<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/title> "Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/abstract> "Cell size and shape affect cellular processes such as cell survival, growth and differentiation1,2,3,4, thus establishing cell geometry as a fundamental regulator of cell physiology. The contributions of the cytoskeleton, specifically actomyosin tension, to these effects have been described, but the exact biophysical mechanisms that translate changes in cell geometry to changes in cell behaviour remain mostly unresolved. Using a variety of innovative materials techniques, we demonstrate that the nanostructure and lipid assembly within the cell plasma membrane are regulated by cell geometry in a ligand-independent manner. These biophysical changes trigger signalling events involving the serine/threonine kinase Akt/protein kinase B (PKB) that direct cell-geometry-dependent mesenchymal stem cell differentiation. Our study defines a central regulatory role by plasma membrane ordered lipid raft microdomains in modulating stem cell differentiation with potential translational applications."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/date> "2018-02-12" .
<https://discovery.ucl.ac.uk/id/document/641279> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/volume> "17" .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/issue> "3" .
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<https://discovery.ucl.ac.uk/id/org/ext-1c63d9cb7ce409aca2e1962714982576> <http://xmlns.com/foaf/0.1/name> "NATURE PUBLISHING GROUP"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/publication/ext-14764660> <http://xmlns.com/foaf/0.1/name> "Nature Materials"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/publication/ext-14764660> <http://www.w3.org/2002/07/owl#sameAs> <urn:issn:14764660> .
<https://discovery.ucl.ac.uk/id/publication/ext-14764660> <http://purl.org/ontology/bibo/issn> "14764660" .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
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<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-5a4055626e7ebacda80d113fcda8aa68> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-dcac7bee26ae632ebbe85df5fdd8d581> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-dcac7bee26ae632ebbe85df5fdd8d581> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-8aeed8b7764981c566277cf6412962b1> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-8aeed8b7764981c566277cf6412962b1> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4e657eb45789cc105d77570788b5a0f9> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-4e657eb45789cc105d77570788b5a0f9> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-391552025132cdabb3351cffc30b5fa4> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-391552025132cdabb3351cffc30b5fa4> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-c700b22701de50ee8ede6811c1e03d89> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-c700b22701de50ee8ede6811c1e03d89> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-854ca9859eecd406136d731d733347a8> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-854ca9859eecd406136d731d733347a8> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-16c25153ec9d572ab9f7c0eb308f5096> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-16c25153ec9d572ab9f7c0eb308f5096> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-961e44feaaa5324822fb27975483a10f> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-961e44feaaa5324822fb27975483a10f> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-75310b319ad8d7b0d8ff92a61ef52853> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-75310b319ad8d7b0d8ff92a61ef52853> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-62735ac8be21665c9bed5a2e211b38c2> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-62735ac8be21665c9bed5a2e211b38c2> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ad08375ad41ef3c7d2aa40236d0e42bf> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-ad08375ad41ef3c7d2aa40236d0e42bf> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ca8cf353eb7236bb00a455705ad8e39b> .
<https://discovery.ucl.ac.uk/id/eprint/10045875> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10045875#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10045875#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-ca8cf353eb7236bb00a455705ad8e39b> .
<https://discovery.ucl.ac.uk/id/person/ext-4e657eb45789cc105d77570788b5a0f9> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-4e657eb45789cc105d77570788b5a0f9> <http://xmlns.com/foaf/0.1/givenName> "C-M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e657eb45789cc105d77570788b5a0f9> <http://xmlns.com/foaf/0.1/familyName> "Horejs"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e657eb45789cc105d77570788b5a0f9> <http://xmlns.com/foaf/0.1/name> "C-M Horejs"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-961e44feaaa5324822fb27975483a10f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-961e44feaaa5324822fb27975483a10f> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-961e44feaaa5324822fb27975483a10f> <http://xmlns.com/foaf/0.1/familyName> "Kallepitis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-961e44feaaa5324822fb27975483a10f> <http://xmlns.com/foaf/0.1/name> "C Kallepitis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16c25153ec9d572ab9f7c0eb308f5096> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-16c25153ec9d572ab9f7c0eb308f5096> <http://xmlns.com/foaf/0.1/givenName> "H"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16c25153ec9d572ab9f7c0eb308f5096> <http://xmlns.com/foaf/0.1/familyName> "Autefage"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16c25153ec9d572ab9f7c0eb308f5096> <http://xmlns.com/foaf/0.1/name> "H Autefage"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ad08375ad41ef3c7d2aa40236d0e42bf> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ad08375ad41ef3c7d2aa40236d0e42bf> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ad08375ad41ef3c7d2aa40236d0e42bf> <http://xmlns.com/foaf/0.1/familyName> "Goldoni"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ad08375ad41ef3c7d2aa40236d0e42bf> <http://xmlns.com/foaf/0.1/name> "S Goldoni"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-dcac7bee26ae632ebbe85df5fdd8d581> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-dcac7bee26ae632ebbe85df5fdd8d581> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-dcac7bee26ae632ebbe85df5fdd8d581> <http://xmlns.com/foaf/0.1/familyName> "Bertazzo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-dcac7bee26ae632ebbe85df5fdd8d581> <http://xmlns.com/foaf/0.1/name> "S Bertazzo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-62735ac8be21665c9bed5a2e211b38c2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-62735ac8be21665c9bed5a2e211b38c2> <http://xmlns.com/foaf/0.1/givenName> "CS"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-62735ac8be21665c9bed5a2e211b38c2> <http://xmlns.com/foaf/0.1/familyName> "Chen"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-62735ac8be21665c9bed5a2e211b38c2> <http://xmlns.com/foaf/0.1/name> "CS Chen"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-854ca9859eecd406136d731d733347a8> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-854ca9859eecd406136d731d733347a8> <http://xmlns.com/foaf/0.1/givenName> "BK"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-854ca9859eecd406136d731d733347a8> <http://xmlns.com/foaf/0.1/familyName> "Robinson"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-854ca9859eecd406136d731d733347a8> <http://xmlns.com/foaf/0.1/name> "BK Robinson"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-75310b319ad8d7b0d8ff92a61ef52853> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-75310b319ad8d7b0d8ff92a61ef52853> <http://xmlns.com/foaf/0.1/givenName> "ADR"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-75310b319ad8d7b0d8ff92a61ef52853> <http://xmlns.com/foaf/0.1/familyName> "Hernandez"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-75310b319ad8d7b0d8ff92a61ef52853> <http://xmlns.com/foaf/0.1/name> "ADR Hernandez"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-391552025132cdabb3351cffc30b5fa4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-391552025132cdabb3351cffc30b5fa4> <http://xmlns.com/foaf/0.1/givenName> "SA"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-391552025132cdabb3351cffc30b5fa4> <http://xmlns.com/foaf/0.1/familyName> "Maynard"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-391552025132cdabb3351cffc30b5fa4> <http://xmlns.com/foaf/0.1/name> "SA Maynard"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c700b22701de50ee8ede6811c1e03d89> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-c700b22701de50ee8ede6811c1e03d89> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c700b22701de50ee8ede6811c1e03d89> <http://xmlns.com/foaf/0.1/familyName> "Attwood"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c700b22701de50ee8ede6811c1e03d89> <http://xmlns.com/foaf/0.1/name> "S Attwood"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca8cf353eb7236bb00a455705ad8e39b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ca8cf353eb7236bb00a455705ad8e39b> <http://xmlns.com/foaf/0.1/givenName> "MM"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca8cf353eb7236bb00a455705ad8e39b> <http://xmlns.com/foaf/0.1/familyName> "Stevens"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ca8cf353eb7236bb00a455705ad8e39b> <http://xmlns.com/foaf/0.1/name> "MM Stevens"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-5a4055626e7ebacda80d113fcda8aa68> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-5a4055626e7ebacda80d113fcda8aa68> <http://xmlns.com/foaf/0.1/givenName> "TC"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-5a4055626e7ebacda80d113fcda8aa68> <http://xmlns.com/foaf/0.1/familyName> "von Erlach"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-5a4055626e7ebacda80d113fcda8aa68> <http://xmlns.com/foaf/0.1/name> "TC von Erlach"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8aeed8b7764981c566277cf6412962b1> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
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