Browse by UCL people
Group by: Type | Date
Number of items: 44.
2023
Cardoso, M Helena;
Hall, Michael J;
Burgoyne, Thomas;
Fale, Pedro;
Storm, Tina;
Escrevente, Cristina;
Antas, Pedro;
... Futter, Clare E; + view all
(2023)
Impaired Lysosome Reformation in Chloroquine-Treated Retinal Pigment Epithelial Cells.
Investigative Ophthalmology & Visual Science
, 64
(11)
, Article 10. 10.1167/iovs.64.11.10.
|
2022
Alves, LS;
Marques, ARA;
Padrão, N;
Carvalho, FA;
Ramalho, J;
Lopes, CS;
Soares, MIL;
... Vieira, OV; + view all
(2022)
Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis.
Journal of Cell Science
, 135
(5)
, Article jcs254631. 10.1242/jcs.254631.
|
2021
Eden, ER;
Futter, CE;
(2021)
Membrane trafficking: Retrofusion as an escape route out of the endosome.
Current Biology
, 31
(17)
R1037-R1040.
10.1016/j.cub.2021.07.055.
|
Escrevente, C;
Falcao, AS;
Hall, MJ;
Lopes-da-Silva, M;
Antas, P;
Mesquita, MM;
Ferreira, IS;
... Seabra, MC; + view all
(2021)
Formation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction.
Investigative Ophthalmology & Visual Science
, 62
(9)
, Article 39. 10.1167/iovs.62.9.39.
|
2020
Jones, S;
King, PJ;
Antonescu, CN;
Sugiyama, MG;
Bhamra, A;
Surinova, S;
Angelopoulos, N;
... Hochhauser, D; + view all
(2020)
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Scientific Reports
, 10
, Article 663. 10.1038/s41598-019-57153-9.
|
Meschede, I;
Ovenden, N;
Seabra, M;
Futter, C;
Votruba, M;
Cheetham, M;
Burgoyne, T;
(2020)
Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
, 117
(27)
pp. 15684-15693.
10.1073/pnas.2000304117.
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Meschede, IP;
Burgoyne, T;
Tolmachova, T;
Seabra, MC;
Futter, CE;
(2020)
Chronically shortened rod outer segments accompany photoreceptor cell death in Choroideremia.
PLOS ONE
, 15
(11)
, Article e0242284. 10.1371/journal.pone.0242284.
|
Storm, T;
Burgoyne, T;
Futter, CE;
(2020)
Membrane trafficking in the retinal pigment epithelium at a glance.
Journal of Cell Science
, 133
(16)
, Article jcs238279. 10.1242/jcs.238279.
|
2019
Enrich, C;
Rentero, C;
Grewal, T;
Futter, CE;
Eden, ER;
(2019)
Cholesterol Overload: Contact Sites to the Rescue!
Contact
, 2
10.1177/2515256419893507.
|
Hayes, MJ;
Burgoyne, T;
Wavre-Shapton, ST;
Tolmachova, T;
Seabra, MC;
Futter, CE;
(2019)
Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease.
Investigative Ophthalmology & Visual Science
, 60
(7)
pp. 2515-2524.
10.1167/iovs.19-26784.
|
Höglinger, D;
Burgoyne, T;
Sanchez-Heras, E;
Hartwig, P;
Colaco, A;
Newton, J;
Futter, CE;
... Eden, ER; + view all
(2019)
NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress.
Nature Communications
, 10
(1)
, Article 4276. 10.1038/s41467-019-12152-2.
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Storm, T;
Burgoyne, T;
Dunaief, JL;
Christensen, EI;
Futter, C;
Nielsen, R;
(2019)
Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration.
Investigative Ophthalmology & Visual Science
, 60
(1)
pp. 322-330.
10.1167/iovs.18-25667.
|
Toms, M;
Burgoyne, T;
Tracey-White, D;
Richardson, R;
Dubis, AM;
Webster, AR;
Futter, C;
(2019)
Phagosomal and mitochondrial alterations in RPE may contribute to KCNJ13 retinopathy.
Scientific Reports
, 9
, Article 3793. 10.1038/s41598-019-40507-8.
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2018
Burgoyne, T;
Lane, A;
Laughlin, WE;
Cheetham, ME;
Futter, CE;
(2018)
Correlative light and immuno-electron microscopy of retinal tissue cryostat sections.
PLoS One
, 13
(1)
, Article e0191048. 10.1371/journal.pone.0191048.
|
Monypenny, J;
Milewicz, H;
Flores-Borja, F;
Weitsman, G;
Cheung, A;
Chowdhury, R;
Burgoyne, T;
... Ng, T; + view all
(2018)
ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation.
Cell Reports
, 24
(3)
pp. 630-641.
10.1016/j.celrep.2018.06.066.
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Wong, LH;
Eden, ER;
Futter, CE;
(2018)
Roles for ER : endosome membrane contact sites in ligand-stimulated intraluminal vesicle formation.
[Review].
Biochemical Society Transactions
10.1042/BST20170432.
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2017
Agrawal, SA;
Burgoyne, T;
Eblimit, A;
Bellingham, J;
Parfitt, DA;
Lane, A;
Nichols, R;
... Cheetham, ME; + view all
(2017)
REEP6 Deficiency Leads to Retinal Degeneration through Disruption of ER Homeostasis and Protein Trafficking.
Human Molecular Genetics
, 26
(14)
pp. 2667-2677.
10.1093/hmg/ddx149.
|
Dragoni, S;
Hudson, N;
Kenny, B-A;
Burgoyne, T;
McKenzie, JA;
Gill, Y;
Blaber, R;
... Turowski, P; + view all
(2017)
Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions.
J Immunol
, 198
(10)
pp. 4074-4085.
10.4049/jimmunol.1600823.
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Kilpatrick, BS;
Eden, ER;
Hockey, LN;
Yates, E;
Futter, CE;
Patel, S;
(2017)
An Endosomal NAADP-Sensitive Two-Pore Ca(2+) Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling.
Cell Rep
, 18
(7)
pp. 1636-1645.
10.1016/j.celrep.2017.01.052.
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Melo, E;
Oertle, P;
Trepp, C;
Meistermann, H;
Burgoyne, T;
Sborgi, L;
Cabrera, AC;
... Iacone, R; + view all
(2017)
HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model.
EBioMedicine
10.1016/j.ebiom.2017.12.011.
|
Stefan, CJ;
Trimble, WS;
Grinstein, S;
Drin, G;
Reinisch, K;
De Camilli, P;
Cohen, S;
... McBride, HM; + view all
(2017)
Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers.
BMC Biology
, 15
(1)
, Article 102. 10.1186/s12915-017-0432-0.
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Tomas, A;
Jones, S;
Vaughan, SO;
Hochhauser, D;
Futter, CE;
(2017)
Stress-specific p38 MAP kinase activation is sufficient to drive EGF receptor endocytosis but not nuclear translocation.
Journal of Cell Science
, 130
(15)
pp. 2481-2490.
10.1242/jcs.202358.
|
Willén, K;
Edgar, JR;
Hasegawa, T;
Tanaka, N;
Futter, CE;
Gouras, GK;
(2017)
Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.
Molecular Neurodegeneration
, 12
, Article 61. 10.1186/s13024-017-0203-y.
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2016
Burgoyne, T;
Meschede, IP;
Futter, CE;
(2016)
New light on photoreceptor renewal.
Cell Cycle
, 15
(11)
pp. 1389-1390.
10.1080/15384101.2016.1164579.
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Eden, ER;
Sanchez-Heras, E;
Tsapara, A;
Sobota, A;
Levine, TP;
Futter, CE;
(2016)
Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport.
Developmental Cell
, 37
(5)
pp. 473-483.
10.1016/j.devcel.2016.05.005.
|
Futter, CE;
Cutler, DF;
(2016)
Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation.
Journal of Cell Biology
, 214
(3)
pp. 245-247.
10.1083/jcb.201607023.
|
Zhang, R;
Fruhwirth, GO;
Coban, O;
Barrett, JE;
Burgoyne, T;
Lee, SH;
Simonson, PD;
... Selvin, PR; + view all
(2016)
Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-Resolution Microscopy.
ACS Nano
, 11
(1)
pp. 249-257.
10.1021/acsnano.6b05356.
|
2015
Burgoyne, T;
O'Connor, MN;
Seabra, MC;
Cutler, DF;
Futter, CE;
(2015)
Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL.
J Cell Sci
, 128
(7)
1400 - 1407.
10.1242/jcs.164400.
|
Edgar, JR;
Willen, K;
Gouras, GK;
Futter, CE;
(2015)
ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-beta accumulation.
JOURNAL OF CELL SCIENCE
, 128
(14)
pp. 2520-2528.
10.1242/jcs.170233.
|
Futter, CE;
Tomas, A;
Vaughan, SO;
Burgoyne, T;
Sorkin, A;
Hochhauser, D;
(2015)
WASH and Tsg101/ALIX-dependent diversion of stress-internalised EGFR from the canonical endocytic pathway.
Nature Communications
, 6
, Article 7324. 10.1038/ncomms8324.
|
Georgiannakis, A;
Burgoyne, T;
Lueck, K;
Futter, C;
Greenwood, J;
Moss, SE;
(2015)
Retinal pigment epithelial cells mitigate the effects of complement attack by endocytosis of C5b-9.
Journal of Immunology
, 195
(7)
pp. 3382-3389.
10.4049/jimmunol.1500937.
|
Hidalgo-de-Quintana, J;
Schwarz, N;
Meschede, IP;
Stern-Schneider, G;
Powner, MB;
Morrison, EE;
Futter, CE;
... van der Spuy, J; + view all
(2015)
The Leber Congenital Amaurosis Protein AIPL1 and EB Proteins Co-Localize at the Photoreceptor Cilium.
PLoS One
, 10
(3)
, Article e0121440 . 10.1371/journal.pone.0121440.
|
Hockey, LN;
Kilpatrick, BS;
Eden, E;
Lin-Moshier, Y;
Brailoiu, GC;
Brailoiu, E;
Futter, CE;
... Patel, S; + view all
(2015)
Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by two-pore channel 2 inhibition.
Journal of Cell Science
, 128
pp. 232-238.
10.1242/jcs.164152.
|
Vaughan, SOK;
(2015)
The relationship between stress-induced endocytosis of epidermal growth factor receptor and cell survival.
Doctoral thesis , UCL (University College London).
|
Wavre-Shapton, ST;
Calvi, AA;
Turmaine, M;
Seabra, MC;
Cutler, DF;
Futter, CE;
Mitchison, HM;
(2015)
Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).
Human Molecular Genetics
, 24
(24)
pp. 7060-7074.
10.1093/hmg/ddv406.
|
2014
Edgar, JR;
Eden, ER;
Futter, CE;
(2014)
Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles.
Traffic
, 15
(2)
197- 211.
10.1111/tra.12139.
|
Hudson, N;
Powner, MB;
Sarker, MH;
Burgoyne, T;
Campbell, M;
Ockrim, ZK;
Martinelli, R;
... Turowski, P; + view all
(2014)
Differential apicobasal VEGF signaling at vascular blood-neural barriers.
Dev Cell
, 30
(5)
541 - 552.
10.1016/j.devcel.2014.06.027.
|
Wavre-Shapton, ST;
Meschede, IP;
Seabra, MC;
Futter, CE;
(2014)
Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium.
J Cell Sci
, 127
pp. 3852-3861.
10.1242/jcs.154757.
|
2013
Burgoyne, T;
Jolly, R;
Martin-Martin, B;
Seabra, MC;
Piccirillo, R;
Schiaffino, MV;
Futter, CE;
(2013)
Expression of OA1 limits the fusion of a subset of MVBs with lysosomes; a mechanism likely involved in the initial biogenesis of melanosomes.
Journal of Cell Science
, 126
(22)
10.1242/jcs.128561.
|
Wavre-Shapton, ST;
Tolmachova, T;
da Silva, ML;
Futter, CE;
Seabra, MC;
(2013)
Conditional ablation of the choroideremia gene causes age-related changes in mouse retinal pigment epithelium.
PLoS One
, 8
(2)
, Article 57769. 10.1371/journal.pone.0057769.
|
2010
Carvou, Nicolas;
Holic, Roman;
Li, Michelle;
Futter, Clare;
Skippen, Alison;
Cockcroft, Shamshad;
(2010)
Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPβ is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.
Journal of Cell Science
, 123
(8)
pp. 1262-1273.
10.1242/jcs.061986.
|
2006
Razi, M;
Futter, CE;
(2006)
Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation.
MOL BIOL CELL
, 17
(8)
3469 - 3483.
10.1091/mbc.E05-11-1054.
|
2004
Futter, CE;
Ramalho, JS;
Jaissle, GB;
Seeliger, MW;
Seabra, MC;
(2004)
The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells.
MOL BIOL CELL
, 15
(5)
2264 - 2275.
10.1091/mbc.E03-10-0772.
|
Tomas, A;
Futter, C;
Moss, SE;
(2004)
Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis.
JOURNAL OF CELL BIOLOGY
, 165
(6)
pp. 813-822.
10.1083/jcb.200311054.
|