eprintid: 10024256 rev_number: 24 eprint_status: archive userid: 608 dir: disk0/10/02/42/56 datestamp: 2017-10-08 07:38:56 lastmod: 2021-11-15 02:30:55 status_changed: 2017-10-24 14:28:23 type: article metadata_visibility: show creators_name: Eini, S creators_name: Shahhosseini, HR creators_name: Javidi, M creators_name: Sharifzadeh, M creators_name: Rashtchian, D title: Inherently safe and economically optimal design using multi-objective optimization: The case of a refrigeration cycle ispublished: pub divisions: UCL divisions: B04 divisions: C05 keywords: Science & Technology, Technology, Engineering, Environmental, Engineering, Chemical, Engineering, Inherent safety, Consequence modeling, Multi-objective optimization, Layout optimization, Simple refrigeration cycle, Pareto front, CONTROLLED PROCESS MODEL, OBJECTIVE OPTIMIZATION, BIODIESEL PRODUCTION, INTEGRATED DESIGN, DEVELOPMENT STAGE, DECISION-MAKING, RISK, TOOL, DISTILLATION, FRAMEWORK note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: The economic viability of industrial processes strongly depends on their safe and reliable operation. The method of inherent safe process design enables systematic consideration of safety measures in order to ensure process safe operation at the early stages of process design. The challenge is that the economic measures that are often considered for the design of industrial processes are often incommensurable with the safety measures. In the present research, a novel framework is proposed in which the safety criteria are quantified based on consequence modeling and aggregated with the economic performance using multi-objective optimization programming. The developed methodology was applied to the design of a simple refrigeration cycle. The optimization algorithm was NSGA-II. The results suggested a strong trade-off between the competing economic and safety objectives in terms of Pareto frontiers that clearly quantified the required compromise. It was observed that only with a minor increase in the capital investment, it is possible to significantly improve the safety. While the case of the refrigeration cycle was selected as a demonstrating case, the research methodology is to large extend general and deemed to be acceptable to design and operation of other industrial processes. date: 2016-09-16 date_type: published publisher: INST CHEMICAL ENGINEERS official_url: https://doi.org/10.1016/j.psep.2016.09.010 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green article_type_text: Article verified: verified_manual elements_id: 1426291 doi: 10.1016/j.psep.2016.09.010 lyricists_name: Sharifzadeh, Mahdi lyricists_id: MSHAB90 actors_name: Stacey, Thomas actors_id: TSSTA20 actors_role: owner full_text_status: public publication: Process Safety and Environmental Protection volume: 104 pagerange: 254-267 pages: 14 issn: 1744-3598 citation: Eini, S; Shahhosseini, HR; Javidi, M; Sharifzadeh, M; Rashtchian, D; (2016) Inherently safe and economically optimal design using multi-objective optimization: The case of a refrigeration cycle. Process Safety and Environmental Protection , 104 pp. 254-267. 10.1016/j.psep.2016.09.010 <https://doi.org/10.1016/j.psep.2016.09.010>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10024256/1/Sharifzadeh_Inherently%20safe%20and%20economically%20optimal%20design%20using%20multi-objective%20optimization_.pdf