eprintid: 10056846
rev_number: 28
eprint_status: archive
userid: 608
dir: disk0/10/05/68/46
datestamp: 2018-09-26 13:52:24
lastmod: 2021-12-06 00:07:18
status_changed: 2018-09-26 13:52:24
type: article
metadata_visibility: show
creators_name: Hirst, Y
creators_name: Stoffel, S
creators_name: Baio, G
creators_name: McGregor, L
creators_name: von Wagner, C
title: Uptake of the English Bowel (Colorectal) Cancer Screening Programme: an update 5 years after the full roll-out
ispublished: inpress
divisions: UCL
divisions: B02
divisions: D12
divisions: J96
divisions: G19
divisions: B04
divisions: C06
divisions: F61
keywords: Cancer screening uptake, Diffusion of innovation, Inequalities
note: © 2018 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
abstract: BACKGROUND: The initial roll-out of the English Bowel (Colorectal) Cancer Screening programme, during 2006 and 2009, found uptake to be low (54%) and socially graded. The current analysis used data from 2010 to 2015 to test whether uptake is increasing and becoming less socially graded over time. METHODS: Postcode-derived area-level uptake of 4.4 million first-time invitees, stratified by gender and the year of the first invitation (2010-2015), was generated using the National Bowel Cancer Screening System. Data were limited to people aged 60-64 years. Binomial regression tested for variations in uptake by the year of invitation, gender, region, area-based socio-economic deprivation and area-based ethnic diversity. RESULTS: Overall, the first-time colorectal cancer (CRC) screening uptake across 6 years was 52% (n = 2,285,996/4,423,734) with a decline between 2010 and 2015 (53%, 54%, 52%, 50%, 49%, 49% respectively). Uptake continued to be socially graded between the most and the least deprived area-level socio-economic deprivation quintiles (43% vs 57%), the most and the least area-based ethnic diversity quintiles (41% vs 56%) and men and women (47% vs 56%). Multivariate analysis demonstrated the effects of year, deprivation, ethnicity and gender on uptake. The effect of deprivation was more pronounced in the most deprived area quintile between men and women (40% vs 47%) than the least deprived area quintile (52% vs 62% respectively). CONCLUSION: We did not find evidence of change in uptake patterns in CRC screening since its initial launch 10 years ago. The programme is unlikely to realise its full public health benefits and is en route to widening inequalities in CRC outcomes.
date: 2018-09-07
date_type: published
official_url: https://doi.org/10.1016/j.ejca.2018.07.135
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_id: 1585572
doi: 10.1016/j.ejca.2018.07.135
pii: S0959-8049(18)31120-1
language_elements: English
lyricists_name: Baio, Gianluca
lyricists_name: Hirst, Mary
lyricists_name: McGregor, Lesley
lyricists_name: Stoffel, Sandro
lyricists_name: Von Wagner, Christian
lyricists_id: GBAIO87
lyricists_id: MYHIR87
lyricists_id: LMCGR40
lyricists_id: STSTO43
lyricists_id: CVONW94
actors_name: Bracey, Alan
actors_id: ABBRA90
actors_role: owner
full_text_status: public
publication: European Journal of Cancer
event_location: England
issn: 0959-8049
citation:        Hirst, Y;    Stoffel, S;    Baio, G;    McGregor, L;    von Wagner, C;      (2018)    Uptake of the English Bowel (Colorectal) Cancer Screening Programme: an update 5 years after the full roll-out.                   European Journal of Cancer        10.1016/j.ejca.2018.07.135 <https://doi.org/10.1016/j.ejca.2018.07.135>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10056846/1/Wagner_Uptake%20of%20the%20English%20Bowel%20%28Colorectal%29%20Cancer%20Screening%20Programme.%20An%20update%205%20years%20after%20the%20full%20roll-ouy_AOP.pdf