eprintid: 10056846 rev_number: 28 eprint_status: archive userid: 608 dir: disk0/10/05/68/46 datestamp: 2018-09-26 13:52:24 lastmod: 2021-12-06 00:07:18 status_changed: 2018-09-26 13:52:24 type: article metadata_visibility: show creators_name: Hirst, Y creators_name: Stoffel, S creators_name: Baio, G creators_name: McGregor, L creators_name: von Wagner, C title: Uptake of the English Bowel (Colorectal) Cancer Screening Programme: an update 5 years after the full roll-out ispublished: inpress divisions: UCL divisions: B02 divisions: D12 divisions: J96 divisions: G19 divisions: B04 divisions: C06 divisions: F61 keywords: Cancer screening uptake, Diffusion of innovation, Inequalities note: © 2018 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). abstract: BACKGROUND: The initial roll-out of the English Bowel (Colorectal) Cancer Screening programme, during 2006 and 2009, found uptake to be low (54%) and socially graded. The current analysis used data from 2010 to 2015 to test whether uptake is increasing and becoming less socially graded over time. METHODS: Postcode-derived area-level uptake of 4.4 million first-time invitees, stratified by gender and the year of the first invitation (2010-2015), was generated using the National Bowel Cancer Screening System. Data were limited to people aged 60-64 years. Binomial regression tested for variations in uptake by the year of invitation, gender, region, area-based socio-economic deprivation and area-based ethnic diversity. RESULTS: Overall, the first-time colorectal cancer (CRC) screening uptake across 6 years was 52% (n = 2,285,996/4,423,734) with a decline between 2010 and 2015 (53%, 54%, 52%, 50%, 49%, 49% respectively). Uptake continued to be socially graded between the most and the least deprived area-level socio-economic deprivation quintiles (43% vs 57%), the most and the least area-based ethnic diversity quintiles (41% vs 56%) and men and women (47% vs 56%). Multivariate analysis demonstrated the effects of year, deprivation, ethnicity and gender on uptake. The effect of deprivation was more pronounced in the most deprived area quintile between men and women (40% vs 47%) than the least deprived area quintile (52% vs 62% respectively). CONCLUSION: We did not find evidence of change in uptake patterns in CRC screening since its initial launch 10 years ago. The programme is unlikely to realise its full public health benefits and is en route to widening inequalities in CRC outcomes. date: 2018-09-07 date_type: published official_url: https://doi.org/10.1016/j.ejca.2018.07.135 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green article_type_text: Journal Article verified: verified_manual elements_id: 1585572 doi: 10.1016/j.ejca.2018.07.135 pii: S0959-8049(18)31120-1 language_elements: English lyricists_name: Baio, Gianluca lyricists_name: Hirst, Mary lyricists_name: McGregor, Lesley lyricists_name: Stoffel, Sandro lyricists_name: Von Wagner, Christian lyricists_id: GBAIO87 lyricists_id: MYHIR87 lyricists_id: LMCGR40 lyricists_id: STSTO43 lyricists_id: CVONW94 actors_name: Bracey, Alan actors_id: ABBRA90 actors_role: owner full_text_status: public publication: European Journal of Cancer event_location: England issn: 0959-8049 citation: Hirst, Y; Stoffel, S; Baio, G; McGregor, L; von Wagner, C; (2018) Uptake of the English Bowel (Colorectal) Cancer Screening Programme: an update 5 years after the full roll-out. European Journal of Cancer 10.1016/j.ejca.2018.07.135 <https://doi.org/10.1016/j.ejca.2018.07.135>. (In press). Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10056846/1/Wagner_Uptake%20of%20the%20English%20Bowel%20%28Colorectal%29%20Cancer%20Screening%20Programme.%20An%20update%205%20years%20after%20the%20full%20roll-ouy_AOP.pdf