eprintid: 10048537
rev_number: 21
eprint_status: archive
userid: 608
dir: disk0/10/04/85/37
datestamp: 2018-05-17 14:35:00
lastmod: 2021-09-24 22:07:16
status_changed: 2018-05-17 14:35:00
type: article
metadata_visibility: show
creators_name: Clark, JE
creators_name: Watson, S
creators_name: Friston, KJ
title: What is mood? A computational perspective
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F83
note: © Cambridge University Press 2018
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
abstract: The neurobiological understanding of mood, and by extension mood disorders, remains elusive despite decades of research implicating several neuromodulator systems. This review considers a new approach based on existing theories of functional brain organisation. The free energy principle (a.k.a. active inference), and its instantiation in the Bayesian brain, offers a complete and simple formulation of mood. It has been proposed that emotions reflect the precision of – or certainty about – the predicted sensorimotor/interoceptive consequences of action. By extending this reasoning, in a hierarchical setting, we suggest mood states act as (hyper) priors over uncertainty (i.e. emotions). Here, we consider the same computational pathology in the proprioceptive and interoceptive (behavioural and autonomic) domain in order to furnish an explanation for mood disorders. This formulation reconciles several strands of research at multiple levels of enquiry.
date: 2018-10
date_type: published
official_url: http://dx.doi.org/10.1017/S0033291718000430
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
article_type_text: Article in Press
verified: verified_manual
elements_id: 1541952
doi: 10.1017/S0033291718000430
lyricists_name: Friston, Karl
lyricists_id: KJFRI52
actors_name: Barczynska, Patrycja
actors_id: PBARC91
actors_role: owner
full_text_status: public
publication: Psychological Medicine
volume: 48
number: 14
pagerange: 2277-2284
issn: 1469-8978
citation:        Clark, JE;    Watson, S;    Friston, KJ;      (2018)    What is mood? A computational perspective.                   Psychological Medicine , 48  (14)   pp. 2277-2284.    10.1017/S0033291718000430 <https://doi.org/10.1017/S0033291718000430>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10048537/1/what_is_mood_a_computational_perspective.pdf