eprintid: 10042237 rev_number: 16 eprint_status: archive userid: 608 dir: disk0/10/04/22/37 datestamp: 2018-02-01 16:21:53 lastmod: 2018-02-07 12:06:05 status_changed: 2018-02-07 12:06:05 type: article metadata_visibility: show creators_name: Holmes, E creators_name: Purcell, DW creators_name: Carlyon, RP creators_name: Gockel, HE creators_name: Johnsrude, IS title: Attentional Modulation of Envelope-Following Responses at Lower (93-109 Hz) but Not Higher (217-233 Hz) Modulation Rates ispublished: pub divisions: B02 divisions: C07 divisions: D07 divisions: F83 keywords: attention, FFR, EFR, EEG, brainstem note: Copyright © The Author(s) 2017. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. abstract: Directing attention to sounds of different frequencies allows listeners to perceive a sound of interest, like a talker, in a mixture. Whether cortically generated frequency-specific attention affects responses as low as the auditory brainstem is currently unclear. Participants attended to either a high- or low-frequency tone stream, which was presented simultaneously and tagged with different amplitude modulation (AM) rates. In a replication design, we showed that envelope-following responses (EFRs) were modulated by attention only when the stimulus AM rate was slow enough for the auditory cortex to track-and not for stimuli with faster AM rates, which are thought to reflect 'purer' brainstem sources. Thus, we found no evidence of frequency-specific attentional modulation that can be confidently attributed to brainstem generators. The results demonstrate that different neural populations contribute to EFRs at higher and lower rates, compatible with cortical contributions at lower rates. The results further demonstrate that stimulus AM rate can alter conclusions of EFR studies. date: 2018-02 date_type: published official_url: https://doi.org/10.1007/s10162-017-0641-9 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1527763 doi: 10.1007/s10162-017-0641-9 pii: 10.1007/s10162-017-0641-9 lyricists_name: Holmes, Emma lyricists_id: EHOLM03 actors_name: Laslett, David actors_id: DLASL34 actors_role: owner full_text_status: public publication: Journal of the Association for Research in Otolaryngology volume: 19 number: 1 pagerange: 83-97 event_location: United States issn: 1438-7573 citation: Holmes, E; Purcell, DW; Carlyon, RP; Gockel, HE; Johnsrude, IS; (2018) Attentional Modulation of Envelope-Following Responses at Lower (93-109 Hz) but Not Higher (217-233 Hz) Modulation Rates. Journal of the Association for Research in Otolaryngology , 19 (1) pp. 83-97. 10.1007/s10162-017-0641-9 <https://doi.org/10.1007/s10162-017-0641-9>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10042237/1/10.1007%252Fs10162-017-0641-9.pdf