eprintid: 10040877 rev_number: 26 eprint_status: archive userid: 608 dir: disk0/10/04/08/77 datestamp: 2018-01-05 09:32:02 lastmod: 2021-12-06 00:20:01 status_changed: 2018-01-05 09:32:02 type: article metadata_visibility: show creators_name: Pinnock, H creators_name: Parke, HL creators_name: Panagioti, M creators_name: Daines, L creators_name: Pearce, G creators_name: Epiphaniou, E creators_name: Bower, P creators_name: Sheikh, A creators_name: Griffiths, CJ creators_name: Taylor, SJC creators_name: PRISMS and RECURSIVE groups, title: Systematic meta-review of supported self-management for asthma: a healthcare perspective ispublished: pub divisions: UCL divisions: B02 divisions: C10 divisions: D17 divisions: D12 divisions: G20 keywords: Supported self-management, Asthma, Systematic meta-review, Health economic analysis, Meta-analysis note: Copyright © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. abstract: BACKGROUND: Supported self-management has been recommended by asthma guidelines for three decades; improving current suboptimal implementation will require commitment from professionals, patients and healthcare organisations. The Practical Systematic Review of Self-Management Support (PRISMS) meta-review and Reducing Care Utilisation through Self-management Interventions (RECURSIVE) health economic review were commissioned to provide a systematic overview of supported self-management to inform implementation. We sought to investigate if supported asthma self-management reduces use of healthcare resources and improves asthma control; for which target groups it works; and which components and contextual factors contribute to effectiveness. Finally, we investigated the costs to healthcare services of providing supported self-management. METHODS: We undertook a meta-review (systematic overview) of systematic reviews updated with randomised controlled trials (RCTs) published since the review search dates, and health economic meta-analysis of RCTs. Twelve electronic databases were searched in 2012 (updated in 2015; pre-publication update January 2017) for systematic reviews reporting RCTs (and update RCTs) evaluating supported asthma self-management. We assessed the quality of included studies and undertook a meta-analysis and narrative synthesis. RESULTS: A total of 27 systematic reviews (n = 244 RCTs) and 13 update RCTs revealed that supported self-management can reduce hospitalisations, accident and emergency attendances and unscheduled consultations, and improve markers of control and quality of life for people with asthma across a range of cultural, demographic and healthcare settings. Core components are patient education, provision of an action plan and regular professional review. Self-management is most effective when delivered in the context of proactive long-term condition management. The total cost (n = 24 RCTs) of providing self-management support is offset by a reduction in hospitalisations and accident and emergency visits (standard mean difference 0.13, 95% confidence interval -0.09 to 0.34). CONCLUSIONS: Evidence from a total of 270 RCTs confirms that supported self-management for asthma can reduce unscheduled care and improve asthma control, can be delivered effectively for diverse demographic and cultural groups, is applicable in a broad range of clinical settings, and does not significantly increase total healthcare costs. Informed by this comprehensive synthesis of the literature, clinicians, patient-interest groups, policy-makers and providers of healthcare services should prioritise provision of supported self-management for people with asthma as a core component of routine care. date: 2017-03-17 date_type: published official_url: http://doi.org/10.1186/s12916-017-0823-7 oa_status: green full_text_type: pub pmcid: PMC5356253 language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1519715 doi: 10.1186/s12916-017-0823-7 pii: 10.1186/s12916-017-0823-7 lyricists_name: Murray, Elizabeth lyricists_name: Newman, Stanton lyricists_id: EMURR90 lyricists_id: SPNEW17 actors_name: Waragoda Vitharana, Nimal actors_id: NWARR44 actors_role: owner full_text_status: public publication: BMC Medicine volume: 15 number: 1 article_number: 64 event_location: England issn: 1741-7015 citation: Pinnock, H; Parke, HL; Panagioti, M; Daines, L; Pearce, G; Epiphaniou, E; Bower, P; ... PRISMS and RECURSIVE groups; + view all <#> Pinnock, H; Parke, HL; Panagioti, M; Daines, L; Pearce, G; Epiphaniou, E; Bower, P; Sheikh, A; Griffiths, CJ; Taylor, SJC; PRISMS and RECURSIVE groups; - view fewer <#> (2017) Systematic meta-review of supported self-management for asthma: a healthcare perspective. BMC Medicine , 15 (1) , Article 64. 10.1186/s12916-017-0823-7 <https://doi.org/10.1186/s12916-017-0823-7>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10040877/1/s12916-017-0823-7.pdf