@article{discovery10063559,
         journal = {Proceedings of Biosensing and Nanomedicine XI},
            year = {2018},
           title = {3D printed micro-scale fiber optic probe for intravascular pressure sensing},
            note = {This version is the version of the record. For information on re-use, please refer to the publisher's terms and conditions.},
          volume = {10728},
           month = {September},
             url = {https://doi.org/10.1117/12.2321980},
            issn = {0277-786X},
          author = {Poduval, R and Coote, J and Mosse, C and Finlay, M and Papakonstantinou, I and Desjardins, A},
        abstract = {Small form-factor invasive pressure sensors are widely used in minimally invasive surgery, for example to guide decision making in coronary stenting procedures. Current fiber-optic sensors can have high manufacturing complexities and costs, which severely constrains their adoption outside of niche fields. A particular challenge is the ability to rapidly prototype and iterate upon sensor designs to optimize performance for different applications and medical devices. Here, we present a new sensor fabrication method, which involves two-photon polymerization printing and integration of the printed structure onto the end-face of a single-mode optical fiber. The active elements of the sensor were a pressure-sensitive diaphragm and an intermediate temperature-sensitive spacer that was insensitive to changes in external pressure. Deflection of the diaphragm and thermal expansion the spacer relative to the fiber end-face were monitored using phase-resolved low coherence interferometry. A pressure sensitivity of 0.031 rad/mmHg across the range of 760 to 1060 mmHg (absolute pressure), and a temperature sensitivity of 1.2 mrad/oC across the range 20 to 45oC were observed. This method will enable the fabrication of a wide range of fiber-optic sensors with pressure and temperature sensitivities suitable for guiding minimally invasive surgery.}
}