TY  - JOUR
JF  - The British Journal of Psychiatry
VL  - 212
PB  - ROYAL COLL PSYCHIATRISTS
SN  - 1472-1465
IS  - 1
AV  - public
ID  - discovery10048623
N1  - COPYRIGHT: © The Royal College of Psychiatrists 2018
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
EP  - 56
TI  - Accuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other mental disorders in early pregnancy
N2  - Background: There is limited evidence on the prevalence and identification of antenatal mental
disorders.
Aims: To investigate 1) prevalence of mental disorders in early pregnancy; 2) diagnostic accuracy of
depression-screening (Whooley) questions, compared with the Edinburgh Postnatal Depression
Scale (EPDS), against the Structured Clinical Interview DSM-IV-TR.
Method: Cross-sectional survey of women responding to Whooley questions asked at first antenatal
appointment. Women responding positively and a random sample of women responding negatively
were invited to participate.
Results: Population prevalence was 27% (95%CI 22-32%): 11% (95%CI 8-14%) depression, 15%
(95%CI 11-19%) anxiety disorders, 2% (95%CI 1-4%) obsessive-compulsive disorder, 0.8% (95%CI 0-
1%) PTSD, 2% (95%CI 0.4-3%) eating disorders, 0.03% (95%CI 0-0.2%) bipolar disorder, 0.7% (95%CI
0-1%) borderline personality disorder. For identification of depression, likelihood ratios were 8.2
(Whooley) and 9.8 (EPDS). Diagnostic accuracy was similar in identifying any disorder (likelihood
ratios 5.8 and 6).
Conclusions: Endorsement of Whooley questions in pregnancy indicates the need for a clinical
assessment of diagnosis and could be implemented when maternity professionals have been
appropriately trained on how to ask the questions sensitively, in settings where a clear referral and
care pathway is available.
SP  - 50
UR  - http://doi.org/10.1192/bjp.2017.9
A1  - Howard, LM
A1  - Ryan, EG
A1  - Trevillion, K
A1  - Anderson, F
A1  - Bick, D
A1  - Bye, A
A1  - Byford, S
A1  - O'Connor, S
A1  - Sands, P
A1  - Demilew, J
A1  - Milgrom, J
A1  - Pickles, A
Y1  - 2018/01/04/
ER  -