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Number of items: 29.

2022

Matsuyama, A; Kalargyrou, AA; Smith, AJ; Ali, RR; Pearson, RA; (2022) A comprehensive atlas of Aggrecan, Versican, Neurocan and Phosphacan expression across time in wildtype retina and in retinal degeneration. Scientific Reports , 12 , Article 7282. 10.1038/s41598-022-11204-w. Green open access
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2021

Aghaizu, ND; Warre-Cornish, KM; Robinson, MR; Ali, RR; Pearson, RA; (2021) Tracking neuronal motility in live murine retinal explants. STAR Protocols , 2 (4) , Article 101008. 10.1016/j.xpro.2021.101008. Green open access
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Aghaizu, ND; Warre-Cornish, KM; Robinson, MR; Waldron, PV; Maswood, RN; Smith, AJ; Ali, RR; (2021) Repeated nuclear translocations underlie photoreceptor positioning and lamination of the outer nuclear layer in the mammalian retina. Cell Reports , 36 (5) , Article 109461. 10.1016/j.celrep.2021.109461. Green open access
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Hippert, C; Graca, AB; Basche, M; Kalargyrou, AA; Georgiadis, A; Ribeiro, J; Matsuyama, A; ... Pearson, RA; + view all (2021) RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration. Glia 10.1002/glia.24034. (In press). Green open access
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Kalargyrou, Aikaterini A; Basche, Mark; Hare, Aura; West, Emma L; Smith, Alexander J; Ali, Robin R; Pearson, Rachael A; (2021) Nanotube-like processes facilitate material transfer between photoreceptors. EMBO Reports , 22 , Article e53732. 10.15252/embr.202153732. Green open access
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Ribeiro, J; Procyk, CA; West, EL; O'Hara-Wright, M; Martins, MF; Khorasani, MM; Hare, A; ... Ali, RR; + view all (2021) Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors. Cell Reports , 35 (3) , Article 109022. 10.1016/j.celrep.2021.109022. Green open access
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2020

Langhe, R; Pearson, RA; (2020) Rebuilding the Retina: Prospects for Müller Glial-mediated Self-repair. Current Eye Research , 45 (3) pp. 349-360. 10.1080/02713683.2019.1669665. Green open access
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2019

Aldunate, EZ; Di Foggia, V; Di Marco, F; Hervas, LA; Ribeiro, JC; Holder, DL; Patel, A; ... Sowden, JC; + view all (2019) Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision. Scientific Reports , 9 , Article 2314. 10.1038/s41598-018-38294-9. Green open access
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2018

Gonzalez Cordero, A; Goh, D; Kruczek, K; Naeem, A; Fernando, M; Kleine Holthaus, S-M; Takaaki, M; ... Ali, RR; + view all (2018) Assessment of AAV vector tropisms for mouse and human pluripotent stem cell-derived RPE and photoreceptor cells. Human Gene Therapy , 29 (10) pp. 1124-1139. 10.1089/hum.2018.027. Green open access
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Kleine Holthaus, S-M; Ribeiro, J; Abelleira-Hervas, L; Pearson, RA; Duran, Y; Georgiadis, A; Sampson, RD; ... Ali, RR; + view all (2018) Prevention of Photoreceptor Cell Loss in a Cln6nclf Mouse Model of Batten Disease Requires CLN6 Gene Transfer to Bipolar Cells. Molecular Therapy , 26 (5) pp. 1343-1353. 10.1016/j.ymthe.2018.02.027. Green open access
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Pearson, RA; Ali, RR; (2018) Unlocking the Potential for Endogenous Repair to Restore Sight. Neuron , 100 (3) pp. 524-526. 10.1016/j.neuron.2018.10.035. Green open access
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Waldron, PV; Di Marco, F; Kruczek, K; Ribeiro, J; Graca, AB; Hippert, C; Aghaizu, ND; ... Pearson, RA; + view all (2018) Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner. Stem Cell Reports 10.1016/j.stemcr.2017.12.008. Green open access
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2017

Aghaizu, ND; Kruczek, K; Gonzalez-Cordero, A; Ali, RR; Pearson, RA; (2017) Chapter 8 - Pluripotent stem cells and their utility in treating photoreceptor degenerations. Progress in Brain Research , 231 pp. 191-223. 10.1016/bs.pbr.2017.01.001.

Gonzalez-Cordero, A; Kruczek, K; Naeem, A; Fernando, M; Kloc, M; Ribeiro, J; Goh, D; ... Ali, RR; + view all (2017) Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors. Stem Cell Reports 10.1016/j.stemcr.2017.07.022. (In press). Green open access
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Graca, AB; (2017) Assessment and modulation of gliosis in inherited eye disease and its impact on cell replacement therapy. Doctoral thesis , UCL (University College London). Green open access
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Kruczek, K; Gonzalez-Cordero, A; Goh, D; Naeem, A; Jonikas, M; Blackford, SJI; Kloc, M; ... Ali, RR; + view all (2017) Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration. Stem Cell Reports , 8 (6) pp. 1659-1674. 10.1016/j.stemcr.2017.04.030. Green open access
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Ovando-Roche, P; Georgiadis, A; Smith, AJ; Pearson, RA; Ali, RR; (2017) Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration. Current Stem Cell Reports , 3 (2) pp. 112-123. 10.1007/s40778-017-0078-4. Green open access
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2016

Aghaizu, ND; (2016) Mechanisms of rod photoreceptor motility in development and following transplantation. Doctoral thesis , UCL (University College London). Green open access
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Athanasiou, D; Aguila, M; Opefi, CA; South, K; Bellingham, J; Bevilacqua, D; Munro, PM; ... Cheetham, ME; + view all (2016) Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Human Molecular Genetics , 26 (2) pp. 305-319. 10.1093/hmg/ddw387. Green open access
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Pearson, RA; Gonzalez-Cordero, A; West, EL; Ribeiro, JR; Aghaizu, N; Goh, D; Sampson, RD; ... Ali, RR; + view all (2016) Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors. Nature Communications , 7 , Article 13029. 10.1038/ncomms13029. Green open access
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2015

Hippert, C; Graca, AB; Barber, AC; West, EL; Smith, AJ; Ali, RR; Pearson, RA; (2015) Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific. PLoS One , 10 (3) , Article e0120415. 10.1371/journal.pone.0120415. Green open access
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Hippert, C; Graca, AB; Pearson, RA; (2015) Gliosis Can Impede Integration Following Photoreceptor Transplantation into the Diseased Retina. In: Rickman, CB and LaVail, MM and Anderson, RE and Grimm, C and Hollyfield, J and Ash, J, (eds.) Retinal Degenerative Diseases: Mechanisms and Experimental Therapy. (pp. pp. 579-585). Springer: Cham, Switzerland. Green open access
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Jayakody, SA; Gonzalez-Cordero, A; Ali, RR; Pearson, RA; (2015) Cellular strategies for retinal repair by photoreceptor replacement. Progress in Retinal and Eye Research , 46 31 - 66. 10.1016/j.preteyeres.2015.01.003. Green open access
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Lakowski, J; Gonzalez-Cordero, A; West, EL; Han, YT; Welby, E; Naeem, A; Blackford, SJ; ... Sowden, JC; + view all (2015) Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell-Derived Self-Forming Retina. Stem Cells , 33 (8) pp. 2469-2482. 10.1002/stem.2051. Green open access
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2011

Buch, PK; Mihelec, M; Cottrill, P; Wilkie, SE; Pearson, RA; Duran, Y; West, EL; ... Hunt, DM; + view all (2011) Dominant Cone-Rod Dystrophy: A Mouse Model Generated by Gene Targeting of the GCAP1/Guca1a Gene. PLOS ONE , 6 (3) , Article e18089. 10.1371/journal.pone.0018089. Green open access
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Carvalho, LS; Xu, JH; Pearson, RA; Smith, AJ; Bainbridge, JW; Morris, LM; Fliesler, SJ; ... Ali, RR; + view all (2011) Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy. Human Molecular Genetics , 20 (16) 3161 - 3175. 10.1093/hmg/ddr218. Green open access
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Mihelec, M; Pearson, RA; Robbie, SJ; Buch, PK; Azam, SA; Bainbridge, JWB; Smith, AJ; (2011) Long-Term Preservation of Cones and Improvement in Visual Function Following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis Caused by Guanylate Cyclase-1 Deficiency. Human Gene Therapy , 22 (10) 1179 - 1190. 10.1089/hum.2011.069. Green open access
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2005

Pearson, R.A.; Lüneborg, N.L.; Becker, D.L.; Mobbs, P.; (2005) Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells. Journal of Neuroscience , 25 (46) pp. 10803-10814. 10.1523/JNEUROSCI.2312-05.2005. Green open access
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2002

Pearson, R; Catsicas, M; Becker, D; Mobbs, P; (2002) Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone. JOURNAL OF NEUROSCIENCE , 22 (17) pp. 7569-7579. Green open access
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This list was generated on Sun Mar 24 04:33:53 2024 GMT.