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Number of items: 78.

2018

Ferrari, R; Kia, DA; Tomkins, JE; Hardy, J; Wood, NW; Lovering, RC; Lewis, PA; (2018) Stratification of candidate genes for Parkinson's disease using weighted protein-protein interaction network analysis. BMC Genomics , 19 , Article 452. 10.1186/s12864-018-4804-9. Green open access
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Härtlova, A; Herbst, S; Peltier, J; Rodgers, A; Bilkei-Gorzo, O; Fearns, A; Dill, BD; ... Gutierrez, MG; + view all (2018) LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. The EMBO Journal , 2018 , Article e98694. 10.15252/embj.201798694. (In press). Green open access
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Lewis, PA; (2018) Mutations in LRRK2 amplify cell-to-cell protein aggregate propagation: a hypothesis. [Letter]. Acta Neuropathologica , 135 (6) pp. 973-976. 10.1007/s00401-018-1838-7. Green open access
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Manzoni, C; Kia, DA; Vandrovcova, J; Hardy, J; Wood, NW; Lewis, PA; Ferrari, R; (2018) Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences. Briefings in Bioinformatics , 19 (2) pp. 286-302. 10.1093/bib/bbw114. Green open access
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Manzoni, C; Mamais, A; Dihanich, S; Soutar, MPM; Plun-Favreau, H; Bandopadhyay, R; Abeti, R; ... Lewis, PA; + view all (2018) mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Bioscience Reports , 38 (2) , Article BSR20171669. 10.1042/BSR20171669. Green open access
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Price, A; Manzoni, C; Cookson, MR; Lewis, PA; (2018) The LRRK2 signalling system. Cell and Tissue Research 10.1007/s00441-017-2759-9. Green open access
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Tomkins, JE; Dihanich, S; Beilina, A; Ferrari, R; Ilacqua, N; Cookson, MR; Lewis, PA; (2018) Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins. Proteomics 10.1002/pmic.201700444. (In press). Green open access
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2017

Civiero, L; Cogo, S; Kiekens, A; Morganti, C; Tessari, I; Lobbestael, E; Baekelandt, V; ... Greggio, E; + view all (2017) PAK6 Phosphorylates 14-3-3 gamma to Regulate Steady State Phosphorylation of LRRK2. Frontiers in Molecular Neuroscience , 10 , Article 417. 10.3389/fnmol.2017.00417. Green open access
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Ferrari, R; Lovering, RC; Hardy, J; Lewis, PA; Manzoni, C; (2017) Weighted Protein Interaction Network Analysis of Frontotemporal Dementia. Journal of Proteome Research , 16 (2) pp. 999-1013. 10.1021/acs.jproteome.6b00934. Green open access
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Manzoni, C; Ferrari, R; Hardy, J; Lovering, RC; Bandopadhyay, R; Lewis, PA; (2017) Protein network analysis of FTD and PD: pathways and candidate genes for sporadic disease. Presented at: 118th Meeting of the British-Neuropathological-Society, Royal Coll Phys, London, ENGLAND.

Murthy, MN; Blauwendraat, C; UKBEC, ; Guelfi, S; IPDGC, ; Hardy, J; Lewis, PA; (2017) Increased brain expression of GPNMB is associated with genome wide significant risk for Parkinson's disease on chromosome 7p15.3. Neurogenetics 10.1007/s10048-017-0514-8. Green open access
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Noyce, AJ; Kia, DA; Hemani, G; Nicolas, A; Price, TR; De Pablo-Fernandez, E; Haycock, PC; ... Wood, NW; + view all (2017) Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study. PLoS Medicine , 14 (6) , Article e1002314. 10.1371/journal.pmed.1002314. Green open access
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2016

Kara, E; Tucci, A; Manzoni, C; Lynch, DS; Elpidorou, M; Bettencourt, C; Chelban, V; ... Houlden, H; + view all (2016) Genetic and phenotypic characterization of complex hereditary spastic paraplegia. Brain , 139 (7) pp. 1904-1918. 10.1093/brain/aww111. Green open access
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Lubbe, SJ; Escott-Price, V; Gibbs, JR; Nalls, MA; Bras, J; Price, TR; Nicolas, A; ... for International Parkinson’s Disease Genomics Consortium, .; + view all (2016) Additional rare variant analysis in Parkinson's disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance. Human Molecular Genetics , 25 (24) pp. 5483-5489. 10.1093/hmg/ddw348. Green open access
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Manzoni, C; Mamais, A; Roosen, DA; Dihanich, S; Soutar, MPM; Plun-Favreau, H; Bandopadhyay, R; ... Lewis, PA; + view all (2016) mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1. Scientific Reports , 6 , Article 35106. 10.1038/srep35106. Green open access
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2015

Civiero, L; Cirnaru, MD; Beilina, A; Rodella, U; Russo, I; Belluzzi, E; Lobbestael, E; ... Greggio, E; + view all (2015) Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. JOURNAL OF NEUROCHEMISTRY , 135 (6) pp. 1242-1256. 10.1111/jnc.13369.

Kiely, AP; Ling, H; Asi, YT; Kara, E; Proukakis, C; Schapira, AH; Morris, HR; ... Holton, JL; + view all (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. In: BIOMED CENTRAL LTD

Kiely, AP; Ling, H; Asi, YT; Kara, E; Proukakis, C; Schapira, AH; Morris, HR; ... Holton, JL; + view all (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. Molecular Neurodegeneration , 10 , Article 41. 10.1186/s13024-015-0038-3. Green open access
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Manzoni, C; Denny, P; Lovering, RC; Lewis, PA; (2015) Computational analysis of the LRRK2 interactome. PeerJ , 3 , Article e778. 10.7717/peerj.778. Green open access
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van der Brug, MP; Singleton, A; Gasser, T; Lewis, PA; (2015) Parkinson's disease: From human genetics to clinical trials. SCIENCE TRANSLATIONAL MEDICINE , 7 (305) 10.1126/scitranslmed.aaa8280.

2014

Civiero, L; Dihanich, S; Lewis, PA; Greggio, E; (2014) Genetic, Structural, and Molecular Insights into the Function of Ras of Complex Proteins Domains. CHEMISTRY & BIOLOGY , 21 (7) pp. 809-818. 10.1016/j.chembiol.2014.05.010.

Dihanich, S; Civiero, L; Manzoni, C; Mamais, A; Bandopadhyay, R; Greggio, E; Lewis, PA; (2014) GTP binding controls complex formation by the human ROCO protein MASL1. FEBS J , 281 (1) pp. 261-274. 10.1111/febs.12593. Green open access
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Mamais, A; Chia, R; Beilina, A; Hauser, DN; Hall, C; Lewis, PA; Cookson, MR; (2014) Arsenite Stress Downregulates Phosphorylation and 14-3-3 Binding of Leucine-rich Repeat Kinase 2 (LRRK2) Promoting Self-Association and Cellular Redistribution. J Biol Chem , 289 (31) pp. 21386-21400. 10.1074/jbc.M113.528463. Green open access
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Schulte, EC; Ellwanger, DC; Dihanich, S; Manzoni, C; Stangl, K; Schormair, B; Graf, E; ... Winkelmann, J; + view all (2014) Rare variants in LRRK1 and Parkinson's disease. NEUROGENETICS , 15 (1) pp. 49-57. 10.1007/s10048-013-0383-8.

Tsika, E; Glauser, L; Moser, R; Fiser, A; Daniel, G; Sheerin, UM; Lees, A; ... Moore, DJ; + view all (2014) Parkinson's Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration. Hum Mol Genet , 23 (17) pp. 4621-4638. 10.1093/hmg/ddu178. Green open access
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2013

Burchell, VS; Nelson, DE; Sanchez-Martinez, A; Delgado-Camprubi, M; Ivatt, RM; Pogson, JH; Randle, SJ; ... Plun-Favreau, H; + view all (2013) The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nature Neuroscience , 16 (9) pp. 1257-1265. 10.1038/nn.3489. Green open access
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Kara, E; Lewis, PA; Ling, H; Proukakis, C; Houlden, H; Hardy, J; (2013) α-Synuclein mutations cluster around a putative protein loop. Neuroscience Letters , 546 pp. 67-70. 10.1016/j.neulet.2013.04.058.

Kara, E; Lewis, PA; Ling, H; Proukakis, C; Houlden, H; Hardy, J; (2013) α-Synuclein mutations cluster around a putative protein loop. Neurosci Lett , 546 67 - 70. 10.1016/j.neulet.2013.04.058. Green open access
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Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; Proukakis, C; ... Holton, JL; + view all (2013) α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy? Acta Neuropathologica , 125 (5) 753 - 769. 10.1007/s00401-013-1096-7. Green open access
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Kiely, AP; Asi, YT; Ling, H; Lees, AJ; Hardy, J; Revesz, T; Holton, JL; ... Quinn, N; + view all (2013) A-synucleinopathy associated with G51D SNCA mutation: A link between Parkinson's disease and multiple system atrophy? Acta Neuropathologica , 125 (5) 753 - 769. 10.1007/s00401-013-1096-7. Green open access
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Mamais, A; Raja, M; Manzoni, C; Dihanich, S; Lees, A; Moore, D; Lewis, PA; (2013) Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases. Neurobiol Dis , 58 pp. 183-190. 10.1016/j.nbd.2013.05.017. Green open access
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Manzoni, C; Lewis, PA; (2013) Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies. The FASEB Journal , 27 (9) 3424 - 3429. 10.1096/fj.12-223842. Green open access
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Manzoni, C; Mamais, A; Dihanich, S; Abeti, R; Soutar, MP; Plun-Favreau, H; Giunti, P; ... Lewis, PA; + view all (2013) Inhibition of LRRK2 kinase activity stimulates macroautophagy. Biochim Biophys Acta , 1833 (12) pp. 2900-2910. 10.1016/j.bbamcr.2013.07.020. Green open access
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Manzoni, C; Mamais, A; Dihanich, S; McGoldrick, P; Devine, MJ; Zerle, J; Kara, E; ... Lewis, PA; + view all (2013) Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation. Biochemical and Biophysical Research Communications , 441 (4) pp. 862-866. 10.1016/j.bbrc.2013.10.159. Green open access
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Manzoni, C; Mamais, A; Dihanich, S; Tooze, S; Bandopadhyay, R; Lewis, PA; (2013) LRRK2 regulates autophagy. In: (Proceedings) 114th Meeting of the British-Neuropathological-Society / Symposium on Advances in Motor Neuron Diseases. (pp. p. 10). WILEY-BLACKWELL

Paisan-Ruiz, C; Lewis, PA; Singleton, AB; (2013) LRRK2: Cause, Risk, and Mechanism. JOURNAL OF PARKINSONS DISEASE , 3 (2) pp. 85-103. 10.3233/JPD-130192.

Trabzuni, D; Ryten, M; Emmett, W; Ramasamy, A; Lackner, KJ; Zeller, T; Walker, R; ... Plagnol, V; + view all (2013) Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 Locus. PLOS ONE , 8 (8) , Article e70724. 10.1371/journal.pone.0070724. Green open access
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2012

Devine, MJ; Kaganovich, A; Ryten, M; Mamais, A; Trabzuni, D; Manzoni, C; McGoldrick, P; ... Lewis, PA; + view all (2012) Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue. PLOS ONE , 7 (1) , Article e22489. 10.1371/annotation/c12e4f9e-5aae-424b-a69f-fddf16976dc5. Green open access
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Jebelli, JD; Dihanich, S; Civiero, L; Manzoni, C; Greggio, E; Lewis, PA; (2012) GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1. SCIENTIFIC REPORTS , 2 (ARTN 695) 10.1038/srep00695. Gold open access

Lewis, PA; (2012) Assaying the Kinase Activity of LRRK2 in vitro. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (59) 10.3791/3495. Gold open access

Lewis, PA; (2012) James Parkinson: The Man Behind the Shaking Palsy. JOURNAL OF PARKINSONS DISEASE , 2 (3) pp. 181-187. 10.3233/JPD-2012-012108.

Lewis, PA; Alessi, DR; (2012) Deciphering the function of leucine-rich repeat kinase 2 and targeting its dysfunction in disease. BIOCHEMICAL SOCIETY TRANSACTIONS , 40 pp. 1039-1041. 10.1042/BST20120178.

Lewis, PA; Cookson, MR; (2012) Gene expression in the Parkinson's disease brain. BRAIN RESEARCH BULLETIN , 88 (4) pp. 302-312. 10.1016/j.brainresbull.2011.11.016.

Lewis, PA; Manzoni, C; (2012) LRRK2 and Human Disease: A Complicated Question or a Question of Complexes? SCIENCE SIGNALING , 5 (207) 10.1126/scisignal.2002680.

Manzoni, C; Dihanich, S; Mamais, A; Cai, H; Bandopadhyay, R; Lewis, PA; (2012) LRRK2 and autophagy: Molecular targets for Parkinson's disease? In: (Proceedings) 16th International Congress of Parkinson's Disease and Movement Disorders. (pp. S489-S489). WILEY-BLACKWELL

Patani, R; Lewis, PA; Trabzuni, D; Puddifoot, CA; Wyllie, DJA; Walker, R; Smith, C; ... Ryten, M; + view all (2012) Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis. JOURNAL OF NEUROCHEMISTRY , 122 (4) pp. 738-751. 10.1111/j.1471-4159.2012.07825.x.

Wray, S; Self, M; NINDS Parkinson's Disease iPSC Consortium, ; NINDS Huntington's Disease iPSC Consortium, ; NINDS ALS iPSC Consortium, ; Lewis, PA; Taanman, JW; ... Hardy, J; + view all (2012) Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. PLOS One , 7 (8) , Article e43099. 10.1371/journal.pone.0043099. Green open access
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2011

Devine, MJ; Kaganovich, A; Ryten, M; Mamais, A; Trabzuni, D; Manzoni, C; McGoldrick, P; ... Lewis, PA; + view all (2011) Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue. PLOS ONE , 6 (7) , Article e22489. 10.1371/journal.pone.0022489. Green open access
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Devine, MJ; Ryten, M; Vodicka, P; Thomson, AJ; Burdon, T; Houlden, H; Cavaleri, F; ... Kunath, T; + view all (2011) Parkinson's disease induced pluripotent stem cells with triplication of the alpha-synuclein locus. NAT COMMUN , 2 , Article 440. 10.1038/ncomms1453. Gold open access

2010

Plun-Favreau, H; Lewis, PA; Hardy, J; Martins, LM; Wood, NW; (2010) Cancer and neurodegeneration: between the devil and the deep blue sea. PLoS Genetics , 6 (12) , Article e1001257. 10.1371/journal.pgen.1001257. Green open access
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Wray, S; Lewis, PA; (2010) A tangled web - tau and sporadic Parkinson's disease. Front Psychiatry , 1 150-. 10.3389/fpsyt.2010.00150.

2009

Hardy, J; Lewis, P; Revesz, T; Lees, A; Paisan-Ruiz, C; (2009) The genetics of Parkinson's syndromes: a critical review. CURR OPIN GENET DEV , 19 (3) 254 - 265. 10.1016/j.gde.2009.03.008.

Lewis, PA; (2009) The function of ROCO proteins in health and disease. BIOL CELL , 101 (3) 183 - 191. 10.1042/BC20080053.

Li, YC; Dunn, L; Greggio, E; Krumm, B; Jackson, GS; Cookson, MR; Lewis, PA; (2009) The R1441C mutation alters the folding properties of the ROC domain of LRRK2. BBA-MOL BASIS DIS , 1792 (12) 1194 - 1197. 10.1016/j.bbadis.2009.09.010.

2008

Camargos, S; Scholz, S; Simon-Sanchez, J; Paisan-Ruiz, C; Lewis, P; Hernandez, D; Ding, J; ... Singleton, AB; + view all (2008) DYT16, a novel young-onset dystonia-parkinson ism disorder: identification of a segregating mutation in the stress-response protein PRKRA. LANCET NEUROL , 7 (3) 207 - 215. 10.1016/S1474-4422(08)70022-X.

Camargos, S; Scholz, S; Simón-Sánchez, J; Paisán-Ruiz, C; Lewis, P; Hernandez, D; Ding, J; ... Singleton, AB; + view all (2008) DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA. The Lancet Neurology , 7 (3) pp. 207-215. 10.1016/S1474-4422(08)70022-X.

Cookson, MR; Greggio, E; Lewis, P; (2008) The Role of LRRK2 Kinase Activity in Cellular PD Models. In: Parkinson's Disease. (pp. 423-431).

Cookson, MR; Hardy, J; Lewis, PA; (2008) Genetic Neuropathology of Parkinson's Disease. INT J CLIN EXP PATHO , 1 (3) 217 - 231. Gold open access

Deng, JP; Lewis, PA; Greggio, E; Sluch, E; Beilina, A; Cookson, MR; (2008) Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase. P NATL ACAD SCI USA , 105 (5) 1499 - 1504. 10.1073/pnas.0709098105.

Devine, MJ; Lewis, PA; (2008) Emerging pathways in genetic Parkinson's disease: tangles, Lewy bodies and LRRK2. FEBS J , 275 (23) 5748 - 5757. 10.1111/j.1742-4658.2008.06707.x.

Greggio, E; Zambrano, I; Kaganovich, A; Beilina, A; Taymans, J-M; Daniels, V; Lewis, P; ... Cookson, MR; + view all (2008) The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. JOURNAL OF BIOLOGICAL CHEMISTRY , 283 (24) pp. 16906-16914. 10.1074/jbc.M708718200.

Lewis, PA; (2008) Emerging pathways in genetic Parkinson's disease. FEBS J , 275 (23) 5747 - 5747. 10.1111/j.1742-4658.2008.06706.x.

2007

Chandran, J; Lewis, P; (2007) Mad fly disease. JOURNAL OF NEUROSCIENCE , 27 (5) pp. 971-972. 10.1523/JNEUROSCI.5427-06.2007.

Greggio, E; Lewis, PA; van der Brug, MP; Ahmad, R; Kaganovich, A; Ding, JH; Beilina, A; ... Cookson, MR; + view all (2007) Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1. J NEUROCHEM , 102 (1) 93 - 102. 10.1111/j.1471-4159.2007.04523.x.

Hoe, H-S; Cooper, MJ; Burns, MP; Lewis, PA; van der Brug, M; Chakraborty, G; Cartagena, CM; ... Rebeck, GW; + view all (2007) The metalloprotease inhibitor TIMP-3 regulates amyloid precursor protein and apolipoprotein E receptor proteolysis. JOURNAL OF NEUROSCIENCE , 27 (40) pp. 10895-10905. 10.1523/JNEUROSCI.3135-07.2007.

Lewis, P.A.; Critchley, H.D.; Rotshtein, P.; Dolan, R.J.; (2007) Neural correlates of processing valence and arousal in affective words. Cerebral Cortex , 17 (3) pp. 742-748. 10.1093/cercor/bhk024. Green open access
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Lewis, PA; Greggio, E; Beilina, A; Jain, S; Baker, A; Cookson, MR; (2007) The R1441C mutation of LRRK2 disrupts GTP hydrolysis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , 357 (3) pp. 668-671. 10.1016/j.bbrc.2007.04.006.

2006

Greggio, E; Jain, S; Kingsbury, A; Bandopadhyay, R; Lewis, P; Kaganovich, A; van der Brug, MP; ... Cookson, MR; + view all (2006) Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. NEUROBIOL DIS , 23 (2) 329 - 341. 10.1016/j.nbd.2006.04.001.

Lewis, PA; Properzi, F; Prodromidou, K; Clarke, AR; Collinge, J; Jackson, GS; (2006) Removal of the glycosylphosphatidylinositol anchor from PrPSc by cathepsin D does not reduce prion infectivity. BIOCHEM J , 395 443 - 448. 10.1042/BJ20051677. Gold open access

Lewis, PA; Tattum, MH; Jones, S; Bhelt, D; Batchelor, M; Clarke, AR; Collinge, J; (2006) Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation. J GEN VIROL , 87 2443 - 2449. 10.1099/vir.0.81630-0.

2002

Amtul, Z; Lewis, PA; Piper, S; Crook, R; Baker, M; Findlay, K; Singleton, A; ... Golde, TE; + view all (2002) A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch. NEUROBIOLOGY OF DISEASE , 9 (2) pp. 269-273. 10.1006/nbdi.2001.0473.

Tang-Wai, D; Lewis, P; Boeve, B; Hutton, M; Golde, T; Baker, M; Hardy, J; ... Petersen, R; + view all (2002) Familial frontotemporal dementia associated with a novel presenilin-1 mutation. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 14 (1) pp. 13-21. 10.1159/000058328.

2001

Lewis, PA; Piper, S; Baker, M; Onstead, L; Murphy, MP; Hardy, J; Wang, R; ... Golde, TE; + view all (2001) Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE , 1537 (1) pp. 58-62. 10.1016/S0925-4439(01)00054-0.

Mudher, A; Chapman, S; Richardson, J; Asuni, A; Gibb, G; Pollard, C; Killick, R; ... Lovestone, S; + view all (2001) Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. JOURNAL OF NEUROSCIENCE , 21 (14) pp. 4987-4995.

2000

Houlden, H; Baker, M; McGowan, E; Lewis, P; Hutton, M; Crook, R; Wood, NW; ... Revesz, T; + view all (2000) Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. ANN NEUROL , 48 (5) 806 - 808.

Lewis, PA; Perez-Tur, J; Golde, TE; Hardy, J; (2000) The presenilin 1 C92S mutation increases A beta 42 production. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , 277 (1) pp. 261-263. 10.1006/bbrc.2000.3646.

McLendon, C; Xin, TP; Ziani-Cherif, C; Murphy, MP; Findlay, KA; Lewis, PA; Pinnix, I; ... Golde, TE; + view all (2000) Cell-free assays for gamma-secretase activity. FASEB JOURNAL , 14 (15) pp. 2383-2386.

Murphy, MP; Uljon, SN; Fraser, PE; Fauq, A; Lookingbill, HA; Findlay, KA; Smith, TE; ... Golde, TE; + view all (2000) Presenilin 1 regulates pharmacologically distinct gamma-secretase activities - Implications for the role of presenilin in gamma-secretase cleavage. JOURNAL OF BIOLOGICAL CHEMISTRY , 275 (34) pp. 26277-26284. 10.1074/jbc.M002812200. Gold open access

This list was generated on Sun Jul 15 06:12:21 2018 BST.