TY  - INPR
ID  - discovery10061670
N2  - To improve health care for older persons, we need to learn more about ageing, e.g. identify protective factors and early markers for diseases. The Gothenburg H70 Birth Cohort Studies (the H70 studies) are multidisciplinary epidemiological studies examining representative birth cohorts of older populations in Gothenburg, Sweden. So far, six birth cohorts of 70-year-olds have been examined over time, and examinations have been virtually identical between studies. This paper describes the study procedures for the baseline examination of the Birth cohort 1944, conducted in 2014-16. In this study, all men and women born 1944 on specific dates, and registered as residents in Gothenburg, were eligible for participation (n?=?1839). A total of 1203 (response rate 72.2%; 559 men and 644 women; mean age 70.5 years) agreed to participate in the study. The study comprised sampling of blood and cerebrospinal fluid, psychiatric, cognitive, and physical health examinations, examinations of genetics and family history, use of medications, social factors, functional ability and disability, physical fitness and activity, body composition, lung function, audiological and ophthalmological examinations, diet, brain imaging, as well as a close informant interview, and qualitative studies. As in previous examinations, data collection serves as a basis for future longitudinal follow-up examinations. The research gained from the H70 studies has clinical relevance in relation to prevention, early diagnosis, clinical course, experience of illness, understanding pathogenesis and prognosis. Results will increase our understanding of ageing and inform service development, which may lead to enhanced quality of care for older persons.
SN  - 1573-7284
UR  - https://doi.org/10.1007/s10654-018-0459-8
JF  - European Journal of Epidemiology
KW  - Ageing
KW  -  Birth cohort
KW  -  H70 study
KW  -  Health
KW  -  Population sample
KW  -  Study design
A1  - Rydberg Sterner, T
A1  - Ahlner, F
A1  - Blennow, K
A1  - Dahlin-Ivanoff, S
A1  - Falk, H
A1  - Havstam Johansson, L
A1  - Hoff, M
A1  - Holm, M
A1  - Hörder, H
A1  - Jacobsson, T
A1  - Johansson, B
A1  - Johansson, L
A1  - Kern, J
A1  - Kern, S
A1  - Machado, A
A1  - Mellqvist Fässberg, M
A1  - Nilsson, J
A1  - Ribbe, M
A1  - Rothenberg, E
A1  - Rydén, L
A1  - Sadeghi, A
A1  - Sacuiu, S
A1  - Samuelsson, J
A1  - Sigström, R
A1  - Skoog, J
A1  - Thorvaldsson, V
A1  - Waern, M
A1  - Westman, E
A1  - Wetterberg, H
A1  - Zetterberg, H
A1  - Zetterberg, M
A1  - Zettergren, A
A1  - Östling, S
A1  - Skoog, I
TI  - The Gothenburg H70 Birth cohort study 2014-16: design, methods and study population
Y1  - 2018/11/13/
AV  - public
N1  - This article is distributed under the terms of the Creative
Commons Attribution 4.0 International License (http://creativeco
mmons.org/licenses/by/4.0/), which permits unrestricted use, distribution,
and reproduction in any medium, provided you give appropriate
credit to the original author(s) and the source, provide a link to the
Creative Commons license, and indicate if changes were made.
ER  -