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Number of items: 253.

Article

(2001) The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function Leeson CP,. Circulation , 102 (18) 1366-.

Alves, JD; Clapp, BR; Stidwill, R; Chen, PP; Hingorani, AD; Singer, M; Isenberg, DA; (2006) Human monoclonal IgG anticardiolipin antibodies induce nitric oxide synthase expression. ATHEROSCLEROSIS , 185 (2) 246 - 253. 10.1016/j.atherosclerosis.2005.06.044.

Angelakopoulou, A; Shah, T; Sofat, R; Shah, S; Berry, DJ; Cooper, J; Palmen, J; (2012) Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. European Heart Journal , 33 (3) 393 - 407. 10.1093/eurheartj/ehr225. Green open access
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Ariyaratnam, R; Casas, JP; Whittaker, J; Smeeth, L; Hingorani, AD; Sharma, P; (2007) Genetics of ischaemic stroke among persons of non-European descent: A meta-analysis of eight genes involving; 32,500 individuals. PLoS Medicine , 4 (4) , Article e131. 10.1371/journal.pmed.0040131. Green open access
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Arking, DE; Pulit, SL; Crotti, L; van der Harst, P; Munroe, PB; Koopmann, TT; Sotoodehnia, N; (2014) Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet , 46 (8) pp. 826-836. 10.1038/ng.3014.

Artigas, MS; Loth, DW; Wain, LV; Gharib, SA; Obeidat, M; Tang, WB; Zhai, GJ; (2011) Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. NAT GENET , 43 (11) 1082 - U70. 10.1038/ng.941.

Artigas, MS; Wain, LV; Repapi, E; Obeidat, M; Sayers, I; Burton, PR; Johnson, T; (2011) Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function. AM J RESP CRIT CARE , 184 (7) 786 - 795. 10.1164/rccm.201102-0192OC.

Asselbergs, FW; Guo, Y; van Iperen, EP; Sivapalaratnam, S; Tragante, V; Lanktree, MB; Lange, LA; (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet , 91 (5) pp. 823-838. 10.1016/j.ajhg.2012.08.032.

Bautista, LE; Smeeth, L; Hingorani, AD; Casas, JP; (2006) Estimation of bias in nongenetic observational studies using "Mendelian triangulation". ANN EPIDEMIOL , 16 (9) 675 - 680. 10.1016/j.annepidem.2006.02.001.

Bellamy, L; Casas, JP; Hingorani, AD; Williams, D; (2009) Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. LANCET , 373 (9677) 1773 - 1779.

Bellamy, L; Casas, JP; Hingorani, AD; Williams, DJ; (2007) Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BRIT MED J , 335 (7627) 974 - 977. 10.1136/bmj.39335.85301.BE.

Bellamy, L; Casas, JP; Hingorani, AD; Williams, DJ; (2007) Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ , 335 (7627) 974-. 10.1136/bmj.39335.385301.BE.

Berry, DJ; Vimaleswaran, KS; Whittaker, JC; Hingorani, AD; Hyppönen, E; (2012) Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D. PLoS One , 7 (5) , Article e37465. 10.1371/journal.pone.0037465. Green open access
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Bessant, R; Hingorani, A; Patel, L; MacGregor, A; Isenberg, DA; Rahman, A; (2004) Risk of coronary heart disease and stroke in a large British cohort of patients with systemic lupus erythematosus. RHEUMATOLOGY , 43 (7) 924 - 929. 10.1093/rheumatology/keh213.

Bhagat, K; Hingorani, A; Vallance, P; (1997) Flow associated or flow mediated dilatation? More than just semantics. Heart , 78 (1) pp. 7-8.

Bhagat, K; Hingorani, AD; Palacios, M; Charles, IG; Vallance, P; (1999) Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS. CARDIOVASC RES , 41 (3) 754 - 764.

Bodalia, PN; Grosso, AM; Sofat, R; Macallister, RJ; Smeeth, L; Dhillon, S; Casas, JP; (2013) Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials. Br J Clin Pharmacol , 76 (5) pp. 649-667. 10.1111/bcp.12083.

Brull, DJ; Serrano, N; Zito, F; Jones, L; Montgomery, HE; Rumley, A; Sharma, P; (2003) Human CRP gene polymorphism influences CRP levels - Implications for the prediction and pathogenesis of coronary heart disease. ARTERIOSCL THROM VAS , 23 (11) 2063 - 2069. 10.1161/01.ATV.0000084640.21712.9C.

Brunner, EJ; Kivimaki, M; Witte, DR; Lawlor, DA; Smith, GD; Cooper, JA; Miller, M; (2008) Inflammation, insulin resistance, and diabetes-mendelian randomization using CRP haplotypes points upstream. PLOS MED , 5 (8) , Article e155. 10.1371/journal.pmed.0050155. Green open access
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Casas, JP; Bautista, LE; Humphries, SE; Hingorani, AD; (2004) Endothelial nitric oxide synthase genotype and ischemic heart disease - Meta-analysis of 26 studies involving 23028 subjects. CIRCULATION , 109 (11) 1359 - 1365. 10.1161/01.CIR.0000121357.76910.A3.

Casas, JP; Bautista, LE; Smeeth, L; Sharma, P; Hingorani, AD; (2005) Homocysteine and stroke: evidence on a causal link from mendelian randomisation. LANCET , 365 (9455) 224 - 232.

Casas, JP; Cavalleri, GL; Bautista, LE; Smeeth, L; Humphries, SE; Hingorani, AD; (2006) Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: A HuGE review. AM J EPIDEMIOL , 164 (10) 921 - 935. 10.1093/aje/kwj302.

Casas, JP; Chua, WL; Loukogeorgakis, S; Vallance, P; Smeeth, L; Hingorani, AD; MacAllister, RJ; (2005) Effect of inhibitors of the renin-angiotensin system and other anti hypertensive drugs on renal outcomes: systematic review and meta-analysis. LANCET , 366 (9502) 2026 - 2033.

Casas, JP; Cooper, J; Miller, GJ; Hingorani, AD; Humphries, SE; (2006) Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies. ANN HUM GENET , 70 145 - 169. 10.1111/j.1469-1809.2005.00241.x.

Casas, JP; Hingorani, AD; (2012) The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet , 379 (9822) 1214 - 1224. 10.1016/S0140-6736(12)60110-X. Green open access
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Casas, JP; Hingorani, AD; Bautista, LE; Sharma, P; (2004) Meta-analysis of genetic studies in ischemic stroke - Thirty-two genes involving approximately 18 000 cases and 58 000 controls. ARCH NEUROL-CHICAGO , 61 (11) 1652 - 1661.

Casas, JP; Hingorani, AD; Humphries, SE; Smeeth, L; Bautista, LE; (2004) Do meta-analyses of association studies of endothelial nitric oxide synthase variants and ischemic heart disease provide conclusive answers? Response. CIRCULATION , 110 (11) E305 - E306.

Casas, JP; Hingorani, AD; MacAllister, RJ; Smeeth, L; (2006) Progression of renal disease - can we forget about inhibition of the renin-angiotensin system? Authors' reply. NEPHROL DIAL TRANSPL , 21 (9) 2352 - 2353. 10.1093/ndt/gfl316.

Casas, JP; Ninio, E; Panayiotou, A; Palmen, J; Cooper, JA; Ricketts, SL; Sofat, R; (2010) PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A2 Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry (vol 121, pg 2284, 2010). CIRCULATION , 122 (3) E400 - E400. 10.1161/CIR.0b013e3181eb187c.

Casas, JP; Ninio, E; Panayiotou, A; Palmen, J; Cooper, JA; Ricketts, SL; Sofat, R; (2010) PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A(2) Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry. CIRCULATION , 121 (21) 2284 - U74. 10.1161/CIRCULATIONAHA.109.923383.

Casas, JP; Shah, T; Cooper, J; Hawe, E; McMahon, AD; Gaffney, D; Packard, CJ; (2006) Insight into the nature of the CRP-coronary event association using Mendelian randomization. INT J EPIDEMIOL , 35 (4) 922 - 931. 10.1093/ije/dyl041.

Casas, JP; Shah, T; Hingorani, AD; Danesh, J; Pepys, MB; (2008) C-reactive protein and coronary heart disease: a critical review. J INTERN MED , 264 (4) 295 - 314. 10.1111/j.1365-2796.2008.02015.x.

Casas, JP; Vallance, P; Smeeth, L; Hingorani, AD; MacAllister, RJ; (2006) Renoprotective effects of renin-angiotensin-system inhibitors - Reply. LANCET , 367 (9514) 900 - 902.

Chakravarthy, U; McKay, GJ; de Jong, PT; Rahu, M; Seland, J; Soubrane, G; Tomazzoli, L; (2013) ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study. Ophthalmology , 120 (2) pp. 342-348. 10.1016/j.ophtha.2012.08.004.

Chan, NN; MacAllister, RJ; Colhoun, HM; Vallance, P; Hingorani, AD; (2001) Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. J CLIN ENDOCR METAB , 86 (6) 2499 - 2504.

Chan, NN; Vallance, P; Colhoun, HM; MacAllister, RJ; Hingorani, AD; Conway, GS; (2002) The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome. CLIN ENDOCRINOL , 56 (5) 615 - 620.

Chan, NN; Vallance, PJ; Macallister, RJ; Hingorani, AD; Colhoun, HM; (2000) Impaired nitric oxide response in resistance vessels in human type 1 diabetes in vivo. CIRCULATION , 102 (18) 326 - 326.

Chen, Z; Ahluwalia, A; Selwood, DL; Vallance, P; Hingorani, AD; (1999) Enhancement of endothelium-dependent vasodilatation by oestradiol 17-beta: Role of the pterin pathway. BRIT J PHARMACOL , 126 U32 - U32.

Clapp, BR; Hingorani, AD; Kharbanda, RK; Mohamed-Ali, V; Stephens, JW; Vallance, P; MacAllister, RJ; (2004) Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. CARDIOVASC RES , 64 (1) 172 - 178. 10.1016/j.cardiores.2004.06.020.

Clapp, BR; Hirschfield, GM; Storry, C; Gallimore, JR; Stidwill, RP; Singer, M; Deanfield, JE; (2005) Inflammation and endothelial function - Direct vascular effects of human C-reactive protein on nitric oxide bioavailability. CIRCULATION , 111 (12) 1530 - 1536. 10.1161/01.CIR.0000159336.31613.31.

Clarke, R; Emberson, JR; Breeze, E; Casas, JP; Parish, S; Hingorani, AD; Fletcher, A; (2008) Biomarkers of inflammation predict both vascular and non-vascular mortality in older men. EUR HEART J , 29 (6) 800 - 809. 10.1093/eurheartj/ehn049.

Costelloe, SJ; El-Sayed Moustafa, JS; Drenos, F; Palmen, J; Li, Q; Whiting, S; Thomas, M; (2012) Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits. Circ Cardiovasc Genet , 5 (5) pp. 555-560. 10.1161/CIRCGENETICS.111.961037.

D'Aiuto, F; Casas, JP; Shah, T; Humphries, SE; Hingorani, AD; Tonetti, MS; (2005) C-reactive protein (+1444C > T) polymorphism influences CRP response following a moderate inflammatory stimulus. ATHEROSCLEROSIS , 179 (2) 413 - 417. 10.1016/j.atherosclerosis.2004.10.036.

D'Aiuto, F; Sabbah, W; Netuveli, G; Donos, N; Hingorani, AD; Deanfield, J; Tsakos, G; (2008) Association of the metabolic syndrome with severe periodontitis in a large US population-based survey. J CLIN ENDOCR METAB , 93 (10) 3989 - 3994. 10.1210/jc.2007-2522.

Dastani, Z; Hivert, MF; Timpson, N; Perry, JR; Yuan, X; Scott, RA; Henneman, P; (2012) Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genetics , 8 (3) , Article e1002607. 10.1371/journal.pgen.1002607. Green open access
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Denaxas, SC; George, J; Herrett, E; Shah, AD; Kalra, D; Hingorani, AD; Kivimaki, M; (2012) Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER). Int J Epidemiol , 41 (6) pp. 1625-1638. 10.1093/ije/dys188. Gold open access

Dickerson, JEC; Hingorani, AD; Ashby, MJ; Palmer, CR; Brown, MJ; (1999) Optimisation of antihypertensive treatment by crossover rotation of four major classes. LANCET , 353 (9169) 2008 - 2013.

Donald, AE; Charakida, M; Falaschetti, E; Lawlor, DA; Halcox, JP; Golding, J; Hingorani, AD; (2010) Determinants of vascular phenotype in a large childhood population: the Avon Longitudinal Study of Parents and Children (ALSPAC). EUR HEART J , 31 (12) 1502 - 1510. 10.1093/eurheartj/ehq062.

Douglas, IJ; Evans, SJ; Hingorani, AD; Grosso, AM; Timmis, A; Hemingway, H; Smeeth, L; (2012) Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs. BMJ , 345 , Article e4388.

Drenos, F; Talmud, PJ; Casas, JP; Smeeth, L; Palmen, J; Humphries, SE; Hingorani, AD; (2009) Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. HUM MOL GENET , 18 (12) 2305 - 2316. 10.1093/hmg/ddp159.

Dupuis, J; Langenberg, C; Prokopenko, I; Saxena, R; Soranzo, N; Jackson, AU; Wheeler, E; (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. NAT GENET , 42 (2) 105 - U32. 10.1038/ng.520.

Dupuis, J; Langenberg, C; Prokopenko, I; Saxena, R; Soranzo, N; Jackson, AU; Wheeler, E; (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010). NAT GENET , 42 (5) 464 - 464. 10.1038/ng0510-464a.

D’Aiuto, F.; Casas, J.P.; Shah, T.; Humphries, S.E.; Hingorani, A.D.; Tonetti, M.S.; (2005) C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus. Atherosclerosis , 179 (2) pp. 413-417. 10.1016/j.atherosclerosis.2004.10.036.

Ehret, GB; Munroe, PB; Rice, KM; Bochud, M; Johnson, AD; Chasman, DI; Smith, AV; (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. NATURE , 478 (7367) 103 - 109. 10.1038/nature10405.

Falaschetti, E; Hingorani, AD; Jones, A; Charakida, M; Finer, N; Whincup, P; Lawlor, DA; (2010) Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children. EUR HEART J , 31 (24) 3063 - 3072. 10.1093/eurheartj/ehq355.

Fox, ER; Young, JH; Li, Y; Dreisbach, AW; Keating, BJ; Musani, SK; Liu, K; (2011) Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet , 20 (11) pp. 2273-2284. 10.1093/hmg/ddr092.

Freathy, RM; Kazeem, GR; Morris, RW; Johnson, PC; Paternoster, L; Ebrahim, S; Hattersley, AT; (2011) Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. International Journal of Epidemiology , 40 (6) pp. 1617-1628. 10.1093/ije/dyr077. Green open access
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Gaunt, TR; Shah, S; Nelson, CP; Drenos, F; Braund, PS; Adeniran, I; Folkersen, L; (2012) Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip. Circ Cardiovasc Genet , 5 (6) pp. 630-638. 10.1161/CIRCGENETICS.112.962852.

Gaunt, TR; Zabaneh, D; Shah, S; Guyatt, A; Ladroue, C; Kumari, M; Drenos, F; (2013) Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip. Thromb Haemost , 110 (5) pp. 995-1003. 10.1160/TH13-02-0087.

Gertow, K; Sennblad, B; Strawbridge, RJ; Ohrvik, J; Zabaneh, D; Shah, S; Veglia, F; (2012) Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. Circ Cardiovasc Genet , 5 (6) pp. 656-665. 10.1161/CIRCGENETICS.112.963660.

Giambartolomei, C; Vukcevic, D; Schadt, EE; Franke, L; Hingorani, AD; Wallace, C; Plagnol, V; (2014) Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics. PLoS Genet , 10 (5) , Article e1004383. 10.1371/journal.pgen.1004383. Green open access
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Grosso, A; Douglas, I; Hingorani, A; MacAllister, R; Smeeth, L; (2008) Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions. BRIT J CLIN PHARMACO , 66 (5) 689 - 694. 10.1111/j.1365-2125.2008.03273.x. Gold open access

Grosso, A; Douglas, I; Hingorani, AD; MacAllister, R; Hubbard, R; Smeeth, L; (2009) Inhaled tiotropium bromide and risk of stroke. BRIT J CLIN PHARMACO , 68 (5) 731 - 736. 10.1111/j.1365-2125.2009.03517.x.

Grosso, A; Douglas, I; MacAllister, R; Petersen, I; Smeeth, L; Hingorani, AD; (2011) Use of the self-controlled case series method in drug safety assessment. EXPERT OPIN DRUG SAF , 10 (3) 337 - 340. 10.1517/14740338.2011.562187.

Grosso, AM; Bodalia, PN; MacAllister, RJ; Hingorani, AD; Moon, JC; Scott, MA; (2011) Cost-saving opportunities and angiotensin-II receptor blocker prescribing. INT J CLIN PRACT , 65 (8) 912 - 912. 10.1111/j.1742-1241.2011.02730.x.

Grosso, AM; Bodalia, PN; MacAllister, RJ; Hingorani, AD; Moon, JC; Scott, MA; (2011) Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis. INT J CLIN PRACT , 65 (3) 253 - 263. 10.1111/j.1742-1241.2011.02633.x.

HINGORANI, AD; (1993) THE FLOSEQUINAN EXPERIENCE AND ITS IMPLICATIONS. BRIT J HOSP MED , 50 (11) 683 - 683.

HINGORANI, AD; BLOOMBERG, TJ; (1995) ULTRASOUND-GUIDED PIGTAIL CATHETER DRAINAGE OF MALIGNANT PERICARDIAL-EFFUSIONS. CLIN RADIOL , 50 (1) 15 - 19.

HINGORANI, AD; BROWN, MJ; (1995) A SIMPLE MOLECULAR ASSAY FOR THE C-1166 VARIANT OF THE ANGIOTENSIN-II TYPE-1 RECEPTOR GENE. BIOCHEM BIOPH RES CO , 213 (2) 725 - 729.

HINGORANI, AD; DOLLERY, CT; OAKLEY, CM; BLOOM, SR; COHEN, J; (1992) HAMMERSMITH STAFF ROUNDS - POSTINFECTIOUS MYOCARDITIS. BRIT MED J , 304 (6843) 1676 - 1678.

HINGORANI, AD; FOLEY, TH; (1995) NONSUSTAINED BROAD-COMPLEX TACHYCARDIA FOLLOWING INTRAVENOUS ADENOSINE. J ACCID EMERG MED , 12 (3) 208 - 209.

HINGORANI, AD; JONES, AT; DZIERSK, J; GOLDINGWOOD, D; LEIGH, JM; (1994) ADULT EPIGLOTTITIS - ESTABLISH AN AIRWAY EARLY. BRIT MED J , 308 (6930) 719 - 719.

HINGORANI, AD; MACDOUGALL, IC; BROWNE, M; WALKER, RWH; TOMSON, CRV; (1993) SUCCESSFUL TREATMENT OF ACUTE D-LACTATE ENCEPHALOPATHY BY HEMODIALYSIS. NEPHROL DIAL TRANSPL , 8 (11) 1283 - 1285.

HINGORANI, AD; WAINSWORTH, RW; (1993) PULMONARY MICROEMBOLIZATION AND TEMAZEPAM. BRIT MED J , 307 (6904) 623 - 624.

Harrison, SC; Smith, AJ; Jones, GT; Swerdlow, DI; Rampuri, R; Bown, MJ; Aneurysm Consortium, ; (2013) Interleukin-6 receptor pathways in abdominal aortic aneurysm. European Heart Journal , 34 (48) , Article ehs354v1. 10.1093/eurheartj/ehs354. Green open access
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Harrison, SC; Zabaneh, D; Asselbergs, FW; Drenos, F; Jones, GT; Shah, S; Gertow, K; (2013) A gene-centric study of common carotid artery remodelling. Atherosclerosis , 226 (2) pp. 440-446. 10.1016/j.atherosclerosis.2012.11.002.

Healy, DG; Abou-Sleiman, PM; Lees, AJ; Casas, JP; Quinn, N; Bhatia, K; Hingorani, AD; (2004) Tau gene and Parkinson's disease: a case-control study and meta-analysis. J NEUROL NEUROSUR PS , 75 (7) 962 - 965. 10.1136/jnnp.2003.026203.

Hemingway, H; Philipson, P; Chen, RL; Fitzpatrick, NK; Damant, J; Shipley, M; Abrams, KR; (2010) Evaluating the Quality of Research into a Single Prognostic Biomarker: A Systematic Review and Meta-analysis of 83 Studies of C-Reactive Protein in Stable Coronary Artery Disease. PLOS Medicine , 7 (6) , Article e1000286. 10.1371/journal.pmed.1000286. Green open access
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Henriksson, M; Palmer, S; Chen, RL; Damant, J; Fitzpatrick, NK; Abrams, K; Hingorani, AD; (2010) Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery. BRIT MED J , 340 , Article b5606. 10.1136/bmj.b5606.

Herder, C; Nuotio, ML; Shah, S; Blankenberg, S; Brunner, EJ; Carstensen, M; Gieger, C; (2014) Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes , 63 (12) pp. 4343-4359. 10.2337/db14-0731.

Hingorani, A; (2004) Resolving inconsistency in the results of genetic association studies of cardiovascular disease. Clinical Science , 107 (3) pp. 251-253.

Hingorani, AD; (2004) Diet, the endothelium and atherosclerosis. CLIN SCI , 106 (5) 447 - 448. 10.1042/CS20040023.

Hingorani, AD; (2003) Endothelial nitric oxide synthase polymorphisms and hypertension. CURR HYPERTENS REP , 5 (1) 19 - 25.

Hingorani, AD; (2001) Polymorphisms in endothelial nitric oxide synthase and atherogenesis - John French Lecture 2000. ATHEROSCLEROSIS , 154 (3) 521 - 527.

Hingorani, AD; (1992) Postinfectious myocarditis. BMJ , 304 (6843) pp. 1676-1678.

Hingorani, AD; Bhagat, K; Palacios, M; Griffin, GE; MacAllister, RJ; Vallance, P; (1999) Acute systemic inflammation impairs endothelium-dependent dilatation in humans. BRIT J PHARMACOL , 126 U31 - U31.

Hingorani, AD; Brown, MJ; (1996) Identifying the genes for human hypertension. NEPHROL DIAL TRANSPL , 11 (4) 575 - 586.

Hingorani, AD; Brown, MJ; (1996) A simple molecular assay for the C-1166 variant of the angiotensin II type 1 receptor gene (vol 213, pg 725, 1995). BIOCHEM BIOPH RES CO , 218 (1) 420 - 420.

Hingorani, AD; Chan, NN; (2001) D-lactate encephalopathy. LANCET , 358 (9295) 1814 - 1814.

Hingorani, AD; Cross, J; Kharbanda, RK; Mullen, MJ; Bhagat, K; Taylor, M; Donald, AE; (2000) Acute systemic inflammation impairs endothelium-dependent dilatation in humans. CIRCULATION , 102 (9) 994 - 999.

Hingorani, AD; Cross, JM; Kharbanda, RK; Mullen, MJ; Bhagat, K; Taylor, M; Donald, AE; (1999) Acute systemic inflammation impairs endothelium-dependent dilation in humans. CIRCULATION , 100 (18) 48 - 48.

Hingorani, AD; D'Aiuto, F; (2008) Chronic inflammation, periodontitis and cardiovascular diseases. ORAL DIS , 14 (2) 102 - 104. 10.1111/j.1601-0825.2007.01439.x.

Hingorani, AD; Hemingway, H; (2011) How should we balance individual and population benefits of statins for preventing cardiovascular disease? BRIT MED J , 342 , Article c6244. 10.1136/bmj.c6244.

Hingorani, AD; Jia, HY; Stevens, PA; Hopper, R; Dickerson, JEC; Brown, MJ; (1995) Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition. JOURNAL OF HYPERTENSION , 13 (12) 1602 - 1609.

Hingorani, AD; Liang, CF; Fatibene, J; Lyon, A; Monteith, S; Parsons, A; Haydock, S; (1999) A common variant of the endothelial nitric oxide synthase (Glu(298)-> Asp) is a major risk factor for coronary artery disease in the UK. CIRCULATION , 100 (14) 1515 - 1520.

Hingorani, AD; Liang, CF; Fatibene, J; Parsons, A; Hopper, RV; Trutwein, D; Stephens, NG; (1997) A common variant of the endothelial nitric oxide synthase gene is a risk factor for coronary atherosclerosis in the east Anglian region of the UK. CIRCULATION , 96 (8) 3050 - 3050.

Hingorani, AD; OHanlon, S; Halloran, SP; Wright, JP; Foley, TH; (1997) Evaluation of a paired creatine kinase test for the diagnosis of acute myocardial infarction in patients with a non-diagnostic electrocardiogram. J ACCID EMERG MED , 14 (3) 134 - 138.

Hingorani, AD; Psaty, BM; (2010) Modeling Cardiovascular Disease Prevention Reply. JAMA-J AM MED ASSOC , 303 (9) 835 - 835.

Hingorani, AD; Psaty, BM; (2009) Primary Prevention of Cardiovascular Disease Time to Get More or Less Personal? JAMA-J AM MED ASSOC , 302 (19) 2144 - 2145.

Hingorani, AD; Shah, T; Casas, JP; (2006) Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk. EUR HEART J , 27 (11) 1261 - 1263. 10.1193/eurheart/ehl852.

Hingorani, AD; Shah, T; Casas, JP; (2006) Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk. Eur Heart J , 27 (11) pp. 1261-1263. 10.1093/eurheartj/ehi852.

Hingorani, AD; Shah, T; Casas, JP; Humphries, SE; Talmud, PJ; (2009) C-Reactive Protein and Coronary Heart Disease: Predictive Test or Therapeutic Target? CLIN CHEM , 55 (2) 239 - 255. 10.1373/clinchem.2008.115923.

Hingorani, AD; Shah, T; Kumari, M; Sofat, R; Smeeth, L; (2010) Science, medicine, and the future Translating genomics into improved healthcare. BRIT MED J , 341 , Article c5945. 10.1136/bmj.c5945.

Hingorani, AD; Shah, T; Kumari, M; Sofat, R; Smeeth, L; (2010) Translating genomics into improved healthcare. BMJ , 341 c5945-.

Hingorani, AD; Sharma, P; Jia, HY; Hopper, R; Brown, MJ; (1996) Blood pressure and the M235T polymorphism of the angiotensinogen gene. HYPERTENSION , 28 (5) 907 - 911.

Hingorani, AD; Sofat, R; Morris, RW; Whincup, P; Lowe, GD; Mindell, J; Sattar, N; (2012) Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease? Eur Heart J , 33 (18) pp. 2258-2264. 10.1093/eurheartj/ehs168.

Hingorani, AD; Vallance, P; (1999) Hypothesis of program is flawed - Reply. BRIT MED J , 318 (7195) 1419 - 1419.

Hingorani, AD; Vallance, P; (1999) A simple computer program for guiding management of cardiovascular risk factors and prescribing. BRIT MED J , 318 (7176) 101 - 105.

Hingorani, AD; Windt, DA; Riley, RD; Abrams, K; Moons, KG; Steyerberg, EW; Schroter, S; (2013) Prognosis research strategy (PROGRESS) 4: stratified medicine research. BMJ , 346 , Article e5793. Gold open access

Holmes, MV; Asselbergs, FW; Palmer, TM; Drenos, F; Lanktree, MB; Nelson, CP; Dale, CE; (2015) Mendelian randomization of blood lipids for coronary heart disease. Eur Heart J , 36 (9) 539 - 550. 10.1093/eurheartj/eht571. Green open access
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Holmes, MV; Casas, JP; Hingorani, AD; (2011) Putting genomics into practice. BRIT MED J , 343 , Article d4953. 10.1136/bmj.d4953.

Holmes, MV; Dale, CE; Zuccolo, L; Silverwood, RJ; Guo, Y; Ye, Z; Prieto-Merino, D; (2014) Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ , 349 , Article g4164. 10.1136/bmj.g4164. Green open access
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Holmes, MV; Exeter, HJ; Folkersen, L; Nelson, CP; Guardiola, M; Cooper, JA; Sofat, R; (2014) Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels. Circ Cardiovasc Genet , 7 (2) pp. 144-150. 10.1161/CIRCGENETICS.113.000271.

Holmes, MV; Harrison, S; Talmud, PJ; Hingorani, AD; Humphries, SE; (2011) Utility of genetic determinants of lipids and cardiovascular events in assessing risk. NAT REV CARDIOL , 8 (4) 207 - 221. 10.1038/nrcardio.2011.6.

Holmes, MV; Hingorani, AD; Casas, JP; (2012) CYP2C19 Genotype and Cardiovascular Events Reply. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION , 307 (14) pp. 1484-1485. 10.1001/jama.2012.446.

Holmes, MV; Lange, LA; Palmer, T; Lanktree, MB; North, KE; Almoguera, B; Buxbaum, S; (2014) Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. Am J Hum Genet , 94 (2) pp. 198-208. 10.1016/j.ajhg.2013.12.014.

Holmes, MV; Newcombe, P; Hubacek, JA; Sofat, R; Ricketts, SL; Cooper, J; Breteler, MMB; (2011) Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. LANCET , 378 (9791) 584 - 594. 10.1016/S0140-6736(11)60872-6. Gold open access

Holmes, MV; Perel, P; Shah, T; Hingorani, AD; Casas, JP; (2011) CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis. JAMA , 306 (24) pp. 2704-2714. 10.1001/jama.2011.1880.

Holmes, MV; Shah, T; Vickery, C; Smeeth, L; Hingorani, AD; Casas, JP; (2009) Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies. PLOS ONE , 4 (12) , Article e7960. 10.1371/journal.pone.0007960. Green open access
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Holmes, MV; Simon, T; Exeter, HJ; Folkersen, L; Asselbergs, FW; Guardiola, M; Cooper, JA; (2013) Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol , 62 (21) pp. 1966-1976. 10.1016/j.jacc.2013.06.044.

Holmes, MV; Simon, T; Exeter, HJ; Hingorani, AD; Sabatine, MS; Mallat, Z; Casas, JP; (2014) Reply: limits of Mendelian randomization analyses in selection of secretory phospholipase A2-IIA as a valid therapeutic target for prevention of cardiovascular disease. J Am Coll Cardiol , 63 (9) 943-. 10.1016/j.jacc.2013.10.070.

Howe, LD; Galobardes, B; Sattar, N; Hingorani, AD; Deanfield, J; Ness, AR; Davey-Smith, G; (2010) Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study. INT J OBESITY , 34 (7) 1149 - 1159. 10.1038/ijo.2010.52.

Hu, Y; Li, L; Ehm, MG; Bing, N; Song, K; Nelson, MR; Talmud, PJ; (2013) The benefits of using genetic information to design prevention trials. Am J Hum Genet , 92 (4) pp. 547-557. 10.1016/j.ajhg.2013.03.003.

Humphries, SE; Hingorani, A; (2006) Pharmacogenetics: Progress, pitfalls and clinical potential for coronary heart disease. VASC PHARMACOL , 44 (2) 119 - 125. 10.1016/j.vph.2005.10.003.

International Consortium for Blood Pressure Genome-Wide Associat, ; Ehret, GB; Munroe, PB; Rice, KM; Bochud, M; Johnson, AD; Chasman, DI; (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature , 478 (7367) pp. 103-109. 10.1038/nature10405.

Jeerooburkhan, N; Jones, LC; Bujac, S; Cooper, JA; Miller, GJ; Vallance, P; Humphries, SE; (2001) Genetic and environmental determinants of plasma nitrogen oxides and risk of ischemic heart disease. HYPERTENSION , 38 (5) 1054 - 1061.

Jensen, AC; Barker, A; Kumari, M; Brunner, EJ; Kivimaki, M; Hingorani, AD; Wareham, NJ; (2011) Associations of Common Genetic Variants With Age-Related Changes in Fasting and Postload Glucose Evidence From 18 Years of Follow-Up of the Whitehall II Cohort. DIABETES , 60 (5) 1617 - 1623. 10.2337/db10-1393.

Jia, HY; Hingorani, AD; Sharma, P; Hopper, R; Dickerson, C; Trutwein, D; Lloyd, DD; (1999) Association of the G(s)alpha gene with essential hypertension and response to beta-blockade. HYPERTENSION , 34 (1) 8 - 14.

Johnson, T; Gaunt, TR; Newhouse, SJ; Padmanabhan, S; Tomaszewski, M; Kumari, M; Morris, RW; (2011) Blood pressure loci identified with a gene-centric array. Am J Hum Genet , 89 (6) pp. 688-700. 10.1016/j.ajhg.2011.10.013.

Jones, A; Charakida, M; Falaschetti, E; Hingorani, AD; Finer, N; Masi, S; Donald, AE; (2012) Adipose and height growth through childhood and blood pressure status in a large prospective cohort study. Hypertension , 59 (5) pp. 919-925. 10.1161/HYPERTENSIONAHA.111.187716. Gold open access

Jones, LC; Hingorani, AD; (2005) Genetic regulation of endothelial function. HEART , 91 (10) 1275 - 1277. 10.1136/hrt.2005.061325.

Jones, LC; Tran, CTL; Leiper, JM; Hingorani, AD; Vallance, P; (2003) Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells. BIOCHEM BIOPH RES CO , 310 (3) 836 - 843. 10.1016/j.bbrc.2003.09.097.

Ken-Dror, G; Drenos, F; Humphries, SE; Talmud, PJ; Hingorani, AD; Kivimaki, M; Kumari, M; (2010) Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men. J THROMB HAEMOST , 8 (11) 2394 - 2403. 10.1111/j.1538-7836.2010.04035.x.

Khan, TA; Shah, T; Prieto, D; Zhang, W; Price, J; Fowkes, GR; Cooper, J; (2013) Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. Int J Epidemiol , 42 (2) pp. 475-492. 10.1093/ije/dyt034.

Kharbanda, RK; Walton, B; Allen, M; Klein, N; Hingorani, AD; MacAllister, RJ; Vallance, P; (2002) Prevention of inflammation-induced endothelial dysfunction - A novel vasculo-protective action of aspirin. CIRCULATION , 105 (22) 2600 - 2604. 10.1161/01.CIR.0000017863.52347.6C.

Kivimaki, M; Lawlor, DA; Smith, GD; Kumari, M; Donald, A; Britton, A; Casas, JP; (2008) Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study. PLOS ONE , 3 (8) , Article e3013. 10.1371/journal.pone.0003013. Green open access
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Kumari, M; Holmes, MV; Dale, CE; Hubacek, J; Palmer, TM; Pikhart, H; Peasey, A; (2014) Alcohol Consumption and Cognitive Performance: a Mendelian Randomisation Study. Addiction , 109 (9) 1462- 1471. 10.1111/add.12568. Green open access
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Kuper, H; Nicholson, A; Kivimaki, M; Aitsi-Selmi, A; Cavalleri, G; Deanfield, JE; Heuschmann, P; (2009) Evaluating the causal relevance of diverse risk markers: horizontal systematic review. BRIT MED J , 339 , Article b4265. 10.1136/bmj.b4265.

Lanktree, MB; Guo, YR; Murtaza, M; Glessner, JT; Bailey, SD; Onland-Moret, NC; Lettre, G; (2011) Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. AM J HUM GENET , 88 (1) 6 - 18. 10.1016/j.ajhg.2010.11.007.

Leeson, CP; Hingorani, AD; Mullen, MJ; Jeerooburkhan, N; Kattenhorn, M; Muller, DP; Lucas, A; (2000) The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. CIRCULATION , 102 (18) 279 - 279.

Leeson, CPM; Hingorani, AD; Mullen, MJ; Jeerooburkhan, N; Kattenhorn, M; Cole, TJ; Muller, DPR; (2002) Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. CIRC RES , 90 (11) 1153 - 1158. 10.1161/01.RES.0000020562.07492.D4.

Leusink, M; Maitland-van der Zee, AH; Ding, B; Drenos, F; van Iperen, EP; Warren, HR; Caulfield, MJ; (2016) A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering. Pharmacogenomics , 17 (6) pp. 583-591. 10.2217/pgs.16.8.

Locke, AE; Kahali, B; Berndt, SI; Justice, AE; Pers, TH; Day, FR; Powell, C; (2015) Genetic studies of body mass index yield new insights for obesity biology. Nature , 518 (7538) pp. 197-206. 10.1038/nature14177.

Lum, DW; Perel, P; Hingorani, AD; Holmes, MV; (2013) CYP2D6 Genotype and Tamoxifen Response for Breast Cancer: A Systematic Review and Meta-Analysis. PLoS One , 8 (10) , Article e76648. 10.1371/journal.pone.0076648. Green open access
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MacAllister, R; Hingorani, AD; Casas, JP; (2004) Ximelagatran or warfarin in atrial fibrillation? LANCET , 363 (9410) 735 - 736.

Mayahi, L; Heales, S; Owen, D; Casas, JP; Harris, J; MacAllister, RJ; Hingorani, AD; (2007) (6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm. ARTERIOSCL THROM VAS , 27 (6) 1334 - 1339. 10.1161/ATVBAHA.107.142257.

Mayahi, L; Mason, L; Bleasdale-Barr, K; Donald, A; Trender-Gerhard, I; Sweeney, MG; Davis, MB; (2010) Endothelial, Sympathetic, and Cardiac Function in Inherited (6R)-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin Deficiency. CIRC-CARDIOVASC GENE , 3 (6) 513 - 522. 10.1161/CIRCGENETICS.110.957605.

Mayahi, L; Mason, L; Storry, C; Donald, A; Trender-Gherhard, I; Mathias, C; Deanfield, J; (2006) Endothelial, sympathetic and cardiac function in inherited 6R-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin deficiency. CIRCULATION , 114 (18) 283 - 283.

McKay, GJ; Patterson, CC; Chakravarthy, U; Dasari, S; Klaver, CC; Vingerling, JR; Ho, L; (2011) Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat , 32 (12) pp. 1407-1416. 10.1002/humu.21577.

McKay, GJ; Silvestri, G; Chakravarthy, U; Dasari, S; Fritsche, LG; Weber, BH; Keilhauer, CN; (2011) Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People. AM J EPIDEMIOL , 173 (12) 1357 - 1364. 10.1093/aje/kwr015.

Minassian, C; D'Aiuto, F; Hingorani, AD; (2011) Invasive Dental Treatment and Risk for Vascular Events RESPONSE. ANN INTERN MED , 154 (6) 442 - 442. 10.1059/0003-4819-154-6-201103150-00016.

Minassian, C; D'Aiuto, F; Hingorani, AD; Smeeth, L; (2010) Invasive Dental Treatment and Risk for Vascular Events A Self-Controlled Case Series. ANN INTERN MED , 153 (8) 499 - W181.

Munafò, MR; Timofeeva, MN; Morris, RW; Prieto-Merino, D; Sattar, N; Brennan, P; Johnstone, EC; (2012) Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure. Journal of the National Cancer Institute , 104 (10) 740 - 748. 10.1093/jnci/djs191. Green open access
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Newcombe, PJ; Verzilli, C; Casas, JP; Hingorani, AD; Smeeth, L; Whittaker, JC; (2009) Multilocus Bayesian Meta-Analysis of Gene-Disease Associations. AM J HUM GENET , 84 (5) 567 - 580. 10.1016/j.ajhg.2009.04.001.

Noori, M; Donald, AE; Angelakopoulou, A; Hingorani, AD; Williams, DJ; (2010) Prospective Study of Placental Angiogenic Factors and Maternal Vascular Function Before and After Preeclampsia and Gestational Hypertension. CIRCULATION , 122 (5) 478 - 487. 10.1161/CIRCULATIONAHA.109.895458.

Noori, M; Donald, AE; Hingorani, AD; Williams, DJ; (2012) Gestational Vasoconstriction of the Brachial Artery at Low-Flow; a Novel Observation That Suggests Shear Stress Has a Primary Role in the Vasodilatation of Healthy Pregnancy. REPRODUCTIVE SCIENCES , 19 (S3) 217A-217A.

O'Neill, SG; Pego-Reigosa, JM; Hingorani, AD; Bessant, R; Isenberg, DA; Rahman, A; (2009) Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus. RHEUMATOLOGY , 48 (5) 573 - 575. 10.1093/rheumatology/kep037.

Palmer, ND; McDonough, CW; Hicks, PJ; Roh, BH; Wing, MR; An, SS; Hester, JM; (2012) A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One , 7 (1) , Article e29202. 10.1371/journal.pone.0029202. Green open access
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Papp, AC; Pinsonneault, JK; Wang, D; Newman, LC; Gong, Y; Johnson, JA; Pepine, CJ; (2012) Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. PLoS One , 7 (3) , Article e31930. 10.1371/journal.pone.0031930. Green open access
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Patel, RS; Asselbergs, FW; Quyyumi, AA; Palmer, TM; Finan, CI; Tragante, V; Deanfield, J; (2014) Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis. Journal of the American College of Cardiology , 63 (21) pp. 2234-2245. 10.1016/j.jacc.2014.01.065. Green open access
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Rapsomaniki, E; Shah, A; Perel, P; Denaxas, S; George, J; Nicholas, O; Udumyan, R; (2014) Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients. Eur Heart J , 35 (13) pp. 844-852. 10.1093/eurheartj/eht533. Green open access
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Repapi, E; Sayers, I; Wain, LV; Burton, PR; Johnson, T; Obeidat, M; Zhao, JH; (2010) Genome-wide association study identifies five loci associated with lung function. NAT GENET , 42 (1) 36 - U51. 10.1038/ng.501.

Sarwar, N; Sandhu, MS; Ricketts, SL; Butterworth, AS; Di Angelantonio, E; Boelcholdt, SM; Ouwehand, W; (2010) Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. LANCET , 375 (9726) 1634 - 1639.

Sattar, N; Hingorani, AD; (2009) C-Reactive Protein and Prognosis in Diabetes: Getting to the Heart of the Matter. DIABETES , 58 (4) 798 - 799. 10.2337/db08-1788.

Savvidou, MD; Hingorani, AD; Tsikas, D; Frolich, JC; Vallance, P; Nicolaides, KH; (2003) Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. LANCET , 361 (9368) 1511 - 1517.

Savvidou, MD; Lees, CC; Parra, M; Hingorani, AD; Nicolaides, KH; (2002) Levels of C-reactive protein in pregnant women who subsequently develop pre-eclampsia. BJOG-INT J OBSTET GY , 109 (3) 297 - 301.

Savvidou, MD; Noori, M; Anderson, JM; Hingorani, AD; Nicolaides, KH; (2008) Maternal endothelial function and serum concentrations of placental growth factor and soluble endoglin in women with abnormal placentation. ULTRASOUND OBST GYN , 32 (7) 871 - 876. 10.1002/uog.6126.

Savvidou, MD; Vallance, PJT; Nicolaides, KH; Hingorani, AD; (2001) Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy. HYPERTENSION , 38 (6) 1289 - 1293.

Savvidou, MD; Yu, CK; Harland, LC; Hingorani, AD; Nicolaides, KH; (2006) Maternal serum concentration of soluble fms-like tyrosine kinase 1 and vascular endothelial growth factor in women with abnormal uterine artery Doppler and in those with fetal growth restriction. AM J OBSTET GYNECOL , 195 (6) 1668 - 1673. 10.1016/j.ajog.2006.03.065.

Saxena, R; Elbers, CC; Guo, Y; Peter, I; Gaunt, TR; Mega, JL; Lanktree, MB; (2012) Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet , 90 (3) pp. 410-425. 10.1016/j.ajhg.2011.12.022.

Saxena, R; Hivert, MF; Langenberg, C; Tanaka, T; Pankow, JS; Vollenweider, P; Lyssenko, V; (2010) Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. NAT GENET , 42 (2) 142 - U75. 10.1038/ng.521.

Sayers, A; Timpson, NJ; Sattar, N; Deanfield, J; Hingorani, AD; Davey-Smith, G; Tobias, JH; (2010) Adiponectin and Its Association With Bone Mass Accrual in Childhood. J BONE MINER RES , 25 (10) 2212 - 2220. 10.1002/jbmr.116.

Serrano, NC; Casas, JP; Diaz, LA; Paez, C; Mesa, CM; Cifuentes, R; Monterrosa, A; (2004) Endothelial NO synthase genotype and risk of preeclampsia - A multicenter case-control study. HYPERTENSION , 44 (5) 702 - 707. 10.1161/01.HYP.0000143483.66701.ec.

Serrano, NC; Diaz, LA; Casas, JP; Hingorani, AD; de Lucca, DM; Paez, MC; (2010) Frequency of eNOS polymorphisms in the Colombian general population. BMC GENET , 11 , Article 54. 10.1186/1471-2156-11-54. Gold open access

Serrano, NC; Diaz, LA; Paez, MC; Mesa, CM; Cifuentes, R; Monterrosa, A; Gonzalez, A; (2006) Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: Evidence of small-study bias. PLoS Medicine , 3 (12) , Article e520. 10.1371/journal.pmed.0030520. Green open access
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Shah, AD; Nicholas, O; Timmis, AD; Feder, G; Abrams, KR; Chen, RL; Hingorani, AD; (2011) Threshold Haemoglobin Levels and the Prognosis of Stable Coronary Disease: Two New Cohorts and a Systematic Review and Meta-Analysis. PLoS Medicine , 8 (5) , Article e1000439. 10.1371/journal.pmed.1000439. Green open access
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Shah, S; Casas, JP; Drenos, F; Whittaker, J; Deanfield, J; Swerdlow, DI; Holmes, MV; (2013) Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis. Circ Cardiovasc Genet , 6 (1) pp. 63-72. 10.1161/CIRCGENETICS.112.963140.

Shah, S; Casas, JP; Gaunt, TR; Cooper, J; Drenos, F; Zabaneh, D; Swerdlow, DI; (2013) Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. Eur Heart J , 34 (13) 972 - 981. 10.1093/eurheartj/ehs243.

Shah, S; Casas, JP; Gaunt, TR; Cooper, J; Drenos, F; Zabaneh, D; Swerdlow, DI; (2013) Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. Eur Heart J , 34 (13) pp. 972-981. 10.1093/eurheartj/ehs243.

Shah, S; Nelson, CP; Gaunt, TR; van der Harst, P; Barnes, T; Braund, PS; Lawlor, DA; (2011) Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circ Cardiovasc Genet , 4 (6) pp. 626-635. 10.1161/CIRCGENETICS.111.960203.

Shah, T; Casas, JP; Cooper, JA; Tzoulaki, I; Sofat, R; McCormack, V; Smeeth, L; (2009) Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts (vol 38, pg 217, 2009). INT J EPIDEMIOL , 38 (3) 890 - 890. 10.1093/ije/dyp206.

Shah, T; Casas, JP; Cooper, JA; Tzoulaki, I; Sofat, R; McCormack, V; Smeeth, L; (2009) Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts. INT J EPIDEMIOL , 38 (1) 217 - 231. 10.1093/ije/dyn217.

Shah, T; Casas, JP; Cooper, JA; Tzoulaki, I; Sofat, R; Smeeth, L; Deanfield, JE; (2008) CRITICAL APPRAISAL OF THE UTILITY OF CRP MEASUREMENT IN THE PREDICTION OF CARDIOVASCULAR EVENTS. ATHEROSCLEROSIS SUPP , 9 (1) 10 - 10.

Shah, T; Engmann, J; Dale, C; Shah, S; White, J; Giambartolomei, C; McLachlan, S; (2013) Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS One , 8 (8) , Article e71345. 10.1371/journal.pone.0071345. Green open access
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Shah, T; Newcombe, P; Smeeth, L; Addo, J; Casas, JP; Whittaker, J; Miller, MA; (2010) Ancestry as a Determinant of Mean Population C-Reactive Protein Values Implications for Cardiovascular Risk Prediction. CIRC-CARDIOVASC GENE , 3 (5) 436 - U113. 10.1161/CIRCGENETICS.110.957431.

Shah, T; Zabaneh, D; Gaunt, T; Swerdlow, DI; Shah, S; Talmud, PJ; Day, IN; (2013) Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. Circ Cardiovasc Genet , 6 (2) pp. 163-170. 10.1161/CIRCGENETICS.112.964254.

Sharma, P; Hingorani, A; Jia, H; Ashby, M; Hopper, R; Clayton, D; Brown, MJ; (1998) Positive association of tyrosine hydro