TY - JOUR JF - The British Journal of Psychiatry VL - 212 PB - ROYAL COLL PSYCHIATRISTS SN - 1472-1465 IS - 1 AV - public ID - discovery10048623 N1 - COPYRIGHT: © The Royal College of Psychiatrists 2018 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. EP - 56 TI - Accuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other mental disorders in early pregnancy N2 - Background: There is limited evidence on the prevalence and identification of antenatal mental disorders. Aims: To investigate 1) prevalence of mental disorders in early pregnancy; 2) diagnostic accuracy of depression-screening (Whooley) questions, compared with the Edinburgh Postnatal Depression Scale (EPDS), against the Structured Clinical Interview DSM-IV-TR. Method: Cross-sectional survey of women responding to Whooley questions asked at first antenatal appointment. Women responding positively and a random sample of women responding negatively were invited to participate. Results: Population prevalence was 27% (95%CI 22-32%): 11% (95%CI 8-14%) depression, 15% (95%CI 11-19%) anxiety disorders, 2% (95%CI 1-4%) obsessive-compulsive disorder, 0.8% (95%CI 0- 1%) PTSD, 2% (95%CI 0.4-3%) eating disorders, 0.03% (95%CI 0-0.2%) bipolar disorder, 0.7% (95%CI 0-1%) borderline personality disorder. For identification of depression, likelihood ratios were 8.2 (Whooley) and 9.8 (EPDS). Diagnostic accuracy was similar in identifying any disorder (likelihood ratios 5.8 and 6). Conclusions: Endorsement of Whooley questions in pregnancy indicates the need for a clinical assessment of diagnosis and could be implemented when maternity professionals have been appropriately trained on how to ask the questions sensitively, in settings where a clear referral and care pathway is available. SP - 50 UR - http://doi.org/10.1192/bjp.2017.9 A1 - Howard, LM A1 - Ryan, EG A1 - Trevillion, K A1 - Anderson, F A1 - Bick, D A1 - Bye, A A1 - Byford, S A1 - O'Connor, S A1 - Sands, P A1 - Demilew, J A1 - Milgrom, J A1 - Pickles, A Y1 - 2018/01/04/ ER -