<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10051550> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/title> "Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/abstract> "Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Several biomarkers including proteins and lipids have been reported in MS cerebrospinal fluid (CSF), reflecting different aspects of the pathophysiology particularly of relapsing‐remitting MS (RRMS). Sulfatide, abundant in the myelin sheath and a proposed target for autoimmune attack in MS, has been reported altered in MS CSF. Here, we investigated the potential of CSF sulfatide and its isoforms as biomarkers in MS. A highly sensitive and quantitative mass spectrometry method was employed to determine levels of sulfatide isoforms in CSF from RRMS and progressive MS (PMS) patients, and healthy donors (HD). We demonstrate that levels of total CSF sulfatide and C24:1, C26:1, and C26:1‐OH isoforms were significantly increased in PMS compared with RRMS patients and HD, while C23:0‐OH was significantly decreased in CSF from PMS patients compared to the other two groups. Multivariate discriminant analysis showed that CSF sulfatide isoform pattern in PMS patients was distinct and non‐overlapping with that of RRMS patients and HD. Sulfatide levels did not correlate with tested biomarkers or clinical parameters. The results suggest that CSF sulfatide isoform levels may be used to discriminate the phenotype of MS and might play a role in the progression of the disease."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/date> "2018-08" .
<https://discovery.ucl.ac.uk/id/document/787190> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/volume> "146" .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/issue> "3" .
<https://discovery.ucl.ac.uk/id/org/ext-69575aab272d692ae22e92dad044c2a2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> .
<https://discovery.ucl.ac.uk/id/org/ext-69575aab272d692ae22e92dad044c2a2> <http://xmlns.com/foaf/0.1/name> "WILEY"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/publication/ext-14714159> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-14714159> <http://xmlns.com/foaf/0.1/name> "Journal of Neurochemistry"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/publication/ext-14714159> <http://purl.org/ontology/bibo/issn> "14714159" .
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<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-0b0ad8f3822b5bacc77327d20c95c34e> .
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<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
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<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-afb7a3ec50ea62737cdeb54241fbaafd> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-afb7a3ec50ea62737cdeb54241fbaafd> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-56dd5608b0833d1ab0f0c5bc3fcc4c3d> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-56dd5608b0833d1ab0f0c5bc3fcc4c3d> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f3c0f49b75c1663331c6998c3cd5aedf> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-f3c0f49b75c1663331c6998c3cd5aedf> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-9141fcd74db33792b55682fa7185f075> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-9141fcd74db33792b55682fa7185f075> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-fffc8688aa579e1496c913c32daf3289> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-fffc8688aa579e1496c913c32daf3289> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ec8f703e4ced3d611daa4b08f08ab7d0> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-ec8f703e4ced3d611daa4b08f08ab7d0> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-99ce82e7e1ad8115daf05775adf48881> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-99ce82e7e1ad8115daf05775adf48881> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-7e12195e5d3e497e2834d325d979ebbb> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-7e12195e5d3e497e2834d325d979ebbb> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e413108ceea30043df76eca69f06318b> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10051550#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10051550#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-e413108ceea30043df76eca69f06318b> .
<https://discovery.ucl.ac.uk/id/person/ext-e413108ceea30043df76eca69f06318b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-e413108ceea30043df76eca69f06318b> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e413108ceea30043df76eca69f06318b> <http://xmlns.com/foaf/0.1/familyName> "Blomqvist"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e413108ceea30043df76eca69f06318b> <http://xmlns.com/foaf/0.1/name> "M Blomqvist"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-fffc8688aa579e1496c913c32daf3289> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-fffc8688aa579e1496c913c32daf3289> <http://xmlns.com/foaf/0.1/givenName> "H"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-fffc8688aa579e1496c913c32daf3289> <http://xmlns.com/foaf/0.1/familyName> "Zetterberg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-fffc8688aa579e1496c913c32daf3289> <http://xmlns.com/foaf/0.1/name> "H Zetterberg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-99ce82e7e1ad8115daf05775adf48881> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-99ce82e7e1ad8115daf05775adf48881> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-99ce82e7e1ad8115daf05775adf48881> <http://xmlns.com/foaf/0.1/familyName> "Lycke"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-99ce82e7e1ad8115daf05775adf48881> <http://xmlns.com/foaf/0.1/name> "J Lycke"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-56dd5608b0833d1ab0f0c5bc3fcc4c3d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-56dd5608b0833d1ab0f0c5bc3fcc4c3d> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-56dd5608b0833d1ab0f0c5bc3fcc4c3d> <http://xmlns.com/foaf/0.1/familyName> "Ståhlman"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-56dd5608b0833d1ab0f0c5bc3fcc4c3d> <http://xmlns.com/foaf/0.1/name> "M Ståhlman"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ec8f703e4ced3d611daa4b08f08ab7d0> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ec8f703e4ced3d611daa4b08f08ab7d0> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ec8f703e4ced3d611daa4b08f08ab7d0> <http://xmlns.com/foaf/0.1/familyName> "Borén"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ec8f703e4ced3d611daa4b08f08ab7d0> <http://xmlns.com/foaf/0.1/name> "J Borén"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7e12195e5d3e497e2834d325d979ebbb> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-7e12195e5d3e497e2834d325d979ebbb> <http://xmlns.com/foaf/0.1/givenName> "SL"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7e12195e5d3e497e2834d325d979ebbb> <http://xmlns.com/foaf/0.1/familyName> "Cardell"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7e12195e5d3e497e2834d325d979ebbb> <http://xmlns.com/foaf/0.1/name> "SL Cardell"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0b0ad8f3822b5bacc77327d20c95c34e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-0b0ad8f3822b5bacc77327d20c95c34e> <http://xmlns.com/foaf/0.1/givenName> "L"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0b0ad8f3822b5bacc77327d20c95c34e> <http://xmlns.com/foaf/0.1/familyName> "Novakova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0b0ad8f3822b5bacc77327d20c95c34e> <http://xmlns.com/foaf/0.1/name> "L Novakova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-346d7bd1879061164f288dc341ba3b1e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-346d7bd1879061164f288dc341ba3b1e> <http://xmlns.com/foaf/0.1/givenName> "AK"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-346d7bd1879061164f288dc341ba3b1e> <http://xmlns.com/foaf/0.1/familyName> "Singh"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-346d7bd1879061164f288dc341ba3b1e> <http://xmlns.com/foaf/0.1/name> "AK Singh"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-afb7a3ec50ea62737cdeb54241fbaafd> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-afb7a3ec50ea62737cdeb54241fbaafd> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-afb7a3ec50ea62737cdeb54241fbaafd> <http://xmlns.com/foaf/0.1/familyName> "Axelsson"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-afb7a3ec50ea62737cdeb54241fbaafd> <http://xmlns.com/foaf/0.1/name> "M Axelsson"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f3c0f49b75c1663331c6998c3cd5aedf> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f3c0f49b75c1663331c6998c3cd5aedf> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f3c0f49b75c1663331c6998c3cd5aedf> <http://xmlns.com/foaf/0.1/familyName> "Adiels"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f3c0f49b75c1663331c6998c3cd5aedf> <http://xmlns.com/foaf/0.1/name> "M Adiels"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9141fcd74db33792b55682fa7185f075> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-9141fcd74db33792b55682fa7185f075> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9141fcd74db33792b55682fa7185f075> <http://xmlns.com/foaf/0.1/familyName> "Malmeström"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9141fcd74db33792b55682fa7185f075> <http://xmlns.com/foaf/0.1/name> "C Malmeström"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/ArticleEPrint> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/repository> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/787190> .
<https://discovery.ucl.ac.uk/id/document/787190> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery.ucl.ac.uk/id/document/787190> <http://www.w3.org/2000/01/rdf-schema#label> "Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS (Text)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://purl.org/dc/elements/1.1/hasVersion> <https://discovery.ucl.ac.uk/id/document/787190> .
<https://discovery.ucl.ac.uk/id/eprint/10051550> <http://eprints.org/ontology/hasAccepted> <https://discovery.ucl.ac.uk/id/document/787190> .
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