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Article

Abbruzzese, G; Agid, Y; Albanese, A; Alf, C; Allen, R; Amar, K; ... Zifko, U; + view all (2001) An open letter to the Committee on the Nobel Prize in Medicine. PARKINSONISM & RELATED DISORDERS , 7 (2) 149 - 155.

Abraham, R; Myers, A; Wavrant-DeVrieze, F; Hamshere, ML; Thomas, HV; Marshall, H; ... Jones, L; + view all (2001) Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. HUMAN GENETICS , 109 (6) 646 - 652. 10.1007/s00439-001-0614-1.

Adighibe, O; Arepalli, S; Duckworth, J; Hardy, J; Wavrant-De Vrieze, F; (2006) Genetic variability at the LXR gene (NR1H2) may contribute to the risk of Alzheimer's disease. NEUROBIOLOGY OF AGING , 27 (10) 1431 - 1434. 10.1016/j.neurobiolaging.2005.08.010.

Adlkofer, F; Aguzzi, A; Baumeister, R; Haass, C; Silva, ODE; DeStrooper, B; ... Wiltfang, J; + view all (2002) Early diagnosis of Alzheimer's disease and related dementia (DIADEM) - A research network funded by the European Union. NEUROBIOL AGING , 23 (1) S383 - S383.

ADROER, R; LOPEZACEDO, C; OLIVA, R; HARDY, J; FIDANI, L; (1993) A NOVEL SILENT VARIANT AT CODON-711 AND A VARIANT AT CODON-708 OF THE APP SEQUENCE DETECTED IN SPANISH ALZHEIMER AND CONTROL CASES. NEUROSCIENCE LETTERS , 150 (1) 33 - 34. 10.1016/0304-3940(93)90101-P.

Aggarwal, A; Schneider, SA; Houlden, H; Silverdale, M; Paudel, R; Paisan-Ruiz, C; ... Bhatt, M; + view all (2010) Indian-Subcontinent NBIA: Unusual Phenotypes, Novel PANK2 Mutations, and Undetermined Genetic Forms. MOVEMENT DISORD , 25 (10) 1424 - 1431. 10.1002/mds.23095.

Ahmed, R; Guerreiro, R; Rohrer, JD; Guven, G; Rossor, MN; Hardy, J; Fox, NC; (2013) A novel A781V mutation in the CSF1R gene causes hereditary diffuse leucoencephalopathy with axonal spheroids. Journal of the Neurological Sciences , 332 (1-2) pp. 141-144. 10.1016/j.jns.2013.06.007. Green and gold open access
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ALMQVIST, P; CARLSSON, S; HARDY, J; WINBLAD, B; (1986) REGIONAL AND SUBCELLULAR-DISTRIBUTION OF THY-1 IN HUMAN-BRAIN ASSAYED BY A SOLID-PHASE RADIOIMMUNOASSAY. JOURNAL OF NEUROCHEMISTRY , 46 (3) 681 - 685. 10.1111/j.1471-4159.1986.tb13025.x.

Amtul, Z; Lewis, PA; Piper, S; Crook, R; Baker, M; Findlay, K; ... Golde, TE; + view all (2002) A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch. Neurobiol Dis , 9 (2) 269 - 273. 10.1006/nbdi.2001.0473.

Andreasson, U; Lautner, R; Mattsson, N; Wallin, A; Blennow, K; Zetterberg, H; ... Hampel, H; + view all (2014) CSF biomarkers for Alzheimer's pathology and the effect size of APOE ε4. Molecular Psychiatry , 19 (2) 148 - 149. 10.1038/mp.2013.18.

Andreasson, U; Lautner, R; Schott, JM; Mattsson, N; Hansson, O; Herukka, SK; ... Zetterberg, H; + view all (2014) CSF biomarkers for Alzheimer's pathology and the effect size of APOE ɛ4. Mol Psychiatry , 19 (2) 148 - 149. 10.1038/mp.2013.18.

Angeli, A; Mencacci, NE; Duran, R; Aviles-Olmos, I; Kefalopoulou, Z; Candelario, J; ... Foltynie, T; + view all (2013) Genotype and phenotype in Parkinson's disease: Lessons in heterogeneity from deep brain stimulation. Movement Disorders , 28 (10) pp. 1370-1375. 10.1002/mds.25535. Green and gold open access
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Antonarakis, SE; Chakravarti, A; Cohen, JC; Hardy, J; (2010) Mendelian disorders and multifactorial traits: the big divide or one for all? NAT REV GENET , 11 (5) 380 - 384. 10.1038/nrg2793.

Baker, M; Graff-Radford, D; DeVrieze, FW; Graff-Radford, N; Petersen, RC; Kokmen, E; ... Perez-Tur, J; + view all (2000) No association between TAU haplotype and Alzheimer's disease in population or clinic based series or in familial disease. NEUROSCIENCE LETTERS , 285 (2) 147 - 149. 10.1016/S0304-3940(00)01057-0.

Baker, M; Kwok, JBJ; Kucera, S; Crook, R; Farrer, M; Houlden, H; ... Hutton, M; + view all (1997) Localization of frontotemporal dementia with parkinsonism in an Australian kindred to chromosome 17q21-22. ANN NEUROL , 42 (5) 794 - 798.

Baker, M; Litvan, I; Houlden, H; Adamson, J; Dickson, D; Perez-Tur, J; ... Hutton, M; + view all (1999) Association of an extended haplotype in the tau gene with progressive supranuclear palsy. HUM MOL GENET , 8 (4) 711 - 715.

Balazs, R; Vernon, J; Hardy, J; (2011) Epigenetic mechanisms in Alzheimer's disease: progress but much to do. NEUROBIOL AGING , 32 (7) 1181 - 1187. 10.1016/j.neurobiolaging.2011.02.024.

Bandopadhyay, R; Kingsbury, AE; Cookson, MR; Reid, AR; Evans, IM; Hope, AD; ... Lees, AJ; + view all (2004) The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. BRAIN , 127 420 - 430. 10.1093/brain/awh054.

Baptista, MJ; O'Farrell, C; Daya, S; Ahmad, R; Miller, DW; Hardy, J; ... Cookson, MR; + view all (2003) Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines. JOURNAL OF NEUROCHEMISTRY , 85 (4) 957 - 968. 10.1046/j.1471-4159.2003.01742.x.

Baptista, MJ; O'Farrell, C; Hardy, J; Cookson, MR; (2003) Microarray analysis reveals induction of heat shock proteins mRNAs by the torsion dystonia protein, TorsinA. NEUROSCIENCE LETTERS , 343 (1) 5 - 8. 10.1016/S0304-3940(03)00302-1.

Bartolome, F; Wu, H-C; Burchell, VS; Preza, E; Wray, S; Houlden, H; ... Mandrioli, J; + view all (2013) Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels. Neuron , 78 (1) 57 - 64. 10.1016/j.neuron.2013.02.028.

Bartolome, F; Wu, HC; Burchell, VS; Preza, E; Wray, S; Mahoney, CJ; ... Plun-Favreau, H; + view all (2013) Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels. Neuron , 78 (1) 57 - 64. 10.1016/j.neuron.2013.02.028. Green and gold open access
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BARTON, A; HARDY, J; (1987) STABILITY OF BRAIN-RNA POSTMORTEM - EFFECT OF ALZHEIMERS-DISEASE. BIOCHEMICAL SOCIETY TRANSACTIONS , 15 (3) 558 - 559.

BARTON, A; HARRISON, P; NAJLERAHIM, A; HEFFERNAN, J; MCDONALD, B; ROBINSON, J; ... PEARSON, R; + view all (1990) INCREASED TAU-MESSENGER RNA IN ALZHEIMERS-DISEASE HIPPOCAMPUS. AMERICAN JOURNAL OF PATHOLOGY , 137 (3) 497 - 502.

Barton, AJL; Crook, BW; Karran, EH; Brown, F; Dewar, D; Mann, DMA; ... Roberts, GW; + view all (1996) Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease. NEURODEGENERATION , 5 (3) 213 - 218. 10.1006/neur.1996.0029.

Baum, AE; Akula, N; Cabanero, M; Cardona, I; Corona, W; Klemens, B; ... Bipolar, NIMHGI; + view all (2008) A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. MOLECULAR PSYCHIATRY , 13 (2) 197 - 207. 10.1038/sj.mp.4002012.

Beck, J; Pittman, A; Adamson, G; Campbell, T; Kenny, J; Houlden, H; ... Mead, S; + view all (2013) Validation of next-generation sequencing technologies in genetic diagnosis of dementia. Neurobiol Aging 10.1016/j.neurobiolaging.2013.07.017.

Beck, J; Poulter, M; Hensman, D; Rohrer, JD; Mahoney, CJ; Adamson, G; ... Mead, S; + view all (2013) Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population. Am J Hum Genet , 92 (3) 345 - 353. 10.1016/j.ajhg.2013.01.011.

Beck, J; Poulter, M; Hensman, D; Rohrer, JD; Mahoney, CJ; Adamson, G; ... Mead, S; + view all (2013) Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population. Am J Hum Genet , 92 (3) 345 - 353. 10.1016/j.ajhg.2013.01.011.

Beecham, GW; Hamilton, K; Naj, AC; Martin, ER; Huentelman, M; Myers, AJ; ... Montine, TJ; + view all (2014) Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias. PLoS Genetics , 10 (9) , Article e1004606. 10.1371/journal.pgen.1004606. Green and gold open access
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Beilina, A; Rudenko, IN; Kaganovich, A; Civiero, L; Chau, H; Kalia, SK; ... Cookson, MR; + view all (2014) Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. Proc Natl Acad Sci U S A , 111 (7) 2626 - 2631. 10.1073/pnas.1318306111.

Benitez, BA; Jin, SC; Guerreiro, R; Graham, R; Lord, J; Harold, D; ... Cruchaga, C; + view all (2013) Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol Aging 10.1016/j.neurobiolaging.2013.12.010.

Benitez, BA; Jin, SC; Harari, O; Bertelsen, S; Goate, AM; Cruchaga, C; ... Amouyel, P; + view all (2014) Missense variant in TREML2 protects against Alzheimer's disease. Neurobiology of Aging , 35 (6) 10.1016/j.neurobiolaging.2013.12.010.

Benitez, BA; Jin, SC; Harari, O; Bertelsen, S; Goate, AM; Cruchaga, C; ... Amouyel, P; + view all (2014) Missense variant in TREML2 protects against Alzheimer's disease. Neurobiology of Aging , 35 (6) 10.1016/j.neurobiolaging.2013.12.010.

Berg, D; Gasser, T; Postuma, RB; Bloem, B; Chan, P; Dubois, B; ... Deuschl, G; + view all (2014) Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease. Movement Disorders , 29 (4) 454 - 462. 10.1002/mds.25844.

Berg, D; Postuma, RB; Bloem, B; Chan, P; Dubois, B; Gasser, T; ... Deuschl, G; + view all (2014) Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease. MOVEMENT DISORDERS , 29 (4) 454 - 462. 10.1002/mds.25844.

Bettencourt, C; Morris, HR; Singleton, AB; Hardy, J; Houlden, H; (2013) Exome sequencing expands the mutational spectrum of SPG8 in a family with spasticity responsive to L-DOPA treatment. Journal of Neurology , 260 (9) pp. 2414-2416. 10.1007/s00415-013-7044-6. Green and gold open access
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Bettencourt, C; Morris, HR; Singleton, AB; Hardy, J; Houlden, H; (2013) Exome sequencing expands the mutational spectrum of SPG8 in a family with spasticity responsive to L-DOPA treatment. J Neurol 10.1007/s00415-013-7044-6.

Bettencourt, C; Ryten, M; Forabosco, P; Schorge, S; Hersheson, J; Hardy, J; ... for the United Kingdom Brain Expression Consortium,; + view all (2014) Insights From Cerebellar Transcriptomic Analysis Into the Pathogenesis of Ataxia. JAMA Neurol 10.1001/jamaneurol.2014.756.

Blennow, K; Hardy, J; Zetterberg, H; (2012) The neuropathology and neurobiology of traumatic brain injury. Neuron , 76 (5) 886 - 899. 10.1016/j.neuron.2012.11.021.

Blom, ES; Giedraitis, V; Arepalli, S; Hamshere, ML; Adighibe, O; Goate, A; ... Glaser, A; + view all (2009) Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs. BMC MEDICAL GENETICS , 10 , Article ARTN 122. 10.1186/1471-2350-10-122. Gold open access

Blom, ES; Holmans, P; Arepalli, S; Adighibe, O; Hamshere, ML; Gatz, M; ... Glaser, A; + view all (2008) Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS , 147B (6) 778 - 783. 10.1002/ajmg.b.30681.

Bobb, AJ; Addington, AM; Sidransky, E; Gornick, MC; Lerch, JP; Greenstein, DK; ... Rapoport, JL; + view all (2005) Support for association between ADHD and two candidate genes: NET1 and DRD1. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS , 134B (1) 67 - 72. 10.1002/ajmg.b.30142.

Boeve, BF; Maraganore, DM; Parisi, JE; Ivnik, RJ; Westmoreland, BF; Dickson, DW; ... Petersen, RC; + view all (2002) Corticobasal degeneration and frontotemporal dementia presentations in a kindred with nonspecific histopathology. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS , 13 (2) 80 - 90. 10.1159/000048638.

Boutoleau-Bretonnière, C; Camuzat, A; Le Ber, I; Bouya-Ahmed, K; Guerreiro, R; Deruet, AL; ... Vercelletto, M; + view all (2014) A Phenotype of Atypical Apraxia of Speech in a Family Carrying SQSTM1 Mutation. J Alzheimers Dis 10.3233/JAD-141512.

BRADFORD, H; FOLEY, P; DOCHERTY, M; FILLIT, H; LUINE, V; MCEWEN, B; ... HARDY, J; + view all (1989) ANTIBODIES IN SERUM OF PATIENTS WITH ALZHEIMERS-DISEASE CAUSE IMMUNOLYSIS OF CHOLINERGIC NERVE-TERMINALS FROM THE RAT CEREBRAL-CORTEX. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES , 16 (4) 528 - 534.

Bras, J; Guerreiro, R; Darwent, L; Parkkinen, L; Ansorge, O; Escott-Price, V; ... Hardy, J; + view all (2014) Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of Dementia with Lewy Bodies. Hum Mol Genet 10.1093/hmg/ddu334.

Bras, J; Guerreiro, R; Hardy, J; (2012) Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease. Nat Rev Neurosci , 13 (7) 453 - 464. 10.1038/nrn3271.

Bras, J; Guerreiro, R; Ribeiro, M; Morgadinho, A; Januario, C; Dias, M; ... Singleton, A; + view all (2008) Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2. BMC Neurology , 8 , Article 1. 10.1186/1471-2377-8-1. Green and gold open access
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Bras, J; Singleton, A; Cookson, MR; Hardy, J; (2008) Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease. FEBS J , 275 (23) 5767 - 5773. 10.1111/j.1742-4658.2008.06709.x.

Bras, JM; Guerreiro, RJ; Ribeiro, MH; Januario, C; Morgadinho, A; Oliveira, CR; ... Singleton, A; + view all (2005) G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort. MOVEMENT DISORD , 20 (12) 1653 - 1655.

Brown, AM; Gordon, D; Lee, H; Caudy, M; Hardy, J; Haroutunian, V; Blass, JP; (2004) Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS , 131B (1) 60 - 66. 10.1002/ajmg.b.30008.

Brown, AM; Gordon, D; Lee, H; Vrieze, FW-D; Cellini, E; Bagnoli, S; ... Blass, JP; + view all (2007) Testing for linkage and association across the dihydrolipoyl dehydrogenase gene region with Alzheimer's disease in three sample populations. NEUROCHEMICAL RESEARCH , 32 (4-5) 857 - 869. 10.1007/s11064-006-9235-3.

BROWN, J; ASHWORTH, A; GYDESEN, S; SORENSEN, A; ROSSOR, M; HARDY, J; COLLINGE, J; (1995) FAMILIAL NONSPECIFIC DEMENTIA MAPS TO CHROMOSOME-3. HUM MOL GENET , 4 (9) 1625 - 1628.

BROWN, J; GYDESEN, S; SORENSEN, SA; BRUN, A; DUFF, K; HOULDEN, H; ... HARDY, J; + view all (1993) EXCLUSION MAPPING IN FAMILIAL NONSPECIFIC DEMENTIA. DEMENTIA , 4 (3-4) 163 - 166.

BROWN, J; GYDESEN, S; SORENSEN, SA; BRUN, A; SMITH, S; HOULDEN, H; ... HARDY, J; + view all (1993) GENETIC-CHARACTERIZATION OF A FAMILIAL NONSPECIFIC DEMENTIA ORIGINATING IN JUTLAND, DENMARK. J NEUROL SCI , 114 (2) 138 - 143.

Bruni, AC; Momeni, P; Bernardi, L; Tomaino, C; Frangipane, F; Elder, J; ... Rogaeva, E; + view all (2007) Heterogeneity within a large kindred with frontotemporal dementia - A novel progranulin mutation. NEUROLOGY , 69 (2) 140 - 147. 10.1212/01.wnl.0000265220.64396.b4.

Burchell, VS; Delgado-Camprubi, M; Wray, S; Lewis, PA; Houlden, H; Abramov, AY; ... Whitworth, AJ; + view all (2013) The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nature Neuroscience , 16 (9) 1257 - 1265. 10.1038/nn.3489.

Burchell, VS; Nelson, DE; Sanchez-Martinez, A; Delgado-Camprubi, M; Ivatt, RM; Pogson, JH; ... Plun-Favreau, H; + view all (2013) The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nat Neurosci 10.1038/nn.3489.

Busby, J; O'Brien, KK; Gibson, AM; McKeith, IG; Perry, RH; Hardy, JA; ... Morris, CM; + view all (2004) Dementia with Lewy bodies: no association of polymorphisms in the human synphilin gene. NEUROGENETICS , 5 (4) 251 - 252. 10.1007/s10048-004-0188-x.

Busby, V; Goossens, S; Nowotny, P; Hamilton, G; Smemo, S; Harold, D; ... Lovestone, S; + view all (2004) alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease. NEUROMOLECULAR MEDICINE , 5 (2) 133 - 146. 10.1385/NMM:5:2:133.

Camargos, S; Scholz, S; Simón-Sánchez, J; Paisán-Ruiz, C; Lewis, P; Hernandez, D; ... Oliveira, CR; + view all (2008) DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA. The Lancet Neurology , 7 (3) 207 - 215. 10.1016/S1474-4422(08)70022-X.

Camargos, S; Scholz, S; Simon-Sanchez, J; Paisan-Ruiz, C; Lewis, P; Hernandez, D; ... Singleton, AB; + view all (2008) DYT16, a novel young-onset dystonia-parkinson ism disorder: identification of a segregating mutation in the stress-response protein PRKRA. LANCET NEUROL , 7 (3) 207 - 215. 10.1016/S1474-4422(08)70022-X.

Camargos, ST; Cardoso, F; Momeni, P; Gianetti, JG; Lees, A; Hardy, J; Singleton, A; (2008) Novel GCH1 mutation in a Brazilian family with dopa-responsive dystonia. MOVEMENT DISORD , 23 (2) 299 - 302. 10.1002/mds.21842.

Camargos, ST; Dornas, LO; Momeni, P; Lees, A; Hardy, J; Singleton, A; Cardoso, F; (2009) Familial Parkinsonism and Early Onset Parkinson's Disease in a Brazilian Movement Disorders Clinic: Phenotypic Characterization and Frequency of SNCA, PRKN, PINK1, and LRRK2 Mutations. MOVEMENT DISORD , 24 (5) 662 - 666. 10.1002/mds.22365.

Camargos, ST; Gurgel-Giannetti, J; Lees, A; Hardy, J; Singleton, A; Cardoso, F; (2011) Low prevalence of PANK2 mutations in Brazilian patients with early onset generalised dystonia and basal ganglia abnormalities on MRI. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 82 (9) 1059 - +. 10.1136/jnnp.2009.200808.

Casas, JP; Hingorani, AD; (2012) The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet , 379 (9822) 1214 - 1224. 10.1016/S0140-6736(12)60110-X. Green and gold open access
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Caselli, RJ; Hentz, JG; Osborne, D; Graff-Radford, NR; Barbieri, CJ; Alexander, GE; ... Saunders, AM; + view all (2002) Apolipoprotein E and intellectual achievement. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY , 50 (1) 49 - 54. 10.1046/j.1532-5415.2002.50007.x.

Caselli, RJ; Osborne, D; Reiman, EM; Hentz, JG; Barbieri, CJ; Saunders, AM; ... Alexander, GE; + view all (2001) Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study. JOURNAL OF THE NEUROLOGICAL SCIENCES , 189 (1-2) 93 - 98. 10.1016/S0022-510X(01)00577-9.

Chang, C-W; Hsu, W-C; Wu, Y-R; Fung, H-C; Pittman, A; Hardy, J; Structural study of the microtubule-associated protein tau locus of Alzheimer′s disease in Taiwan. Biomedical Journal , 37 (3) 127 - 132. 10.4103/2319-4170.117891. Gold open access

Charlesworth, G; Gandhi, S; Bras, JM; Barker, RA; Burn, DJ; Chinnery, PF; ... Wood, NW; + view all (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. Neurobiol Aging , 33 (4) 838.e7 - 838.11. 10.1016/j.neurobiolaging.2011.11.001.

Charlesworth, G; Gandhi, S; Bras, JM; Guerreiro, R; Hardy, J; Sheerin, U-M; ... Morris, H; + view all (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. Neurobiology of Aging , 33 (4) 10.1016/j.neurobiolaging.2011.11.001.

CHARTIER-HARLIN, M; CRAWFORD, F; PERL, D; STEELE, J; HARDY, J; (1993) SEQUENCING OF EXON-16 AND EXON-17 OF THE BETA-AMYLOID PRECURSOR PROTEIN GENE REVEALS THE BETA-AMYLOID SEQUENCE TO BE NORMAL IN CASES OF THE PARKINSON DEMENTIA COMPLEX OF GUAM. JOURNAL OF NEURAL TRANSMISSION-PARKINSONS DISEASE AND DEMENTIA SECTION , 5 (1) 63 - 65. 10.1007/BF02260915.

CHARTIERHARLIN, M; CRAWFORD, F; HAMANDI, K; MULLAN, M; GOATE, A; HARDY, J; ... VAN BROECKHOVEN, C; + view all (1991) SCREENING FOR THE BETA-AMYLOID PRECURSOR PROTEIN MUTATION (APP717-VAL-]ILE) IN EXTENDED PEDIGREES WITH EARLY ONSET ALZHEIMERS-DISEASE. NEUROSCIENCE LETTERS , 129 (1) 134 - 135. 10.1016/0304-3940(91)90738-F.

CHARTIERHARLIN, MC; CRAWFORD, F; HOULDEN, H; WARREN, A; HUGHES, D; FIDANI, L; ... MULLAN, M; + view all (1991) EARLY-ONSET ALZHEIMERS-DISEASE CAUSED BY MUTATIONS AT CODON-717 OF THE BETA-AMYLOID PRECURSOR PROTEIN GENE. NATURE , 353 (6347) 844 - 846.

Chibnik, LB; Shulman, JM; Leurgans, SE; Schneider, JA; Wilson, RS; Tran, D; ... De Jager, PL; + view all (2011) CR1 Is Associated with Amyloid Plaque Burden and Age-Related Cognitive Decline. ANN NEUROL , 69 (3) 560 - 569. 10.1002/ana.22277.

Chio, A; Schymick, JC; Restagno, G; Scholz, SW; Lombardo, F; Lai, SL; ... Traynor, BJ; + view all (2009) A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. HUM MOL GENET , 18 (8) 1524 - 1532. 10.1093/hmg/ddp059.

Choi, P; Golts, N; Snyder, H; Chong, M; Petrucelli, L; Hardy, J; ... Wolozin, B; + view all (2001) Co-association of parkin and alpha-synuclein. NEUROREPORT , 12 (13) 2839 - 2843. 10.1097/00001756-200109170-00017.

Clarimon, J; Asgeirsson, H; Singleton, A; Jakobsson, F; Hjaltason, H; Hardy, J; Sveinbjornsdottir, S; (2005) Torsin A haplotype predisposes to idiopathic dystonia. ANNALS OF NEUROLOGY , 57 (5) 765 - 767. 10.1002/ana.20485.

Clarimon, J; Djaldetti, R; Lleo, A; Guerreiro, RJ; Molinuevo, JL; Paisan-Ruiz, C; ... Hardy, J; + view all (2009) Whole genome analysis in a consanguineous family with early onset Alzheimer's disease. Neurobiology of Aging , 30 (12) 1986 - 1991. 10.1016/j.neurobiolaging.2008.02.008.

Clarimon, J; Djaldetti, R; Lleo, A; Guerreiro, RJ; Molinuevo, JL; Paisan-Ruiz, C; ... Hardy, J; + view all (2009) Whole genome analysis in a consanguineous family with early onset Alzheimer's disease. NEUROBIOL AGING , 30 (12) 1986 - 1991. 10.1016/j.neurobiolaging.2008.02.008.

Clarimon, J; Johnson, J; Dogu, O; Horta, W; Khan, N; Lees, AJ; ... Singleton, A; + view all (2005) Defining the ends of Parkin Exon 4 deletions in two different families with Parkinson's disease. AM J MED GENET B , 133B (1) 120 - 123. 10.1002/ajmg.b.30119.

Clarimon, J; Scholz, S; Fung, HC; Hardy, J; Eerola, J; Hellstrom, O; ... Singleton, A; + view all (2006) Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease. AMERICAN JOURNAL OF HUMAN GENETICS , 78 (6) 1082 - 1084. 10.1086/504727.

Clark, LN; Afridi, S; Mejia-Santana, H; Harris, J; Louis, ED; Cote, LJ; ... Marder, K; + view all (2004) Analysis of an early-onset Parkinson's disease cohort for DJ-1 mutations. MOVEMENT DISORDERS , 19 (7) 796 - 800. 10.1002/mds.20131.

CLARK, RF; HUTTON, M; FULDNER, RA; FROELICH, S; KARRAN, E; TALBOT, C; ... GOATE, A; + view all (1995) THE STRUCTURE OF THE PRESENILIN-1 (S182) GENE AND IDENTIFICATION OF 6 NOVEL MUTATIONS IN EARLY-ONSET AD FAMILIES. NAT GENET , 11 (2) 219 - 222.

Cleeter, MW; Chau, KY; Gluck, C; Mehta, A; Hughes, DA; Duchen, M; ... Schapira, AH; + view all (2013) Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage. Neurochem Int , 62 (1) 1 - 7. 10.1016/j.neuint.2012.10.010. Gold open access

Coleman, P; Kurlan, R; Crook, R; Werner, J; Hardy, J; (2004) New presenilin Alzheimer's disease case confirms the helical alignment of pathogenic mutations in transmembrane domain 5. NEUROSCIENCE LETTERS , 364 (3) 139 - 140. 10.1016/j.neulet.2004.04.030.

COLLINGE, J; BROWN, J; HARDY, J; MULLAN, M; ROSSOR, MN; BAKER, H; ... LANTOS, PL; + view all (1992) INHERITED PRION DISEASE WITH 144 BASE PAIR GENE INSERTION .2. CLINICAL AND PATHOLOGICAL FEATURES. BRAIN , 115 687 - 710.

COLLINGE, J; OWEN, F; POULTER, M; LEACH, M; CROW, TJ; ROSSOR, MN; ... LANTOS, PL; + view all (1990) PRION DEMENTIA WITHOUT CHARACTERISTIC PATHOLOGY. LANCET , 336 (8706) 7 - 9.

COLLINGE, J; PALMER, MS; SIDLE, KCL; MAHAL, SP; CAMPBELL, T; BROWN, J; ... GROEN, JJ; + view all (1994) FAMILIAL PICKS-DISEASE AND DEMENTIA IN FRONTAL-LOBE DEGENERATION OF NON-ALZHEIMER TYPE ARE NOT VARIANTS OF PRION DISEASE. J NEUROL NEUROSUR PS , 57 (6) 762 - 762.

Compton, D; DeVrieze, FW; Petersen, RC; Tangalos, E; Li, L; Hardy, J; (2002) Possible association between genetic variability at the apolipoprotein(a) locus and Alzheimer's disease in apolipoprotein E2 carriers. NEUROSCI LETT , 331 (1) 60 - 62.

Cookson, MR; Hardy, J; (2006) Clinical implications of basic research: The persistence of memory. NEW ENGLAND JOURNAL OF MEDICINE , 355 (25) 2697 - 2698. 10.1056/NEJMcibr065999.

Cookson, MR; Hardy, J; Lewis, PA; (2008) Genetic Neuropathology of Parkinson's Disease. INT J CLIN EXP PATHO , 1 (3) 217 - 231. Gold open access

Coon, KD; Myers, AJ; Craig, DW; Webster, JA; Pearson, JV; Lince, DH; ... Stephan, DA; + view all (2007) A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. JOURNAL OF CLINICAL PSYCHIATRY , 68 (4) 613 - 618.

Cooper-Knock, J; Hewitt, C; Highley, JR; Brockington, A; Milano, A; Man, S; ... Shaw, PJ; + view all (2012) Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72. Brain , 135 (3) 751 - 764. 10.1093/brain/awr365. Green and gold open access
file

Coppola, G; Chinnathambi, S; Lee, JJ; Dombroski, BA; Baker, MC; Soto-Ortolaza, AI; ... Geschwind, DH; + view all (2012) Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet , 21 (15) 3500 - 3512. 10.1093/hmg/dds161.

Corneveaux, JJ; Allen, AN; Pruzin, JJ; Chewning, K; Villa, SE; Meechoovet, HB; ... Hardy, J; + view all (2010) Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Human Molecular Genetics , 19 (16) 3295 - 3301. 10.1093/hmg/ddq221.

Corneveaux, JJ; Myers, AJ; Allen, AN; Pruzin, JJ; Ramirez, M; Engel, A; ... Huentelman, MJ; + view all (2010) Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. HUM MOL GENET , 19 (16) 3295 - 3301. 10.1093/hmg/ddq221.

Cortese, A; Tucci, A; Piccolo, G; Galimberti, CA; Fratta, P; Marchioni, E; ... Moggio, M; + view all (2014) Novel CLN3 mutation causing autophagic vacuolar myopathy. Neurology 10.1212/WNL.0000000000000490.

COWBURN, R; BARTON, A; HARDY, J; WESTER, P; WINBLAD, B; (1987) REGION-SPECIFIC DEFECTS IN GLUTAMATE AND GAMMA-AMINOBUTYRIC-ACID INNERVATION IN ALZHEIMERS-DISEASE. BIOCHEMICAL SOCIETY TRANSACTIONS , 15 (3) 505 - 506.

COWBURN, R; DODD, P; HARDY, J; JOHNSTON, G; (1987) A COMPARISON OF HIGH-AFFINITY SYNAPTOSOMAL UPTAKE OF D-ASPARTATE IN RAT AND HUMAN-BRAIN. NEUROCHEMISTRY INTERNATIONAL , 10 (3) 339 - 346. 10.1016/0197-0186(87)90108-2.

COWBURN, R; HARDY, J; BRIGGS, R; ROBERTS, P; (1989) CHARACTERIZATION, DENSITY, AND DISTRIBUTION OF KAINATE RECEPTORS IN NORMAL AND ALZHEIMERS DISEASED HUMAN-BRAIN. JOURNAL OF NEUROCHEMISTRY , 52 (1) 140 - 147. 10.1111/j.1471-4159.1989.tb10908.x.

COWBURN, R; HARDY, J; ROBERTS, P; (1988) CHARACTERIZATION OF NA+-INDEPENDENT L-[H-3]GLUTAMATE BINDING-SITES IN HUMAN TEMPORAL CORTEX. JOURNAL OF NEUROCHEMISTRY , 50 (6) 1872 - 1878. 10.1111/j.1471-4159.1988.tb02491.x.

COWBURN, R; HARDY, J; ROBERTS, P; BRIGGS, R; (1988) REGIONAL DISTRIBUTION OF PRESYNAPTIC AND POSTSYNAPTIC GLUTAMATERGIC FUNCTION IN ALZHEIMERS-DISEASE. BRAIN RESEARCH , 452 (1-2) 403 - 407. 10.1016/0006-8993(88)90048-0.

COWBURN, R; HARDY, J; ROBERTS, P; BRIGGS, R; (1988) PRESYNAPTIC AND POSTSYNAPTIC GLUTAMATERGIC FUNCTION IN ALZHEIMERS-DISEASE. NEUROSCIENCE LETTERS , 86 (1) 109 - 113. 10.1016/0304-3940(88)90192-9.

Crawford, F; Hardy, J; Mullan, M; Goate, A; Hughes, D; Fidani, L; ... Chartier-Harlin, MC; + view all (1991) Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence. Neurosci Lett , 133 (1) 1 - 2.

Crehan, H; Hardy, J; Pocock, J; (2013) Blockage of CR1 prevents activation of rodent microglia. Neurobiol Dis , 54 139 - 149. 10.1016/j.nbd.2013.02.003.

Crehan, H; Hardy, J; Pocock, J; (2012) Microglia, Alzheimer's disease, and complement. Int J Alzheimers Dis , 2012 983640 - ?. 10.1155/2012/983640. Gold open access

Crehan, H; Holton, P; Wray, S; Pocock, J; Guerreiro, R; Hardy, J; (2012) Complement receptor 1 (CR1) and Alzheimer's disease. Immunobiology , 217 (2) 244 - 250. 10.1016/j.imbio.2011.07.017.

Crook, R; Ellis, R; Shanks, M; Thal, LJ; PerezTur, J; Baker, M; ... Galasko, D; + view all (1997) Early-onset Alzheimer's disease with a presenilin-1 mutation at the site corresponding to the Volga German presenilin-2 mutation. ANNALS OF NEUROLOGY , 42 (1) 124 - 128. 10.1002/ana.410420121.

CROOK, R; HARDY, J; DUFF, K; (1994) SINGLE-DAY APOLIPOPROTEIN-E GENOTYPING. JOURNAL OF NEUROSCIENCE METHODS , 53 (2) 125 - 127. 10.1016/0165-0270(94)90168-6.

Crook, R; Verkkoniemi, A; Perez-Tur, J; Mehta, N; Baker, M; Houlden, H; ... Haltia, M; + view all (1998) A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1. NAT MED , 4 (4) 452 - 455.

Cruchaga, C; Karch, CM; Jin, SC; Benitez, BA; Cai, Y; Guerreiro, R; ... Goate, AM; + view all (2013) Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature 10.1038/nature12825.

Cruts, M; van Duijn, CM; Backhovens, H; Van den Broeck, M; Wehnert, A; Serneels, S; ... Van Broeckhoven, C; + view all (1998) Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population based study of presenile Alzheimer disease. HUMAN MOLECULAR GENETICS , 7 (1) 43 - 51. 10.1093/hmg/7.1.43.

DAVIES, D; HARDY, J; (1988) BLOOD-BRAIN BARRIER IN AGING AND ALZHEIMERS-DISEASE. NEUROBIOLOGY OF AGING , 9 (1) 46 - 48. 10.1016/S0197-4580(88)80017-4.

De Ferrari, GV; Papassotiropoulos, A; Biechele, T; De-Vrieze, FW; Avila, ME; Major, MB; ... Moon, RT; + view all (2007) Common genetic variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and late-onset Alzheimer's disease. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 104 (22) 9434 - 9439. 10.1073/pnas.0603523104.

De Jonghe, C; Cruts, M; Rogaeva, EA; Tysoe, C; Singleton, A; Vanderstichele, H; ... Van Broeckhoven, C; + view all (1999) Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased A beta 42 secretion. HUMAN MOLECULAR GENETICS , 8 (8) 1529 - 1540. 10.1093/hmg/8.8.1529.

de Silva, R; Hardy, J; Crook, J; Khan, N; Graham, EA; Morris, CM; ... Lees, AJ; + view all (2002) The tau locus is not significantly associated with pathologically confirmed sporadic Parkinson's disease. NEUROSCI LETT , 330 (2) 201 - 203.

Devine, MJ; Gwinn, K; Singleton, A; Hardy, J; (2011) Parkinson's Disease and alpha-Synuclein Expression. MOVEMENT DISORD , 26 (12) 2160 - 2168. 10.1002/mds.23948.

Devine, MJ; Kaganovich, A; Ryten, M; Mamais, A; Trabzuni, D; Manzoni, C; ... Lewis, PA; + view all (2011) Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue. PLOS ONE , 6 (7) , Article e22489. 10.1371/journal.pone.0022489. Green and gold open access
file

Devine, MJ; Ryten, M; Vodicka, P; Thomson, AJ; Burdon, T; Houlden, H; ... Kunath, T; + view all (2011) Parkinson's disease induced pluripotent stem cells with triplication of the alpha-synuclein locus. NAT COMMUN , 2 , Article 440. 10.1038/ncomms1453. Gold open access

Dickson, D; Farrer, M; Lincoln, S; Mason, RP; Zimmerman, TR; Golbe, LI; Hardy, J; (2001) Pathology of PD in monozygotic twins with a 20-year discordance interval. NEUROLOGY , 56 (7) 981 - 982.

Dickson, DW; Braak, H; Duda, JE; Duyckaerts, C; Gasser, T; Halliday, GM; ... Litvan, I; + view all (2009) Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. LANCET NEUROL , 8 (12) 1150 - 1157.

Dickson, DW; Liu, WK; Hardy, J; Farrer, M; Mehta, N; Uitti, R; ... Yen, SH; + view all (1999) Widespread alterations of alpha-synuclein in multiple system atrophy. AMERICAN JOURNAL OF PATHOLOGY , 155 (4) 1241 - 1251. 10.1016/S0002-9440(10)65226-1.

Dobricic, V; Stefanova, E; Jankovic, M; Gurunlian, N; Novakovic, I; Hardy, J; ... Guerreiro, R; + view all (2012) Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort. Neurobiol Aging , 33 (7) 1481.e7 - 1481.12. 10.1016/j.neurobiolaging.2011.12.007.

DODD, P; HAMBLEY, J; COWBURN, R; HARDY, J; (1988) A COMPARISON OF METHODOLOGIES FOR THE STUDY OF FUNCTIONAL TRANSMITTER NEUROCHEMISTRY IN HUMAN-BRAIN. JOURNAL OF NEUROCHEMISTRY , 50 (5) 1333 - 1345. 10.1111/j.1471-4159.1988.tb03013.x.

DODD, P; HARDY, J; BAIG, E; KIDD, A; BIRD, E; WATSON, W; JOHNSTON, G; (1986) OPTIMIZATION OF FREEZING, STORAGE, AND THAWING CONDITIONS FOR THE PREPARATION OF METABOLICALLY ACTIVE SYNAPTOSOMES FROM FROZEN RAT AND HUMAN-BRAIN. NEUROCHEMICAL PATHOLOGY , 4 (3) 177 - 198. 10.1007/BF02834357.

DODD, P; HARDY, J; BRADFORD, H; BENNETT, G; EDWARDSON, J; HARDING, B; (1979) METABOLIC AND SECRETORY PROCESSES IN NERVE-ENDINGS ISOLATED FROM POSTMORTEM BRAIN. NEUROSCIENCE LETTERS , 11 (1) 87 - 92. 10.1016/0304-3940(79)90061-2.

DODD, P; HARDY, J; OAKLEY, A; EDWARDSON, J; PERRY, E; DELAUNOY, J; (1981) A RAPID METHOD FOR PREPARING SYNAPTOSOMES - COMPARISON, WITH ALTERNATIVE PROCEDURES. BRAIN RESEARCH , 226 (1-2) 107 - 118. 10.1016/0006-8993(81)91086-6.

DODD, P; HARDY, J; OAKLEY, A; STRONG, A; (1981) SYNAPTOSOMES PREPARED FROM FRESH HUMAN CEREBRAL-CORTEX - MORPHOLOGY, RESPIRATION AND RELEASE OF TRANSMITTER AMINO-ACIDS. BRAIN RESEARCH , 224 (2) 419 - 425. 10.1016/0006-8993(81)90871-4.

DODD, P; WATSON, W; MORRISON, M; JOHNSTON, G; BIRD, E; COWBURN, R; HARDY, J; (1989) UPTAKE OF GAMMA-AMINOBUTYRIC ACID AND L-GLUTAMIC ACID BY SYNAPTOSOMES FROM POSTMORTEM HUMAN CEREBRAL-CORTEX - MULTIPLE SITES, SODIUM DEPENDENCE AND EFFECT OF TISSUE-PREPARATION. BRAIN RESEARCH , 490 (2) 320 - 331. 10.1016/0006-8993(89)90249-7.

Dogu, O; Johnson, J; Hernandez, D; Hanson, M; Hardy, J; Apaydin, H; ... Singleton, A; + view all (2004) A consanguineous Turkish family with early-onset Parkinson's disease and an exon 4 parkin deletion. MOVEMENT DISORDERS , 19 (7) 812 - 816. 10.1002/mds.20028.

Doherty, KM; Hardy, J; (2013) Parkin disease and the Lewy body conundrum. Movement Disorders , 28 (6) pp. 702-704. 10.1002/mds.25486. Green and gold open access
file

Doherty, KM; Moriyama, LS; Parkkinen, L; Healy, DG; Farrell, M; Mencacci, NE; ... Holton, JL; + view all (2013) Parkin disease-a clinicopathological entity? J Neurol Neurosurg Psychiatry , 84 (11) e2 - ?. 10.1136/jnnp-2013-306573.13.

Doherty, KM; Silveira-Moriyama, L; Parkkinen, L; Healy, DG; Farrell, M; Mencacci, NE; ... Holton, JL; + view all (2013) Parkin disease: a clinicopathologic entity? JAMA Neurol , 70 (5) 571 - 579. 10.1001/jamaneurol.2013.172.

Doherty, KM; Silveira-Moriyama, L; Parkkinen, L; Healy, DG; Farrell, M; Mencacci, NE; ... Holton, JL; + view all (2013) Parkin disease: A clinicopathologic entity? JAMA Neurology , 70 (5) 571 - 579.

Dong, J; Gao, J; Nalls, M; Gao, X; Huang, X; Han, J; ... International Parkinson's Disease Genomics Consortium (IPDGC),; + view all (2014) Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease. Neurobiol Aging , 35 (6) 1512.e5 - 1512.10. 10.1016/j.neurobiolaging.2013.12.020.

Duff, K; Eckman, C; Zehr, C; Yu, X; Prada, CM; Pereztur, J; ... Younkin, S; + view all (1996) Increased amyloid-beta 42(43) in brains of mice expressing mutant presenilin 1. NATURE , 383 (6602) 710 - 713. 10.1038/383710a0.

DUFF, K; HARDY, J; (1995) ALZHEIMERS-DISEASE - MOUSE MODEL MADE. NATURE , 373 (6514) 476 - 477. 10.1038/373476a0.

DUFF, K; MCGUIGAN, A; HUXLEY, C; SCHULZ, F; HARDY, J; (1994) INSERTION OF A PATHOGENIC MUTATION INTO A YEAST ARTIFICIAL CHROMOSOME CONTAINING THE HUMAN AMYLOID PRECURSOR PROTEIN GENE. GENE THERAPY , 1 (1) 70 - 75.

Duncan, AJ; Bitner-Glindzicz, M; Meunier, B; Costello, H; Hargreaves, IP; Lopez, LC; ... Rahman, S; + view all (2009) A Nonsense Mutation in COQ9 Causes Autosomal-Recessive Neonatal-Onset Primary Coenzyme Q(10) Deficiency: A Potentially Treatable Form of Mitochondrial Disease. AM J HUM GENET , 84 (5) 558 - 566. 10.1016/j.ajhg.2009.03.018. Gold open access

Duran, R; Hardy, J; McNeill, A; Schapira, AHV; Mehta, A; Hughes, D; ... Deegan, P; + view all (2012) Novel pathogenic mutations in the glucocerebrosidase locus. Molecular Genetics and Metabolism , 106 (4) 495 - 497. 10.1016/j.ymgme.2012.05.006.

Duran, R; McNeill, A; Mehta, A; Hughes, D; Cox, T; Deegan, P; ... Hardy, J; + view all (2012) Novel pathogenic mutations in the glucocerebrosidase locus. Mol Genet Metab , 106 (4) 495 - 497. 10.1016/j.ymgme.2012.05.006. Gold open access

Duran, R; Mencacci, NE; Angeli, AV; Shoai, M; Deas, E; Houlden, H; ... Foltynie, T; + view all (2013) The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease. Movement Disorders , 28 (2) 232 - 236. 10.1002/mds.25248. Green and gold open access
file

Eckman, CB; Mehta, ND; Crook, R; Pereztur, J; Prihar, G; Pfeiffer, E; ... Hardy, J; + view all (1997) A new pathogenic mutation in the APP gene (1716V) increases the relative proportion of A beta 42(43). HUMAN MOLECULAR GENETICS , 6 (12) 2087 - 2089. 10.1093/hmg/6.12.2087.

Edwards-Lee, T; Ringman, JM; Chung, J; Werner, J; Morgan, A; Hyslop, PS; ... Hardy, J; + view all (2005) An African American family with earlyonset Alzheimer disease and an APP (T714I) mutation. NEUROLOGY , 64 (2) 377 - 379.

Edwards-Lee, T; Wen, J; Bell, J; Hardy, J; Chung, J; Momeni, P; (2006) A presenilin-1 mutation (T245P) in transmembrane domain 6 causes early onset Alzheimer's disease. NEUROSCIENCE LETTERS , 398 (3) 251 - 252. 10.1016/j.neulet.2006.01.006.

Eerola, J; Hernandez, D; Launes, J; Hellstrom, O; Hague, S; Gulick, C; ... Singleton, AB; + view all (2003) Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD. NEUROLOGY , 61 (7) 1000 - 1002.

El-Agnaf, OMA; Salem, SA; Paleologou, KE; Cooper, LJ; Fullwood, NJ; Gibson, MJ; ... Allsop, D; + view all (2003) alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma. FASEB JOURNAL , 17 (11) 1945 - +. 10.1096/fj.03-0098fje.

Englund, E; Gustafson, L; Passant, U; Majounie, E; Renton, AE; Traynor, BJ; ... Hardy, J; + view all (2012) Familial Lund frontotemporal dementia caused by C9ORF72 hexanucleotide expansion. NEUROBIOLOGY OF AGING , 33 (8) , Article ARTN 1850.e13. 10.1016/j.neurobiolaging.2012.02.019.

Erro, R; Bhatia, KP; Hardy, J; (2014) GNAL Mutations and Dystonia. JAMA Neurol , 71 (8) 1052 - 1053. 10.1001/jamaneurol.2014.1506.

Escott-Price, V; Bellenguez, C; Wang, LS; Choi, SH; Harold, D; Jones, L; ... Williams, J; + view all (2014) Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease. PLoS One , 9 (6) e94661 - ?. 10.1371/journal.pone.0094661.

Evans, W; Fung, HC; Steele, J; Eerola, J; Tienari, P; Pittman, A; ... Hardy, J; + view all (2004) The tau H2 haplotype is almost exclusively Caucasian in origin. NEUROSCI LETT , 369 (3) 183 - 185. 10.1016/j.neulet.2004.05.119.

Evidente, VGH; Advincula, J; Esteban, R; Pasco, P; Alfon, JA; Natividad, FF; ... Singleton, A; + view all (2002) Phenomenology of "Lubag" or X-linked dystonia-parkinsonism. MOVEMENT DISORDERS , 17 (6) 1271 - 1277. 10.1002/mds.10271.

Evidente, VGH; Esteban, RP; Hernandez, JL; Natividad, FF; Advincula, J; Gwinn-Hardy, K; ... Singleton, A; + view all (2004) Smell testing is abnormal in 'lubag' or X-linked dystonia-parkinsonism: a pilot study. PARKINSONISM & RELATED DISORDERS , 10 (7) 407 - 410. 10.1016/j.parkreldis.2004.04.011.

Evidente, VGH; Gwinn-Hardy, K; Hardy, J; Hernandez, D; Singleton, A; (2002) X-linked dystonia ("Lubag") presenting predominantly with parkinsonism: A more benign phenotype? MOVEMENT DISORDERS , 17 (1) 200 - 202. 10.1002/mds.1263.

Farrer, M; Chan, P; Chen, R; Tan, L; Lincoln, S; Hernandez, D; ... Langston, JW; + view all (2001) Lewy bodies and parkinsonism in families with parkin mutations. ANNALS OF NEUROLOGY , 50 (3) 293 - 300. 10.1002/ana.1132.

Farrer, M; Destee, A; Levecque, C; Singleton, A; Engelender, S; Becquet, E; ... Chartier-Harlin, MC; + view all (2001) Genetic analysis of synphilin-1 in familial Parkinson's disease. NEUROBIOLOGY OF DISEASE , 8 (2) 317 - 323. 10.1006/nbdi.2000.0326.

Farrer, M; Destee, T; Becquet, E; Wavrant-De Vrieze, F; Mouroux, V; Richard, F; ... Chartier-Harlin, MC; + view all (2000) Linkage exclusion in French families with probable Parkinson's disease. MOVEMENT DISORDERS , 15 (6) 1075 - 1083. 10.1002/1531-8257(200011)15:6<1075::AID-MDS1004>3.0.CO;2-2.

Farrer, M; Gwinn-Hardy, K; Hutton, M; Hardy, J; (1999) The genetics of disorders with synuclein pathology and parkinsonism. HUMAN MOLECULAR GENETICS , 8 (10) 1901 - 1905. 10.1093/hmg/8.10.1901.

Farrer, M; Gwinn-Hardy, K; Muenter, M; DeVrieze, FW; Crook, R; Perez-Tur, J; ... Hardy, J; + view all (1999) A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor. HUMAN MOLECULAR GENETICS , 8 (1) 81 - 85. 10.1093/hmg/8.1.81.

Farrer, M; Maraganore, DM; Lockhart, P; Singleton, A; Lesnick, TG; de Andrade, M; ... Hernandez, D; + view all (2001) alpha-synuclein gene haplotypes are associated with Parkinson's disease. HUM MOL GENET , 10 (17) 1847 - 1851.

Farrer, M; Skipper, L; Berg, M; Bisceglio, G; Hanson, M; Hardy, J; ... Aasly, J; + view all (2002) The Tau H1 haplotype is associated with Parkinson's disease in the Norwegian population. NEUROSCIENCE LETTERS , 322 (2) , Article PII S0304-3940(02)00106-4. 10.1016/S0304-3940(02)00106-4.

Farrer, M; Wavrant-De Vrieze, F; Crook, R; Boles, L; Perez-Tur, J; Hardy, J; ... Lynch, T; + view all (1998) Low frequency of alpha-synuclein mutations in familial Parkinson's disease. ANNALS OF NEUROLOGY , 43 (3) 394 - 397. 10.1002/ana.410430320.

Ferrari, R; Hardy, J; Momeni, P; (2011) Frontotemporal Dementia: From Mendelian Genetics Towards Genome Wide Association Studies. JOURNAL OF MOLECULAR NEUROSCIENCE , 45 (3) 500 - 515. 10.1007/s12031-011-9635-y.

Ferrari, R; Hernandez, DG; Nalls, MA; Rohrer, JD; Ramasamy, A; Kwok, JB; ... Momeni, P; + view all (2014) Frontotemporal dementia and its subtypes: a genome-wide association study. Lancet Neurol , 13 (7) 686 - 699. 10.1016/S1474-4422(14)70065-1.

Ferrari, R; Kapogiannis, D; Huey, ED; Grafman, J; Hardy, J; Momeni, P; (2010) Novel Missense Mutation in Charged Multivesicular Body Protein 2B in a Patient With Frontotemporal Dementia. ALZ DIS ASSOC DIS , 24 (4) 397 - 401. 10.1097/WAD.0b013e3181df20c7.

Ferrari, R; Kero, M; Mok, K; Paetau, A; Tienari, PJ; Tynninen, O; ... Myllykangas, L; + view all (2013) A familial frontotemporal dementia associated with C9orf72 repeat expansion and dysplastic gangliocytoma. Neurobiol Aging 10.1016/j.neurobiolaging.2013.08.021.

Ferrari, R; Mok, K; Moreno, JH; Cosentino, S; Goldman, J; Pietrini, P; ... Momeni, P; + view all (2012) Screening for C9ORF72 repeat expansion in FTLD. Neurobiol Aging , 33 (8) 1850.e1 - 1850.11. 10.1016/j.neurobiolaging.2012.02.017.

Ferrari, R; Momeni, P; Mok, K; Hardy, J; Kero, M; Paetau, A; ... Verkkoniemi-Ahola, A; + view all (2014) A familial frontotemporal dementia associated with C9orf72 repeat expansion and dysplastic gangliocytoma. Neurobiology of Aging , 35 (2) 10.1016/j.neurobiolaging.2013.08.021.

Ferrari, R; Momeni, P; Simone, R; Nicolaou, N; Hondhamuni, G; Vandrovcova, J; ... Weale, ME; + view all (2014) Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy. Neurobiology of Aging , 35 (6) 10.1016/j.neurobiolaging.2014.01.010.

Ferrari, R; Momeni, P; Simone, R; Nicolaou, N; Hondhamuni, G; Vandrovcova, J; ... Weale, ME; + view all (2014) Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy. Neurobiology of Aging , 35 (6) 10.1016/j.neurobiolaging.2014.01.010.

Ferrari, R; Moreno, JH; Momeni, P; Mok, K; Hardy, J; Cosentino, S; ... Ghetti, B; + view all (2012) Screening for C9ORF72 repeat expansion in FTLD. Neurobiology of Aging , 33 (8) 10.1016/j.neurobiolaging.2012.02.017.

Ferrari, R; Ryten, M; Simone, R; Trabzuni, D; Nicolaou, N; Hondhamuni, G; ... de Silva, R; + view all (2014) Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy. Neurobiol Aging 10.1016/j.neurobiolaging.2014.01.010.

Fidani, L; Clarimon, J; Goulas, A; Hatzitolios, AI; Evans, W; Tsirogianni, E; ... Kotsis, A; + view all (2007) Association of phosphodiesterase 4D gene G0 haplotype and ischaemic stroke in a Greek population. EUROPEAN JOURNAL OF NEUROLOGY , 14 (7) 745 - 749. 10.1111/j.1468-1331.2007.01767.x.

Fidani, L; Compton, D; Hardy, J; Petersen, RC; Tangalos, E; Mirtsou, V; ... De Vrieze, FW; + view all (2002) No association between the lipoprotein lipase S447X polymorphism and Alzheimer's disease. NEUROSCI LETT , 322 (3) 192 - 194.

Fidani, L; Goulas, A; Crook, R; Petersen, RC; Tangalos, E; Kotsis, A; Hardy, J; (2004) An association study of the cholesteryl ester transfer protein TaqI B polymorphism with late onset Alzheimer's disease. NEUROSCIENCE LETTERS , 357 (2) 152 - 154. 10.1016/j.neulet.2003.11.071.

Fidani, L; Goulas, A; Mirtsou, V; Petersen, RC; Tangalos, E; Crook, R; Hardy, J; (2002) Interleukin-1A polymorphism is not associated with late onset Alzheimer's disease. NEUROSCIENCE LETTERS , 323 (1) , Article PII S0304-3940(02)00114-3. 10.1016/S0304-3940(02)00114-3.

Fidani, L; Kalinderi, K; Bostantjopoulou, S; Clarimon, J; Goulas, A; Katsarou, Z; ... Kotsis, A; + view all (2006) Association of the Tau haplotype with Parkinson's disease in the Greek population. MOVEMENT DISORDERS , 21 (7) 1036 - 1039. 10.1002/mds.20864.

FOLEY, P; BRADFORD, H; DOCHERTY, M; FILLIT, H; LUINE, V; MCEWEN, B; ... HARDY, J; + view all (1988) EVIDENCE FOR THE PRESENCE OF ANTIBODIES TO CHOLINERGIC NEURONS IN THE SERUM OF PATIENTS WITH ALZHEIMERS-DISEASE. JOURNAL OF NEUROLOGY , 235 (8) 466 - 471. 10.1007/BF00314249.

FOLEY, P; BRADFORD, H; DOCHERTY, M; FILLIT, H; LUINE, V; MCEWEN, B; ... HARDY, J; + view all (1987) EVIDENCE FOR THE PRESENCE OF ANTIBODIES TO CHOLINERGIC NEURONS IN THE SERUM OF PATIENTS WITH ALZHEIMERS-DISEASE. BIOCHEMICAL SOCIETY TRANSACTIONS , 15 (6) 1034 - 1036.

Forabosco, P; Ramasamy, A; Trabzuni, D; Bras, J; Hardy, J; Guerreiro, R; ... Pocock, JM; + view all (2013) Insights into TREM2 biology by network analysis of human brain gene expression data. Neurobiology of Aging , 34 (12) 2699 - 2714. 10.1016/j.neurobiolaging.2013.05.001.

Forabosco, P; Ramasamy, A; Trabzuni, D; Walker, R; Smith, C; Bras, J; ... Ryten, M; + view all (2013) Insights into TREM2 biology by network analysis of human brain gene expression data. Neurobiol Aging , 34 (12) pp. 2699-2714. 10.1016/j.neurobiolaging.2013.05.001. Green and gold open access
file

Fox, NC; Kennedy, AM; Harvey, RJ; Lantos, PL; Roques, PK; Collinge, J; ... Rossor, MN; + view all (1997) Clinicopathological features of familial Alzheimer's disease associated with the M139V mutation in the presenilin 1 gene - Pedigree but not mutation specific age at onset provides evidence for a further genetic factor. BRAIN , 120 491 - 501.

Frank, RA; Galasko, D; Hampel, H; Hardy, J; de Leon, MJ; Mehta, PD; ... Trojanowski, JQ; + view all (2003) Biological markers for therapeutic trials in Alzheimer's disease - Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease. NEUROBIOLOGY OF AGING , 24 (4) 521 - 536. 10.1016/S0197-4580(03)00002-2.

Fratta, P; Charnock, J; Collins, T; Devoy, A; Howard, R; Malaspina, A; ... Fisher, EM; + view all (2013) Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry , 85 pp. 506-508. 10.1136/jnnp-2013-306761. Green and gold open access
file

Friedland, RP; Shah, JJ; Rebolledo-Mendez, JD; Farrer, LA; Vardarajan, B; Mok, K; Hardy, J; (2012) Behavioral variant frontotemporal lobar degeneration with amyotrophic lateral sclerosis with a chromosome 9p21 hexanucleotide repeat. Frontiers in Neurology , OCT 10.3389/fneur.2012.00136. Gold open access

Froelich, S; Houlden, H; Rizzu, P; Chakraverty, S; Baker, M; Kwon, J; ... Heutink, P; + view all (1999) Construction of a detailed physical and transcript map of the FTDP-17 candidate region on chromosome 17q21. GENOMICS , 60 (2) 129 - 136.

Fung, HC; Chen, CM; Hardy, J; Hernandez, D; Singleton, A; Wu, YR; (2006) Lack of G2019S LRRK2 mutation in a cohort of Taiwanese with sporadic Parkinson's disease. MOVEMENT DISORD , 21 (6) 880 - 881. 10.1002/mds.20814.

Fung, HC; Chen, CM; Hardy, J; Singleton, AB; Lee-Chen, GJ; Wu, YR; (2006) Analysis of the PINK1 gene in a cohort of patients with sporadic early-onset parkinsonism in Taiwan. NEUROSCI LETT , 394 (1) 33 - 36. 10.1016/j.neulet.2005.10.005.

Fung, HC; Chen, CM; Hardy, J; Singleton, AB; Wu, YR; (2006) A common genetic factor for Parkinson disease in ethnic Chinese population in Taiwan. BMC Neurology , 6 , Article 47. 10.1186/1471-2377-6-47. Green and gold open access
file

Fung, HC; Evans, J; Evans, W; Duckworth, J; Pittman, A; de Silva, R; ... Hardy, J; + view all (2005) The architecture of the tau haplotype block in different ethnicities. NEUROSCI LETT , 377 (2) 81 - 84. 10.1016/j.neulet.2004.11.072.

Fung, HC; Scholz, S; Matarin, M; Simon-Sanchez, J; Hernandez, D; Britton, A; ... Singleton, A; + view all (2006) Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data. LANCET NEUROL , 5 (11) 911 - 916. 10.1016/S1474-4422(06)70578-6.

Fung, HC; Xiromerisiou, G; Gibbs, JR; Wu, YR; Eerola, J; Gourbali, V; ... Singleton, AB; + view all (2006) Association of tau haplotype-tagging polymorphisms with Parkinson's disease in diverse ethnic Parkinson's disease cohorts. NEURODEGENER DIS , 3 (6) 327 - 333. 10.1159/000097301.

Furtado, S; Payami, H; Lockhart, PJ; Hanson, M; Nutt, JG; Singleton, AA; ... Stoessl, AJ; + view all (2004) Profile of families with parkinsonism-predominant spinocerebellar ataxia type 2 (SCA2). MOVEMENT DISORDERS , 19 (6) 622 - 629. 10.1002/mds.20074.

Garcia, ML; Singleton, AB; Hernandez, D; Ward, CM; Evey, C; Sapp, PA; ... Cleveland, DW; + view all (2006) Mutations in neurofilament genes are not a significant primary cause of non-SOD1-mediated amyotrophic lateral sclerosis. NEUROBIOLOGY OF DISEASE , 21 (1) 102 - 109. 10.1016/j.nbd.2005.06.016.

Gasser, T; Hardy, J; Mizuno, Y; (2011) Milestones in PD Genetics. MOVEMENT DISORD , 26 (6) 1042 - 1048. 10.1002/mds.23637.

Gegg, ME; Burke, D; Heales, SJ; Cooper, JM; Hardy, J; Wood, NW; Schapira, AH; (2012) Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains. Ann Neurol , 72 (3) 455 - 463. 10.1002/ana.23614.

Gerrish, A; Russo, G; Richards, A; Moskvina, V; Ivanov, D; Harold, D; ... Pankratz, VS; + view all (2012) The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. Journal of Alzheimer's Disease , 28 (2) 377 - 387. 10.3233/JAD-2011-110824.

Gerrish, A; Russo, G; Richards, A; Moskvina, V; Ivanov, D; Harold, D; ... Williams, J; + view all (2012) The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. J Alzheimers Dis , 28 (2) 377 - 387. 10.3233/JAD-2011-110824.

GOATE, A; CHARTIERHARLIN, M; MULLAN, M; BROWN, J; CRAWFORD, F; FIDANI, L; ... HARDY, J; + view all (1991) SEGREGATION OF A MISSENSE MUTATION IN THE AMYLOID PRECURSOR PROTEIN GENE WITH FAMILIAL ALZHEIMERS-DISEASE. NATURE , 349 (6311) 704 - 706. 10.1038/349704a0.

Goate, A; Hardy, J; (2012) Twenty years of Alzheimer's disease-causing mutations. J Neurochem , 120 Suppl 1 3 - 8. 10.1111/j.1471-4159.2011.07575.x.

GOATE, AM; HAYNES, AR; OWEN, MJ; FARRALL, M; JAMES, LA; LAI, LYC; ... HARDY, JA; + view all (1989) PREDISPOSING LOCUS FOR ALZHEIMERS-DISEASE ON CHROMOSOME-21. LANCET , 1 (8634) 352 - 355.

Goldstein, DS; Imrich, R; Peckham, E; Holmes, C; Lopez, G; Crews, C; ... Hallett, M; + view all (2007) Neurocirculatory and nigrostriatal abnormalities in Parkinson disease from LRRK2 mutation. NEUROLOGY , 69 (16) 1580 - 1584. 10.1212/01.wnl.0000268696.57912.64.

Goudreau, JL; Maraganore, DM; Farrer, MJ; Lesnick, TG; Singleton, AB; Bower, JH; ... Rocca, WA; + view all (2002) Case-control study of dopamine transporter-1, monoamine oxidase-B, and catechol-O-methyl transferase polymorphisms in Parkinson's disease. MOVEMENT DISORDERS , 17 (6) 1305 - 1311. 10.1002/mds.10268.

Goulas, A; Fidani, L; Kotsis, A; Mirtsou, V; Petersen, RC; Tangalos, E; Hardy, J; (2002) An association study of a functional catalase gene polymorphism,-262C -> T, and patients with Alzheimer's disease. NEUROSCI LETT , 330 (2) 210 - 212.

Grunberg, J; Walter, J; Eckman, C; Capell, A; Schindzielorz, A; Younkin, S; ... Haass, C; + view all (1998) Truncated presenilin 2 derived from differentially spliced mRNAs does not affect the ratio of amyloid beta-peptide 1-42/1-40. NEUROREPORT , 9 (14) 3293 - 3299.

Grupe, A; Li, YH; Rowland, C; Nowotny, P; Hinrichs, AL; Smemo, S; ... Goate, A; + view all (2006) A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. AMERICAN JOURNAL OF HUMAN GENETICS , 78 (1) 78 - 88. 10.1086/498851.

Guerreiro, R; Brás, J; Hardy, J; (2013) SnapShot: Genetics of Alzheimer's Disease. Cell , 155 (4) 968 - 968.e1. 10.1016/j.cell.2013.10.037.

Guerreiro, R; Brás, J; Hardy, J; Singleton, A; (2014) Next generation sequencing techniques in neurological diseases: redefining clinical and molecular associations. Hum Mol Genet , 23 (R1) R47-R53. 10.1093/hmg/ddu203. Green and gold open access
file

Guerreiro, R; Brás, J; Wojtas, A; Rademakers, R; Hardy, J; Graff-Radford, N; (2014) A nonsense mutation in PRNP associated with clinical Alzheimer's disease. Neurobiol Aging 10.1016/j.neurobiolaging.2014.05.013.

Guerreiro, R; Hardy, J; (2014) Genetics of Alzheimer's Disease. Neurotherapeutics 10.1007/s13311-014-0295-9.

Guerreiro, R; Hardy, J; (2013) TREM2 and neurodegenerative disease. N Engl J Med , 369 (16) 1569 - 1570.

Guerreiro, R; Hardy, J; (2013) Drs. Kuerreiro and Hardy reply. New England Journal of Medicine , 369 (16) 1569 - 1570. 10.1056/NEJMc1306509.

Guerreiro, R; Kara, E; Le Ber, I; Bras, J; Rohrer, JD; Taipa, R; ... Houlden, H; + view all (2013) Genetic analysis of inherited leukodystrophies: genotype-phenotype correlations in the CSF1R gene. JAMA Neurol , 70 (7) 875 - 882. 10.1001/jamaneurol.2013.698.

Guerreiro, R; Wojtas, A; Bras, J; Carrasquillo, M; Rogaeva, E; Majounie, E; ... Alzheimer Genetic Analysis Group,; + view all (2013) TREM2 variants in Alzheimer's disease. N Engl J Med , 368 (2) 117 - 127. 10.1056/NEJMoa1211851.

Guerreiro, R; Wojtas, A; Bras, J; Carrasquillo, M; Rogaeva, E; Majounie, E; ... Grp, AGA; + view all (2013) TREM2 Variants in Alzheimer's Disease. NEW ENGLAND JOURNAL OF MEDICINE , 368 (2) 117 - 127. 10.1056/NEJMoa1211851.

Guerreiro, RJ; Baquero, M; Blesa, R; Boada, M; Bras, JM; Bullido, MJ; ... Clarimon, J; + view all (2010) Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP. NEUROBIOL AGING , 31 (5) 725 - 731. 10.1016/j.neurobiolaging.2008.06.012.

Guerreiro, RJ; Beck, J; Gibbs, JR; Santana, I; Rossor, MN; Schott, JM; ... Hardy, J; + view all (2010) Genetic Variability in CLU and Its Association with Alzheimer's Disease. PLOS ONE , 5 (3) , Article e9510. 10.1371/journal.pone.0009510. Green and gold open access
file

Guerreiro, RJ; Bras, JM; Santana, I; Januario, C; Santiago, B; Morgadinho, AS; ... Oliveira, C; + view all (2006) Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort. BMC Neurology , 6 , Article 24. 10.1186/1471-2377-6-24. Green and gold open access
file

Guerreiro, RJ; Gustafson, DR; Hardy, J; (2012) The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE. Neurobiology of Disease , 33 (3) 437 - 456. 10.1016/j.neurobiolaging.2010.03.025. Green and gold open access
file

Guerreiro, RJ; Hardy, J; (2012) TOMM40 Association With Alzheimer Disease Tales of APOE and Linkage Disequilibrium. ARCHIVES OF NEUROLOGY , 69 (10) 1243 - 1244. 10.1001/archneurol.2012.1935.

Guerreiro, RJ; Hardy, J; (2011) Alzheimer's disease genetics: lessons to improve disease modelling. BIOCHEM SOC T , 39 910 - 916. 10.1042/BST0390910.

Guerreiro, RJ; Lohmann, E; Brás, JM; Gibbs, JR; Rohrer, JD; Gurunlian, N; ... Hardy, J; + view all (2013) Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement. JAMA Neurol , 70 (1) 78 - 84. 10.1001/jamaneurol.2013.579.

Guerreiro, RJ; Santana, I; Bras, JM; Revesz, T; Rebelo, O; Ribeiro, MH; ... Hardy, J; + view all (2008) Novel progranulin mutation: Screening for PGRN mutations in a Portuguese series of FTD/CBS cases. MOVEMENT DISORD , 23 (9) 1269 - 1273. 10.1002/mds.22078.

Guerreiro, RJ; Vaskov, T; Crews, C; Singleton, A; Hardy, J; (2009) A Case of Dementia With PRNP D178Ncis-129M and No Insomnia. ALZ DIS ASSOC DIS , 23 (4) 415 - 417.

Guerreiro, RJ; Washecka, N; Hardy, J; Singleton, A; (2010) A Thorough Assessment of Benign Genetic Variability in GRN and MAPT. HUM MUTAT , 31 (2) E1126 - E1140. 10.1002/humu.21152.

Gwinn, K; Corriveau, RA; Mitsumoto, H; Bednarz, K; Jr, BRH; Cudkowicz, M; ... Grp, ALSR; + view all (2007) Amyotrophic Lateral Sclerosis: An Emerging Era of Collaborative Gene Discovery. PLOS ONE , 2 (12) , Article e1254. 10.1371/journal.pone.0001254. Green and gold open access
file

Gwinn, K; Devine, MJ; Jin, LW; Johnson, J; Bird, T; Muenter, M; ... Singleton, A; + view all (2011) Clinical Features, with Video Documentation, of the Original Familial Lewy Body Parkinsonism Caused By alpha-Synuclein Triplication (Iowa Kindred). MOVEMENT DISORD , 26 (11) 2134 - 2136. 10.1002/mds.23776.

Gwinn-Hardy, K; Chen, JY; Liu, HC; Liu, TY; Boss, M; Seltzer, W; ... Farrer, M; + view all (2000) Spinocerebellar ataxia type 2 with parkinsonism in ethnic Chinese. NEUROLOGY , 55 (6) 800 - 805.

Gwinn-Hardy, K; Evidente, VGH; Waters, C; Muenter, MD; Hardy, J; (1999) L-dopa slows the progression of familial parkinsonism. LANCET , 353 (9167) 1850 - 1851. 10.1016/S0140-6736(99)01398-7.

Gwinn-Hardy, K; Mehta, ND; Farrer, M; Maraganore, D; Muenter, M; Yen, SH; ... Dickson, DW; + view all (2000) Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. ACTA NEUROPATHOLOGICA , 99 (6) 663 - 672.

Gwinn-Hardy, K; Singleton, A; O'Suilleabhain, P; Boss, M; Nicholl, D; Adam, A; ... Farrer, M; + view all (2001) Spinocerebellar ataxia type 3 phenotypically resembling Parkinson disease in a black family. ARCHIVES OF NEUROLOGY , 58 (2) 296 - 299. 10.1001/archneur.58.2.296.

Gwinn-Hardy, KA; Crook, R; Lincoln, S; Adler, CH; Caviness, JN; Hardy, J; Farrer, M; (2000) A kindred with Parkinson's disease not showing genetic linkage to established loci. NEUROLOGY , 54 (2) 504 - 507.

Haack, TB; Cuno, SM; Strom, TM; Meitinger, T; Prokisch, H; Wieland, T; ... Boddaert, N; + view all (2012) Exome sequencing reveals de novo WDR45 mutations causing a phenotypically distinct, X-linked dominant form of NBIA. American Journal of Human Genetics , 91 (6) 1144 - 1149. 10.1016/j.ajhg.2012.10.019.

Haack, TB; Hogarth, P; Kruer, MC; Gregory, A; Wieland, T; Schwarzmayr, T; ... Hayflick, SJ; + view all (2012) Exome sequencing reveals de novo WDR45 mutations causing a phenotypically distinct, X-linked dominant form of NBIA. Am J Hum Genet , 91 (6) 1144 - 1149. 10.1016/j.ajhg.2012.10.019.

HAAN, J; HARDY, J; ROOS, R; (1991) HEREDITARY CEREBRAL-HEMORRHAGE WITH AMYLOIDOSIS - DUTCH TYPE - ITS IMPORTANCE FOR ALZHEIMER RESEARCH. TRENDS IN NEUROSCIENCES , 14 (6) 231 - 234. 10.1016/0166-2236(91)90120-J.

Hague, S; Rogaeva, E; Hernandez, D; Gulick, C; Singleton, A; Hanson, M; ... Singleton, A; + view all (2003) Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation. ANNALS OF NEUROLOGY , 54 (2) 271 - 274. 10.1002/ana.10663.

HALTIA, M; VIITANEN, M; SULKAVA, R; ALAHURULA, V; POYHONEN, M; GOLDFARB, L; ... HARDY, J; + view all (1994) CHROMOSOME 14-ENCODED ALZHEIMERS-DISEASE - GENETIC AND CLINICOPATHOLOGICAL DESCRIPTION. ANN NEUROL , 36 (3) 362 - 367.

Hampel, H; Frank, R; Broich, K; Teipel, SJ; Katz, RG; Hardy, J; ... Blennow, K; + view all (2010) Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives. NAT REV DRUG DISCOV , 9 (7) 560 - 574. 10.1038/nrd3115.

Hamshere, ML; Holmans, PA; Avramopoulos, D; Bassett, SS; Blacker, D; Bertram, L; ... Owen, MJ; + view all (2007) Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. HUM MOL GENET , 16 (22) 2703 - 2712. 10.1093/hmg/ddm224.

Hanson, M; Honour, M; Singleton, A; Crawley, A; Singleton, A; Hardy, J; Gwinn-Hardy, K; (2004) Analysis of familial and sporadic restless legs syndrome in age of onset, gender, and severity features. JOURNAL OF NEUROLOGY , 251 (11) 1398 - 1401. 10.1007/s00415-004-0552-7.

Hardy, J; (2013) The ignoble art. NEW SCIENTIST , 219 (2929) 26 - 27.

Hardy, J; (2013) Psychiatric Genetics Are We There Yet? JAMA PSYCHIATRY , 70 (6) 569 - 570. 10.1001/jamapsychiatry.2013.216.

Hardy, J; (2013) Reply to Letter: Identical twins with leucine rich repeat kinase type 2 mutations discordant for Parkinson's disease. Movement Disorders , 28 (4) 561 - 562. 10.1002/mds.25415.

Hardy, J; (2013) Reply to Letter: Identical twins with leucine rich repeat kinase type 2 mutations discordant for Parkinson's disease. Mov Disord , 28 (4) 561 - 562. 10.1002/mds.25415.

Hardy, J; (2012) CSF biomarking for diagnosis and treatment assessment in neurodegeneration. JOURNAL OF NEUROCHEMISTRY , 123 (3) 339 - 341. 10.1111/j.1471-4159.2012.07928.x.

Hardy, J; (2012) Genetic analysis of disease in the era of whole genome analysis and public databases. Neurobiol Aging , 33 (4) 635 - ?. 10.1016/j.neurobiolaging.2011.12.039.

Hardy, J; (2011) Read all about it! NEW SCI , 211 (2822) 22 - 23.

Hardy, J; (2010) Genetic Analysis of Pathways to Parkinson Disease. NEURON , 68 (2) 201 - 206. 10.1016/j.neuron.2010.10.014. Gold open access

Hardy, J; (2010) Sample Tracking and Use in Published Genome-wide Association Studies. ARCH NEUROL-CHICAGO , 67 (10) 1267 - 1268.

Hardy, J; (2010) Neurological Diagnoses Identify Molecular Processes. ARCH NEUROL-CHICAGO , 67 (4) 400 - 401.

Hardy, J; (2009) The amyloid hypothesis for Alzheimer's disease: a critical reappraisal. J NEUROCHEM , 110 (4) 1129 - 1134. 10.1111/j.1471-4159.2009.06181.x.

Hardy, J; (2008) Race, genetics, and medicine at a crossroads. LANCET S85 - S89.

Hardy, J; (2007) Does A beta 42 have a function related to blood homeostasis? NEUROCHEMICAL RESEARCH , 32 (4-5) 833 - 835. 10.1007/s11064-006-9221-9.

Hardy, J; (2007) Putting presenilins centre stage - Introduction to the Talking Point on the role of presenilin mutations in Alzheimer disease. EMBO REPORTS , 8 (2) 134 - 135. 10.1038/sj.embor.7400899.

Hardy, J; (2006) A hundred years of Alzheimer's disease research. NEURON , 52 (1) 3 - 13. 10.1016/j.neuron.2006.09.016.

Hardy, J; (2006) Bad luck: An unappreciated limitation in the interpretation of twin studies. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS , 141B (6) 681 - 681. 10.1002/ajmg.b.30353.

Hardy, J; (2006) Amyloid double trouble. NATURE GENETICS , 38 (1) 11 - 12. 10.1038/ng0106-11.

Hardy, J; (2006) No definitive evidence for a role for the environment in the etiology of Parkinson's disease. MOVEMENT DISORDERS , 21 (10) 1790 - 1791. 10.1002/mds.21067.

Hardy, J; (2004) Is amyloid plaque imaging the key to monitoring brain pathology of Alzheimer's disease in vivo? For. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING , 31 (11) 1539 - 1540. 10.1007/s00259-004-1676-9.

Hardy, J; (2004) The uncertain anatomy of Alzheimer's disease. NEUROBIOLOGY OF AGING , 25 (6) 719 - 720. 10.1016/j.neurobiolaging.2003.12.012.

Hardy, J; (2004) Toward Alzheimer therapies based on genetic knowledge. ANNUAL REVIEW OF MEDICINE , 55 15 - 25. 10.1146/annurev.med.55.091902.103607.

Hardy, J; (2003) Alzheimer's disease: Genetic evidence points to a single pathogenesis. ANNALS OF NEUROLOGY , 54 (2) 143 - 144. 10.1002/ana.10624.

Hardy, J; (2003) The relationship between Lewy body disease, Parkinson's disease, and Alzheimer's disease. Annals of the New York Academy of Sciences , 991 167 - 170.

Hardy, J; (2003) The relationship between amyloid and tau. JOURNAL OF MOLECULAR NEUROSCIENCE , 20 (2) 203 - 206. 10.1385/JMN:20:2:203.

Hardy, J; (2002) Pathways to primary neurodegenerative disease. NEUROLOGIA , 17 (8) 399 - 401.

Hardy, J; (2002) The real problem in association studies. AMERICAN JOURNAL OF MEDICAL GENETICS , 114 (2) 253 - 253. 10.1002/ajmg.10294.

Hardy, J; (2002) Testing times for the "amyloid cascade hypothesis". NEUROBIOLOGY OF AGING , 23 (6) , Article PII S0197-4580(02)00042-8. 10.1016/S0197-4580(02)00042-8.

Hardy, J; (2001) The human genome is sequenced - What does it mean and why is it important? ARCHIVES OF NEUROLOGY , 58 (11) 1748 - 1749. 10.1001/archneur.58.11.1748.

Hardy, J; (2001) Genetic dissection of neurodegenerative disease. CLINICAL NEUROSCIENCE RESEARCH , 1 (1-2) , Article PII S1566-2772(00)00013-X. 10.1016/S1566-2772(00)00013-X.

Hardy, J; (1999) Pathways to primary neurodegenerative disease. MAYO CLINIC PROCEEDINGS , 74 (8) 835 - 837.

Hardy, J; (1999) The shorter amyloid cascade hypothesis. NEUROBIOLOGY OF AGING , 20 (1) 85 - 85.

Hardy, J; (1997) The 'amyloid cascade hypothesis' of AD: decoy or real McCoy? Reply. TRENDS IN NEUROSCIENCES , 20 (12) 559 - 559.

Hardy, J; (1997) Amyloid, the presenilins and Alzheimer's disease. TRENDS IN NEUROSCIENCES , 20 (4) 154 - 159. 10.1016/S0166-2236(96)01030-2.

Hardy, J; (1997) The Alzheimer family of diseases: Many etiologies, one pathogenesis? PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 94 (6) 2095 - 2097. 10.1073/pnas.94.6.2095.

Hardy, J; (1996) New insights into the genetics of Alzheimer's disease. ANNALS OF MEDICINE , 28 (3) 255 - 258. 10.3109/07853899609033127.

HARDY, J; (1995) APOLIPOPROTEIN-E IN THE GENETICS AND EPIDEMIOLOGY OF ALZHEIMERS-DISEASE. AMERICAN JOURNAL OF MEDICAL GENETICS , 60 (5) 456 - 460. 10.1002/ajmg.1320600519.

HARDY, J; (1994) LEWY BODIES IN ALZHEIMERS-DISEASE IN WHICH THE PRIMARY LESION IS A MUTATION IN THE AMYLOID PRECURSOR PROTEIN. NEUROSCIENCE LETTERS , 180 (2) 290 - 291. 10.1016/0304-3940(94)90541-X.

HARDY, J; (1994) ALZHEIMERS-DISEASE - CLINICAL MOLECULAR-GENETICS. CLINICS IN GERIATRIC MEDICINE , 10 (2) 239 - 247.

HARDY, J; (1994) APOE, AMYLOID, AND ALZHEIMERS-DISEASE. SCIENCE , 263 (5146) 454 - 455. 10.1126/science.8290946.

HARDY, J; (1993) PRION DEMENTIA. LANCET , 341 (8845) 626 - 626.

HARDY, J; (1992) FRAMING BETA-AMYLOID. NATURE GENETICS , 1 (4) 233 - 234. 10.1038/ng0792-233.

HARDY, J; (1992) AN ANATOMICAL CASCADE HYPOTHESIS FOR ALZHEIMERS-DISEASE. TRENDS IN NEUROSCIENCES , 15 (6) 200 - 201. 10.1016/0166-2236(92)90033-5.

HARDY, J; (1991) PRION DIMERS - A DEADLY DUO. TRENDS IN NEUROSCIENCES , 14 (10) 423 - 424. 10.1016/0166-2236(91)90038-V.

HARDY, J; (1991) MOLECULAR CLASSIFICATION OF ALZHEIMERS-DISEASE. LANCET , 337 (8753) 1342 - 1343.

HARDY, J; (1989) SLOW VIRUS DEMENTIAS - PRION GENE HOLDS THE KEY. TRENDS IN NEUROSCIENCES , 12 (5) 168 - 169. 10.1016/0166-2236(89)90062-3.

HARDY, J; (1988) FRIEDREICHS ATAXIA GENE LOCALIZED TO CHROMOSOME-9. TRENDS IN NEUROSCIENCES , 11 (11) 479 - 479. 10.1016/0166-2236(88)90005-7.

HARDY, J; (1988) MOLECULAR-BIOLOGY AND ALZHEIMERS-DISEASE - MORE QUESTIONS THAN ANSWERS. TRENDS IN NEUROSCIENCES , 11 (7) 293 - 294. 10.1016/0166-2236(88)90088-4.

HARDY, J; (1988) MOUSE MODELS OF HUMAN NEUROGENETIC DISORDERS. TRENDS IN NEUROSCIENCES , 11 (3) 89 - 90. 10.1016/0166-2236(88)90148-8.

HARDY, J; ADOLFSSON, R; ALAFUZOFF, I; BUCHT, G; MARCUSSON, J; NYBERG, P; ... WINBLAD, B; + view all (1985) TRANSMITTER DEFICITS IN ALZHEIMERS-DISEASE. NEUROCHEMISTRY INTERNATIONAL , 7 (4) 545 - 563. 10.1016/0197-0186(85)90050-6.

HARDY, J; ALLSOP, D; (1991) AMYLOID DEPOSITION AS THE CENTRAL EVENT IN THE ETIOLOGY OF ALZHEIMERS-DISEASE. TRENDS IN PHARMACOLOGICAL SCIENCES , 12 (10) 383 - 388. 10.1016/0165-6147(91)90609-V.

HARDY, J; BARTON, A; LOFDAHL, E; CHEETHAM, S; JOHNSTON, G; DODD, P; (1986) UPTAKE OF GAMMA-AMINOBUTYRIC-ACID AND GLYCINE BY SYNAPTOSOMES FROM POSTMEM HUMAN-BRAIN. JOURNAL OF NEUROCHEMISTRY , 47 (2) 460 - 467.

HARDY, J; BATEMAN, D; KIDD, A; EDWARDSON, J; SINGH, G; DODD, P; (1984) AMINO-ACID-TRANSPORT BY SYNAPTOSOMES ISOLATED FROM POST-MORTEM HUMAN-BRAIN. JOURNAL OF NEURAL TRANSMISSION , 60 (1) 57 - 62. 10.1007/BF01254765.

HARDY, J; BELLEROCHE, J; BORDER, D; BRADFORD, H; (1980) DIFFERENTIAL TRANSMITTER RELEASE FROM NERVE-TERMINALS ISOLATED FROM BASAL GANGLIA AND SUBSTANTIA NIGRA. JOURNAL OF NEUROCHEMISTRY , 34 (5) 1130 - 1139. 10.1111/j.1471-4159.1980.tb09952.x.

HARDY, J; BOAKES, R; THOMAS, D; KIDD, A; EDWARDSON, J; VIRMANI, M; ... DODD, P; + view all (1984) RELEASE OF ASPARTATE AND GLUTAMATE CAUSED BY CHLORIDE REDUCTION IN SYNAPTOSOMAL INCUBATION MEDIA. JOURNAL OF NEUROCHEMISTRY , 42 (3) 875 - 877. 10.1111/j.1471-4159.1984.tb02763.x.

Hardy, J; Bogdanovic, N; Winblad, B; Portelius, E; Andreasen, N; Cedazo-Minguez, A; Zetterberg, H; (2014) Pathways to Alzheimer's disease. J Intern Med , 275 (3) 296 - 303.

Hardy, J; Cai, H; Cookson, MR; Gwinn-Hardy, K; Singleton, A; (2006) Genetics of Parkinson's disease and parkinsonism. ANNALS OF NEUROLOGY , 60 (4) 389 - 398. 10.1002/ana.21022.

HARDY, J; CHARTIERHARLIN, M; MULLAN, M; (1992) ALZHEIMER-DISEASE - THE NEW AGENDA. AMERICAN JOURNAL OF HUMAN GENETICS , 50 (3) 648 - 651.

Hardy, J; Coleman, PD; (2009) Genetic Analysis Publications in Neurobiology of Aging. NEUROBIOLOGY OF AGING , 30 (4) 506 - 506. 10.1016/j.neurobiolaging.2009.01.003.

Hardy, J; Cookson, MR; Singleton, A; (2003) Genes and parkinsonism. LANCET NEUROLOGY , 2 (4) 221 - 228. 10.1016/S1474-4422(03)00350-8.

HARDY, J; COWBURN, R; (1987) GLUTAMATE NEUROTOXICITY AND ALZHEIMERS-DISEASE. TRENDS IN NEUROSCIENCES , 10 (10) 406 - 406. 10.1016/0166-2236(87)90008-7.

HARDY, J; COWBURN, R; BARTON, A; REYNOLDS, G; DODD, P; WESTER, P; ... WINBLAD, B; + view all (1987) A DISORDER OF CORTICAL GABAERGIC INNERVATION IN ALZHEIMERS-DISEASE. NEUROSCIENCE LETTERS , 73 (2) 192 - 196. 10.1016/0304-3940(87)90016-4.

HARDY, J; COWBURN, R; BARTON, A; REYNOLDS, G; LOFDAHL, E; OCARROLL, A; ... WINBLAD, B; + view all (1987) GLUTAMATE DEFICITS IN ALZHEIMERS-DISEASE. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 50 (3) 356 - 357.

HARDY, J; COWBURN, R; BARTON, A; REYNOLDS, G; LOFDAHL, E; OCARROLL, A; ... WINBLAD, B; + view all (1987) REGION-SPECIFIC LOSS OF GLUTAMATE INNERVATION IN ALZHEIMERS-DISEASE. NEUROSCIENCE LETTERS , 73 (1) 77 - 80. 10.1016/0304-3940(87)90034-6.

Hardy, J; Crook, R; (2001) Presenilin mutations line up along transmembrane alpha-helices. NEUROSCIENCE LETTERS , 306 (3) 203 - 205. 10.1016/S0304-3940(01)01910-3.

HARDY, J; CROOK, R; PERRY, R; RAGHAVAN, R; ROBERTS, G; (1994) APOE GENOTYPE AND DOWNS-SYNDROME. LANCET , 343 (8903) 979 - 980. 10.1016/S0140-6736(94)90106-6.

HARDY, J; CROOK, R; PRIHAR, G; ROBERTS, G; RAGHAVAN, R; PERRY, R; (1994) SENILE DEMENTIA OF THE LEWY BODY TYPE HAS AN APOLIPOPROTEIN-E EPSILON-4 ALLELE FREQUENCY INTERMEDIATE BETWEEN CONTROLS AND ALZHEIMERS-DISEASE. NEUROSCIENCE LETTERS , 182 (1) 1 - 2. 10.1016/0304-3940(94)90190-2.

Hardy, J; Cullen, K; (2006) Amyloid at the blood vessel wall. NATURE MEDICINE , 12 (7) 756 - 757. 10.1038/nm0706-756.

HARDY, J; DAVIES, D; (1988) ALZHEIMERS-DISEASE. BRITISH JOURNAL OF HOSPITAL MEDICINE , 39 (5) 372 - &.

HARDY, J; DODD, P; (1983) METABOLIC AND FUNCTIONAL-STUDIES ON POSTMORTEM HUMAN-BRAIN. NEUROCHEMISTRY INTERNATIONAL , 5 (3) 253 - 266. 10.1016/0197-0186(83)90027-X.

HARDY, J; DODD, P; OAKLEY, A; KIDD, A; PERRY, R; EDWARDSON, J; (1982) USE OF POSTMORTEM HUMAN SYNAPTOSOMES FOR STUDIES OF METABOLISM AND TRANSMITTER AMINO-ACID RELEASE. NEUROSCIENCE LETTERS , 33 (3) 317 - 322. 10.1016/0304-3940(82)90392-5.

HARDY, J; DODD, P; OAKLEY, A; PERRY, R; EDWARDSON, J; KIDD, A; (1983) METABOLICALLY ACTIVE SYNAPTOSOMES CAN BE PREPARED FROM FROZEN RAT AND HUMAN-BRAIN. JOURNAL OF NEUROCHEMISTRY , 40 (3) 608 - 614. 10.1111/j.1471-4159.1983.tb08024.x.

HARDY, J; DUFF, K; (1993) HETEROGENEITY IN ALZHEIMERS-DISEASE. ANNALS OF MEDICINE , 25 (5) 437 - 440. 10.3109/07853899309147308.

Hardy, J; Duff, K; Hardy, KG; Perez-Tur, J; Hutton, M; (1998) Genetic dissection of Alzheimer's disease and related dementias: Amyloid and its relationship to tau. NATURE NEUROSCIENCE , 1 (5) 355 - 358. 10.1038/1565.

Hardy, J; Goate, A; Owen, M; Rossor, M; (1989) Presenile dementia associated with mosaic trisomy 21 in a patient with a Down syndrome child. Lancet , 2 (8665) 743 - ?.

Hardy, J; Guerreiro, R; (2011) A new way APP mismetabolism can lead to Alzheimer's disease. EMBO MOL MED , 3 (5) 247 - 248. 10.1002/emmm.201100139. Gold open access

Hardy, J; Guerreiro, R; Lovestone, S; (2011) Clusterin as an Alzheimer biomarker. Arch Neurol , 68 (11) 1459 - 1460. 10.1001/archneurol.2011.1000.

Hardy, J; Guerreiro, R; Wray, S; Ferrari, R; Momeni, P; (2011) The Genetics of Alzheimer's Disease and Other Tauopathies. J ALZHEIMERS DIS , 23 S33 - S39.

Hardy, J; Gwinn, K; (2010) Protected to Death. J ALZHEIMERS DIS , 20 (2) 409 - 413. 10.3233/JAD-2010-1416.

Hardy, J; Gwinn-Hardy, K; (1999) Neurodegenerative disease: a different view of diagnosis. MOLECULAR MEDICINE TODAY , 5 (12) 514 - 517. 10.1016/S1357-4310(99)01604-4.

Hardy, J; Gwinn-Hardy, K; (1998) Genetic classification of primary neurodegenerative disease. SCIENCE , 282 (5391) 1075 - 1079. 10.1126/science.282.5391.1075.

HARDY, J; HIGGINS, G; (1992) ALZHEIMERS-DISEASE - THE AMYLOID CASCADE HYPOTHESIS. SCIENCE , 256 (5054) 184 - 185. 10.1126/science.1566067.

HARDY, J; HOULDEN, H; COLLINGE, J; KENNEDY, A; NEWMAN, S; ROSSOR, M; ... DUFF, K; + view all (1993) APOLIPOPROTEIN-E GENOTYPE AND ALZHEIMERS-DISEASE. LANCET , 342 (8873) 737 - 738.

HARDY, J; HUTTON, M; (1995) 2 NEW GENES FOR ALZHEIMERS-DISEASE. TRENDS IN NEUROSCIENCES , 18 (10) 436 - 436. 10.1016/0166-2236(95)90092-6.

HARDY, J; IRVING, N; KESSLING, A; (1989) DOWN ON CHROMOSOME-21. TRENDS IN NEUROSCIENCES , 12 (6) 209 - 210. 10.1016/0166-2236(89)90123-9.

Hardy, J; Israel, A; (1999) Alzheimer's disease - In search of gamma-secretase. NATURE , 398 (6727) 466 - 467. 10.1038/18979.

Hardy, J; Langston, JW; (2004) How many pathways are there to nigral death? ANNALS OF NEUROLOGY , 56 (3) 316 - 318. 10.1002/ana.20257.

Hardy, J; Lees, AJ; (2005) Parkinson's disease: A broken nosology. MOVEMENT DISORDERS , 20 S2 - S4. 10.1002/mds.20532.

Hardy, J; Lewis, P; Revesz, T; Lees, A; Paisan-Ruiz, C; (2009) The genetics of Parkinson's syndromes: a critical review. CURR OPIN GENET DEV , 19 (3) 254 - 265. 10.1016/j.gde.2009.03.008.

Hardy, J; Low, N; Singleton, A; (2008) Whole genome association studies: Deciding when persistence becomes perseveration. AM J MED GENET B , 147B (2) 131 - 133. 10.1002/ajmg.b.30568.

Hardy, J; Low, NC; (2011) Genes and Environment in Psychiatry Winner's Curse or Cure? ARCH GEN PSYCHIAT , 68 (5) 455 - 456.

HARDY, J; MANN, D; WESTER, P; WINBLAD, B; (1986) AN INTEGRATIVE HYPOTHESIS CONCERNING THE PATHOGENESIS AND PROGRESSION OF ALZHEIMERS-DISEASE. NEUROBIOLOGY OF AGING , 7 (6) 489 - 502. 10.1016/0197-4580(86)90086-2.

Hardy, J; Momeni, P; Traynor, BJ; (2006) Frontal temporal dementia: dissecting the aetiology and pathogenesis. BRAIN , 129 830 - 831. 10.1093/brain/awl035.

HARDY, J; MULLAN, M; (1992) ALZHEIMERS-DISEASE - IN SEARCH OF THE SOLUBLE. NATURE , 359 (6393) 268 - 269. 10.1038/359268a0.

Hardy, J; Myers, A; (2007) Genetic variability in expression of proteins and the risk of sporadic neurologic diseases. NEUROLOGY , 68 (9) 632 - 633. 10.1212/01.wnl.0000256793.58438.c4.

Hardy, J; Myers, A; Wavrant-De Vrieze, F; (2004) Problems and Solutions in the Genetic Analysis of Late-Onset Alzheimer's Disease. NEURODEGENERATIVE DISEASES , 1 (4-5) 213 - 217. 10.1159/000080988.

Hardy, J; Orr, H; (2006) The genetics of neurodegenerative diseases. J NEUROCHEM , 97 (6) 1690 - 1699. 10.1111/j.1471-4159.2006.03979.x.

Hardy, J; Perez-Tur, J; Baker, M; Farrer, M; Crook, R; Hutton, M; ... Maraganore, D; + view all (1998) Exclusion of genetic linkage to 4q21-23 and 17q21 in a family with Lewy body parkinsonism. AMERICAN JOURNAL OF MEDICAL GENETICS , 81 (2) 166 - 171.

Hardy, J; Pittman, A; Myers, A; Fung, HC; de Silva, R; Duckworth, J; (2006) Tangle diseases and the tau haplotypes. ALZ DIS ASSOC DIS , 20 (1) 60 - 62.

Hardy, J; Pittman, A; Myers, A; Gwinn-Hardy, K; Fung, HC; de Silva, R; ... Duckworth, J; + view all (2005) Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens. BIOCHEMICAL SOCIETY TRANSACTIONS , 33 582 - 585.

Hardy, J; Revesz, T; (2012) The spread of neurodegenerative disease. N Engl J Med , 366 (22) 2126 - 2128. 10.1056/NEJMcibr1202401.

HARDY, J; ROBERTS, G; (1993) SMOKING AND NEUROGENERATIVE DISEASES. LANCET , 342 (8881) 1238 - 1238. 10.1016/0140-6736(93)92219-J.

Hardy, J; Rogaeva, E; (2013) Motor neuron disease and frontotemporal dementia: sometimes related, sometimes not. Exp Neurol 10.1016/j.expneurol.2013.11.006.

Hardy, J; Scholz, S; Evans, W; Goldfarb, L; Singleton, A; (2006) Prion genotypes in Central America suggest selection for the V129 allele. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS , 141B (1) 33 - 35. 10.1002/ajmg.b.30248.

Hardy, J; Selkoe, DJ; (2002) Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. SCIENCE , 297 (5580) 353 - 356. 10.1126/science.1072994.

Hardy, J; Singleton, A; (2009) CURRENT CONCEPTS Genomewide Association Studies and Human Disease. NEW ENGL J MED , 360 (17) 1759 - 1768. 10.1056/NEJMra0808700.

Hardy, J; Singleton, A; (2008) The HapMap - Charting a course for genetic discovery in neurological diseases. ARCH NEUROL-CHICAGO , 65 (3) 319 - 321.

Hardy, J; Singleton, A; (2007) Reporting and interpretation of genetic variants in cases and controls. NEUROLOGY , 69 (1) 111 - 112. 10.1212/01.wnl.0000265059.56575.a6.

Hardy, J; Singleton, A; (2000) The future of genetic analysis of neurological disorders. NEUROBIOLOGY OF DISEASE , 7 (2) 65 - 69. 10.1006/nbdi.2000.0291.

Hardy, J; Singleton, A; Gwinn-Hardy, K; (2003) Ethnic differences and disease phenotypes. SCIENCE , 300 (5620) 739 - 740. 10.1126/science.300.5620.739.

Hardy, J; Singleton, A; Low, N; (2008) Whole genome association studies: Deciding when persistence becomes perseveration. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics , 147 (2) 131 - 133. 10.1002/ajmg.b.30568.

Hardy, J; Thompson, AJ; (2011) Dissecting the Familial Risk of Multiple Sclerosis. ANN NEUROL , 69 (1) 11 - 12. 10.1002/ana.22353.

Hardy, J; Trabzuni, D; Ryten, M; (2009) Whole genome expression as a quantitative trait. BIOCHEM SOC T , 37 1276 - 1277. 10.1042/BST0371276.

HARDY, J; WESTER, P; BACKSTROM, I; GOTTFRIES, J; ORELAND, L; STENSTROM, A; WINBLAD, B; (1987) THE REGIONAL DISTRIBUTION OF DOPAMINE AND SEROTONIN UPTAKE AND TRANSMITTER CONCENTRATIONS IN THE HUMAN-BRAIN. NEUROCHEMISTRY INTERNATIONAL , 10 (4) 445 - 450. 10.1016/0197-0186(87)90070-2.

HARDY, J; WESTER, P; WINBLAD, B; GEZELIUS, C; BRING, G; ERIKSSON, A; (1985) THE PATIENTS DYING AFTER LONG TERMINAL PHASE HAVE ACIDOTIC BRAINS - IMPLICATIONS FOR BIOCHEMICAL MEASUREMENTS ON AUTOPSY TISSUE. JOURNAL OF NEURAL TRANSMISSION , 61 (3-4) 253 - 264. 10.1007/BF01251916.

Hardy, J; Williams, J; (2010) Identification of Alzheimer Risk Factors Through Whole-Genome Analysis. ARCH NEUROL-CHICAGO , 67 (6) 663 - 664.

Hardy, J; Zetterberg, H; Bogdanovic, N; Winblad, B; Andreasen, N; Cedazo-Minguez, A; Portelius, E; (2014) Pathways to Alzheimer's disease. Journal of Internal Medicine , 275 (3) 296 - 303. 10.1111/joim.12192.

HARDY, JA; GOATE, AM; OWEN, MJ; MULLAN, MJ; ROSSOR, MN; PEARSON, RCA; (1989) MODELING THE OCCURRENCE AND PATHOLOGY OF ALZHEIMERS-DISEASE. NEUROBIOL AGING , 10 (5) 429 - 431.

HARDY, JA; OWEN, MJ; GOATE, AM; JAMES, LA; HAYNES, AR; ROSSOR, MN; ... MULLAN, MJ; + view all (1989) MOLECULAR-GENETICS OF ALZHEIMERS-DISEASE. BIOCHEM SOC T , 17 (1) 75 - 76.

Harhangi, BS; Breteler, MMB; Farrer, MJ; Lincoln, S; Hardy, J; Bonifati, V; ... Oostra, BA; + view all (1999) The Ile93Met mutation in the ubiquitin carboxy-terminal-hydrolase-L1 gene is not observed in European cases with familial Parkinson's disease. Neuroscience Letters , 270 (1) 1 - 4. 10.1016/S0304-3940(99)00465-6.

Harhangi, BS; Farrer, MJ; Lincoln, S; Bonifati, V; Meco, G; De Michele, G; ... Breteler, MMB; + view all (1999) The lle93Met mutation in the ubiquitin carboxy-terminal-hydrolase-L1 gene is not observed in European cases with familial Parkinson's disease. NEUROSCI LETT , 270 (1) 1 - 4.

Harold, D; Abraham, R; Hollingworth, P; Sims, R; Gerrish, A; Hamshere, ML; ... Williams, J; + view all (2013) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet , 45 (6) 712 - ?. 10.1038/ng0613-712a.

Harold, D; Abraham, R; Hollingworth, P; Sims, R; Gerrish, A; Hamshere, ML; ... Williams, J; + view all (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genetics , 41 (10) 1088 -1093. 10.1038/ng.440.

Harold, D; Peirce, T; Moskvina, V; Myers, A; Jones, S; Hollingworth, P; ... Jones, L; + view all (2003) Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease. HUMAN GENETICS , 113 (3) 258 - 267. 10.1007/s00439-003-0960-2.

Harvey, RJ; Ellison, D; Hardy, J; Hutton, M; Rogues, PK; Collinge, J; ... Rossor, MN; + view all (1998) Chromosome 14 familial Alzheimer's disease: the clinical and neuropathological characteristics of a family with a leucine -> serine (L250S) substitution at codon 250 of the presenilin 1 gene. J NEUROL NEUROSUR PS , 64 (1) 44 - 49.

Hayflick, SJ; Kruer, MC; Gregory, A; Haack, TB; Kurian, MA; Houlden, HH; ... Hogarth, P; + view all (2013) Beta-propeller protein-associated neurodegeneration: a new X-linked dominant disorder with brain iron accumulation. Brain 10.1093/brain/awt095.

Henderson, JN; Crook, R; Crook, J; Hardy, J; Onstead, L; Carson-Henderson, L; ... Williams, B; + view all (2002) Apolipoprotein E4 and tau allele frequencies among Choctaw Indians. NEUROSCIENCE LETTERS , 324 (1) , Article PII S0304-3940(02)00150-7. 10.1016/S0304-3940(02)00150-7.

Hernandez, D; Hanson, M; Singleton, A; Gwinn-Hardy, K; Freeman, J; Ravina, B; ... Singleton, A; + view all (2003) Mutation at the SCA17 locus is not a common cause of parkinsonism. PARKINSONISM & RELATED DISORDERS , 9 (6) 317 - 320. 10.1016/S1353-8020(03)00027-0.

Hernandez, D; Paisan Ruiz, C; Crawley, A; Malkani, R; Werner, J; Gwinn-Hardy, K; ... Singleton, A; + view all (2005) The dardarin G 2019 S mutation is a common cause of Parkinson's disease but not other neurodegenerative diseases. Neurosci Lett , 389 (3) 137 - 139. 10.1016/j.neulet.2005.07.044.

Hernandez, DG; Nalls, MA; Moore, M; Chong, S; Dillman, A; Trabzuni, D; ... Cookson, MR; + view all (2012) Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain. Neurobiology of Disease , 47 (1) 20 - 28. 10.1016/j.nbd.2012.03.020. Green and gold open access
file

Hernandez, DG; Nalls, MA; Ylikotila, P; Keller, M; Hardy, JA; Majamaa, K; Singleton, AB; (2012) Genome Wide Assessment of Young Onset Parkinson's Disease from Finland. PLOS ONE , 7 (7) , Article e41859. 10.1371/journal.pone.0041859. Green and gold open access
file

Hersheson, J; Mencacci, NE; Davis, M; MacDonald, N; Trabzuni, D; Ryten, M; ... Houlden, H; + view all (2013) Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia. Ann Neurol , 73 (4) 546 - 553. 10.1002/ana.23832.

Hersheson, J; Mencacci, NE; Davis, M; MacDonald, N; Trabzuni, D; Ryten, M; ... Houlden, H; + view all (2013) Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia. Annals of Neurology , 73 (4) 546 - 553.

Hoglinger, GU; Melhem, NM; Dickson, DW; Sleiman, PMA; Wang, LS; Klei, L; ... PSP Genetics Study Grp,; + view all (2011) Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. NAT GENET , 43 (7) 699 - U125. 10.1038/ng.859.

Holcomb, L; Gordon, MN; McGowan, E; Yu, X; Benkovic, S; Jantzen, P; ... Duff, K; + view all (1998) Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. NATURE MEDICINE , 4 (1) 97 - 100. 10.1038/nm0198-097.

Hollingworth, P; Hamshere, ML; Holmans, PA; O'Donovan, MC; Sims, R; Powell, J; ... Williams, J; + view all (2007) Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS , 144B (7) 841 - 848. 10.1002/ajmg.b.30515.

Hollingworth, P; Harold, D; Sims, R; Gerrish, A; Lambert, JC; Carrasquillo, MM; ... EADI1 Consortium,; + view all (2011) Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. NAT GENET , 43 (5) 429 - +. 10.1038/ng.803.

Holmans, P; Hamshere, M; Hollingworth, P; Rice, F; Tunstall, N; Jones, S; ... Williams, J; + view all (2005) Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS , 135B (1) 24 - 32. 10.1002/ajmg.b.30114.

Holmans, P; Moskvina, V; Jones, L; Sharma, M; International Parkinson's Disease Genomics Consortium,; Vedernikov, A; ... Williams, NM; + view all (2013) A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet , 22 (5) 1039 - 1049. 10.1093/hmg/dds492.

Holmans, P; Moskvina, V; Jones, L; Sharma, M; The International Parkinson's Disease Genomics Consortium (IPDGC),; Vedernikov, A; ... Williams, NM; + view all (2013) A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet 10.1093/hmg/ddt554.

Holmes, MV; Newcombe, P; Hubacek, JA; Sofat, R; Ricketts, SL; Cooper, J; ... Casas, JP; + view all (2011) Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. LANCET , 378 (9791) 584 - 594. 10.1016/S0140-6736(11)60872-6. Gold open access

Holton, P; Ryten, M; Nalls, M; Trabzuni, D; Weale, ME; Hernandez, D; ... Guerreiro, R; + view all (2013) Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Ann Hum Genet , 77 (2) 85 - 105. 10.1111/ahg.12000.

Holton, P; Ryten, M; Trabzuni, D; Hernandez, D; Crehan, H; Gibbs, JR; ... Reiman, EM; + view all (2013) Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci. Annals of Human Genetics , 77 (2) 85 - 105. 10.1111/ahg.12000.

Houlden, H; Baker, M; McGowan, E; Lewis, P; Hutton, M; Crook, R; ... Revesz, T; + view all (2000) Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. ANN NEUROL , 48 (5) 806 - 808.

Houlden, H; Baker, M; Morris, HR; MacDonald, N; Pickering-Brown, S; Adamson, J; ... Hutton, M; + view all (2001) Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. NEUROLOGY , 56 (12) 1702 - 1706.

Houlden, H; Crook, R; Backhovens, H; Prihar, G; Baker, M; Hutton, M; ... Hardy, J; + view all (1998) ApoE genotype is a risk factor in nonpresenilin early-onset Alzheimer's disease families. AM J MED GENET , 81 (1) 117 - 121.

Houlden, H; Crook, R; Dolan, RJ; McLaughlin, J; Revesz, T; Hardy, J; (2001) A novel presenilin mutation (M233V) causing very early onset Alzheimer's disease with Lewy bodies. NEUROSCI LETT , 313 (1-2) 93 - 95.

HOULDEN, H; CROOK, R; DUFF, K; COLLINGE, J; ROQUES, P; ROSSOR, M; HARDY, J; (1993) CONFIRMATION THAT THE APOLIPOPROTEIN E4 ALLELE IS ASSOCIATED WITH LATE-ONSET, FAMILIAL ALZHEIMERS-DISEASE. NEURODEGENERATION , 2 (4) 283 - 286.

HOULDEN, H; CROOK, R; DUFF, K; HUTTON, M; COLLINGE, J; ROQUES, P; ... HARDY, J; + view all (1995) APOLIPOPROTEIN-E ALLELES BUT NEITHER APOLIPOPROTEIN-B NOR APOLIPOPROTEIN AI/CIII ALLELES ARE ASSOCIATED WITH LATE-ONSET, FAMILIAL ALZHEIMERS-DISEASE. NEUROSCI LETT , 188 (3) 202 - 204.

HOULDEN, H; CROOK, R; HARDY, J; ROQUES, P; COLLINGE, J; ROSSER, M; (1994) CONFIRMATION THAT FAMILIAL CLUSTERING AND AGE-OF-ONSET IN LATE-ONSET ALZHEIMERS-DISEASE ARE DETERMINED AT THE APOLIPOPROTEIN-E LOCUS. NEUROSCI LETT , 174 (2) 222 - 224.

Houlden, H; Lincoln, S; Farrer, M; Cleland, PG; Hardy, J; Orrell, RW; (2003) Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic. NEUROLOGY , 61 (10) 1423 - 1426.

Houlden, H; Rizzu, P; Stevens, M; de Knijff, P; van Duijn, CM; van Swieten, JC; ... Hardy, J; + view all (1999) Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations. NEUROSCI LETT , 260 (3) 193 - 195.

Houlden, H; Schneider, SA; Paudel, R; Melchers, A; Schwingenschuh, P; Edwards, M; ... Bhatia, KP; + view all (2010) THAP1 mutations (DYT6) are an additional cause of early-onset dystonia. NEUROLOGY , 74 (10) 846 - 850.

Huang, L; Li, Y; Singleton, AB; Hardy, JA; Abecasis, G; Rosenberg, NA; Scheet, P; (2009) Genotype-Imputation Accuracy across Worldwide Human Populations. AM J HUM GENET , 84 (2) 235 - 250. 10.1016/j.ajhg.2009.01.013.

Hudson, G; Nalls, M; Evans, JR; Breen, DP; Winder-Rhodes, S; Morrison, KE; ... Chinnery, PF; + view all (2013) Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease. Neurology , 80 (22) 2042 - 2048. 10.1212/WNL.0b013e318294b434.

Huey, ED; Ferrari, R; Moreno, JH; Jensen, C; Morris, CM; Potocnik, F; ... Momeni, P; + view all (2012) FUS and TDP43 genetic variability in FTD and CBS. NEUROBIOLOGY OF AGING , 33 (5) , Article ARTN 1016.e9. 10.1016/j.neurobiolaging.2011.08.004.

Huey, ED; Grafman, J; Wassermann, EM; Pietrini, P; Tierney, MC; Ghetti, B; ... Momeni, P; + view all (2006) Characteristics of frontotemporal dementia patients with a progranulin mutation. ANNALS OF NEUROLOGY , 60 (3) 374 - 380. 10.1002/ana.20969.

Hutton, M; Busfield, F; Wragg, M; Crook, R; PerezTur, J; Clark, RF; ... Goate, A; + view all (1996) Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease. NEUROREPORT , 7 (3) 801 - 805.

Hutton, M; Hardy, J; (1997) The presenilins and Alzheimer's disease. HUMAN MOLECULAR GENETICS , 6 (10) 1639 - 1646. 10.1093/hmg/6.10.1639.

Hutton, M; Lendon, CL; Rizzu, P; Baker, M; Froelich, S; Houlden, H; ... Heutink, P; + view all (1998) Association of missense and 5 '-splice-site mutations in tau with the inherited dementia FTDP-17. NATURE , 393 (6686) 702 - 705.

International Stroke Genetics Consortium,; Wellcome Trust Case-Control Consortium 2,; (2010) Failure to validate association between 12p13 variants and ischemic stroke. N Engl J Med , 362 (16) 1547 - 1550. 10.1056/NEJMc0910050.

IRVING, N; HARDY, J; BAHARY, N; FRIEDMAN, J; BROWN, S; (1989) THE ALPHA-2 CHAIN OF TYPE-1 COLLAGEN DOES NOT MAP TO MOUSE CHROMOSOME-16 BUT MAPS CLOSE TO THE MET PROTO-ONCOGENE ON MOUSE CHROMOSOME-6. CYTOGENETICS AND CELL GENETICS , 50 (2-3) 121 - 122. 10.1159/000132737.

IRVING, N; HARDY, J; BROWN, S; (1991) THE MULTIPOINT GENETIC-MAPPING OF MOUSE CHROMOSOME-16. GENOMICS , 9 (2) 386 - 389. 10.1016/0888-7543(91)90271-F.

Jakobsson, M; Scholz, SW; Scheet, P; Gibbs, JR; VanLiere, JM; Fung, HC; ... Singleton, AB; + view all (2008) Genotype, haplotype and copy-number variation in worldwide human populations. NATURE , 451 (7181) 998 - 1003. 10.1038/nature06742.

JEFFERYS, J; MITCHELL, P; OHARA, L; TILEY, C; HARDY, J; JORDAN, S; ... WADSWORTH, J; + view all (1991) EXVIVO RELEASE OF GABA FROM TETANUS TOXIN-INDUCED CHRONIC EPILEPTIC FOCI DECREASED DURING THE ACTIVE SEIZURE PHASE. NEUROCHEMISTRY INTERNATIONAL , 18 (3) 373 - 379. 10.1016/0197-0186(91)90169-E.

Jenner, P; Morris, HR; Robbins, TW; Goedert, M; Hardy, J; Ben-Shlomo, Y; ... Grp, PUKD; + view all (2013) Parkinson's Disease - the Debate on the Clinical Phenomenology, Aetiology, Pathology and Pathogenesis. JOURNAL OF PARKINSONS DISEASE , 3 (1) 1 - 11. 10.3233/JPD-130175.

Johnson, J; Hague, SM; Hanson, M; Gibson, A; Wilson, KE; Evans, EW; ... Singleton, AB; + view all (2004) SNCA multiplication is not a common cause of Parkinson disease or dementia with Lewy bodies. NEUROLOGY , 63 (3) 554 - 556.

Johnson, J; Ostojic, J; Lannfelt, L; Glaser, A; Basun, H; Rogaeva, E; ... Singleton, A; + view all (2004) No evidence for tau duplications in frontal temporal dementia families showing genetic linkage to the tau locus in which tau mutations have not been found. NEUROSCIENCE LETTERS , 363 (2) 99 - 101. 10.1016/j.neulet.2004.03.070.

Johnson, JO; Pioro, EP; Boehringer, A; Chia, R; Feit, H; Renton, AE; ... Traynor, BJ; + view all (2014) Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis. Nat Neurosci 10.1038/nn.3688.

Johnson, JO; Renton, AE; Pliner, HA; Marangi, G; Traynor, BJ; Pioro, EP; ... Sabatelli, M; + view all (2014) Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis. Nature Neuroscience , 17 (5) 664 - 666. 10.1038/nn.3688.

Jones, L; Holmans, PA; Hamshere, ML; Harold, D; Moskvina, V; Ivanov, D; ... Williams, J; + view all (2010) Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease. PLOS ONE , 5 (11) , Article e13950. 10.1371/journal.pone.0013950. Green and gold open access
file

Kalinderi, K; Bostantjopoulou, S; Paisan-Ruiz, C; Katsarou, Z; Hardy, J; Fidani, L; (2009) Complete screening for glucocerebrosidase mutations in Parkinson disease patients from Greece. NEUROSCI LETT , 452 (2) 87 - 89. 10.1016/j.neulet.2009.01.029.

Kamboh, MI; Aston, CE; Perez-Tur, J; Kokmen, E; Ferrell, RE; Hardy, J; DeKosky, ST; (1999) A novel mutation in the apolipoprotein E gene (APOE*4 Pittsburgh) is associated with the risk of late-onset Alzheimer's disease. NEUROSCIENCE LETTERS , 263 (2-3) 129 - 132. 10.1016/S0304-3940(99)00129-9.

Kara, E; Bras, J; Wood, NW; Hardy, J; Houlden, H; Hernandez, D; ... Bostantjopoulou, S; + view all (2014) Assessment of Parkinson's disease risk loci in Greece. Neurobiology of Aging , 35 (2) 10.1016/j.neurobiolaging.2013.07.011.

Kara, E; Hardy, J; Houlden, H; (2013) The pallidopyramidal syndromes: Nosology, aetiology and pathogenesis. Current Opinion in Neurology , 26 (4) 381 - 394. 10.1097/WCO.0b013e3283632e83. Green and gold open access
file

Kara, E; Hardy, J; Houlden, H; (2013) The pallidopyramidal syndromes: nosology, aetiology and pathogenesis. Curr Opin Neurol , 26 (4) 381 - 394. 10.1097/WCO.0b013e3283632e83.

Kara, E; Kiely, AP; Proukakis, C; Giffin, N; Love, S; Hehir, J; ... Houlden, H; + view all (2014) A 6.4 Mb Duplication of the α-Synuclein Locus Causing Frontotemporal Dementia and Parkinsonism: Phenotype-Genotype Correlations. JAMA Neurol 10.1001/jamaneurol.2014.994.

Kara, E; Lewis, PA; Ling, H; Proukakis, C; Houlden, H; Hardy, J; (2013) α-Synuclein mutations cluster around a putative protein loop. Neurosci Lett , 546 67 - 70. 10.1016/j.neulet.2013.04.058. Green and gold open access
file

Kara, E; Lewis, PA; Ling, H; Proukakis, C; Houlden, H; Hardy, J; (2013) α-Synuclein mutations cluster around a putative protein loop. Neuroscience Letters , 546 67 - 70.

Kara, E; Ling, H; Pittman, AM; Shaw, K; de Silva, R; Simone, R; ... Revesz, T; + view all (2012) The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features. Neurobioly of Aging , 33 (9) 2231.e7 - 2231.e14. 10.1016/j.neurobiolaging.2012.04.006. Green and gold open access
file

Kara, E; Xiromerisiou, G; Spanaki, C; Bozi, M; Koutsis, G; Panas, M; ... Singleton, AB; + view all (2013) Assessment of Parkinson's disease risk loci in Greece. Neurobiol Aging 10.1016/j.neurobiolaging.2013.07.011.

Karran, E; Hardy, J; (2014) A Critique of the Drug Discovery and Phase 3 Clinical Programmes targeting the Amyloid Hypothesis for Alzheimer's disease. Ann Neurol , 76 (2) pp. 185-205. 10.1002/ana.24188. Green and gold open access
file

Karran, E; Hardy, J; (2014) Antiamyloid therapy for Alzheimer's disease--are we on the right road? N Engl J Med , 370 (4) 377 - 378. 10.1056/NEJMe1313943.

Keenan, BT; Shulman, JM; Chibnik, LB; Raj, T; Tran, D; Sabuncu, MR; ... Neuroimaging, AD; + view all (2012) A coding variant in CR1 interacts with APOE-?4 to influence cognitive decline. HUMAN MOLECULAR GENETICS , 21 (10) 2377 - 2388. 10.1093/hmg/dds054.

Kehoe, P; Wavrant-De Vrieze, F; Crook, R; Wu, WS; Holmans, P; Fenton, I; ... Owen, MJ; + view all (1999) A full genome scan for late onset Alzheimer's disease. HUMAN MOLECULAR GENETICS , 8 (2) 237 - 245. 10.1093/hmg/8.2.237.

Keller, MF; Saad, M; Bras, J; Bettella, F; Nicolaou, N; Simón-Sánchez, J; ... Wellcome Trust Case Control Consortium 2 (WTCCC2),; + view all (2012) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum Mol Genet , 21 (22) 4996 - 5009. 10.1093/hmg/dds335.

Keller, MF; Saad, M; Bras, J; Bettella, F; Nicolaou, N; Simon-Sanchez, J; ... WTCCC2,; + view all (2013) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinsons disease (vol 22, pg 1696, 2013). HUMAN MOLECULAR GENETICS , 22 (14) 2973 - 2973. 10.1093/hmg/ddt199.

Keller, MF; Saad, M; Bras, J; Bettella, F; Nicolaou, N; Simon-Sanchez, J; ... WTCCC2,; + view all (2013) Using genome-wide complex trait analysis to quantify missing heritability in Parkinsons disease (vol 21, pg 4996, 2012). HUMAN MOLECULAR GENETICS , 22 (8) 1696 - 1696. 10.1093/hmg/ddt030.

KENNEDY, AM; NEWMAN, S; MCCADDON, A; BALL, J; ROQUES, P; MULLAN, M; ... ROSSOR, MN; + view all (1993) FAMILIAL ALZHEIMERS-DISEASE - A PEDIGREE WITH A MIS-SENSE MUTATION IN THE AMYLOID PRECURSOR PROTEIN GENE (AMYLOID PRECURSOR PROTEIN 717 VALINE -] GLYCINE). BRAIN , 116 309 - 324.

Khan, TA; Shah, T; Prieto, D; Zhang, W; Price, J; Fowkes, GR; ... Casas, JP; + view all (2013) Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. Int J Epidemiol , 42 (2) 475 - 492. 10.1093/ije/dyt034.

Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; ... Holton, JL; + view all (2013) Clinical and neuropathological features of synucleinopathy associated with G51D SNCA mutation. MOVEMENT DISORDERS , 28 S277 - S277.

Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; ... Holton, JL; + view all (2013) α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy? Acta Neuropathologica , 125 (5) 753 - 769. 10.1007/s00401-013-1096-7. Green and gold open access
filefilefile

Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; ... Holton, JL; + view all (2013) α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy? Acta neuropathologica , 125 (5) 753 - 769. 10.1007/s00401-013-1096-7.

KING, A; HOULDEN, H; HARDY, J; LANE, R; CHANCELLOR, A; DEBELLEROCHE, J; (1993) ABSENCE OF LINKAGE BETWEEN CHROMOSOME-21 LOCI AND FAMILIAL AMYOTROPHIC-LATERAL-SCLEROSIS. J MED GENET , 30 (4) 318 - 318.

Klebe, S; Golmard, JL; Nalls, MA; Saad, M; Singleton, AB; Bras, JM; ... Wood, NW; + view all (2013) The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism. Journal of Neurology, Neurosurgery and Psychiatry , 84 (6) 666 - 673. 10.1136/jnnp-2012-304475. Green and gold open access
file

Kleinberger, G; Yamanishi, Y; Suárez-Calvet, M; Czirr, E; Lohmann, E; Cuyvers, E; ... Haass, C; + view all (2014) TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Sci Transl Med , 6 (243) 243ra86 - ?. 10.1126/scitranslmed.3009093.

Ko, LW; Mehta, ND; Farrer, M; Easson, C; Hussey, J; Yen, S; ... Yen, SHC; + view all (2000) Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein. JOURNAL OF NEUROCHEMISTRY , 75 (6) 2546 - 2554. 10.1046/j.1471-4159.2000.0752546.x.

Kojovic, M; Sheerin, UM; Rubio-Agusti, I; Saha, A; Bras, J; Gibbons, V; ... Bhatia, KP; + view all (2012) Young-onset parkinsonism due to homozygous duplication of α-synuclein in a consanguineous family. Mov Disord , 27 (14) pp. 1829-1830. 10.1002/mds.25199. Green and gold open access
file

Kruer, MC; Hayflick, SJ; Paudel, R; Kara, E; Foltynie, T; Lees, A; ... Gregory, A; + view all (2012) Analysis of ATP13A2 in large neurodegeneration with brain iron accumulation (NBIA) and dystonia-parkinsonism cohorts. Neuroscience Letters , 523 (1) 35 - 38. 10.1016/j.neulet.2012.06.036.

Kruer, MC; Paisan-Ruiz, C; Boddaert, N; Yoon, MY; Hama, H; Gregory, A; ... Hayflick, SJ; + view all (2010) Defective FA2H Leads to a Novel Form of Neurodegeneration with Brain Iron Accumulation (NBIA). ANN NEUROL , 68 (5) 611 - 618. 10.1002/ana.22122.

Kruer, MC; Paudel, R; Wagoner, W; Sanford, L; Kara, E; Gregory, A; ... Houlden, H; + view all (2012) Analysis of ATP13A2 in large neurodegeneration with brain iron accumulation (NBIA) and dystonia-parkinsonism cohorts. Neurosci Lett , 523 (1) 35 - 38. 10.1016/j.neulet.2012.06.036.

Kumar, A; Gibbs, JR; Beilina, A; Dillman, A; Kumaran, R; Trabzuni, D; ... Cookson, MR; + view all (2013) Age-associated changes in gene expression in human brain and isolated neurons. Neurobiol Aging , 34 (4) 1199 - 1209. 10.1016/j.neurobiolaging.2012.10.021.

Kumar, A; Gibbs, JR; Beilina, A; Dillman, A; Kumaran, R; Traynor, BJ; ... Smith, C; + view all (2013) Age-associated changes in gene expression in human brain and isolated neurons. Neurobiology of Aging , 34 (4) 1199 - 1209. 10.1016/j.neurobiolaging.2012.10.021.

Kumar-Singh, S; Pirici, D; McGowan, E; Serneels, S; Ceuterick, C; Hardy, J; ... Van Broeckhoven, C; + view all (2005) Dense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls. AMERICAN JOURNAL OF PATHOLOGY , 167 (2) 527 - 543. 10.1016/S0002-9440(10)62995-1.

Kumaran, R; Vandrovcova, J; Luk, C; Sharma, S; Renton, A; Wood, NW; ... Bandopadhyay, R; + view all (2009) Differential DJ-1 gene expression in Parkinson's disease. NEUROBIOL DIS , 36 (2) 393 - 400. 10.1016/j.nbd.2009.08.011.

Kwok, JBJ; Taddei, K; Hallupp, M; Fisher, C; Brooks, WS; Broe, GA; ... Martins, RN; + view all (1997) Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype. NEUROREPORT , 8 (6) 1537 - 1542. 10.1097/00001756-199704140-00043.

Lahiri, DK; Ge, YW; Maloney, B; Wavrant-De Vrieze, F; Hardy, J; (2005) Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease. NEUROBIOLOGY OF AGING , 26 (10) 1329 - 1341. 10.1016/j.neurobiolaging.2004.11.005.

Lambert, JC; Araria-Goumidi, L; Myllykangas, L; Ellis, C; Wang, JC; Bullido, MJ; ... Chartier-Harlin, MC; + view all (2002) Contribution of APOE promoter polymorphisms to Alzheimer's disease risk. NEUROLOGY , 59 (1) 59 - 66.

Lambert, JC; Berr, C; Pasquier, F; Delacourte, A; Frigard, B; Cottel, D; ... Chartier-Harlin, MC; + view all (1998) Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease. HUMAN MOLECULAR GENETICS , 7 (9) 1511 - 1516. 10.1093/hmg/7.9.1511.

Lambert, JC; Goumidi, L; Wavrant-De Vrieze, F; Frigard, B; Harris, JM; Cummings, A; ... Chartier-Harlin, MC; + view all (2000) The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease. HUMAN MOLECULAR GENETICS , 9 (15) 2275 - 2280.

Lambert, JC; Ibrahim-Verbaas, CA; Harold, D; Naj, AC; Sims, R; Bellenguez, C; ... Amouyel, P; + view all (2013) Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet 10.1038/ng.2802.

Lambert, JC; PerezTur, J; Dupire, MJ; Galasko, D; Mann, D; Amouyel, P; ... ChartierHarlin, MC; + view all (1997) Distortion of allelic expression of apolipoprotein E in Alzheimer's disease. HUMAN MOLECULAR GENETICS , 6 (12) 2151 - 2154. 10.1093/hmg/6.12.2151.

Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ; ... NHLBI Grand Opportunity Exome Sequencing Project,; + view all