Browse by UCL people
Group by: Type | Date
Number of items: 22.
Article
Angelova, PR;
Choil, ML;
Berezhnov, A;
Horrocks, MH;
Hughes, CD;
De, S;
Rodrigues, M;
... Gandhi, S; + view all
(2020)
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation.
Cell Death & Differentiation
, 27
pp. 2781-2796.
10.1038/s41418-020-0542-z.
|
 |
|
Deas, E;
Cremades, N;
Angelova, PR;
Ludtmann, MHR;
Yao, Z;
Chen, S;
Horrocks, MH;
... Abramov, AY; + view all
(2016)
Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease.
Antioxidants & Redox Signaling
, 24
(7)
pp. 376-391.
10.1089/ars.2015.6343.
|
|
|
Devine, Michael J;
Szulc, Blanka R;
Howden, Jack H;
López-Doménech, Guillermo;
Ruiz, Arnaud;
Kittler, Josef T;
(2022)
Mitochondrial Ca²⁺ Uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses.
Journal of Cell Science
10.1242/jcs.259823.
(In press).
|
|
Devine, MJ;
Kaganovich, A;
Ryten, M;
Mamais, A;
Trabzuni, D;
Manzoni, C;
McGoldrick, P;
... Lewis, PA; + view all
(2012)
Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.
PLOS ONE
, 7
(1)
, Article e22489. 10.1371/annotation/c12e4f9e-5aae-424b-a69f-fddf16976dc5.
|
 |
|
Devine, MJ;
Kaganovich, A;
Ryten, M;
Mamais, A;
Trabzuni, D;
Manzoni, C;
McGoldrick, P;
... Lewis, PA; + view all
(2011)
Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.
PLOS ONE
, 6
(7)
, Article e22489. 10.1371/journal.pone.0022489.
|
|
|
Devine, MJ;
Kittler, JT;
(2018)
Mitochondria at the neuronal presynapse in health and disease.
[Review].
Nature Reviews Neuroscience
, 19
(2)
pp. 63-80.
10.1038/nrn.2017.170.
|
|
Horrocks, MH;
Lee, SF;
Gandhi, S;
Magdalinou, NK;
Chen, SW;
Devine, MJ;
Tosatto, L;
... Klenerman, D; + view all
(2016)
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids.
ACS Chemical Neuroscience
, 7
(3)
pp. 399-406.
10.1021/acschemneuro.5b00324.
|
|
Kriegsheim, AV;
McDonagh, K;
Sotthibundhu, A;
Garcia-Munoz, A;
Klawiter, A;
Thompson, K;
Chauhan, KD;
... Shen, S; + view all
(2016)
Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells.
Stem Cell Research & Therapy
, 7
, Article 166. 10.1186/s13287-016-0425-x.
|
|
Little, D;
Ketteler, R;
Gissen, P;
Devine, MJ;
(2019)
Using stem cell-derived neurons in drug screening for neurological diseases.
Neurobiology of Aging
, 78
pp. 130-141.
10.1016/j.neurobiolaging.2019.02.008.
|
|
Little, D;
Luft, C;
Mosaku, O;
Ketteler, R;
Devine, MJ;
Gissen, P;
(2019)
High-Content Analysis of Mitochondrial Function in iPSC-Derived Neurons.
Methods in Molecular Biology
, 1994
pp. 175-184.
10.1007/978-1-4939-9477-9_16.
|
|
Little, D;
Luft, C;
Mosaku, O;
Ketteler, R;
Devine, MJ;
Gissen, P;
(2019)
High-Content Autophagy Analysis in iPSC-Derived Neurons Using Immunofluorescence.
Methods in Molecular Biology
, 1994
pp. 165-174.
10.1007/978-1-4939-9477-9_15.
|
|
Little, D;
Luft, C;
Mosaku, O;
Lorvellec, M;
Yao, Z;
Paillusson, S;
Kriston-Vizi, J;
... Gissen, P; + view all
(2018)
A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA.
Scientific Reports
, 8
, Article 9033. 10.1038/s41598-018-27058-0.
|
|
|
Little, D;
Luft, C;
Pezzini-Picart, O;
Mosaku, O;
Ketteler, R;
Devine, MJ;
Gissen, P;
(2019)
Seeding Induced Pluripotent Stem Cell-Derived Neurons onto 384-Well Plates.
Methods in Molecular Biology
, 1994
pp. 159-164.
10.1007/978-1-4939-9477-9_14.
|
|
Ludtmann, MHR;
Angelova, PR;
Horrocks, MH;
Choi, ML;
Rodrigues, M;
Baev, AY;
Berezhnov, AV;
... Gandhi, S; + view all
(2018)
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.
Nature Communications
, 9
, Article 2293. 10.1038/s41467-018-04422-2.
|
|
|
Manzoni, C;
Mamais, A;
Dihanich, S;
McGoldrick, P;
Devine, MJ;
Zerle, J;
Kara, E;
... Lewis, PA; + view all
(2013)
Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation.
Biochemical and Biophysical Research Communications
, 441
(4)
pp. 862-866.
10.1016/j.bbrc.2013.10.159.
|
|
|
Nadappuram, BP;
Cadinu, P;
Barik, A;
Ainscough, AJ;
Devine, MJ;
Kang, M;
Gonzalez-Garcia, J;
... Edel, JB; + view all
(2019)
Nanoscale tweezers for single-cell biopsies.
Nature Nanotechnology
, 14
pp. 80-88.
10.1038/s41565-018-0315-8.
|
|
Ofrim, Marisa;
Little, Daniel;
Nazari, Mina;
Minnis, Christopher J;
Devine, Michael J;
Mole, Sara E;
Gissen, Paul;
(2023)
Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations.
Stem Cell Research
, 74
, Article 103291. 10.1016/j.scr.2023.103291.
|
|
Paillusson, S;
Gomez-Suaga, P;
Stoica, R;
Little, D;
Gissen, P;
Devine, MJ;
Noble, W;
... Miller, CCJ; + view all
(2017)
α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca(2+) homeostasis and mitochondrial ATP production.
Acta Neuropathol
10.1007/s00401-017-1704-z.
(In press).
|
|
Sposito, T;
Preza, E;
Mahoney, CJ;
Setó-Salvia, N;
Ryan, NS;
Morris, HR;
Arber, C;
... Wray, S; + view all
(2015)
Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT.
Human Molecular Genetics
, 24
(18)
pp. 5260-5269.
10.1093/hmg/ddv246.
|
|
Vaccaro, V;
Devine, MJ;
Higgs, NF;
Kittler, JT;
(2017)
Miro1-dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity.
EMBO Reports
, 18
(2)
pp. 231-240.
10.15252/embr.201642710.
|
|
|
Wray, S;
Self, M;
NINDS Parkinson's Disease iPSC Consortium;
NINDS Huntington's Disease iPSC Consortium;
NINDS ALS iPSC Consortium;
Lewis, PA;
Taanman, JW;
... Hardy, J; + view all
(2012)
Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.
PLOS One
, 7
(8)
, Article e43099. 10.1371/journal.pone.0043099.
|
|
Thesis
|
Devine, MJ;
(2012)
Patient-derived cell models of Parkinson’s disease.
Doctoral thesis , UCL (University College London).
|
|
