eprintid: 10058343 rev_number: 30 eprint_status: archive userid: 608 dir: disk0/10/05/83/43 datestamp: 2018-10-15 14:42:33 lastmod: 2021-10-25 22:45:46 status_changed: 2018-10-15 14:42:33 type: article metadata_visibility: show creators_name: Hare, N creators_name: Georgopoulos, P creators_name: Philips, KE creators_name: Johnson, JE creators_name: Seary, C creators_name: Panicker, JN creators_name: Stevenson, VL title: Improvement in overactive bladder symptoms in patients using functional electrical stimulation of the common peroneal nerve for walking ispublished: pub subjects: UCH divisions: UCL divisions: B02 divisions: C07 divisions: D07 keywords: Science & Technology, Life Sciences & Biomedicine, Rehabilitation, Functional electrical stimulation, FES, overactive bladder, OAB, percutaneous tibial nerve stimulation, PTNS, multiple sclerosis, MS, LOWER URINARY-TRACT note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: OBJECTIVE: Functional electrical stimulation is used to improve walking speed and reduces falls in people with upper motor neurone foot-drop. Following anecdotal observations of changes in bladder symptoms, an observational study was performed to explore this association further. DESIGN: A total of 47 consecutive patients attending for setup with functional electrical stimulation during a six-month period were asked to complete a questionnaire assessing bladder symptoms (ICIQ-OAB (International Consultation on Incontinence Questionnaire Overactive Bladder)) at baseline and three months during routine appointments. SUBJECTS: In all, 35 (75%) had multiple sclerosis and the other 12 subjects had a total of 9 diagnoses including 3 with stroke. Other conditions included cerebral palsy, motor neurone disease, hereditary spastic paraparesis, meningioma and spinocerebellar ataxias. RESULTS: Improvement in overactive bladder symptoms was not significant in the whole cohort, however, was significant in patients with multiple sclerosis (n = 35; mean change in ICIQ-OAB score 1.0, P = 0.043). Specifically, significant improvements were seen in urgency and urge incontinence in multiple sclerosis patients. There was a significant negative correlation of moderate strength within the multiple sclerosis cohort between baseline walking speed and subsequent change in ICIQ-OAB score (correlation coefficient of r = −0.40, P = 0.046). Thus, greater changes in bladder symptoms were seen with lower baseline walking speeds. CONCLUSION: The results of this exploratory study suggest that functional electrical stimulation use does improve overactive bladder symptoms in people with multiple sclerosis. Further exploration is needed to study this association and explore whether the mechanism is similar to that of percutaneous tibial nerve stimulation, a recognized treatment for the overactive bladder. date: 2018-10-01 date_type: published publisher: SAGE PUBLICATIONS LTD official_url: http://dx.doi.org/10.1177/0269215518780974 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green article_type_text: Article verified: verified_manual elements_id: 1564495 doi: 10.1177/0269215518780974 lyricists_name: Panicker, Jalesh lyricists_id: JPANI24 actors_name: Dewerpe, Marie actors_id: MDDEW97 actors_role: owner full_text_status: public publication: Clinical Rehabilitation volume: 32 number: 10 pagerange: 1357-1362 pages: 6 issn: 1477-0873 citation: Hare, N; Georgopoulos, P; Philips, KE; Johnson, JE; Seary, C; Panicker, JN; Stevenson, VL; (2018) Improvement in overactive bladder symptoms in patients using functional electrical stimulation of the common peroneal nerve for walking. Clinical Rehabilitation , 32 (10) pp. 1357-1362. 10.1177/0269215518780974 <https://doi.org/10.1177/0269215518780974>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10058343/1/FES%20Peroneal%20nerve-walking-ClinRehab.pdf