TY - JOUR KW - death KW - outcome KW - TB surveillance KW - vital registration JF - The International Journal of Tuberculosis and Lung Disease A1 - Lalor, MK A1 - Mohiyuddin, T A1 - Uddin, T A1 - Thomas, HL A1 - Lipman, M A1 - Campbell, CNJ N1 - This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions. VL - 22 SP - 572 N2 - BACKGROUND: Accurate estimates of tuberculosis (TB) mortality are required to monitor progress towards the World Health Organization End TB goal of reducing TB deaths by 95% by 2035. We compared TB death data for England and Wales from the national surveillance system (Enhanced Tuberculosis Surveillance System [ETS]) and the vital registration system from the Office for National Statistics (ONS). METHODS: TB cases notified in ETS were matched to deaths in ONS (dONS) with International Classification of Diseases, Tenth Revision (ICD-10) codes indicating that TB caused/contributed to the death (A15?A19). Deaths captured in one but not both systems were assessed to identify if ONS captured all TB deaths and if there was under-notification of TB in ETS. We stratified deaths into active TB, TB sequelae, incidental deaths and not TB. RESULTS: Between 2005 and 2015, there were fewer deaths in ETS (dETS) than dONS with ICD-10 codes A15?A19 (n = 4207 vs. n = 6560); 57% of dETS were recorded as dONS and 53% of dONS were notified to ETS. A total of 9289 deaths were identified from dETS and dONS: 64% were due to active TB, 23% were TB sequelae, 6% were incidental and 7% were not TB. CONCLUSIONS: TB deaths in ETS and ONS differ substantially. Almost one third of TB deaths recorded by ONS are not due to active TB; this can be amended through coding changes. IS - 5 ID - discovery10040916 UR - https://doi.org/10.5588/ijtld.17.0695 EP - 578 TI - The challenge of estimating tuberculosis mortality accurately in England and Wales Y1 - 2018/05// AV - public ER -