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<https://discovery.ucl.ac.uk/id/eprint/10052278> <http://purl.org/dc/terms/title> "Effects of the Collimator Magnification Factor in the Geometrical Calibration of SPECT Systems"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10052278> <http://purl.org/ontology/bibo/abstract> "In compact systems, precise measurement in the\r\nprojection space may be compromised due to minification.\r\nThe objective of this work is to investigate the impact of the\r\nmagnification factor in a model-based calibration procedure. This\r\nhas direct relevance to the geometrical calibration of the clinical\r\nINSERT camera.\r\nProjection data from three point sources were simulated for a\r\nsingle pinhole collimator with magnification and single pinhole\r\nand slit-slat collimators with minification, for 100 noise realizations\r\nand 3 count levels. Model-based calibration was performed\r\nto estimate geometric parameters and data corresponding to\r\na Derenzo phantom were simulated and reconstructed with\r\ntrue and worst-case estimates for each collimator. Experimental\r\nprojection data were acquired with an INSERT prototype\r\ncamera and four 99mTc line sources in different locations within\r\nthe FoV. The collimator-CoR distance was varied in order to\r\nobtain different minifications and model-based calibration was\r\nperformed.\r\nThe results from the simulations suggest that calibration is\r\nless robust when minification is present, with higher biased\r\ncalibration parameters, which result in activity underestimation.\r\nFor experimental data, estimated parameters improved with a\r\nhigher magnification factor, in line with the simulation results.\r\nHowever, some inconsistencies in the results suggest that there is\r\nstill room for improvements.\r\nTo conclude, geometric calibration of SPECT systems is more\r\nsensitive to minification than magnification, which will impact\r\nimage quality."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10052278> <http://purl.org/dc/terms/date> "2016-01-01" .
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