TY  - JOUR
UR  - http://dx.doi.org/10.1364/BOE.9.004317
PB  - OPTICAL SOC AMER
TI  - Fast adaptive optics scanning light ophthalmoscope retinal montaging
AV  - public
SP  - 4317
A1  - Davidson, B
A1  - Kalitzeos, A
A1  - Carroll, J
A1  - Dubra, A
A1  - Ourselin, S
A1  - Michaelides, M
A1  - Bergeles, C
KW  - Science & Technology
KW  -  Life Sciences & Biomedicine
KW  -  Physical Sciences
KW  -  Biochemical Research Methods
KW  -  Optics
KW  -  Radiology
KW  -  Nuclear Medicine & Medical Imaging
KW  -  Biochemistry & Molecular Biology
KW  -  IMAGE
IS  - 9
EP  - 4328
SN  - 2156-7085
Y1  - 2018/09/01/
N2  - The field of view of high-resolution ophthalmoscopes that require the use of adaptive
optics (AO) wavefront correction is limited by the isoplanatic patch of the eye, which varies
across individual eyes and with the portion of the pupil used for illumination and/or imaging.
Therefore all current AO ophthalmoscopes have small fields of view comparable to, or smaller
than, the isoplanatic patch, and the resulting images have to be stitched off-line to create larger
montages. These montages are currently assembled either manually, by expert human graders, or
automatically, often requiring several hours per montage. This arguably limits the applicability
of AO ophthalmoscopy to studies with small cohorts and moreover, prevents the ability to review
a real-time captured montage of all locations during image acquisition to further direct targeted
imaging. In this work, we propose stitching the images with our novel algorithm, which uses
oriented fast rotated brief (ORB) descriptors, local sensitivity hashing, and by searching for a
?good enough? transformation, rather than the best possible, to achieve processing times of 1-2
minutes per montage of 250 images. Moreover, the proposed method produces montages which
are as accurate as previous methods, when considering the image similarity metrics: normalised
mutual information (NMI), and normalised cross correlation (NCC).
N1  - Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.(https://creativecommons.org/licenses/by/4.0/)
JF  - Biomedical Optics Express
ID  - discovery10056657
VL  - 9
ER  -