eprintid: 10052225
rev_number: 26
eprint_status: archive
userid: 608
dir: disk0/10/05/22/25
datestamp: 2018-07-12 07:53:48
lastmod: 2021-10-04 00:21:26
status_changed: 2018-07-12 07:53:48
type: article
metadata_visibility: show
creators_name: McNicholas, N
creators_name: Hutchinson, M
creators_name: McGuigan, C
creators_name: Chataway, J
title: 2017 McDonald diagnostic criteria: A review of the evidence
ispublished: inpress
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: The diagnosis of Multiple Sclerosis (MS) has continuously evolved, allowing for an earlier and more accurate diagnosis of MS over time. The McDonald Criteria for diagnosis of MS were originally proposed in 2001, with previous revisions in both 2005 and 2010. The International Panel on Diagnosis in MS have recently reviewed the 2010 McDonald Criteria, and made recommendations for the revised 2017 McDonald Criteria. Any revisions made relied entirely on the available evidence, and not expert opinion. In this review, we provide an overview of the recent 2017 revisions to the McDonald Criteria, focusing in particular on the motivating evidence behind the recommendations made. We also review the existing research around misdiagnosis in MS, as well as areas considered to be high priorities of research, currently lacking in sufficient evidence, which may influence future diagnostic criteria in years to come. Finally, we illustrate some clinical examples, to demonstrate the impact of new diagnostic criteria on time to MS diagnosis in a real-world setting.
date: 2018-06-21
date_type: published
official_url: http://dx.doi.org/10.1016/j.msard.2018.05.011
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_id: 1563985
doi: 10.1016/j.msard.2018.05.011
pii: S2211-0348(18)30151-2
lyricists_name: Chataway, Jeremy
lyricists_id: JCHAT72
actors_name: Dewerpe, Marie
actors_id: MDDEW97
actors_role: owner
full_text_status: public
publication: Multiple Sclerosis and Related Disorders
volume: 24
pagerange: 48-54
event_location: Netherlands
issn: 2211-0356
citation:        McNicholas, N;    Hutchinson, M;    McGuigan, C;    Chataway, J;      (2018)    2017 McDonald diagnostic criteria: A review of the evidence.                   Multiple Sclerosis and Related Disorders , 24    pp. 48-54.    10.1016/j.msard.2018.05.011 <https://doi.org/10.1016/j.msard.2018.05.011>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10052225/1/Chataway_McD_MSARD_McNicholas%20et%20al.pdf