TY  - JOUR
N2  - Coding the distance to a future goal is an important function of a neural system supporting navigation. While some evidence indicates the hippocampus increases activity with proximity to the goal, others have found activity to decreases with proximity. To explore goal distance coding in the hippocampus we recorded from CA1 hippocampal place cells in rats as they navigated to learned goals in an event arena with a win-stay lose-shift rule. CA1 activity was positively correlated with the distance - decreasing with proximity to the goal. The stronger the correlation between distance to the goal and CA1 activity, the more successful navigation was in a given task session. Acceleration, but not speed, was also correlated with the distance to the goal. However, the relationship between CA1 activity and navigation performance was independent of variation in acceleration and variation in speed. These results help clarify the situations in which CA1 activity encodes navigationally relevant information and the extent to which it relates to behavior. This article is protected by copyright. All rights reserved.
IS  - 9
UR  - http://dx.doi.org/10.1002/hipo.22813
EP  - 658
ID  - discovery10039938
TI  - Hippocampal CA1 Activity Correlated with the Distance to the Goal and Navigation Performance
Y1  - 2018/09//
SN  - 1098-1063
AV  - public
A1  - Spiers, HJ
A1  - Olafsdottir, HF
A1  - Lever, C
JF  - Hippocampus
N1  - © 2017 The Authors. Hippocampus Published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
VL  - 28
SP  - 644
ER  -