TY - JOUR ID - discovery10043386 N2 - The first step that is required to extract the correct information from a two-dimensional (2D) diffraction signature is to remove the background accurately. However, direct background subtraction inevitably overcorrects the signal as it does not take into account the attenuation by the sample. Other traditional background removal methods, such as the rolling ball technique, can separate sharp diffraction peaks of crystalline materials from their background. These methods are unsuitable for biological tissue, which is amorphous and does not have sharp diffraction peaks. This technical note proposes a novel method that combines peak fitting and experimental results to estimate the background for 2D XRD signals. SN - 1361-6560 UR - http://dx.doi.org/10.1088/1361-6560/aaac9e JF - Physics in Medicine & Biology KW - 2D XRD KW - X-ray diffraction KW - background removal. A1 - Zheng, Y A1 - Speller, R A1 - Griffiths, J TI - A novel method to remove the background from x-ray diffraction signal AV - public VL - 63 Y1 - 2018/03/21/ N1 - This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions. IS - 6 ER -