eprintid: 10042030 rev_number: 27 eprint_status: archive userid: 608 dir: disk0/10/04/20/30 datestamp: 2018-01-30 10:36:00 lastmod: 2021-09-23 22:29:02 status_changed: 2018-01-30 10:36:00 type: article metadata_visibility: show creators_name: Palmer, CE creators_name: Langbehn, D creators_name: Tabrizi, SJ creators_name: Papoutsi, M title: Test Retest Reliability of Measures Commonly Used to Measure Striatal Dysfunction across Multiple Testing Sessions: A Longitudinal Study ispublished: pub divisions: UCL divisions: B02 divisions: C07 divisions: D07 divisions: F86 keywords: Social Sciences, Psychology, Multidisciplinary, Psychology, reliability, longitudinal, cognitive function, cognitive impairment, inhibitory control, emotion recognition, striatal impairment, RESPONSE-INHIBITION, HUNTINGTONS-DISEASE, ALTERNATE FORMS, COMPATIBILITY, PREMANIFEST, DEMENTIA, BATTERY, TRAIL, HD note: © 2018 Palmer, Langbehn, Tabrizi and Papoutsi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. abstract: Cognitive impairment is common amongst many neurodegenerative movement disorders such as Huntington’s disease (HD) and Parkinson’s disease (PD) across multiple domains. There are many tasks available to assess different aspects of this dysfunction, however, it is imperative that these show high test–retest reliability if they are to be used to track disease progression or response to treatment in patient populations. Moreover, in order to ensure effects of practice across testing sessions are not misconstrued as clinical improvement in clinical trials, tasks which are particularly vulnerable to practice effects need to be highlighted. In this study we evaluated test–retest reliability in mean performance across three testing sessions of four tasks that are commonly used to measure cognitive dysfunction associated with striatal impairment: a combined Simon Stop-Signal Task; a modified emotion recognition task; a circle tracing task; and the trail making task. Practice effects were seen between sessions 1 and 2 across all tasks for the majority of dependent variables, particularly reaction time variables; some, but not all, diminished in the third session. Good test–retest reliability across all sessions was seen for the emotion recognition, circle tracing, and trail making test. The Simon interference effect and stop-signal reaction time (SSRT) from the combined-Simon-Stop-Signal task showed moderate test–retest reliability, however, the combined SSRT interference effect showed poor test–retest reliability. Our results emphasize the need to use control groups when tracking clinical progression or use pre-baseline training on tasks susceptible to practice effects. date: 2018-01-12 date_type: published publisher: FRONTIERS MEDIA SA official_url: http://dx.doi.org/10.3389/fpsyg.2017.02363 oa_status: green full_text_type: pub language: fre primo: open primo_central: open_green article_type_text: Article verified: verified_manual elements_id: 1525833 doi: 10.3389/fpsyg.2017.02363 lyricists_name: Palmer, Clare lyricists_name: Papoutsi, Marina lyricists_name: Tabrizi, Sarah lyricists_id: CPALM53 lyricists_id: MPAPO16 lyricists_id: SJTAB21 actors_name: Dewerpe, Marie actors_id: MDDEW97 actors_role: owner full_text_status: public publication: Frontiers in Psychology volume: 8 number: 2363 pages: 13 issn: 1664-1078 citation: Palmer, CE; Langbehn, D; Tabrizi, SJ; Papoutsi, M; (2018) Test Retest Reliability of Measures Commonly Used to Measure Striatal Dysfunction across Multiple Testing Sessions: A Longitudinal Study. Frontiers in Psychology , 8 (2363) 10.3389/fpsyg.2017.02363 <https://doi.org/10.3389/fpsyg.2017.02363>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10042030/7/Tabrizi_fpsyg-08-02363.pdf