eprintid: 10038973
rev_number: 22
eprint_status: archive
userid: 608
dir: disk0/10/03/89/73
datestamp: 2017-11-30 15:26:12
lastmod: 2021-12-05 00:45:32
status_changed: 2017-11-30 15:26:12
type: article
metadata_visibility: show
creators_name: Mahon, J
creators_name: Lifschitz, C
creators_name: Ludwig, T
creators_name: Thapar, N
creators_name: Glanville, J
creators_name: Miqdady, M
creators_name: Saps, M
creators_name: Quak, SH
creators_name: Lenoir Wijnkoop, I
creators_name: Edwards, M
creators_name: Wood, H
creators_name: Szajewska, H
title: The costs of functional gastrointestinal disorders and related signs and symptoms in infants: a systematic literature review and cost calculation for England
ispublished: pub
divisions: UCL
divisions: B02
divisions: D13
divisions: G22
keywords: community child health, functional bowel disorders, health economics
note: This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
abstract: OBJECTIVES: To estimate the cost of functional gastrointestinal disorders (FGIDs) and related signs and symptoms in infants to the third party payer and to parents. STUDY DESIGN: To estimate the cost of illness (COI) of infant FGIDs, a two-stage process was applied: a systematic literature review and a COI calculation. As no pertinent papers were found in the systematic literature review, a 'de novo' analysis was performed. For the latter, the potential costs for the third party payer (the National Health Service (NHS) in England) and for parents/carers for the treatment of FGIDs in infants were calculated, by using publicly available data. In constructing the calculation, estimates and assumptions (where necessary) were chosen to provide a lower bound (minimum) of the potential overall cost. In doing so, the interpretation of the calculation is that the true COI can be no lower than that estimated. RESULTS: Our calculation estimated that the total costs of treating FGIDs in infants in England were at least £72.3 million per year in 2014/2015 of which £49.1 million was NHS expenditure on prescriptions, community care and hospital treatment. Parents incurred £23.2 million in costs through purchase of over the counter remedies. CONCLUSIONS: The total cost presented here is likely to be a significant underestimate as only lower bound estimates were used where applicable, and for example, costs of alternative therapies, inpatient treatments or diagnostic tests, and time off work by parents could not be adequately estimated and were omitted from the calculation. The number and kind of prescribed products and products sold over the counter to treat FGIDs suggest that there are gaps between treatment guidelines, which emphasise parental reassurance and nutritional advice, and their implementation.
date: 2017-11
date_type: published
official_url: http://dx.doi.org/10.1136/bmjopen-2016-015594
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
article_type_text: Journal Article
verified: verified_manual
elements_id: 1511973
doi: 10.1136/bmjopen-2016-015594
pii: bmjopen-2016-015594
lyricists_name: Thapar, Nikhil
lyricists_id: NTHAP68
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
full_text_status: public
publication: BMJ Open
volume: 7
number: 11
article_number: e015594
event_location: England
issn: 2044-6055
citation:        Mahon, J;    Lifschitz, C;    Ludwig, T;    Thapar, N;    Glanville, J;    Miqdady, M;    Saps, M;                     ... Szajewska, H; + view all <#>        Mahon, J;  Lifschitz, C;  Ludwig, T;  Thapar, N;  Glanville, J;  Miqdady, M;  Saps, M;  Quak, SH;  Lenoir Wijnkoop, I;  Edwards, M;  Wood, H;  Szajewska, H;   - view fewer <#>    (2017)    The costs of functional gastrointestinal disorders and related signs and symptoms in infants: a systematic literature review and cost calculation for England.                   BMJ Open , 7  (11)    , Article e015594.  10.1136/bmjopen-2016-015594 <https://doi.org/10.1136/bmjopen-2016-015594>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10038973/1/e015594.full.pdf