eprintid: 10046224
rev_number: 36
eprint_status: archive
userid: 608
dir: disk0/10/04/62/24
datestamp: 2018-04-10 16:11:02
lastmod: 2021-12-13 23:42:59
status_changed: 2018-04-10 16:11:02
type: article
metadata_visibility: show
creators_name: Stefler, D
creators_name: Azarova, A
creators_name: Irdam, D
creators_name: Scheiring, G
creators_name: Murphy, M
creators_name: McKee, M
creators_name: King, L
creators_name: Bobak, M
title: Smoking, alcohol and cancer mortality in Eastern European men: Findings from the PrivMort retrospective cohort study
ispublished: inpress
divisions: UCL
divisions: B02
divisions: D12
divisions: G19
keywords: Eastern Europe, Smoking, alcohol consumption, cancer, mortality rate
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: Eastern European men have among the highest cancer mortality rates globally. Prevalence of smoking and alcohol intake in this region is also high. The aim of this study was to calculate population attributable risk fraction (PARF) of cancer deaths from smoking and alcohol in Russia, Belarus and Hungary, and to examine the contribution of these lifestyle factors to differences in male cancer mortality in the three countries. Data was collected as part of the PrivMort retrospective cohort study. Randomly selected participants living in mid-size towns in Russia, Belarus and Hungary provided information on smoking habits, alcohol consumption, vital status and cause of death (if applicable) of male relatives (fathers, siblings and partners). PARF of cancer deaths (age 35 to 79) due to smoking, alcohol consumption and both combined was estimated between 2001 and 2013. Among 72,190 men, 4,702 died of cancer. Age standardized cancer mortality rates were similar to official data in all three countries. The estimated PARF (95% CI) associated with measures of smoking, alcohol consumption, both combined, and overall smoking or drinking were 25% (19-30), 2% (0-4), 29% (19-39) 43% (32-53) in Russia, 18% (8-28), 2% (-1-6), 28% (20-35), 38% (25-50) in Belarus, and 17% (13-20), 1% (0-3), 25% (20-30) 35% (28-42) in Hungary, respectively. These results suggest that in Eastern Europe, at least one third of cancer deaths in males may have been attributable to smoking and/or alcohol consumption in recent years. Health policies targeting these lifestyle factors can have a major impact on population health. This article is protected by copyright. All rights reserved.
date: 2018-03-26
date_type: published
official_url: https://doi.org/10.1002/ijc.31406
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_id: 1545480
doi: 10.1002/ijc.31406
lyricists_name: Bobak, Martin
lyricists_name: Stefler, Denes
lyricists_id: MBOBA10
lyricists_id: DSTEF71
actors_name: Stacey, Thomas
actors_id: TSSTA20
actors_role: owner
full_text_status: public
publication: International Journal of Cancer
event_location: United States
issn: 1097-0215
citation:        Stefler, D;    Azarova, A;    Irdam, D;    Scheiring, G;    Murphy, M;    McKee, M;    King, L;           Stefler, D;  Azarova, A;  Irdam, D;  Scheiring, G;  Murphy, M;  McKee, M;  King, L;  Bobak, M;   - view fewer <#>    (2018)    Smoking, alcohol and cancer mortality in Eastern European men: Findings from the PrivMort retrospective cohort study.                   International Journal of Cancer        10.1002/ijc.31406 <https://doi.org/10.1002/ijc.31406>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10046224/1/ijc_31406%28accepted%29.pdf
document_url: https://discovery.ucl.ac.uk/id/eprint/10046224/7/Bobak%20Supplementary_material.pdf