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Number of items: 44.

2023

Cardoso, M Helena; Hall, Michael J; Burgoyne, Thomas; Fale, Pedro; Storm, Tina; Escrevente, Cristina; Antas, Pedro; ... Futter, Clare E; + view all (2023) Impaired Lysosome Reformation in Chloroquine-Treated Retinal Pigment Epithelial Cells. Investigative Ophthalmology & Visual Science , 64 (11) , Article 10. 10.1167/iovs.64.11.10. Green open access
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2022

Alves, LS; Marques, ARA; Padrão, N; Carvalho, FA; Ramalho, J; Lopes, CS; Soares, MIL; ... Vieira, OV; + view all (2022) Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis. Journal of Cell Science , 135 (5) , Article jcs254631. 10.1242/jcs.254631. Green open access
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2021

Eden, ER; Futter, CE; (2021) Membrane trafficking: Retrofusion as an escape route out of the endosome. Current Biology , 31 (17) R1037-R1040. 10.1016/j.cub.2021.07.055. Green open access
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Escrevente, C; Falcao, AS; Hall, MJ; Lopes-da-Silva, M; Antas, P; Mesquita, MM; Ferreira, IS; ... Seabra, MC; + view all (2021) Formation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction. Investigative Ophthalmology & Visual Science , 62 (9) , Article 39. 10.1167/iovs.62.9.39. Green open access
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2020

Jones, S; King, PJ; Antonescu, CN; Sugiyama, MG; Bhamra, A; Surinova, S; Angelopoulos, N; ... Hochhauser, D; + view all (2020) Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation. Scientific Reports , 10 , Article 663. 10.1038/s41598-019-57153-9. Green open access
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Meschede, I; Ovenden, N; Seabra, M; Futter, C; Votruba, M; Cheetham, M; Burgoyne, T; (2020) Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1. Proceedings of the National Academy of Sciences of the United States of America (PNAS) , 117 (27) pp. 15684-15693. 10.1073/pnas.2000304117. Green open access
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Meschede, IP; Burgoyne, T; Tolmachova, T; Seabra, MC; Futter, CE; (2020) Chronically shortened rod outer segments accompany photoreceptor cell death in Choroideremia. PLOS ONE , 15 (11) , Article e0242284. 10.1371/journal.pone.0242284. Green open access
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Storm, T; Burgoyne, T; Futter, CE; (2020) Membrane trafficking in the retinal pigment epithelium at a glance. Journal of Cell Science , 133 (16) , Article jcs238279. 10.1242/jcs.238279. Green open access
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2019

Enrich, C; Rentero, C; Grewal, T; Futter, CE; Eden, ER; (2019) Cholesterol Overload: Contact Sites to the Rescue! Contact , 2 10.1177/2515256419893507. Green open access
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Hayes, MJ; Burgoyne, T; Wavre-Shapton, ST; Tolmachova, T; Seabra, MC; Futter, CE; (2019) Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease. Investigative Ophthalmology & Visual Science , 60 (7) pp. 2515-2524. 10.1167/iovs.19-26784. Green open access
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Höglinger, D; Burgoyne, T; Sanchez-Heras, E; Hartwig, P; Colaco, A; Newton, J; Futter, CE; ... Eden, ER; + view all (2019) NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress. Nature Communications , 10 (1) , Article 4276. 10.1038/s41467-019-12152-2. Green open access
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Storm, T; Burgoyne, T; Dunaief, JL; Christensen, EI; Futter, C; Nielsen, R; (2019) Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration. Investigative Ophthalmology & Visual Science , 60 (1) pp. 322-330. 10.1167/iovs.18-25667. Green open access
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Toms, M; Burgoyne, T; Tracey-White, D; Richardson, R; Dubis, AM; Webster, AR; Futter, C; (2019) Phagosomal and mitochondrial alterations in RPE may contribute to KCNJ13 retinopathy. Scientific Reports , 9 , Article 3793. 10.1038/s41598-019-40507-8. Green open access
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2018

Burgoyne, T; Lane, A; Laughlin, WE; Cheetham, ME; Futter, CE; (2018) Correlative light and immuno-electron microscopy of retinal tissue cryostat sections. PLoS One , 13 (1) , Article e0191048. 10.1371/journal.pone.0191048. Green open access
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Monypenny, J; Milewicz, H; Flores-Borja, F; Weitsman, G; Cheung, A; Chowdhury, R; Burgoyne, T; ... Ng, T; + view all (2018) ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation. Cell Reports , 24 (3) pp. 630-641. 10.1016/j.celrep.2018.06.066. Green open access
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Wong, LH; Eden, ER; Futter, CE; (2018) Roles for ER : endosome membrane contact sites in ligand-stimulated intraluminal vesicle formation. [Review]. Biochemical Society Transactions 10.1042/BST20170432. Green open access
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2017

Agrawal, SA; Burgoyne, T; Eblimit, A; Bellingham, J; Parfitt, DA; Lane, A; Nichols, R; ... Cheetham, ME; + view all (2017) REEP6 Deficiency Leads to Retinal Degeneration through Disruption of ER Homeostasis and Protein Trafficking. Human Molecular Genetics , 26 (14) pp. 2667-2677. 10.1093/hmg/ddx149. Green open access
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Dragoni, S; Hudson, N; Kenny, B-A; Burgoyne, T; McKenzie, JA; Gill, Y; Blaber, R; ... Turowski, P; + view all (2017) Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions. J Immunol , 198 (10) pp. 4074-4085. 10.4049/jimmunol.1600823. Green open access
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Kilpatrick, BS; Eden, ER; Hockey, LN; Yates, E; Futter, CE; Patel, S; (2017) An Endosomal NAADP-Sensitive Two-Pore Ca(2+) Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling. Cell Rep , 18 (7) pp. 1636-1645. 10.1016/j.celrep.2017.01.052. Green open access
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Melo, E; Oertle, P; Trepp, C; Meistermann, H; Burgoyne, T; Sborgi, L; Cabrera, AC; ... Iacone, R; + view all (2017) HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model. EBioMedicine 10.1016/j.ebiom.2017.12.011. Green open access
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Stefan, CJ; Trimble, WS; Grinstein, S; Drin, G; Reinisch, K; De Camilli, P; Cohen, S; ... McBride, HM; + view all (2017) Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers. BMC Biology , 15 (1) , Article 102. 10.1186/s12915-017-0432-0. Green open access
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Tomas, A; Jones, S; Vaughan, SO; Hochhauser, D; Futter, CE; (2017) Stress-specific p38 MAP kinase activation is sufficient to drive EGF receptor endocytosis but not nuclear translocation. Journal of Cell Science , 130 (15) pp. 2481-2490. 10.1242/jcs.202358. Green open access
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Willén, K; Edgar, JR; Hasegawa, T; Tanaka, N; Futter, CE; Gouras, GK; (2017) Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A. Molecular Neurodegeneration , 12 , Article 61. 10.1186/s13024-017-0203-y. Green open access
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2016

Burgoyne, T; Meschede, IP; Futter, CE; (2016) New light on photoreceptor renewal. Cell Cycle , 15 (11) pp. 1389-1390. 10.1080/15384101.2016.1164579. Green open access
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Eden, ER; Sanchez-Heras, E; Tsapara, A; Sobota, A; Levine, TP; Futter, CE; (2016) Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport. Developmental Cell , 37 (5) pp. 473-483. 10.1016/j.devcel.2016.05.005. Green open access
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Futter, CE; Cutler, DF; (2016) Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation. Journal of Cell Biology , 214 (3) pp. 245-247. 10.1083/jcb.201607023. Green open access
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Zhang, R; Fruhwirth, GO; Coban, O; Barrett, JE; Burgoyne, T; Lee, SH; Simonson, PD; ... Selvin, PR; + view all (2016) Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-Resolution Microscopy. ACS Nano , 11 (1) pp. 249-257. 10.1021/acsnano.6b05356. Green open access
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2015

Burgoyne, T; O'Connor, MN; Seabra, MC; Cutler, DF; Futter, CE; (2015) Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL. J Cell Sci , 128 (7) 1400 - 1407. 10.1242/jcs.164400. Green open access
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Edgar, JR; Willen, K; Gouras, GK; Futter, CE; (2015) ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-beta accumulation. JOURNAL OF CELL SCIENCE , 128 (14) pp. 2520-2528. 10.1242/jcs.170233. Green open access
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Futter, CE; Tomas, A; Vaughan, SO; Burgoyne, T; Sorkin, A; Hochhauser, D; (2015) WASH and Tsg101/ALIX-dependent diversion of stress-internalised EGFR from the canonical endocytic pathway. Nature Communications , 6 , Article 7324. 10.1038/ncomms8324. Green open access
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Georgiannakis, A; Burgoyne, T; Lueck, K; Futter, C; Greenwood, J; Moss, SE; (2015) Retinal pigment epithelial cells mitigate the effects of complement attack by endocytosis of C5b-9. Journal of Immunology , 195 (7) pp. 3382-3389. 10.4049/jimmunol.1500937. Green open access
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Hidalgo-de-Quintana, J; Schwarz, N; Meschede, IP; Stern-Schneider, G; Powner, MB; Morrison, EE; Futter, CE; ... van der Spuy, J; + view all (2015) The Leber Congenital Amaurosis Protein AIPL1 and EB Proteins Co-Localize at the Photoreceptor Cilium. PLoS One , 10 (3) , Article e0121440 . 10.1371/journal.pone.0121440. Green open access
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Hockey, LN; Kilpatrick, BS; Eden, E; Lin-Moshier, Y; Brailoiu, GC; Brailoiu, E; Futter, CE; ... Patel, S; + view all (2015) Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by two-pore channel 2 inhibition. Journal of Cell Science , 128 pp. 232-238. 10.1242/​jcs.164152. Green open access
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Vaughan, SOK; (2015) The relationship between stress-induced endocytosis of epidermal growth factor receptor and cell survival. Doctoral thesis , UCL (University College London).

Wavre-Shapton, ST; Calvi, AA; Turmaine, M; Seabra, MC; Cutler, DF; Futter, CE; Mitchison, HM; (2015) Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease). Human Molecular Genetics , 24 (24) pp. 7060-7074. 10.1093/hmg/ddv406. Green open access
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2014

Edgar, JR; Eden, ER; Futter, CE; (2014) Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles. Traffic , 15 (2) 197- 211. 10.1111/tra.12139. Green open access
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Hudson, N; Powner, MB; Sarker, MH; Burgoyne, T; Campbell, M; Ockrim, ZK; Martinelli, R; ... Turowski, P; + view all (2014) Differential apicobasal VEGF signaling at vascular blood-neural barriers. Dev Cell , 30 (5) 541 - 552. 10.1016/j.devcel.2014.06.027. Green open access
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Wavre-Shapton, ST; Meschede, IP; Seabra, MC; Futter, CE; (2014) Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium. J Cell Sci , 127 pp. 3852-3861. 10.1242/jcs.154757. Green open access
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2013

Burgoyne, T; Jolly, R; Martin-Martin, B; Seabra, MC; Piccirillo, R; Schiaffino, MV; Futter, CE; (2013) Expression of OA1 limits the fusion of a subset of MVBs with lysosomes; a mechanism likely involved in the initial biogenesis of melanosomes. Journal of Cell Science , 126 (22) 10.1242/jcs.128561. Green open access
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Wavre-Shapton, ST; Tolmachova, T; da Silva, ML; Futter, CE; Seabra, MC; (2013) Conditional ablation of the choroideremia gene causes age-related changes in mouse retinal pigment epithelium. PLoS One , 8 (2) , Article 57769. 10.1371/journal.pone.0057769. Green open access
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2010

Carvou, Nicolas; Holic, Roman; Li, Michelle; Futter, Clare; Skippen, Alison; Cockcroft, Shamshad; (2010) Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPβ is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum. Journal of Cell Science , 123 (8) pp. 1262-1273. 10.1242/jcs.061986. Green open access
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2006

Razi, M; Futter, CE; (2006) Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation. MOL BIOL CELL , 17 (8) 3469 - 3483. 10.1091/mbc.E05-11-1054. Green open access
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2004

Futter, CE; Ramalho, JS; Jaissle, GB; Seeliger, MW; Seabra, MC; (2004) The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells. MOL BIOL CELL , 15 (5) 2264 - 2275. 10.1091/mbc.E03-10-0772. Green open access
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Tomas, A; Futter, C; Moss, SE; (2004) Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis. JOURNAL OF CELL BIOLOGY , 165 (6) pp. 813-822. 10.1083/jcb.200311054. Green open access
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This list was generated on Sun Mar 24 08:55:47 2024 GMT.