eprintid: 10045243 rev_number: 22 eprint_status: archive userid: 608 dir: disk0/10/04/52/43 datestamp: 2018-03-14 17:18:34 lastmod: 2021-09-20 00:22:29 status_changed: 2018-03-14 17:18:34 type: article metadata_visibility: show creators_name: Melendez-Torres, GJ creators_name: Tancred, T creators_name: Fletcher, A creators_name: Thomas, J creators_name: Campbell, R creators_name: Bonell, C title: Does integrated academic and health education prevent substance use? Systematic review and meta-analyses ispublished: inpress divisions: UCL divisions: B16 divisions: B14 divisions: J81 keywords: child social development, health education, substance use, systematic review note: Copyright © 2018 The Authors. Child: Care, Health and Development Published by John Wiley & Sons Ltd This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. abstract: BACKGROUND: Prevention of substance (alcohol, tobacco, illegal/legal drug) use in adolescents is a public health priority. As the scope for school-based health education is constrained in school timetables, interventions integrating academic and health education have gained traction in the UK and elsewhere, though evidence for their effectiveness remains unclear. We sought to synthesize the effectiveness of interventions integrating academic and health education for the prevention of substance use. METHODS: We searched 19 databases between November and December 2015, among other methods. We included randomized trials of interventions integrating academic and health education targeting school students aged 4-18 and reporting substance use outcomes. We excluded interventions for specific health-related subpopulations (e.g., children with behavioural difficulties). Data were extracted independently in duplicate. Outcomes were synthesized by school key stage (KS) using multilevel meta-analyses, for substance use, overall and by type. RESULTS: We identified 7 trials reporting substance use. Interventions reduced substance use generally in years 7-9 (KS3) based on 5 evaluations (d = -0.09, 95% CI [-0.17, -0.01], I2 = 35%), as well as in years 10-11 (KS4) based on 3 evaluations (-0.06, [-0.09, -0.02]; I2 = 0%). Interventions were broadly effective for reducing specific alcohol, tobacco, and drug use in both KS groups. CONCLUSIONS: Evidence quality was highly variable. Findings for years 3-6 and 12-13 could not be meta-analysed, and we could not assess publication bias. Interventions appear to have a small but significant effect reducing substance use. Specific methods of integrating academic and health education remain poorly understood. date: 2018-02-15 date_type: published official_url: http://dx.doi.org/10.1111/cch.12558 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green article_type_text: Journal Article verified: verified_manual elements_id: 1538402 doi: 10.1111/cch.12558 lyricists_name: Thomas, James lyricists_id: JTHOA32 actors_name: Bracey, Alan actors_id: ABBRA90 actors_role: owner full_text_status: public publication: Child: Care, Health and Development event_location: England issn: 1365-2214 citation: Melendez-Torres, GJ; Tancred, T; Fletcher, A; Thomas, J; Campbell, R; Bonell, C; (2018) Does integrated academic and health education prevent substance use? Systematic review and meta-analyses. Child: Care, Health and Development 10.1111/cch.12558 <https://doi.org/10.1111/cch.12558>. (In press). Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10045243/1/Melendez-Torres_et_al-2018-Child__Care%2C_Health_and_Development.pdf