TY - JOUR TI - Single-shot edge illumination x-ray phase-contrast tomography enabled by joint image reconstruction UR - http://dx.doi.org/10.1364/OL.42.000619 A1 - Chen, Y A1 - Guan, H A1 - Hagen, CK A1 - Olivo, A A1 - Anastasio, MA Y1 - 2017/02/01/ N2 - Edge illumination x-ray phase-contrast tomography (EIXPCT) is an emerging x-ray phase-contrast tomography technique for reconstructing the complex-valued x-ray refractive index distribution of an object. Conventional image reconstruction approaches for EIXPCT require multiple images to be acquired at each tomographic view angle. This contributes to prolonged data-acquisition times and elevated radiation doses, which can hinder in vivo applications. In this work, a new ?single-shot? method is proposed for joint reconstruction (JR) of the real and imaginaryvalued components of the refractive index distribution from a tomographic data set that contains only a single image acquired at each view angle. The proposed method is predicated on a nonlinear formulation of the inverse problem that is solved by using a gradient-based optimization method. The method is validated and investigated using computersimulated and experimental EIXPCT data sets. SP - 619 VL - 42 PB - OPTICAL SOC AMER SN - 1539-4794 IS - 3 JF - Optics Letters N1 - © 2017 Optical Society of America. This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions EP - 622 KW - Science & Technology KW - Physical Sciences KW - Optics KW - RETRIEVAL KW - ABSORPTION AV - public ID - discovery10058989 ER -