d82afa2a8be3fccde1f43> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-564b538af96d82afa2a8be3fccde1f43> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ca83cea4f6a37f05a044c3b420aa1226> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-ca83cea4f6a37f05a044c3b420aa1226> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-5dca7fbd6081925f9917944dbb1b703e> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-5dca7fbd6081925f9917944dbb1b703e> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d02b7798ff4006a4c6d6367d288ec8f9> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-d02b7798ff4006a4c6d6367d288ec8f9> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-241ee6505fc85ad30d46adb72343414c> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-241ee6505fc85ad30d46adb72343414c> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ec587a1a6b50f7d531f9f3827de3360b> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-ec587a1a6b50f7d531f9f3827de3360b> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-8366c456e18efebee6798c5b210cb04a> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-8366c456e18efebee6798c5b210cb04a> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-71e103622aa88eec9cdabedc0d4323ca> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-71e103622aa88eec9cdabedc0d4323ca> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-1430770eeb73ce1cf902114ac0af9399> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-1430770eeb73ce1cf902114ac0af9399> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-bdeb070e14a4cc39d4868405bab39c0d> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-bdeb070e14a4cc39d4868405bab39c0d> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-738563374abe0526cb1a9ac42dc22225> . <https://discovery.ucl.ac.uk/id/eprint/10065198> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> . <https://discovery.ucl.ac.uk/id/eprint/10065198#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-738563374abe0526cb1a9ac42dc22225> . <https://discovery.ucl.ac.uk/id/person/ext-edf2b1ea3f0c9496f2479afe16d74e54> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-edf2b1ea3f0c9496f2479afe16d74e54> <http://xmlns.com/foaf/0.1/givenName> "AJ"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-edf2b1ea3f0c9496f2479afe16d74e54> <http://xmlns.com/foaf/0.1/familyName> "Cross"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-edf2b1ea3f0c9496f2479afe16d74e54> <http://xmlns.com/foaf/0.1/name> "AJ Cross"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-564b538af96d82afa2a8be3fccde1f43> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-564b538af96d82afa2a8be3fccde1f43> <http://xmlns.com/foaf/0.1/givenName> "EC"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-564b538af96d82afa2a8be3fccde1f43> <http://xmlns.com/foaf/0.1/familyName> "Robbins"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-564b538af96d82afa2a8be3fccde1f43> <http://xmlns.com/foaf/0.1/name> "EC Robbins"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ca83cea4f6a37f05a044c3b420aa1226> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-ca83cea4f6a37f05a044c3b420aa1226> <http://xmlns.com/foaf/0.1/givenName> "K"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ca83cea4f6a37f05a044c3b420aa1226> <http://xmlns.com/foaf/0.1/familyName> "Pack"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ca83cea4f6a37f05a044c3b420aa1226> <http://xmlns.com/foaf/0.1/name> "K Pack"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8366c456e18efebee6798c5b210cb04a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-8366c456e18efebee6798c5b210cb04a> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8366c456e18efebee6798c5b210cb04a> <http://xmlns.com/foaf/0.1/familyName> "Halligan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8366c456e18efebee6798c5b210cb04a> <http://xmlns.com/foaf/0.1/name> "S Halligan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ec587a1a6b50f7d531f9f3827de3360b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-ec587a1a6b50f7d531f9f3827de3360b> <http://xmlns.com/foaf/0.1/givenName> "KG"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ec587a1a6b50f7d531f9f3827de3360b> <http://xmlns.com/foaf/0.1/familyName> "Flashman"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ec587a1a6b50f7d531f9f3827de3360b> <http://xmlns.com/foaf/0.1/name> "KG Flashman"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-71e103622aa88eec9cdabedc0d4323ca> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-71e103622aa88eec9cdabedc0d4323ca> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-71e103622aa88eec9cdabedc0d4323ca> <http://xmlns.com/foaf/0.1/familyName> "Thomas-Gibson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-71e103622aa88eec9cdabedc0d4323ca> <http://xmlns.com/foaf/0.1/name> "S Thomas-Gibson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-1430770eeb73ce1cf902114ac0af9399> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-1430770eeb73ce1cf902114ac0af9399> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-1430770eeb73ce1cf902114ac0af9399> <http://xmlns.com/foaf/0.1/familyName> "Vance"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-1430770eeb73ce1cf902114ac0af9399> <http://xmlns.com/foaf/0.1/name> "M Vance"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-738563374abe0526cb1a9ac42dc22225> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-738563374abe0526cb1a9ac42dc22225> <http://xmlns.com/foaf/0.1/givenName> "W"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-738563374abe0526cb1a9ac42dc22225> <http://xmlns.com/foaf/0.1/familyName> "Atkin"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-738563374abe0526cb1a9ac42dc22225> <http://xmlns.com/foaf/0.1/name> "W Atkin"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5dca7fbd6081925f9917944dbb1b703e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-5dca7fbd6081925f9917944dbb1b703e> <http://xmlns.com/foaf/0.1/givenName> "JP"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5dca7fbd6081925f9917944dbb1b703e> <http://xmlns.com/foaf/0.1/familyName> "Brown"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5dca7fbd6081925f9917944dbb1b703e> <http://xmlns.com/foaf/0.1/name> "JP Brown"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-f2a226394589f914a65393574a2388a4> 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