eprintid: 10045033 rev_number: 27 eprint_status: archive userid: 608 dir: disk0/10/04/50/33 datestamp: 2018-05-16 15:19:07 lastmod: 2021-12-11 00:01:15 status_changed: 2018-05-16 15:19:07 type: article metadata_visibility: show creators_name: Siriwardhana, DD creators_name: Hardoon, S creators_name: Rait, G creators_name: Weerasinghe, MC creators_name: Walters, KR title: Prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries: a systematic review and meta-analysis ispublished: pub divisions: UCL divisions: B02 divisions: C07 divisions: D79 divisions: D12 divisions: G20 keywords: Low-income countries, Middle-income countries, Healthcare planning, WHO Global Health Library, Prevalence of frailty and prefrailty in LMICs note: © Article author(s) 2018. All rights reserved. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license (http://creativecommons.org/licenses/by-nc/4.0/). abstract: OBJECTIVE: To systematically review the research conducted on prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries (LMICs) and to estimate the pooled prevalence of frailty and prefrailty in community-dwelling older adults in LMICs. DESIGN: Systematic review and meta-analysis. PROSPERO registration number is CRD42016036083. DATA SOURCES: MEDLINE, EMBASE, AMED, Web of Science, CINAHL and WHO Global Health Library were searched from their inception to 12 September 2017. SETTING: Low-income and middle-income countries. PARTICIPANTS: Community-dwelling older adults aged ≥60 years. RESULTS: We screened 7057 citations and 56 studies were included. Forty-seven and 42 studies were included in the frailty and prefrailty meta-analysis, respectively. The majority of studies were from upper middle-income countries. One study was available from low-income countries. The prevalence of frailty varied from 3.9% (China) to 51.4% (Cuba) and prevalence of prefrailty ranged from 13.4% (Tanzania) to 71.6% (Brazil). The pooled prevalence of frailty was 17.4% (95% CI 14.4% to 20.7%, I²=99.2%) and prefrailty was 49.3% (95% CI 46.4% to 52.2%, I²=97.5%). The wide variation in prevalence rates across studies was largely explained by differences in frailty assessment method and the geographic region. These findings are for the studies with a minimum recruitment age 60, 65 and 70 years. CONCLUSION: The prevalence of frailty and prefrailty appears higher in community-dwelling older adults in upper middle-income countries compared with high-income countries, which has important implications for healthcare planning. There is limited evidence on frailty prevalence in lower middle-income and low-income countries. date: 2018-03 date_type: published official_url: http://dx.doi.org/10.1136/bmjopen-2017-018195 oa_status: green full_text_type: pub pmcid: PMC5855322 language: eng primo: open primo_central: open_green article_type_text: Journal Article verified: verified_manual elements_id: 1541079 doi: 10.1136/bmjopen-2017-018195 pii: bmjopen-2017-018195 language_elements: English lyricists_name: Hardoon, Sarah lyricists_name: Rait, Greta lyricists_name: Siriwardhana, Dhammika lyricists_name: Walters, Katherine lyricists_id: SHARD36 lyricists_id: GRAIT16 lyricists_id: JDDSI19 lyricists_id: KWALT44 actors_name: Kalinowski, Damian actors_id: DKALI47 actors_role: owner full_text_status: public publication: BMJ Open volume: 8 number: 3 article_number: e018195 event_location: England issn: 2044-6055 citation: Siriwardhana, DD; Hardoon, S; Rait, G; Weerasinghe, MC; Walters, KR; (2018) Prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries: a systematic review and meta-analysis. BMJ Open , 8 (3) , Article e018195. 10.1136/bmjopen-2017-018195 <https://doi.org/10.1136/bmjopen-2017-018195>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10045033/1/Siriwardhana_Prevalence%20of%20frailty%20and%20prefrailty%20among%20community-dwelling%20older%20adults%20in%20low-income%20and%20middle-income%20countries.%20A%20systematic%20review%20and%20meta-analysis_VoR.pdf