Browse by UCL people
Group by: Type | Date
Number of items: 29.
2022
Matsuyama, A;
Kalargyrou, AA;
Smith, AJ;
Ali, RR;
Pearson, RA;
(2022)
A comprehensive atlas of Aggrecan, Versican, Neurocan and Phosphacan expression across time in wildtype retina and in retinal degeneration.
Scientific Reports
, 12
, Article 7282. 10.1038/s41598-022-11204-w.
|
2021
Aghaizu, ND;
Warre-Cornish, KM;
Robinson, MR;
Ali, RR;
Pearson, RA;
(2021)
Tracking neuronal motility in live murine retinal explants.
STAR Protocols
, 2
(4)
, Article 101008. 10.1016/j.xpro.2021.101008.
|
Aghaizu, ND;
Warre-Cornish, KM;
Robinson, MR;
Waldron, PV;
Maswood, RN;
Smith, AJ;
Ali, RR;
(2021)
Repeated nuclear translocations underlie photoreceptor positioning and lamination of the outer nuclear layer in the mammalian retina.
Cell Reports
, 36
(5)
, Article 109461. 10.1016/j.celrep.2021.109461.
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Hippert, C;
Graca, AB;
Basche, M;
Kalargyrou, AA;
Georgiadis, A;
Ribeiro, J;
Matsuyama, A;
... Pearson, RA; + view all
(2021)
RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration.
Glia
10.1002/glia.24034.
(In press).
|
Kalargyrou, Aikaterini A;
Basche, Mark;
Hare, Aura;
West, Emma L;
Smith, Alexander J;
Ali, Robin R;
Pearson, Rachael A;
(2021)
Nanotube-like processes facilitate material transfer between photoreceptors.
EMBO Reports
, 22
, Article e53732. 10.15252/embr.202153732.
|
Ribeiro, J;
Procyk, CA;
West, EL;
O'Hara-Wright, M;
Martins, MF;
Khorasani, MM;
Hare, A;
... Ali, RR; + view all
(2021)
Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors.
Cell Reports
, 35
(3)
, Article 109022. 10.1016/j.celrep.2021.109022.
|
2020
Langhe, R;
Pearson, RA;
(2020)
Rebuilding the Retina: Prospects for Müller Glial-mediated Self-repair.
Current Eye Research
, 45
(3)
pp. 349-360.
10.1080/02713683.2019.1669665.
|
2019
Aldunate, EZ;
Di Foggia, V;
Di Marco, F;
Hervas, LA;
Ribeiro, JC;
Holder, DL;
Patel, A;
... Sowden, JC; + view all
(2019)
Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision.
Scientific Reports
, 9
, Article 2314. 10.1038/s41598-018-38294-9.
|
2018
Gonzalez Cordero, A;
Goh, D;
Kruczek, K;
Naeem, A;
Fernando, M;
Kleine Holthaus, S-M;
Takaaki, M;
... Ali, RR; + view all
(2018)
Assessment of AAV vector tropisms for mouse and human pluripotent stem cell-derived RPE and photoreceptor cells.
Human Gene Therapy
, 29
(10)
pp. 1124-1139.
10.1089/hum.2018.027.
|
Kleine Holthaus, S-M;
Ribeiro, J;
Abelleira-Hervas, L;
Pearson, RA;
Duran, Y;
Georgiadis, A;
Sampson, RD;
... Ali, RR; + view all
(2018)
Prevention of Photoreceptor Cell Loss in a Cln6nclf Mouse Model of Batten Disease Requires CLN6 Gene Transfer to Bipolar Cells.
Molecular Therapy
, 26
(5)
pp. 1343-1353.
10.1016/j.ymthe.2018.02.027.
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Pearson, RA;
Ali, RR;
(2018)
Unlocking the Potential for Endogenous Repair to Restore Sight.
Neuron
, 100
(3)
pp. 524-526.
10.1016/j.neuron.2018.10.035.
|
Waldron, PV;
Di Marco, F;
Kruczek, K;
Ribeiro, J;
Graca, AB;
Hippert, C;
Aghaizu, ND;
... Pearson, RA; + view all
(2018)
Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner.
Stem Cell Reports
10.1016/j.stemcr.2017.12.008.
|
2017
Aghaizu, ND;
Kruczek, K;
Gonzalez-Cordero, A;
Ali, RR;
Pearson, RA;
(2017)
Chapter 8 - Pluripotent stem cells and their utility in treating photoreceptor degenerations.
Progress in Brain Research
, 231
pp. 191-223.
10.1016/bs.pbr.2017.01.001.
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Gonzalez-Cordero, A;
Kruczek, K;
Naeem, A;
Fernando, M;
Kloc, M;
Ribeiro, J;
Goh, D;
... Ali, RR; + view all
(2017)
Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors.
Stem Cell Reports
10.1016/j.stemcr.2017.07.022.
(In press).
|
Graca, AB;
(2017)
Assessment and modulation of gliosis in inherited eye disease and its impact on cell replacement therapy.
Doctoral thesis , UCL (University College London).
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Kruczek, K;
Gonzalez-Cordero, A;
Goh, D;
Naeem, A;
Jonikas, M;
Blackford, SJI;
Kloc, M;
... Ali, RR; + view all
(2017)
Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration.
Stem Cell Reports
, 8
(6)
pp. 1659-1674.
10.1016/j.stemcr.2017.04.030.
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Ovando-Roche, P;
Georgiadis, A;
Smith, AJ;
Pearson, RA;
Ali, RR;
(2017)
Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration.
Current Stem Cell Reports
, 3
(2)
pp. 112-123.
10.1007/s40778-017-0078-4.
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2016
Aghaizu, ND;
(2016)
Mechanisms of rod photoreceptor motility in development and following transplantation.
Doctoral thesis , UCL (University College London).
|
Athanasiou, D;
Aguila, M;
Opefi, CA;
South, K;
Bellingham, J;
Bevilacqua, D;
Munro, PM;
... Cheetham, ME; + view all
(2016)
Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.
Human Molecular Genetics
, 26
(2)
pp. 305-319.
10.1093/hmg/ddw387.
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Pearson, RA;
Gonzalez-Cordero, A;
West, EL;
Ribeiro, JR;
Aghaizu, N;
Goh, D;
Sampson, RD;
... Ali, RR; + view all
(2016)
Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors.
Nature Communications
, 7
, Article 13029. 10.1038/ncomms13029.
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2015
Hippert, C;
Graca, AB;
Barber, AC;
West, EL;
Smith, AJ;
Ali, RR;
Pearson, RA;
(2015)
Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific.
PLoS One
, 10
(3)
, Article e0120415. 10.1371/journal.pone.0120415.
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Hippert, C;
Graca, AB;
Pearson, RA;
(2015)
Gliosis Can Impede Integration Following Photoreceptor Transplantation into the Diseased Retina.
In: Rickman, CB and LaVail, MM and Anderson, RE and Grimm, C and Hollyfield, J and Ash, J, (eds.)
Retinal Degenerative Diseases: Mechanisms and Experimental Therapy.
(pp. pp. 579-585).
Springer: Cham, Switzerland.
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Jayakody, SA;
Gonzalez-Cordero, A;
Ali, RR;
Pearson, RA;
(2015)
Cellular strategies for retinal repair by photoreceptor replacement.
Progress in Retinal and Eye Research
, 46
31 - 66.
10.1016/j.preteyeres.2015.01.003.
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Lakowski, J;
Gonzalez-Cordero, A;
West, EL;
Han, YT;
Welby, E;
Naeem, A;
Blackford, SJ;
... Sowden, JC; + view all
(2015)
Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell-Derived Self-Forming Retina.
Stem Cells
, 33
(8)
pp. 2469-2482.
10.1002/stem.2051.
|
2011
Buch, PK;
Mihelec, M;
Cottrill, P;
Wilkie, SE;
Pearson, RA;
Duran, Y;
West, EL;
... Hunt, DM; + view all
(2011)
Dominant Cone-Rod Dystrophy: A Mouse Model Generated by Gene Targeting of the GCAP1/Guca1a Gene.
PLOS ONE
, 6
(3)
, Article e18089. 10.1371/journal.pone.0018089.
|
Carvalho, LS;
Xu, JH;
Pearson, RA;
Smith, AJ;
Bainbridge, JW;
Morris, LM;
Fliesler, SJ;
... Ali, RR; + view all
(2011)
Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy.
Human Molecular Genetics
, 20
(16)
3161 - 3175.
10.1093/hmg/ddr218.
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Mihelec, M;
Pearson, RA;
Robbie, SJ;
Buch, PK;
Azam, SA;
Bainbridge, JWB;
Smith, AJ;
(2011)
Long-Term Preservation of Cones and Improvement in Visual Function Following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis Caused by Guanylate Cyclase-1 Deficiency.
Human Gene Therapy
, 22
(10)
1179 - 1190.
10.1089/hum.2011.069.
|
2005
Pearson, R.A.;
Lüneborg, N.L.;
Becker, D.L.;
Mobbs, P.;
(2005)
Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells.
Journal of Neuroscience
, 25
(46)
pp. 10803-10814.
10.1523/JNEUROSCI.2312-05.2005.
|
2002
Pearson, R;
Catsicas, M;
Becker, D;
Mobbs, P;
(2002)
Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone.
JOURNAL OF NEUROSCIENCE
, 22
(17)
pp. 7569-7579.
|