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Number of items: 216.
Article
| UNSPECIFIED (2001) The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function Leeson CP,. Circulation , 102 (18) 1366 - ?. |
| Alves, JD and Clapp, BR and Stidwill, R and Chen, PP and Hingorani, AD and Singer, M and Isenberg, DA (2006) Human monoclonal IgG anticardiolipin antibodies induce nitric oxide synthase expression. ATHEROSCLEROSIS , 185 (2) 246 - 253. 10.1016/j.atherosclerosis.2005.06.044. |
| Angelakopoulou, A and Shah, T and Sofat, R and Shah, S and Berry, DJ and Cooper, J and Palmen, J and Tzoulaki, I and Wong, A and Jefferis, BJ and Maniatis, N and Drenos, F and Gigante, B and Hardy, R and Laxton, RC and Leander, K and Motterle, A and Simpson, IA and Smeeth, L and Thomson, A and Verzilli, C and Kuh, D and Ireland, H and Deanfield, J and Caulfield, M and Wallace, C and Samani, N and Munroe, PB and Lathrop, M and Fowkes, FG and Marmot, M and Whincup, PH and Whittaker, JC and de Faire, U and Kivimaki, M and Kumari, M and Hypponen, E and Power, C and Humphries, SE and Talmud, PJ and Price, J and Morris, RW and Ye, S and Casas, JP and Hingorani, AD (2012) Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J , 33 (3) 393 - 407. 10.1093/eurheartj/ehr225. |
| Ariyaratnam, R and Casas, JP and Whittaker, J and Smeeth, L and Hingorani, AD and Sharma, P (2007) Genetics of ischaemic stroke among persons of non-European descent: A meta-analysis of eight genes involving; 32,500 individuals. PLOS MED , 4 (4) , Article e131. 10.1371/journal.pmed.0040131. |
| Artigas, MS and Loth, DW and Wain, LV and Gharib, SA and Obeidat, M and Tang, WB and Zhai, GJ and Zhao, JH and Smith, AV and Huffman, JE and Albrecht, E and Jackson, CM and Evans, DM and Cadby, G and Fornage, M and Manichaikul, A and Lopez, LM and Johnson, T and Aldrich, MC and Aspelund, T and Barroso, I and Campbell, H and Cassano, PA and Couper, DJ and Eiriksdottir, G and Franceschini, N and Garcia, M and Gieger, C and Gislason, GK and Grkovic, I and Hammond, CJ and Hancock, DB and Harris, TB and Ramasamy, A and Heckbert, SR and Heliovaara, M and Homuth, G and Hysi, PG and Alan, L and Jankovic, S and Joubert, BR and Karrasch, S and Klopp, N and Koch, B and Kritchevsky, SB and Launer, LJ and Liu, YM and Loehr, LR and Lohman, K and Loos, RJF and Lumley, T and Al Balushi, KA and Ang, WQ and Barr, RG and Beilby, J and Blakey, JD and Boban, M and Boraska, V and Brisman, J and Britton, JR and Brusselle, GG and Cooper, C and Curjuric, I and Dahgam, S and Deary, IJ and Ebrahim, S and Eijgelsheim, M and Francks, C and Gaysina, D and Granell, R and Gu, XJ and Hankinson, JL and Hardy, R and Harris, SE and Henderson, J and Henry, A and Hingorani, AD and Hofman, A and Holt, PG and Hui, JN and Hunter, ML and Imboden, M and Jameson, KA and Kerr, SM and Kolcic, I and Kronenberg, F and Liu, JZ and Marchini, J and McKeever, T and Morris, AD and Olin, AC and Porteous, DJ and Postma, DS and Rich, SS and Ring, SM and Rivadeneira, F and Rochat, T and Sayer, AA and Sayers, I and Sly, PD and Smith, GD and Sood, A and Starr, JM and Uitterlinden, AG and Vonk, JM and Wannamethee, SG and Whincup, PH and Wijmenga, C and Williams, OD and Wong, A and Mangino, M and Marciante, KD and McArdle, WL and Meibohm, B and Morrison, AC and North, KE and Omenaas, E and Palmer, LJ and Pietilainen, KH and Pin, I and Polasek, O and Pouta, A and Psaty, BM and Hartikainen, AL and Rantanen, T and Ripatti, S and Rotter, JI and Rudan, I and Rudnicka, AR and Schulz, H and Shin, SY and Spector, TD and Surakka, I and Vitart, V and Volzke, H and Wareham, NJ and Warrington, NM and Wichmann, HE and Wild, SH and Wilk, JB and Wjst, M and Wright, AF and Zgaga, L and Zemunik, T and Pennell, CE and Nyberg, F and Kuh, D and Holloway, JW and Boezen, HM and Lawlor, DA and Morris, RW and Probst-Hensch, N and Kaprio, J and Wilson, JF and Hayward, C and Kahonen, M and Heinrich, J and Musk, AW and Jarvis, DL and Glaser, S and Jarvelin, MR and Stricker, BHC and Elliott, P and O'Connor, GT and Strachan, DP and London, SJ and Hall, IP and Gudnason, V and Tobin, MD and Int Lung Canc Consortium, and GIANT Consortium, (2011) Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. NAT GENET , 43 (11) 1082 - U70. 10.1038/ng.941. |
| Artigas, MS and Wain, LV and Repapi, E and Obeidat, M and Sayers, I and Burton, PR and Johnson, T and Zhao, JH and Albrecht, E and Dominiczak, AF and Kerr, SM and Smith, BH and Cadby, G and Hui, J and Palmer, LJ and Hingorani, AD and Wannamethee, SG and Whincup, PH and Ebrahim, S and Smith, GD and Barroso, I and Loos, RJF and Wareham, NJ and Cooper, C and Dennison, E and Shaheen, SO and Liu, JZ and Marchini, J and Dahgam, S and Naluai, AT and Olin, AC and Karrasch, S and Heinrich, J and Schulz, H and McKeever, TM and Pavord, ID and Heliovaara, M and Ripatti, S and Surakka, I and Blakey, JD and Kahonen, M and Britton, JR and Nyberg, F and Holloway, JW and Lawlor, DA and Morris, RW and James, AL and Jackson, CM and Hall, IP and Tobin, MD and Med Res Council Natl Survey Hlth D, and SpiroMeta Consortium, (2011) Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function. AM J RESP CRIT CARE , 184 (7) 786 - 795. 10.1164/rccm.201102-0192OC. |
| Asselbergs, FW and Guo, Y and van Iperen, EP and Sivapalaratnam, S and Tragante, V and Lanktree, MB and Lange, LA and Almoguera, B and Appelman, YE and Barnard, J and Baumert, J and Beitelshees, AL and Bhangale, TR and Chen, YD and Gaunt, TR and Gong, Y and Hopewell, JC and Johnson, T and Kleber, ME and Langaee, TY and Li, M and Li, YR and Liu, K and McDonough, CW and Meijs, MF and Middelberg, RP and Musunuru, K and Nelson, CP and O'Connell, JR and Padmanabhan, S and Pankow, JS and Pankratz, N and Rafelt, S and Rajagopalan, R and Romaine, SP and Schork, NJ and Shaffer, J and Shen, H and Smith, EN and Tischfield, SE and van der Most, PJ and van Vliet-Ostaptchouk, JV and Verweij, N and Volcik, KA and Zhang, L and Bailey, KR and Bailey, KM and Bauer, F and Boer, JM and Braund, PS and Burt, A and Burton, PR and Buxbaum, SG and Chen, W and Cooper-Dehoff, RM and Cupples, LA and deJong, JS and Delles, C and Duggan, D and Fornage, M and Furlong, CE and Glazer, N and Gums, JG and Hastie, C and Holmes, MV and Illig, T and Kirkland, SA and Kivimaki, M and Klein, R and Klein, BE and Kooperberg, C and Kottke-Marchant, K and Kumari, M and LaCroix, AZ and Mallela, L and Murugesan, G and Ordovas, J and Ouwehand, WH and Post, WS and Saxena, R and Scharnagl, H and Schreiner, PJ and Shah, T and Shields, DC and Shimbo, D and Srinivasan, SR and Stolk, RP and Swerdlow, DI and Taylor, HA and Topol, EJ and Toskala, E and van Pelt, JL and van Setten, J and Yusuf, S and Whittaker, JC and Zwinderman, AH and LifeLines Cohort Study, and Anand, SS and Balmforth, AJ and Berenson, GS and Bezzina, CR and Boehm, BO and Boerwinkle, E and Casas, JP and Caulfield, MJ and Clarke, R and Connell, JM and Cruickshanks, KJ and Davidson, KW and Day, IN and de Bakker, PI and Doevendans, PA and Dominiczak, AF and Hall, AS and Hartman, CA and Hengstenberg, C and Hillege, HL and Hofker, MH and Humphries, SE and Jarvik, GP and Johnson, JA and Kaess, BM and Kathiresan, S and Koenig, W and Lawlor, DA and März, W and Melander, O and Mitchell, BD and Montgomery, GW and Munroe, PB and Murray, SS and Newhouse, SJ and Onland-Moret, NC and Poulter, N and Psaty, B and Redline, S and Rich, SS and Rotter, JI and Schunkert, H and Sever, P and Shuldiner, AR and Silverstein, RL and Stanton, A and Thorand, B and Trip, MD and Tsai, MY and van der Harst, P and van der Schoot, E and van der Schouw, YT and Verschuren, WM and Watkins, H and Wilde, AA and Wolffenbuttel, BH and Whitfield, JB and Hovingh, GK and Ballantyne, CM and Wijmenga, C and Reilly, MP and Martin, NG and Wilson, JG and Rader, DJ and Samani, NJ and Reiner, AP and Hegele, RA and Kastelein, JJ and Hingorani, AD and Talmud, PJ and Hakonarson, H and Elbers, CC and Keating, BJ and Drenos, F (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet , 91 (5) 823 - 838. 10.1016/j.ajhg.2012.08.032. |
| Bautista, LE and Smeeth, L and Hingorani, AD and Casas, JP (2006) Estimation of bias in nongenetic observational studies using "Mendelian triangulation". ANN EPIDEMIOL , 16 (9) 675 - 680. 10.1016/j.annepidem.2006.02.001. |
| Bellamy, L and Casas, JP and Hingorani, AD and Williams, D (2009) Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. LANCET , 373 (9677) 1773 - 1779. |
| Bellamy, L and Casas, JP and Hingorani, AD and Williams, DJ (2007) Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BRIT MED J , 335 (7627) 974 - 977. 10.1136/bmj.39335.85301.BE. |
| Bellamy, L and Casas, JP and Hingorani, AD and Williams, DJ (2007) Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ , 335 (7627) 974 - ?. 10.1136/bmj.39335.385301.BE. |
| Berry, DJ and Vimaleswaran, KS and Whittaker, JC and Hingorani, AD and Hyppönen, E (2012) Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D. PLoS One , 7 (5) , Article e37465 . 10.1371/journal.pone.0037465. |  |
| Bessant, R and Hingorani, A and Patel, L and MacGregor, A and Isenberg, DA and Rahman, A (2004) Risk of coronary heart disease and stroke in a large British cohort of patients with systemic lupus erythematosus. RHEUMATOLOGY , 43 (7) 924 - 929. 10.1093/rheumatology/keh213. |
| Bhagat, K and Hingorani, A and Vallance, P (1997) Flow associated or flow mediated dilatation? More than just semantics. Heart , 78 (1) 7 - 8. |
| Bhagat, K and Hingorani, AD and Palacios, M and Charles, IG and Vallance, P (1999) Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS. CARDIOVASC RES , 41 (3) 754 - 764. |
| Brull, DJ and Serrano, N and Zito, F and Jones, L and Montgomery, HE and Rumley, A and Sharma, P and Lowe, GDO and World, MJ and Humphries, SE and Hingorani, AD (2003) Human CRP gene polymorphism influences CRP levels - Implications for the prediction and pathogenesis of coronary heart disease. ARTERIOSCL THROM VAS , 23 (11) 2063 - 2069. 10.1161/01.ATV.0000084640.21712.9C. |
| Brunner, EJ and Kivimaki, M and Witte, DR and Lawlor, DA and Smith, GD and Cooper, JA and Miller, M and Lowe, GDO and Rumley, A and Casas, JP and Shah, T and Humphries, SE and Hingorani, AD and Marmot, MG and Timpson, NJ and Kumari, M (2008) Inflammation, insulin resistance, and diabetes-mendelian randomization using CRP haplotypes points upstream. PLOS MED , 5 (8) , Article e155. 10.1371/journal.pmed.0050155. |
| Casas, JP and Bautista, LE and Humphries, SE and Hingorani, AD (2004) Endothelial nitric oxide synthase genotype and ischemic heart disease - Meta-analysis of 26 studies involving 23028 subjects. CIRCULATION , 109 (11) 1359 - 1365. 10.1161/01.CIR.0000121357.76910.A3. |
| Casas, JP and Bautista, LE and Smeeth, L and Sharma, P and Hingorani, AD (2005) Homocysteine and stroke: evidence on a causal link from mendelian randomisation. LANCET , 365 (9455) 224 - 232. |
| Casas, JP and Cavalleri, GL and Bautista, LE and Smeeth, L and Humphries, SE and Hingorani, AD (2006) Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: A HuGE review. AM J EPIDEMIOL , 164 (10) 921 - 935. 10.1093/aje/kwj302. |
| Casas, JP and Chua, WL and Loukogeorgakis, S and Vallance, P and Smeeth, L and Hingorani, AD and MacAllister, RJ (2005) Effect of inhibitors of the renin-angiotensin system and other anti hypertensive drugs on renal outcomes: systematic review and meta-analysis. LANCET , 366 (9502) 2026 - 2033. |
| Casas, JP and Cooper, J and Miller, GJ and Hingorani, AD and Humphries, SE (2006) Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies. ANN HUM GENET , 70 145 - 169. 10.1111/j.1469-1809.2005.00241.x. |
| Casas, JP and Hingorani, AD and Bautista, LE and Sharma, P (2004) Meta-analysis of genetic studies in ischemic stroke - Thirty-two genes involving approximately 18 000 cases and 58 000 controls. ARCH NEUROL-CHICAGO , 61 (11) 1652 - 1661. |
| Casas, JP and Hingorani, AD and Humphries, SE and Smeeth, L and Bautista, LE (2004) Do meta-analyses of association studies of endothelial nitric oxide synthase variants and ischemic heart disease provide conclusive answers? Response. CIRCULATION , 110 (11) E305 - E306. |
| Casas, JP and Hingorani, AD and MacAllister, RJ and Smeeth, L (2006) Progression of renal disease - can we forget about inhibition of the renin-angiotensin system? Authors' reply. NEPHROL DIAL TRANSPL , 21 (9) 2352 - 2353. 10.1093/ndt/gfl316. |
| Casas, JP and Ninio, E and Panayiotou, A and Palmen, J and Cooper, JA and Ricketts, SL and Sofat, R and Nicolaides, AN and Corsetti, JP and Fowkes, FGR and Tzoulaki, I and Kumari, M and Brunner, EJ and Kivimaki, M and Marmot, MG and Hoffmann, MM and Winkler, K and Marz, W and Ye, S and Stirnadel, HA and Boekholdt, SM and Khaw, KT and Humphries, SE and Sandhu, MS and Hingorani, AD and Talmud, PJ (2010) PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A2 Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry (vol 121, pg 2284, 2010). CIRCULATION , 122 (3) E400 - E400. 10.1161/CIR.0b013e3181eb187c. |
| Casas, JP and Ninio, E and Panayiotou, A and Palmen, J and Cooper, JA and Ricketts, SL and Sofat, R and Nicolaides, AN and Corsetti, JP and Fowkes, FGR and Tzoulaki, I and Kumari, M and Brunner, EJ and Kivimaki, M and Marmot, MG and Hoffmann, MM and Winkler, K and Marz, W and Ye, S and Stirnadel, HA and Khaw, KT and Humphries, SE and Sandhu, MS and Hingorani, AD and Talmud, PJ (2010) PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A(2) Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry. CIRCULATION , 121 (21) 2284 - U74. 10.1161/CIRCULATIONAHA.109.923383. |
| Casas, JP and Shah, T and Cooper, J and Hawe, E and McMahon, AD and Gaffney, D and Packard, CJ and O'Reilly, DS and Juhan-Vague, I and Yudkin, JS and Tremoli, E and Margaglione, M and Di Minno, G and Hamsten, A and Kooistra, T and Stephens, JW and Hurel, SJ and Livingstone, S and Colhoun, HM and Miller, GJ and Bautista, LE and Meade, T and Sattar, N and Humphries, SE and Hingorani, AD (2006) Insight into the nature of the CRP-coronary event association using Mendelian randomization. INT J EPIDEMIOL , 35 (4) 922 - 931. 10.1093/ije/dyl041. |
| Casas, JP and Shah, T and Hingorani, AD and Danesh, J and Pepys, MB (2008) C-reactive protein and coronary heart disease: a critical review. J INTERN MED , 264 (4) 295 - 314. 10.1111/j.1365-2796.2008.02015.x. |
| Casas, JP and Vallance, P and Smeeth, L and Hingorani, AD and MacAllister, RJ (2006) Renoprotective effects of renin-angiotensin-system inhibitors - Reply. LANCET , 367 (9514) 900 - 902. |
| Chakravarthy, U and McKay, GJ and de Jong, PT and Rahu, M and Seland, J and Soubrane, G and Tomazzoli, L and Topouzis, F and Vingerling, JR and Vioque, J and Young, IS and Sofat, R and Hingorani, AD and Fletcher, AE (2013) ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study. Ophthalmology , 120 (2) 342 - 348. 10.1016/j.ophtha.2012.08.004. |
| Chan, NN and MacAllister, RJ and Colhoun, HM and Vallance, P and Hingorani, AD (2001) Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. J CLIN ENDOCR METAB , 86 (6) 2499 - 2504. |
| Chan, NN and Vallance, P and Colhoun, HM and MacAllister, RJ and Hingorani, AD and Conway, GS (2002) The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome. CLIN ENDOCRINOL , 56 (5) 615 - 620. |
| Chan, NN and Vallance, PJ and Macallister, RJ and Hingorani, AD and Colhoun, HM (2000) Impaired nitric oxide response in resistance vessels in human type 1 diabetes in vivo. CIRCULATION , 102 (18) 326 - 326. |
| Chen, Z and Ahluwalia, A and Selwood, DL and Vallance, P and Hingorani, AD (1999) Enhancement of endothelium-dependent vasodilatation by oestradiol 17-beta: Role of the pterin pathway. BRIT J PHARMACOL , 126 U32 - U32. |
| Clapp, BR and Hingorani, AD and Kharbanda, RK and Mohamed-Ali, V and Stephens, JW and Vallance, P and MacAllister, RJ (2004) Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. CARDIOVASC RES , 64 (1) 172 - 178. 10.1016/j.cardiores.2004.06.020. |
| Clapp, BR and Hirschfield, GM and Storry, C and Gallimore, JR and Stidwill, RP and Singer, M and Deanfield, JE and MacAllister, RJ and Pepys, MB and Vallance, P and Hingorani, AD (2005) Inflammation and endothelial function - Direct vascular effects of human C-reactive protein on nitric oxide bioavailability. CIRCULATION , 111 (12) 1530 - 1536. 10.1161/01.CIR.0000159336.31613.31. |
| Clarke, R and Emberson, JR and Breeze, E and Casas, JP and Parish, S and Hingorani, AD and Fletcher, A and Collins, R and Smeeth, L (2008) Biomarkers of inflammation predict both vascular and non-vascular mortality in older men. EUR HEART J , 29 (6) 800 - 809. 10.1093/eurheartj/ehn049. |
| Costelloe, SJ and El-Sayed Moustafa, JS and Drenos, F and Palmen, J and Li, Q and Whiting, S and Thomas, M and Kivimaki, M and Kumari, M and Hingorani, AD and Tzoulaki, I and Järvelin, MR and Ruokonen, A and Hartikainen, AL and Pouta, A and Walters, RG and Blakemore, AI and Humphries, SE and Coin, LJ and Talmud, PJ (2012) Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits. Circ Cardiovasc Genet , 5 (5) 555 - 560. 10.1161/CIRCGENETICS.111.961037. |
| D'Aiuto, F and Casas, JP and Shah, T and Humphries, SE and Hingorani, AD and Tonetti, MS (2005) C-reactive protein (+1444C > T) polymorphism influences CRP response following a moderate inflammatory stimulus. ATHEROSCLEROSIS , 179 (2) 413 - 417. 10.1016/j.atherosclerosis.2004.10.036. |
| D'Aiuto, F and Sabbah, W and Netuveli, G and Donos, N and Hingorani, AD and Deanfield, J and Tsakos, G (2008) Association of the metabolic syndrome with severe periodontitis in a large US population-based survey. J CLIN ENDOCR METAB , 93 (10) 3989 - 3994. 10.1210/jc.2007-2522. |
| Dastani, Z and Hivert, MF and Timpson, N and Perry, JR and Yuan, X and Scott, RA and Henneman, P and Heid, IM and Kizer, JR and Lyytikäinen, LP and Fuchsberger, C and Tanaka, T and Morris, AP and Small, K and Isaacs, A and Beekman, M and Coassin, S and Lohman, K and Qi, L and Kanoni, S and Pankow, JS and Uh, HW and Wu, Y and Bidulescu, A and Rasmussen-Torvik, LJ and Greenwood, CM and Ladouceur, M and Grimsby, J and Manning, AK and Liu, CT and Kooner, J and Mooser, VE and Vollenweider, P and Kapur, KA and Chambers, J and Wareham, NJ and Langenberg, C and Frants, R and Willems-Vandijk, K and Oostra, BA and Willems, SM and Lamina, C and Winkler, TW and Psaty, BM and Tracy, RP and Brody, J and Chen, I and Viikari, J and Kähönen, M and Pramstaller, PP and Evans, DM and St Pourcain, B and Sattar, N and Wood, AR and Bandinelli, S and Carlson, OD and Egan, JM and Böhringer, S and van Heemst, D and Kedenko, L and Kristiansson, K and Nuotio, ML and Loo, BM and Harris, T and Garcia, M and Kanaya, A and Haun, M and Klopp, N and Wichmann, HE and Deloukas, P and Katsareli, E and Couper, DJ and Duncan, BB and Kloppenburg, M and Adair, LS and Borja, JB and DIAGRAM+ Consortium, and MAGIC Consortium, and GLGC Investigators, and MuTHER Consortium, and Wilson, JG and Musani, S and Guo, X and Johnson, T and Semple, R and Teslovich, TM and Allison, MA and Redline, S and Buxbaum, SG and Mohlke, KL and Meulenbelt, I and Ballantyne, CM and Dedoussis, GV and Hu, FB and Liu, Y and Paulweber, B and Spector, TD and Slagboom, PE and Ferrucci, L and Jula, A and Perola, M and Raitakari, O and Florez, JC and Salomaa, V and Eriksson, JG and Frayling, TM and Hicks, AA and Lehtimäki, T and Smith, GD and Siscovick, DS and Kronenberg, F and van Duijn, C and Loos, RJ and Waterworth, DM and Meigs, JB and Dupuis, J and Richards, JB and Voight, BF and Scott, LJ and Steinthorsdottir, V and Dina, C and Welch, RP and Zeggini, E and Huth, C and Aulchenko, YS and Thorleifsson, G and McCulloch, LJ and Ferreira, T and Grallert, H and Amin, N and Wu, G and Willer, CJ and Raychaudhuri, S and McCarroll, SA and Hofmann, OM and Segrè, AV and van Hoek, M and Navarro, P and Ardlie, K and Balkau, B and Benediktsson, R and Bennett, AJ and Blagieva, R and Boerwinkle, E and Bonnycastle, LL and Boström, KB and Bravenboer, B and Bumpstead, S and Burtt, NP and Charpentier, G and Chines, PS and Cornelis, M and Crawford, G and Doney, AS and Elliott, KS and Elliott, AL and Erdos, MR and Fox, CS and Franklin, CS and Ganser, M and Gieger, C and Grarup, N and Green, T and Griffin, S and Groves, CJ and Guiducci, C and Hadjadj, S and Hassanali, N and Herder, C and Isomaa, B and Jackson, AU and Johnson, PR and Jørgensen, T and Kao, WH and Kong, A and Kraft, P and Kuusisto, J and Lauritzen, T and Li, M and Lieverse, A and Lindgren, CM and Lyssenko, V and Marre, M and Meitinger, T and Midthjell, K and Morken, MA and Narisu, N and Nilsson, P and Owen, KR and Payne, F and Petersen, AK and Platou, C and Proença, C and Prokopenko, I and Rathmann, W and Rayner, NW and Robertson, NR and Rocheleau, G and Roden, M and Sampson, MJ and Saxena, R and Shields, BM and Shrader, P and Sigurdsson, G and Sparsø, T and Strassburger, K and Stringham, HM and Sun, Q and Swift, AJ and Thorand, B and Tichet, J and Tuomi, T and van Dam, RM and van Haeften, TW and van Herpt, T and van Vliet-Ostaptchouk, JV and Walters, GB and Weedon, MN and Wijmenga, C and Witteman, J and Bergman, RN and Cauchi, S and Collins, FS and Gloyn, AL and Gyllensten, U and Hansen, T and Hide, WA and Hitman, GA and Hofman, A and Hunter, DJ and Hveem, K and Laakso, M and Morris, AD and Palmer, CN and Rudan, I and Sijbrands, E and Stein, LD and Tuomilehto, J and Uitterlinden, A and Walker, M and Watanabe, RM and Abecasis, GR and Boehm, BO and Campbell, H and Daly, MJ and Hattersley, AT and Pedersen, O and Barroso, I and Groop, L and Sladek, R and Thorsteinsdottir, U and Wilson, JF and Illig, T and Froguel, P and van Duijn, CM and Stefansson, K and Altshuler, D and Boehnke, M and McCarthy, MI and Soranzo, N and Wheeler, E and Glazer, NL and Bouatia-Naji, N and Mägi, R and Randall, J and Elliott, P and Rybin, D and Dehghan, A and Hottenga, JJ and Song, K and Goel, A and Lajunen, T and Doney, A and Cavalcanti-Proença, C and Kumari, M and Timpson, NJ and Zabena, C and Ingelsson, E and An, P and O'Connell, J and Luan, J and Elliott, A and McCarroll, SA and Roccasecca, RM and Pattou, F and Sethupathy, P and Ariyurek, Y and Barter, P and Beilby, JP and Ben-Shlomo, Y and Bergmann, S and Bochud, M and Bonnefond, A and Borch-Johnsen, K and Böttcher, Y and Brunner, E and Bumpstead, SJ and Chen, YD and Chines, P and Clarke, R and Coin, LJ and Cooper, MN and Crisponi, L and Day, IN and de Geus, EJ and Delplanque, J and Fedson, AC and Fischer-Rosinsky, A and Forouhi, NG and Franzosi, MG and Galan, P and Goodarzi, MO and Graessler, J and Grundy, S and Gwilliam, R and Hallmans, G and Hammond, N and Han, X and Hartikainen, AL 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Charchar, FJ and Schwarz, PEH and Hayward, C and Guo, XQ and Rotimi, C and Bots, ML and Brand, E and Samani, NJ and Polasek, O and Talmud, PJ and Nyberg, F and Kuh, D and Laan, M and Hveem, K and Palmer, LJ and van der Schouw, YT and Casas, JP and Mohlke, KL and Vineis, P and Raitakari, O and Ganesh, SK and Wong, TY and Tai, ES and Cooper, RS and Laakso, M and Rao, DC and Harris, TB and Morris, RW and Dominiczak, AF and Kivimaki, M and Marmot, MG and Miki, T and Saleheen, D and Chandak, GR and Coresh, J and Navis, G and Salomaa, V and Han, BG and Zhu, XF and Kooner, JS and Melander, O and Ridker, PM and Bandinelli, S and Gyllensten, UB and Wright, AF and Wilson, JF and Ferrucci, L and Farrall, M and Tuomilehto, J and Pramstaller, PP and Elosua, R and Soranzo, N and Sijbrands, EJG and Altshuler, D and Loos, RJF and Shuldiner, AR and Gieger, C and Meneton, P and Uitterlinden, AG and Wareham, NJ and Gudnason, V and Rotter, JI and Rettig, R and Uda, M and Strachan, DP and Witteman, JCM and Hartikainen, AL and Beckmann, JS and Boerwinkle, E and Vasan, RS and Boehnke, M and Larson, MG and Jarvelin, MR and Psaty, BM and Abecasis, GR and Chakravarti, A and Elliott, P and van Duijn, CM and Newton-Cheh, C and Levy, D and Caulfield, MJ and Johnson, T and Int Consortium Blood Pressure Geno, and CARDIoGRAM Consortium, and CKDGen Consortium, and KidneyGen Consortium, and EchoGen Consortium, and CHARGE-HF Consortium, (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. NATURE , 478 (7367) 103 - 109. 10.1038/nature10405. |
| Falaschetti, E and Hingorani, AD and Jones, A and Charakida, M and Finer, N and Whincup, P and Lawlor, DA and Smith, GD and Sattar, N and Deanfield, JE (2010) Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children. EUR HEART J , 31 (24) 3063 - 3072. 10.1093/eurheartj/ehq355. |
| Fox, ER and Young, JH and Li, Y and Dreisbach, AW and Keating, BJ and Musani, SK and Liu, K and Morrison, AC and Ganesh, S and Kutlar, A and Ramachandran, VS and Polak, JF and Fabsitz, RR and Dries, DL and Farlow, DN and Redline, S and Adeyemo, A and Hirschorn, JN and Sun, YV and Wyatt, SB and Penman, AD and Palmas, W and Rotter, JI and Townsend, RR and Doumatey, AP and Tayo, BO and Mosley, TH and Lyon, HN and Kang, SJ and Rotimi, CN and Cooper, RS and Franceschini, N and Curb, JD and Martin, LW and Eaton, CB and Kardia, SL and Taylor, HA and Caulfield, MJ and Ehret, GB and Johnson, T and International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), and Chakravarti, A and Zhu, X and Levy, D (2011) Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet , 20 (11) 2273 - 2284. 10.1093/hmg/ddr092. |
| Freathy, RM and Kazeem, GR and Morris, RW and Johnson, PC and Paternoster, L and Ebrahim, S and Hattersley, AT and Hill, A and Hingorani, AD and Holst, C and Jefferis, BJ and Kring, SI and Mooser, V and Padmanabhan, S and Preisig, M and Ring, SM and Sattar, N and Upton, MN and Vollenweider, P and Waeber, G and Sørensen, TI and Frayling, TM and Watt, G and Lawlor, DA and Whincup, PH and Tozzi, F and Davey Smith, G and Munafò, M (2011) Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. Int J Epidemiol , 40 (6) 1617 - 1628. 10.1093/ije/dyr077. |
| Gaunt, TR and Shah, S and Nelson, CP and Drenos, F and Braund, PS and Adeniran, I and Folkersen, L and Lawlor, DA and Casas, JP and Amuzu, A and Kivimaki, M and Whittaker, J and Eriksson, P and Zhang, H and Hancox, JC and Tomaszewski, M and Burton, PR and Tobin, MD and Humphries, SE and Talmud, PJ and Macfarlane, PW and Hingorani, AD and Samani, NJ and Kumari, M and Day, IN (2012) Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip. Circ Cardiovasc Genet , 5 (6) 630 - 638. 10.1161/CIRCGENETICS.112.962852. |
| Gertow, K and Sennblad, B and Strawbridge, RJ and Ohrvik, J and Zabaneh, D and Shah, S and Veglia, F and Fava, C and Kavousi, M and McLachlan, S and Kivimäki, M and Bolton, JL and Folkersen, L and Gigante, B and Leander, K and Vikström, M and Larsson, M and Silveira, A and Deanfield, J and Voight, BF and Fontanillas, P and Sabater-Lleal, M and Colombo, GI and Kumari, M and Langenberg, C and Wareham, NJ and Uitterlinden, AG and Gabrielsen, A and Hedin, U and Franco-Cereceda, A and Nyyssönen, K and Rauramaa, R and Tuomainen, TP and Savonen, K and Smit, AJ and Giral, P and Mannarino, E and Robertson, CM and Talmud, PJ and Hedblad, B and Hofman, A and Erdmann, J and Reilly, MP and O'Donnell, CJ and Farrall, M and Clarke, R and Franzosi, MG and Seedorf, U and Syvänen, AC and Hansson, GK and Eriksson, P and Samani, NJ and Watkins, H and Price, JF and Hingorani, AD and Melander, O and Witteman, JC and Baldassarre, D and Tremoli, E and de Faire, U and Humphries, SE and Hamsten, A (2012) Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. Circ Cardiovasc Genet , 5 (6) 656 - 665. 10.1161/CIRCGENETICS.112.963660. |
| Grosso, A and Douglas, I and Hingorani, A and MacAllister, R and Smeeth, L (2008) Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions. BRIT J CLIN PHARMACO , 66 (5) 689 - 694. 10.1111/j.1365-2125.2008.03273.x. |
| Grosso, A and Douglas, I and Hingorani, AD and MacAllister, R and Hubbard, R and Smeeth, L (2009) Inhaled tiotropium bromide and risk of stroke. BRIT J CLIN PHARMACO , 68 (5) 731 - 736. 10.1111/j.1365-2125.2009.03517.x. |
| Grosso, A and Douglas, I and MacAllister, R and Petersen, I and Smeeth, L and Hingorani, AD (2011) Use of the self-controlled case series method in drug safety assessment. EXPERT OPIN DRUG SAF , 10 (3) 337 - 340. 10.1517/14740338.2011.562187. |
| Grosso, AM and Bodalia, PN and MacAllister, RJ and Hingorani, AD and Moon, JC and Scott, MA (2011) Cost-saving opportunities and angiotensin-II receptor blocker prescribing. INT J CLIN PRACT , 65 (8) 912 - 912. 10.1111/j.1742-1241.2011.02730.x. |
| Grosso, AM and Bodalia, PN and MacAllister, RJ and Hingorani, AD and Moon, JC and Scott, MA (2011) Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis. INT J CLIN PRACT , 65 (3) 253 - 263. 10.1111/j.1742-1241.2011.02633.x. |
| Harrison, SC and Smith, AJ and Jones, GT and Swerdlow, DI and Rampuri, R and Bown, MJ and on behalf of the Aneurysm Consortium, and Folkersen, L and Baas, AF and de Borst, GJ and Blankensteijn, JD and Price, JF and van der Graaf, Y and McLachlan, S and Agu, O and Hofman, A and Uitterlinden, AG and Franco-Cereceda, A and Ruigrok, YM and Van't Hof, FN and Powell, JT and van Rij, AM and Casas, JP and Eriksson, P and Holmes, MV and Asselbergs, FW and Hingorani, AD and Humphries, SE (2012) Interleukin-6 receptor pathways in abdominal aortic aneurysm. Eur Heart J 10.1093/eurheartj/ehs354. |
| Harrison, SC and Zabaneh, D and Asselbergs, FW and Drenos, F and Jones, GT and Shah, S and Gertow, K and Sennblad, B and Strawbridge, RJ and Gigante, B and Holewijn, S and De Graaf, J and Vermeulen, S and Folkersen, L and van Rij, AM and Baldassarre, D and Veglia, F and Talmud, PJ and Deanfield, JE and Agu, O and Kivimaki, M and Kumari, M and Bown, MJ and Nyyssönen, K and Rauramaa, R and Smit, AJ and Franco-Cereceda, A and Giral, P and Mannarino, E and Silveira, A and Syvänen, AC and de Borst, GJ and van der Graaf, Y and de Faire, U and Baas, AF and Blankensteijn, JD and Wareham, NJ and Fowkes, G and Tzoulaki, I and Price, JF and Tremoli, E and Hingorani, AD and Eriksson, P and Hamsten, A and Humphries, SE (2013) A gene-centric study of common carotid artery remodelling. Atherosclerosis , 226 (2) 440 - 446. 10.1016/j.atherosclerosis.2012.11.002. |
| Healy, DG and Abou-Sleiman, PM and Lees, AJ and Casas, JP and Quinn, N and Bhatia, K and Hingorani, AD and Wood, NW (2004) Tau gene and Parkinson's disease: a case-control study and meta-analysis. J NEUROL NEUROSUR PS , 75 (7) 962 - 965. 10.1136/jnnp.2003.026203. |
| Hemingway, H and Philipson, P and Chen, RL and Fitzpatrick, NK and Damant, J and Shipley, M and Abrams, KR and Moreno, S and McAllister, KSL and Palmer, S and Kaski, JC and Timmis, AD and Hingorani, AD (2010) Evaluating the Quality of Research into a Single Prognostic Biomarker: A Systematic Review and Meta-analysis of 83 Studies of C-Reactive Protein in Stable Coronary Artery Disease. PLOS MED , 7 (6) , Article e1000286. 10.1371/journal.pmed.1000286. |
| Henriksson, M and Palmer, S and Chen, RL and Damant, J and Fitzpatrick, NK and Abrams, K and Hingorani, AD and Stenestrand, U and Janzon, M and Feder, G and Keogh, B and Shipley, MJ and Kaski, JC and Timmis, A and Sculpher, M and Hemingway, H (2010) Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery. BRIT MED J , 340 , Article b5606. 10.1136/bmj.b5606. |
| Hingorani, A (2004) Resolving inconsistency in the results of genetic association studies of cardiovascular disease. Clinical Science , 107 (3) 251 - 253. |
| Hingorani, AD (2004) Diet, the endothelium and atherosclerosis. CLIN SCI , 106 (5) 447 - 448. 10.1042/CS20040023. |
| Hingorani, AD (2003) Endothelial nitric oxide synthase polymorphisms and hypertension. CURR HYPERTENS REP , 5 (1) 19 - 25. |
| Hingorani, AD (2001) Polymorphisms in endothelial nitric oxide synthase and atherogenesis - John French Lecture 2000. ATHEROSCLEROSIS , 154 (3) 521 - 527. |
| HINGORANI, AD (1993) THE FLOSEQUINAN EXPERIENCE AND ITS IMPLICATIONS. BRIT J HOSP MED , 50 (11) 683 - 683. |
| Hingorani, AD (1992) Postinfectious myocarditis. BMJ , 304 (6843) 1676 - 1678. |
| Hingorani, AD and Bhagat, K and Palacios, M and Griffin, GE and MacAllister, RJ and Vallance, P (1999) Acute systemic inflammation impairs endothelium-dependent dilatation in humans. BRIT J PHARMACOL , 126 U31 - U31. |
| HINGORANI, AD and BLOOMBERG, TJ (1995) ULTRASOUND-GUIDED PIGTAIL CATHETER DRAINAGE OF MALIGNANT PERICARDIAL-EFFUSIONS. CLIN RADIOL , 50 (1) 15 - 19. |
| Hingorani, AD and Brown, MJ (1996) Identifying the genes for human hypertension. NEPHROL DIAL TRANSPL , 11 (4) 575 - 586. |
| Hingorani, AD and Brown, MJ (1996) A simple molecular assay for the C-1166 variant of the angiotensin II type 1 receptor gene (vol 213, pg 725, 1995). BIOCHEM BIOPH RES CO , 218 (1) 420 - 420. |
| HINGORANI, AD and BROWN, MJ (1995) A SIMPLE MOLECULAR ASSAY FOR THE C-1166 VARIANT OF THE ANGIOTENSIN-II TYPE-1 RECEPTOR GENE. BIOCHEM BIOPH RES CO , 213 (2) 725 - 729. |
| Hingorani, AD and Chan, NN (2001) D-lactate encephalopathy. LANCET , 358 (9295) 1814 - 1814. |
| Hingorani, AD and Cross, J and Kharbanda, RK and Mullen, MJ and Bhagat, K and Taylor, M and Donald, AE and Palacios, M and Griffin, GE and Deanfield, JE and MacAllister, RJ and Vallance, P (2000) Acute systemic inflammation impairs endothelium-dependent dilatation in humans. CIRCULATION , 102 (9) 994 - 999. |
| Hingorani, AD and Cross, JM and Kharbanda, RK and Mullen, MJ and Bhagat, K and Taylor, M and Donald, AE and Palacios-Callende, M and Griffin, GE and Deanfield, JE and Raymond, MJ and Vallance, P (1999) Acute systemic inflammation impairs endothelium-dependent dilation in humans. CIRCULATION , 100 (18) 48 - 48. |
| Hingorani, AD and D'Aiuto, F (2008) Chronic inflammation, periodontitis and cardiovascular diseases. ORAL DIS , 14 (2) 102 - 104. 10.1111/j.1601-0825.2007.01439.x. |
| HINGORANI, AD and DOLLERY, CT and OAKLEY, CM and BLOOM, SR and COHEN, J (1992) HAMMERSMITH STAFF ROUNDS - POSTINFECTIOUS MYOCARDITIS. BRIT MED J , 304 (6843) 1676 - 1678. |
| HINGORANI, AD and FOLEY, TH (1995) NONSUSTAINED BROAD-COMPLEX TACHYCARDIA FOLLOWING INTRAVENOUS ADENOSINE. J ACCID EMERG MED , 12 (3) 208 - 209. |
| Hingorani, AD and Hemingway, H (2011) How should we balance individual and population benefits of statins for preventing cardiovascular disease? BRIT MED J , 342 , Article c6244. 10.1136/bmj.c6244. |
| Hingorani, AD and Jia, HY and Stevens, PA and Hopper, R and Dickerson, JEC and Brown, MJ (1995) Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition. JOURNAL OF HYPERTENSION , 13 (12) 1602 - 1609. |
| HINGORANI, AD and JONES, AT and DZIERSK, J and GOLDINGWOOD, D and LEIGH, JM (1994) ADULT EPIGLOTTITIS - ESTABLISH AN AIRWAY EARLY. BRIT MED J , 308 (6930) 719 - 719. |
| Hingorani, AD and Liang, CF and Fatibene, J and Lyon, A and Monteith, S and Parsons, A and Haydock, S and Hopper, RV and Stephens, NG and O'Shaughnessy, KM and Brown, MJ (1999) A common variant of the endothelial nitric oxide synthase (Glu(298)-> Asp) is a major risk factor for coronary artery disease in the UK. CIRCULATION , 100 (14) 1515 - 1520. |
| Hingorani, AD and Liang, CF and Fatibene, J and Parsons, A and Hopper, RV and Trutwein, D and Stephens, NG and OShaughnessy, KM and Brown, MJ (1997) A common variant of the endothelial nitric oxide synthase gene is a risk factor for coronary atherosclerosis in the east Anglian region of the UK. CIRCULATION , 96 (8) 3050 - 3050. |
| HINGORANI, AD and MACDOUGALL, IC and BROWNE, M and WALKER, RWH and TOMSON, CRV (1993) SUCCESSFUL TREATMENT OF ACUTE D-LACTATE ENCEPHALOPATHY BY HEMODIALYSIS. NEPHROL DIAL TRANSPL , 8 (11) 1283 - 1285. |
| Hingorani, AD and OHanlon, S and Halloran, SP and Wright, JP and Foley, TH (1997) Evaluation of a paired creatine kinase test for the diagnosis of acute myocardial infarction in patients with a non-diagnostic electrocardiogram. J ACCID EMERG MED , 14 (3) 134 - 138. |
| Hingorani, AD and Psaty, BM (2010) Modeling Cardiovascular Disease Prevention Reply. JAMA-J AM MED ASSOC , 303 (9) 835 - 835. |
| Hingorani, AD and Psaty, BM (2009) Primary Prevention of Cardiovascular Disease Time to Get More or Less Personal? JAMA-J AM MED ASSOC , 302 (19) 2144 - 2145. |
| Hingorani, AD and Shah, T and Casas, JP (2006) Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk. EUR HEART J , 27 (11) 1261 - 1263. 10.1193/eurheart/ehl852. |
| Hingorani, AD and Shah, T and Casas, JP (2006) Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk. Eur Heart J , 27 (11) 1261 - 1263. 10.1093/eurheartj/ehi852. |
| Hingorani, AD and Shah, T and Casas, JP and Humphries, SE and Talmud, PJ (2009) C-Reactive Protein and Coronary Heart Disease: Predictive Test or Therapeutic Target? CLIN CHEM , 55 (2) 239 - 255. 10.1373/clinchem.2008.115923. |
| Hingorani, AD and Shah, T and Kumari, M and Sofat, R and Smeeth, L (2010) Science, medicine, and the future Translating genomics into improved healthcare. BRIT MED J , 341 , Article c5945. 10.1136/bmj.c5945. |
| Hingorani, AD and Shah, T and Kumari, M and Sofat, R and Smeeth, L (2010) Translating genomics into improved healthcare. BMJ , 341 c5945 - ?. |
| Hingorani, AD and Sharma, P and Jia, HY and Hopper, R and Brown, MJ (1996) Blood pressure and the M235T polymorphism of the angiotensinogen gene. HYPERTENSION , 28 (5) 907 - 911. |
| Hingorani, AD and Sofat, R and Morris, RW and Whincup, P and Lowe, GD and Mindell, J and Sattar, N and Casas, JP and Shah, T (2012) Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease? Eur Heart J , 33 (18) 2258 - 2264. 10.1093/eurheartj/ehs168. |
| Hingorani, AD and Vallance, P (1999) Hypothesis of program is flawed - Reply. BRIT MED J , 318 (7195) 1419 - 1419. |
| Hingorani, AD and Vallance, P (1999) A simple computer program for guiding management of cardiovascular risk factors and prescribing. BRIT MED J , 318 (7176) 101 - 105. |
| HINGORANI, AD and WAINSWORTH, RW (1993) PULMONARY MICROEMBOLIZATION AND TEMAZEPAM. BRIT MED J , 307 (6904) 623 - 624. |
| Holmes, MV and Casas, JP and Hingorani, AD (2011) Putting genomics into practice. BRIT MED J , 343 , Article d4953. 10.1136/bmj.d4953. |
| Holmes, MV and Harrison, S and Talmud, PJ and Hingorani, AD and Humphries, SE (2011) Utility of genetic determinants of lipids and cardiovascular events in assessing risk. NAT REV CARDIOL , 8 (4) 207 - 221. 10.1038/nrcardio.2011.6. |
| Holmes, MV and Hingorani, AD and Casas, JP (2012) CYP2C19 Genotype and Cardiovascular Events Reply. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION , 307 (14) 1484 - 1485. |
| Holmes, MV and Newcombe, P and Hubacek, JA and Sofat, R and Ricketts, SL and Cooper, J and Breteler, MMB and Bautista, LE and Sharma, P and Whittaker, JC and Smeeth, L and Fowkes, FGR and Algra, A and Shmeleva, V and Szolnoki, Z and Roest, M and Linnebank, M and Zacho, J and Nalls, MA and Singleton, AB and Ferrucci, L and Hardy, J and Worrall, BB and Rich, SS and Matarin, M and Norman, PE and Flicker, L and Almeida, OP and van Bockxmeer, FM and Shimokata, H and Khaw, KT and Wareham, NJ and Bobak, M and Sterne, JAC and Smith, GD and Talmud, PJ and van Duijn, C and Humphries, SE and Price, JF and Ebrahim, S and Lawlor, DA and Hankey, GJ and Meschia, JF and Sandhu, MS and Hingorani, AD and Casas, JP (2011) Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. LANCET , 378 (9791) 584 - 594. 10.1016/S0140-6736(11)60872-6. |
| Holmes, MV and Perel, P and Shah, T and Hingorani, AD and Casas, JP (2011) CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis. JAMA , 306 (24) 2704 - 2714. 10.1001/jama.2011.1880. |
| Holmes, MV and Shah, T and Vickery, C and Smeeth, L and Hingorani, AD and Casas, JP (2009) Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies. PLOS ONE , 4 (12) , Article e7960. 10.1371/journal.pone.0007960. | |
| Howe, LD and Galobardes, B and Sattar, N and Hingorani, AD and Deanfield, J and Ness, AR and Davey-Smith, G and Lawlor, DA (2010) Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study. INT J OBESITY , 34 (7) 1149 - 1159. 10.1038/ijo.2010.52. |
| Hu, Y and Li, L and Ehm, MG and Bing, N and Song, K and Nelson, MR and Talmud, PJ and Hingorani, AD and Kumari, M and Kivimäki, M and Xu, CF and Waterworth, DM and Whittaker, JC and Abecasis, GR and Spino, C and Kang, HM (2013) The benefits of using genetic information to design prevention trials. Am J Hum Genet , 92 (4) 547 - 557. 10.1016/j.ajhg.2013.03.003. |
| Humphries, SE and Hingorani, A (2006) Pharmacogenetics: Progress, pitfalls and clinical potential for coronary heart disease. VASC PHARMACOL , 44 (2) 119 - 125. 10.1016/j.vph.2005.10.003. |
| Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium, and Hingorani, AD and Casas, JP (2012) The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet , 379 (9822) 1214 - 1224. 10.1016/S0140-6736(12)60110-X. |
| International Consortium for Blood Pressure Genome-Wide Association Studies, and Ehret, GB and Munroe, PB and Rice, KM and Bochud, M and Johnson, AD and Chasman, DI and Smith, AV and Tobin, MD and Verwoert, GC and Hwang, SJ and Pihur, V and Vollenweider, P and O'Reilly, PF and Amin, N and Bragg-Gresham, JL and Teumer, A and Glazer, NL and Launer, L and Zhao, JH and Aulchenko, Y and Heath, S and Sõber, S and Parsa, A and Luan, J and Arora, P and Dehghan, A and Zhang, F and Lucas, G and Hicks, AA and Jackson, AU and Peden, JF and Tanaka, T and Wild, SH and Rudan, I and Igl, W and Milaneschi, Y and Parker, AN and Fava, C and Chambers, JC and Fox, ER and Kumari, M and Go, MJ and van der Harst, P and Kao, WH and Sjögren, M and Vinay, DG and Alexander, M and Tabara, Y and Shaw-Hawkins, S and Whincup, PH and Liu, Y and Shi, G and Kuusisto, J and Tayo, B and Seielstad, M and Sim, X and Nguyen, KD and Lehtimäki, T and Matullo, G and Wu, Y and Gaunt, TR and Onland-Moret, NC and Cooper, MN and Platou, CG and Org, E and Hardy, R and Dahgam, S and Palmen, J and Vitart, V and Braund, PS and Kuznetsova, T and Uiterwaal, CS and Adeyemo, A and Palmas, W and Campbell, H and Ludwig, B and Tomaszewski, M and Tzoulaki, I and Palmer, ND and CARDIoGRAM consortium, and CKDGen Consortium, and KidneyGen Consortium, and EchoGen consortium, and CHARGE-HF consortium, and Aspelund, T and Garcia, M and Chang, YP and O'Connell, JR and Steinle, NI and Grobbee, DE and Arking, DE and Kardia, SL and Morrison, AC and Hernandez, D and Najjar, S and McArdle, WL and Hadley, D and Brown, MJ and Connell, JM and Hingorani, AD and Day, IN and Lawlor, DA and Beilby, JP and Lawrence, RW and Clarke, R and Hopewell, JC and Ongen, H and Dreisbach, AW and Li, Y and Young, JH and Bis, JC and Kähönen, M and Viikari, J and Adair, LS and Lee, NR and Chen, MH and Olden, M and Pattaro, C and Bolton, JA and Köttgen, A and Bergmann, S and Mooser, V and Chaturvedi, N and Frayling, TM and Islam, M and Jafar, TH and Erdmann, J and Kulkarni, SR and Bornstein, SR and Grässler, J and Groop, L and Voight, BF and Kettunen, J and Howard, P and Taylor, A and Guarrera, S and Ricceri, F and Emilsson, V and Plump, A and Barroso, I and Khaw, KT and Weder, AB and Hunt, SC and Sun, YV and Bergman, RN and Collins, FS and Bonnycastle, LL and Scott, LJ and Stringham, HM and Peltonen, L and Perola, M and Vartiainen, E and Brand, SM and Staessen, JA and Wang, TJ and Burton, PR and Soler Artigas, M and Dong, Y and Snieder, H and Wang, X and Zhu, H and Lohman, KK and Rudock, ME and Heckbert, SR and Smith, NL and Wiggins, KL and Doumatey, A and Shriner, D and Veldre, G and Viigimaa, M and Kinra, S and Prabhakaran, D and Tripathy, V and Langefeld, CD and Rosengren, A and Thelle, DS and Corsi, AM and Singleton, A and Forrester, T and Hilton, G and McKenzie, CA and Salako, T and Iwai, N and Kita, Y and Ogihara, T and Ohkubo, T and Okamura, T and Ueshima, H and Umemura, S and Eyheramendy, S and Meitinger, T and Wichmann, HE and Cho, YS and Kim, HL and Lee, JY and Scott, J and Sehmi, JS and Zhang, W and Hedblad, B and Nilsson, P and Smith, GD and Wong, A and Narisu, N and Stančáková, A and Raffel, LJ and Yao, J and Kathiresan, S and O'Donnell, CJ and Schwartz, SM and Ikram, MA and Longstreth, WT and Mosley, TH and Seshadri, S and Shrine, NR and Wain, LV and Morken, MA and Swift, AJ and Laitinen, J and Prokopenko, I and Zitting, P and Cooper, JA and Humphries, SE and Danesh, J and Rasheed, A and Goel, A and Hamsten, A and Watkins, H and Bakker, SJ and van Gilst, WH and Janipalli, CS and Mani, KR and Yajnik, CS and Hofman, A and Mattace-Raso, FU and Oostra, BA and Demirkan, A and Isaacs, A and Rivadeneira, F and Lakatta, EG and Orru, M and Scuteri, A and Ala-Korpela, M and Kangas, AJ and Lyytikäinen, LP and Soininen, P and Tukiainen, T and Würtz, P and Ong, RT and Dörr, M and Kroemer, HK and Völker, U and Völzke, H and Galan, P and Hercberg, S and Lathrop, M and Zelenika, D and Deloukas, P and Mangino, M and Spector, TD and Zhai, G and Meschia, JF and Nalls, MA and Sharma, P and Terzic, J and Kumar, MV and Denniff, M and Zukowska-Szczechowska, E and Wagenknecht, LE and Fowkes, FG and Charchar, FJ and Schwarz, PE and Hayward, C and Guo, X and Rotimi, C and Bots, ML and Brand, E and Samani, NJ and Polasek, O and Talmud, PJ and Nyberg, F and Kuh, D and Laan, M and Hveem, K and Palmer, LJ and van der Schouw, YT and Casas, JP and Mohlke, KL and Vineis, P and Raitakari, O and Ganesh, SK and Wong, TY and Tai, ES and Cooper, RS and Laakso, M and Rao, DC and Harris, TB and Morris, RW and Dominiczak, AF and Kivimaki, M and Marmot, MG and Miki, T and Saleheen, D and Chandak, GR and Coresh, J and Navis, G and Salomaa, V and Han, BG and Zhu, X and Kooner, JS and Melander, O and Ridker, PM and Bandinelli, S and Gyllensten, UB and Wright, AF and Wilson, JF and Ferrucci, L and Farrall, M and Tuomilehto, J and Pramstaller, PP and Elosua, R and Soranzo, N and Sijbrands, EJ and Altshuler, D and Loos, RJ and Shuldiner, AR and Gieger, C and Meneton, P and Uitterlinden, AG and Wareham, NJ and Gudnason, V and Rotter, JI and Rettig, R and Uda, M and Strachan, DP and Witteman, JC and Hartikainen, AL and Beckmann, JS and Boerwinkle, E and Vasan, RS and Boehnke, M and Larson, MG and Järvelin, MR and Psaty, BM and Abecasis, GR and Chakravarti, A and Elliott, P and van Duijn, CM and Newton-Cheh, C and Levy, D and Caulfield, MJ and Johnson, T (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. 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| Jeerooburkhan, N and Jones, LC and Bujac, S and Cooper, JA and Miller, GJ and Vallance, P and Humphries, SE and Hingorani, AD (2001) Genetic and environmental determinants of plasma nitrogen oxides and risk of ischemic heart disease. HYPERTENSION , 38 (5) 1054 - 1061. |
| Jensen, AC and Barker, A and Kumari, M and Brunner, EJ and Kivimaki, M and Hingorani, AD and Wareham, NJ and Tabak, AG and Witte, DR and Langenberg, C (2011) Associations of Common Genetic Variants With Age-Related Changes in Fasting and Postload Glucose Evidence From 18 Years of Follow-Up of the Whitehall II Cohort. DIABETES , 60 (5) 1617 - 1623. 10.2337/db10-1393. |
| Jia, HY and Hingorani, AD and Sharma, P and Hopper, R and Dickerson, C and Trutwein, D and Lloyd, DD and Brown, MJ (1999) Association of the G(s)alpha gene with essential hypertension and response to beta-blockade. HYPERTENSION , 34 (1) 8 - 14. |
| Johnson, T and Gaunt, TR and Newhouse, SJ and Padmanabhan, S and Tomaszewski, M and Kumari, M and Morris, RW and Tzoulaki, I and O'Brien, ET and Poulter, NR and Sever, P and Shields, DC and Thom, S and Wannamethee, SG and Whincup, PH and Brown, MJ and Connell, JM and Dobson, RJ and Howard, PJ and Mein, CA and Onipinla, A and Shaw-Hawkins, S and Zhang, Y and Davey Smith, G and Day, IN and Lawlor, DA and Goodall, AH and Cardiogenics Consortium, and Fowkes, FG and Abecasis, GR and Elliott, P and Gateva, V and Global BPgen Consortium, and Braund, PS and Burton, PR and Nelson, CP and Tobin, MD and van der Harst, P and Glorioso, N and Neuvrith, H and Salvi, E and Staessen, JA and Stucchi, A and Devos, N and Jeunemaitre, X and Plouin, PF and Tichet, J and Juhanson, P and Org, E and Putku, M and Sõber, S and Veldre, G and Viigimaa, M and Levinsson, A and Rosengren, A and Thelle, DS and Hastie, CE and Hedner, T and Lee, WK and Melander, O and Wahlstrand, B and Hardy, R and Wong, A and Cooper, JA and Palmen, J and Chen, L and Stewart, AF and Wells, GA and Westra, HJ and Wolfs, MG and Clarke, R and Franzosi, MG and Goel, A and Hamsten, A and Lathrop, M and Peden, JF and Seedorf, U and Watkins, H and Ouwehand, WH and Sambrook, J and Stephens, J and Casas, JP and Drenos, F and Holmes, MV and Kivimaki, M and Shah, S and Shah, T and Talmud, PJ and Whittaker, J and Wallace, C and Delles, C and Laan, M and Kuh, D and Humphries, SE and Nyberg, F and Cusi, D and Roberts, R and Newton-Cheh, C and Franke, L and Stanton, AV and Dominiczak, AF and Farrall, M and Hingorani, AD and Samani, NJ and Caulfield, MJ and Munroe, PB (2011) Blood pressure loci identified with a gene-centric array. Am J Hum Genet , 89 (6) 688 - 700. 10.1016/j.ajhg.2011.10.013. |
| Jones, A and Charakida, M and Falaschetti, E and Hingorani, AD and Finer, N and Masi, S and Donald, AE and Lawlor, DA and Smith, GD and Deanfield, JE (2012) Adipose and height growth through childhood and blood pressure status in a large prospective cohort study. Hypertension , 59 (5) 919 - 925. 10.1161/HYPERTENSIONAHA.111.187716. |
| Jones, LC and Hingorani, AD (2005) Genetic regulation of endothelial function. HEART , 91 (10) 1275 - 1277. 10.1136/hrt.2005.061325. |
| Jones, LC and Tran, CTL and Leiper, JM and Hingorani, AD and Vallance, P (2003) Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells. BIOCHEM BIOPH RES CO , 310 (3) 836 - 843. 10.1016/j.bbrc.2003.09.097. |
| Ken-Dror, G and Drenos, F and Humphries, SE and Talmud, PJ and Hingorani, AD and Kivimaki, M and Kumari, M and Bauer, KA and Morrissey, JH and Ireland, HA (2010) Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men. J THROMB HAEMOST , 8 (11) 2394 - 2403. 10.1111/j.1538-7836.2010.04035.x. |
| Kharbanda, RK and Walton, B and Allen, M and Klein, N and Hingorani, AD and MacAllister, RJ and Vallance, P (2002) Prevention of inflammation-induced endothelial dysfunction - A novel vasculo-protective action of aspirin. CIRCULATION , 105 (22) 2600 - 2604. 10.1161/01.CIR.0000017863.52347.6C. |
| Kivimaki, M and Lawlor, DA and Smith, GD and Kumari, M and Donald, A and Britton, A and Casas, JP and Shah, T and Brunner, E and Timpson, NJ and Halcox, JPJ and Miller, MA and Humphries, SE and Deanfield, J and Marmot, MG and Hingorani, AD (2008) Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study. PLOS ONE , 3 (8) , Article e3013. 10.1371/journal.pone.0003013. | |
| Kuper, H and Nicholson, A and Kivimaki, M and Aitsi-Selmi, A and Cavalleri, G and Deanfield, JE and Heuschmann, P and Jouven, X and Malyutina, S and Mayosi, BM and Sans, S and Thomsen, T and Witteman, JCM and Hingorani, AD and Lawlor, DA and Hemingway, H (2009) Evaluating the causal relevance of diverse risk markers: horizontal systematic review. BRIT MED J , 339 , Article b4265. 10.1136/bmj.b4265. |
| Lanktree, MB and Guo, YR and Murtaza, M and Glessner, JT and Bailey, SD and Onland-Moret, NC and Lettre, G and Ongen, H and Rajagopalan, R and Johnson, T and Shen, HQ and Nelson, CP and Klopp, N and Baumert, J and Padmanabhan, S and Pankratz, N and Pankow, JS and Shah, S and Taylor, K and Barnard, J and Peters, BJ and Maloney, CM and Lobmeyer, MT and Stanton, A and Zafarmand, MH and Romaine, SPR and Mehta, A and van Iperen, EPA and Gong, Y and Price, TS and Smith, EN and Kim, CE and Li, YR and Asselbergs, FW and Atwood, LD and Bailey, KM and Bhatt, D and Bauer, F and Behr, ER and Bhangale, T and Boer, JMA and Boehm, BO and Bradfield, JP and Brown, M and Braund, PS and Burton, PR and Carty, C and Chandrupatla, HR and Chen, W and Connell, J and Dalgeorgou, C and de Boer, A and Drenos, F and Elbers, CC and Fang, JC and Fox, CS and Frackelton, EC and Fuchs, B and Furlong, CE and Gibson, Q and Gieger, C and Goe, A and Grobbee, DE and Hastie, C and Howard, PJ and Huang, GH and Johnson, WC and Li, Q and Kleber, ME and Klein, BEK and Klein, R and Kooperberg, C and Ky, B and LaCroix, A and Lanken, P and Lathrop, M and Li, MY and Marshal, V and Melander, O and Mentch, FD and Meyer, NJ and Monda, KL and Montpetit, A and Murugesan, G and Nakayama, K and Nondah, D and Onipinla, A and Rafelt, S and Newhouse, SJ and Otieno, FG and Patel, SR and Putt, ME and Rodriguez, S and Safa, RN and Sawyer, DB and Schreiner, PJ and Simpson, C and Sivapalaratnam, S and Srinivasan, SR and Suver, C and Swergold, G and Sweitzer, NK and Thomas, KA and Thorand, B and Timpson, NJ and Tischfield, S and Tobin, M and Tomaszweski, M and Verschuren, WMM and Wallace, C and Winkelmann, B and Zhang, HT and Zheng, DL and Zhang, L and Zmuda, JM and Clarke, R and Balmforth, AJ and Danesh, J and Day, IN and Schork, NJ and de Bakker, PIW and Delles, C and Duggan, D and Hingorani, AD and Hirschhorn, JN and Hofker, MH and Humphries, SE and Kivimaki, M and Lawlor, DA and Kottke-Marchant, K and Mega, JL and Mitchell, BD and Morrow, DA and Palmen, J and Redline, S and Shields, DC and Shuldiner, AR and Sleiman, PM and Smith, GD and Farrall, M and Jamshidi, Y and Christiani, DC and Casas, JP and Hall, AS and Doevendans, PA and Christie, JD and Berenson, GS and Murray, SS and Illig, T and Dorn, GW and Cappola, TP and Boerwinkle, E and Sever, P and Rader, DJ and Reilly, MP and Caulfield, M and Talmud, PJ and Topol, E and Engert, JC and Wang, K and Dominiczak, A and Hamsten, A and Curtis, SP and Silverstein, RL and Lange, LA and Sabatine, MS and Trip, M and Saleheen, D and Peden, JF and Cruickshanks, KJ and Marz, W and O'Connell, JR and Klungel, OH and Wijmenga, C and Maitland-van der Zee, AH and Schadt, EE and Johnson, JA and Jarvik, GP and Papanicolaou, GJ and Watkins, H and Grant, SFA and Munroe, PB and North, KE and Samani, NJ and Koenig, W and Gaunt, TR and Anand, SS and van der Schouw, YT and Kumari, M and Soranzo, N and FitzGerald, GA and Reiner, A and Hegele, RA and Hakonarson, H and Keating, BJ and PROCARDIS, and Whitehall II Study, and WHII 50K Grp, (2011) Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. AM J HUM GENET , 88 (1) 6 - 18. 10.1016/j.ajhg.2010.11.007. |
| Leeson, CP and Hingorani, AD and Mullen, MJ and Jeerooburkhan, N and Kattenhorn, M and Muller, DP and Lucas, A and Humphries, SE and Deanfield, JE (2000) The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. CIRCULATION , 102 (18) 279 - 279. |
| Leeson, CPM and Hingorani, AD and Mullen, MJ and Jeerooburkhan, N and Kattenhorn, M and Cole, TJ and Muller, DPR and Lucas, A and Humphries, SE and Deanfield, JE (2002) Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. CIRC RES , 90 (11) 1153 - 1158. 10.1161/01.RES.0000020562.07492.D4. |
| MacAllister, R and Hingorani, AD and Casas, JP (2004) Ximelagatran or warfarin in atrial fibrillation? LANCET , 363 (9410) 735 - 736. |
| Mayahi, L and Heales, S and Owen, D and Casas, JP and Harris, J and MacAllister, RJ and Hingorani, AD (2007) (6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm. ARTERIOSCL THROM VAS , 27 (6) 1334 - 1339. 10.1161/ATVBAHA.107.142257. |
| Mayahi, L and Mason, L and Bleasdale-Barr, K and Donald, A and Trender-Gerhard, I and Sweeney, MG and Davis, MB and Wood, N and Mathias, CJ and Watson, L and Pellerin, D and Heales, S and Deanfield, JE and Bhatia, K and Murray-Rust, J and Hingorani, AD (2010) Endothelial, Sympathetic, and Cardiac Function in Inherited (6R)-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin Deficiency. CIRC-CARDIOVASC GENE , 3 (6) 513 - 522. 10.1161/CIRCGENETICS.110.957605. |
| Mayahi, L and Mason, L and Storry, C and Donald, A and Trender-Gherhard, I and Mathias, C and Deanfield, J and Bhatia, K and Heales, S and Pellerin, D and Hingorani, A (2006) Endothelial, sympathetic and cardiac function in inherited 6R-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin deficiency. CIRCULATION , 114 (18) 283 - 283. |
| McKay, GJ and Patterson, CC and Chakravarthy, U and Dasari, S and Klaver, CC and Vingerling, JR and Ho, L and de Jong, PT and Fletcher, AE and Young, IS and Seland, JH and Rahu, M and Soubrane, G and Tomazzoli, L and Topouzis, F and Vioque, J and Hingorani, AD and Sofat, R and Dean, M and Sawitzke, J and Seddon, JM and Peter, I and Webster, AR and Moore, AT and Yates, JR and Cipriani, V and Fritsche, LG and Weber, BH and Keilhauer, CN and Lotery, AJ and Ennis, S and Klein, ML and Francis, PJ and Stambolian, D and Orlin, A and Gorin, MB and Weeks, DE and Kuo, CL and Swaroop, A and Othman, M and Kanda, A and Chen, W and Abecasis, GR and Wright, AF and Hayward, C and Baird, PN and Guymer, RH and Attia, J and Thakkinstian, A and Silvestri, G (2011) Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat , 32 (12) 1407 - 1416. 10.1002/humu.21577. |
| McKay, GJ and Silvestri, G and Chakravarthy, U and Dasari, S and Fritsche, LG and Weber, BH and Keilhauer, CN and Klein, ML and Francis, PJ and Klaver, CC and Vingerling, JR and Ho, L and De Jong, PTDV and Dean, M and Sawitzke, J and Baird, PN and Guymer, RH and Stambolian, D and Orlin, A and Seddon, JM and Peter, I and Wright, AF and Hayward, C and Lotery, AJ and Ennis, S and Gorin, MB and Weeks, DE and Kuo, CL and Hingorani, AD and Sofat, R and Cipriani, V and Swaroop, A and Othman, M and Kanda, A and Chen, W and Abecasis, GR and Yates, JR and Webster, AR and Moore, AT and Seland, JH and Rahu, M and Soubrane, G and Tomazzoli, L and Topouzis, F and Vioque, J and Young, IS and Fletcher, AE and Patterson, CC (2011) Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People. AM J EPIDEMIOL , 173 (12) 1357 - 1364. 10.1093/aje/kwr015. |
| Minassian, C and D'Aiuto, F and Hingorani, AD (2011) Invasive Dental Treatment and Risk for Vascular Events RESPONSE. ANN INTERN MED , 154 (6) 442 - 442. 10.1059/0003-4819-154-6-201103150-00016. |
| Minassian, C and D'Aiuto, F and Hingorani, AD and Smeeth, L (2010) Invasive Dental Treatment and Risk for Vascular Events A Self-Controlled Case Series. ANN INTERN MED , 153 (8) 499 - W181. |
| Munafò, MR and Timofeeva, MN and Morris, RW and Prieto-Merino, D and Sattar, N and Brennan, P and Johnstone, EC and Relton, C and Johnson, PC and Walther, D and Whincup, PH and Casas, JP and Uhl, GR and Vineis, P and Padmanabhan, S and Jefferis, BJ and Amuzu, A and Riboli, E and Upton, MN and Aveyard, P and Ebrahim, S and Hingorani, AD and Watt, G and Palmer, TM and Timpson, NJ and EPIC Study Group, and Davey Smith, G (2012) Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. J Natl Cancer Inst , 104 (10) 740 - 748. 10.1093/jnci/djs191. |
| Newcombe, PJ and Verzilli, C and Casas, JP and Hingorani, AD and Smeeth, L and Whittaker, JC (2009) Multilocus Bayesian Meta-Analysis of Gene-Disease Associations. AM J HUM GENET , 84 (5) 567 - 580. 10.1016/j.ajhg.2009.04.001. |
| Noori, M and Donald, AE and Angelakopoulou, A and Hingorani, AD and Williams, DJ (2010) Prospective Study of Placental Angiogenic Factors and Maternal Vascular Function Before and After Preeclampsia and Gestational Hypertension. CIRCULATION , 122 (5) 478 - 487. 10.1161/CIRCULATIONAHA.109.895458. |
| O'Neill, SG and Pego-Reigosa, JM and Hingorani, AD and Bessant, R and Isenberg, DA and Rahman, A (2009) Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus. RHEUMATOLOGY , 48 (5) 573 - 575. 10.1093/rheumatology/kep037. |
| Palmer, ND and McDonough, CW and Hicks, PJ and Roh, BH and Wing, MR and An, SS and Hester, JM and Cooke, JN and Bostrom, MA and Rudock, ME and Talbert, ME and Lewis, JP and DIAGRAM Consortium, and MAGIC Investigators, and Ferrara, A and Lu, L and Ziegler, JT and Sale, MM and Divers, J and Shriner, D and Adeyemo, A and Rotimi, CN and Ng, MC and Langefeld, CD and Freedman, BI and Bowden, DW and Voight, BF and Scott, LJ and Steinthorsdottir, V and Morris, AP and Dina, C and Welch, RP and Zeggini, E and Huth, C and Aulchenko, YS and Thorleifsson, G and McCulloch, LJ and Ferreira, T and Grallert, H and Amin, N and Wu, G and Willer, CJ and Raychaudhuri, S and McCarroll, SA and Langenberg, C and Hofmann, OM and Dupuis, J and Qi, L and Segrè, AV and van Hoek, M and Navarro, P and Ardlie, K and Balkau, B and Benediktsson, R and Bennett, AJ and Blagieva, R and Boerwinkle, E and Bonnycastle, LL and Boström, KB and Bravenboer, B and Bumpstead, S and Burtt, NP and Charpentier, G and Chines, PS and Cornelis, M and Couper, DJ and Crawford, G and Doney, AS and Elliott, KS and Elliott, AL and Erdos, MR and Fox, CS and Franklin, CS and Ganser, M and Gieger, C and Grarup, N and Green, T and Griffin, S and Groves, CJ and Guiducci, C and Hadjadj, S and Hassanali, N and Herder, C and Isomaa, B and Jackson, AU and Johnson, PR and Jørgensen, T and Kao, WH and Klopp, N and Kong, A and Kraft, P and Kuusisto, J and Lauritzen, T and Li, M and Lieverse, A and Lindgren, CM and Lyssenko, V and Marre, M and Meitinger, T and Midthjell, K and Morken, MA and Narisu, N and Nilsson, P and Owen, KR and Payne, F and Perry, JR and Petersen, AK and Platou, C and Proença, C and Prokopenko, I and Rathmann, W and Rayner, NW and Robertson, NR and Rocheleau, G and Roden, M and Sampson, MJ and Saxena, R and Shields, BM and Shrader, P and Sigurdsson, G and Sparsø, T and Strassburger, K and Stringham, HM and Sun, Q and Swift, AJ and Thorand, B and Tichet, J and Tuomi, T and van Dam, RM and van Haeften, TW and 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| Smeeth, L and Casas, JP and Hingorani, AD (2007) The role of infection in cardiovascular disease: more support but many questions remain. Eur Heart J , 28 (10) 1178 - 1179. 10.1093/eurheartj/ehm073. |
| Smeeth, L and Hingorani, AD (2010) Short-term vascular risk: time to take notice? NAT REV CARDIOL , 7 (7) 409 - 412. 10.1038/nrcardio.2010.64. |
| Smith, AJ and Howard, P and Shah, S and Eriksson, P and Stender, S and Giambartolomei, C and Folkersen, L and Tybjærg-Hansen, A and Kumari, M and Palmen, J and Hingorani, AD and Talmud, PJ and Humphries, SE (2012) Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays. PLoS Genet , 8 (8) e1002908 - ?. 10.1371/journal.pgen.1002908. |
| Sofat, R and Casas, JP and Grosso, AM and Prichard, BN and Smeeth, L and MacAllister, R and Hingorani, AD (2012) Could NICE guidance on the choice of blood pressure lowering drugs be simplified? BMJ , 344 d8078 - ?. |
| Sofat, R and Casas, JP and Grosso, AM and Prichard, BNC and Smeeth, L and MacAllister, R and Hingorani, AD (2012) Could NICE guidance on the choice of blood pressure lowering drugs be simplified? BRITISH MEDICAL JOURNAL , 344 , Article ARTN d8078. 10.1136/bmj.d8078. |
| Sofat, R and Casas, JP and Kumari, M and Talmud, PJ and Ireland, H and Kivimaki, M and Marmot, M and Hughes, AD and Thom, S and Ebrahim, S and Whittaker, JC and Smeeth, L and Lawlor, DA and Humphries, SE and Hingorani, AD (2010) Genetic variation in complement factor H and risk of coronary heart disease: Eight new studies and a meta-analysis of around 48,000 individuals. ATHEROSCLEROSIS , 213 (1) 184 - 190. 10.1016/j.atherosclerosis.2010.07.021. |
| Sofat, R and Casas, JP and Webster, AR and Bird, AC and Mann, SS and Yates, JR and Moore, AT and Sepp, T and Cipriani, V and Bunce, C and Khan, JC and Shahid, H and Swaroop, A and Abecasis, G and Branham, KE and Zareparsi, S and Bergen, AA and Klaver, CC and Baas, DC and Zhang, K and Chen, Y and Gibbs, D and Weber, BH and Keilhauer, CN and Fritsche, LG and Lotery, A and Cree, AJ and Griffiths, HL and Bhattacharya, SS and Chen, LL and Jenkins, SA and Peto, T and Lathrop, M and Leveillard, T and Gorin, MB and Weeks, DE and Ortube, MC and Ferrell, RE and Jakobsdottir, J and Conley, YP and Rahu, M and Seland, JH and Soubrane, G and Topouzis, F and Vioque, J and Tomazzoli, L and Young, I and Whittaker, J and Chakravarthy, U and de Jong, PT and Smeeth, L and Fletcher, A and Hingorani, AD (2012) Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype. Int J Epidemiol , 41 (1) 250 - 262. 10.1093/ije/dyr204. |
| Sofat, R and Hingorani, AD and Smeeth, L and Humphries, SE and Talmud, PJ and Cooper, J and Shah, T and Sandhu, MS and Ricketts, SL and Boekholdt, SM and Wareham, N and Khaw, KT and Kumari, M and Kivimaki, M and Marmot, M and Asselbergs, FW and van der Harst, P and Dullaart, RPF and Navis, G and van Veldhuisen, DJ and Van Gilst, WH and Thompson, JF and McCaskie, P and Palmer, LJ and Arca, M and Quagliarini, F and Gaudio, C and Cambien, F and Nicaud, V and Poirer, O and Gudnason, V and Isaacs, A and Witteman, JCM and van Duijn, CM and Pencina, M and Vasan, RS and D'Agostino, RB and Ordovas, J and Li, TY and Kakko, S and Kauma, H and Savolainen, MJ and Kesaniemi, YA and Sandhofer, A and Paulweber, B and Sorli, JV and Goto, A and Yokoyama, S and Okumura, K and Horne, BD and Packard, C and Freeman, D and Ford, I and Sattar, N and McCormack, V and Lawlor, DA and Ebrahim, S and Smith, GD and Kastelein, JJP and Deanfield, J and Casas, JP (2010) Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms. CIRCULATION , 121 (1) 52 - 62. 10.1161/CIRCULATIONAHA.109.865444. |
| Soler Artigas, M and Loth, DW and Wain, LV and Gharib, SA and Obeidat, M and Tang, W and Zhai, G and Zhao, JH and Smith, AV and Huffman, JE and Albrecht, E and Jackson, CM and Evans, DM and Cadby, G and Fornage, M and Manichaikul, A and Lopez, LM and Johnson, T and Aldrich, MC and Aspelund, T and Barroso, I and Campbell, H and Cassano, PA and Couper, DJ and Eiriksdottir, G and Franceschini, N and Garcia, M and Gieger, C and Gislason, GK and Grkovic, I and Hammond, CJ and Hancock, DB and Harris, TB and Ramasamy, A and Heckbert, SR and Heliövaara, M and Homuth, G and Hysi, PG and James, AL and Jankovic, S and Joubert, BR and Karrasch, S and Klopp, N and Koch, B and Kritchevsky, SB and Launer, LJ and Liu, Y and Loehr, LR and Lohman, K and Loos, RJ and Lumley, T and Al Balushi, KA and Ang, WQ and Barr, RG and Beilby, J and Blakey, JD and Boban, M and Boraska, V and Brisman, J and Britton, JR and Brusselle, GG and Cooper, C and Curjuric, I and Dahgam, S and Deary, IJ and Ebrahim, S and Eijgelsheim, M and Francks, C and Gaysina, D and Granell, R and Gu, X and Hankinson, JL and Hardy, R and Harris, SE and Henderson, J and Henry, A and Hingorani, AD and Hofman, A and Holt, PG and Hui, J and Hunter, ML and Imboden, M and Jameson, KA and Kerr, SM and Kolcic, I and Kronenberg, F and Liu, JZ and Marchini, J and McKeever, T and Morris, AD and Olin, AC and Porteous, DJ and Postma, DS and Rich, SS and Ring, SM and Rivadeneira, F and Rochat, T and Sayer, AA and Sayers, I and Sly, PD and Smith, GD and Sood, A and Starr, JM and Uitterlinden, AG and Vonk, JM and Wannamethee, SG and Whincup, PH and Wijmenga, C and Williams, OD and Wong, A and Mangino, M and Marciante, KD and McArdle, WL and Meibohm, B and Morrison, AC and North, KE and Omenaas, E and Palmer, LJ and Pietiläinen, KH and Pin, I and Pola Sbreve Ek, O and Pouta, A and Psaty, BM and Hartikainen, AL and Rantanen, T and Ripatti, S and Rotter, JI and Rudan, I and Rudnicka, AR and Schulz, H and Shin, SY and Spector, TD and Surakka, I and Vitart, V and Völzke, H and Wareham, NJ and Warrington, NM and Wichmann, HE and Wild, SH and Wilk, JB and Wjst, M and Wright, AF and Zgaga, L and Zemunik, T and Pennell, CE and Nyberg, F and Kuh, D and Holloway, JW and Boezen, HM and Lawlor, DA and Morris, RW and Probst-Hensch, N and International Lung Cancer Consortium, and GIANT consortium, and Kaprio, J and Wilson, JF and Hayward, C and Kähönen, M and Heinrich, J and Musk, AW and Jarvis, DL and Gläser, S and Järvelin, MR and Ch Stricker, BH and Elliott, P and O'Connor, GT and Strachan, DP and London, SJ and Hall, IP and Gudnason, V and Tobin, MD (2011) Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet , 43 (11) 1082 - 1090. 10.1038/ng.941. |
| Soler Artigas, M and Wain, LV and Repapi, E and Obeidat, M and Sayers, I and Burton, PR and Johnson, T and Zhao, JH and Albrecht, E and Dominiczak, AF and Kerr, SM and Smith, BH and Cadby, G and Hui, J and Palmer, LJ and Hingorani, AD and Wannamethee, SG and Whincup, PH and Ebrahim, S and Smith, GD and Barroso, I and Loos, RJ and Wareham, NJ and Cooper, C and Dennison, E and Shaheen, SO and Liu, JZ and Marchini, J and Medical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team, and Dahgam, S and Naluai, AT and Olin, AC and Karrasch, S and Heinrich, J and Schulz, H and McKeever, TM and Pavord, ID and Heliövaara, M and Ripatti, S and Surakka, I and Blakey, JD and Kähönen, M and Britton, JR and Nyberg, F and Holloway, JW and Lawlor, DA and Morris, RW and James, AL and Jackson, CM and Hall, IP and Tobin, MD and SpiroMeta Consortium, (2011) Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med , 184 (7) 786 - 795. 10.1164/rccm.201102-0192OC. |
| Staines-Urias, E and Paez, MC and Doyle, P and Dudbridge, F and Serrano, NC and Ioannidis, JP and Keating, BJ and Hingorani, AD and Casas, JP (2012) Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis. Int J Epidemiol , 41 (6) 1764 - 1775. 10.1093/ije/dys162. |
| Sutaria, S and Philipson, P and Fitzpatrick, NK and Abrams, K and Moreno, SG and Timmis, A and Hingorani, AD and Hemingway, H (2012) Translational phases of evidence in a prognostic biomarker: a systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease. Heart , 98 (8) 615 - 622. 10.1136/heartjnl-2011-300862. |
| Talmud, PJ and Cooper, JA and Gaunt, T and Holmes, MV and Shah, S and Palmen, J and Drenos, F and Shah, T and Kumari, M and Kivimaki, M and Whittaker, J and Lawlor, DA and Day, IN and Hingorani, AD and Casas, JP and Humphries, SE (2011) Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies. DIABETOLOGIA , 54 (7) 1710 - 1719. 10.1007/s00125-011-2108-6. |
| Talmud, PJ and Cooper, JA and Palmen, J and Lovering, R and Drenos, F and Hingorani, AD and Humphries, SE (2008) Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men. CLIN CHEM , 54 (3) 467 - 474. 10.1373/clinchem.2007.095489. |
| Talmud, PJ and Drenos, F and Shah, S and Shah, T and Palmen, J and Verzilli, C and Gaunt, TR and Pallas, J and Lovering, R and Li, K and Casas, JP and Sofat, R and Kumari, M and Rodriguez, S and Johnson, T and Newhouse, SJ and Dominiczak, A and Samani, NJ and Caulfield, M and Sever, P and Stanton, A and Shields, DC and Padmanabhan, S and Melander, O and Hastie, C and Delles, C and Ebrahim, S and Marmot, MG and Smith, GD and Lawlor, DA and Munroe, PB and Day, IN and Kivimaki, M and Whittaker, J and Humphries, SE and Hingorani, AD and ASCOT Investigators, and NORDIL Investigators, and BRIGHT Consortium, (2009) Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip. AM J HUM GENET , 85 (5) 628 - 642. 10.1016/j.ajhg.2009.10.014. |
| Talmud, PJ and Hingorani, AD and Cooper, JA and Marmot, MG and Brunner, EJ and Kumari, M and Kivimaki, M and Humphries, SE (2010) Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study. BRIT MED J , 340 , Article b4838. 10.1136/bmj.b4838. |
| Talmud, PJ and Shah, S and Whittall, R and Futema, M and Howard, P and Cooper, JA and Harrison, SC and Li, K and Drenos, F and Karpe, F and Neil, HA and Descamps, OS and Langenberg, C and Lench, N and Kivimaki, M and Whittaker, J and Hingorani, AD and Kumari, M and Humphries, SE (2013) Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. Lancet , 381 (9874) 1293 - 1301. 10.1016/S0140-6736(12)62127-8. |
| Taylor, AE and Guthrie, PAI and Smith, GD and Golding, J and Sattar, N and Hingorani, AD and Deanfield, JE and Day, INM (2011) IQ, Educational Attainment, Memory and Plasma Lipids: Associations with Apolipoprotein E Genotype in 5995 Children. BIOL PSYCHIAT , 70 (2) 152 - 158. 10.1016/j.biopsych.2010.10.033. |
| Tonetti, M.S. and D'Aiuto, F. and Nibali, L. and Donald, A. and Storry, C. and Parkar, M. and Suvan, J. and Hingorani, A.D. and Vallance, P. and Deanfield, J. (2007) Treatment of periodontitis and endothelial function. New England Journal of Medicine , 356 (9) pp. 911-920. 10.1056/NEJMoa063186. | |
| Tonetti, MS and D'Aiuto, F and Nibali, L and Donald, A and Storry, C and Parkar, M and Suvan, J and Hingorani, AD and Vallance, P and Deanfield, J (2007) Treatment of periodontitis and endothelial function. NEW ENGL J MED , 356 (9) 911 - 920. |
| Tsakos, G and Sabbah, W and Hingorani, AD and Netuveli, G and Donos, N and Watt, RG and D'Aiuto, F (2010) Is periodontal inflammation associated with raised blood pressure? Evidence from a National US survey. J HYPERTENS , 28 (12) 2386 - 2393. 10.1097/HJH.0b013e32833e0fe1. |
| Ulrich, S and Hingorani, AD and Martin, J and Vallance, P (2000) What is the optimal age for starting lipid lowering treatment? A mathematical model. BRIT MED J , 320 (7242) 1134 - 1140. |
| Ulrich, S and Hingorani, AD and Martin, J and Vallance, P (2000) What is the optimal age for starting lipid lowering treatment? A mathematical model. BMJ , 320 (7242) 1134 - 1140. |
| Ulrich, S and Hingorani, AD and Martin, J and Vallance, P (1999) Lifetime risk of developing coronary heart disease. LANCET , 353 (9156) 925 - 925. |
| Vallance, P and Hingorani, AD and Ulrich, S (2000) Optimal age for starting lipid lowering treatment - Adjusted data do not justify a lower optimal age - Reply. BRIT MED J , 321 (7261) 638 - 638. |
| Verzilli, C and Shah, T and Casas, JP and Chapman, J and Sandhu, M and Debenham, SL and Boekholdt, MS and Khaw, KT and Wareham, NJ and Judson, R and Benjamin, EJ and Kathiresan, S and Larson, MG and Rong, J and Sofat, R and Humphries, SE and Smeeth, L and Cavalleri, G and Whittaker, JC and Hingorani, AD (2008) Bayesian meta-analysis of genetic association studies with different sets of markers. AM J HUM GENET , 82 (4) 859 - 872. 10.1016/j.ajhg.2008.01.016. |
| Welsh, P and Polisecki, E and Robertson, M and Jahn, S and Buckley, BM and de Craen, AJM and Ford, I and Jukema, JW and Macfarlane, PW and Packard, CJ and Stott, DJ and Westendorp, RGJ and Shepherd, J and Hingorani, AD and Smith, GD and Schaefer, E and Sattar, N (2010) Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach. J CLIN ENDOCR METAB , 95 (1) 93 - 99. 10.1210/jc.2009-1064. |
| Wensley, F and Gao, P and Burgess, S and Kaptoge, S and Di Angelantonio, E and Shah, T and Engert, JC and Clarke, R and Davey-Smith, G and Nordestgaard, BG and Saleheen, D and Samani, NJ and Sandhu, M and Anand, S and Pepys, MB and Smeeth, L and Whittaker, J and Casas, JP and Thompson, SG and Hingorani, AD and Danesh, J and Eiriksdottir, G and Harris, TB and Launer, LJ and Gudnason, V and Folsom, AR and Andrews, G and Ballantyne, CM and Samani, NJ and Hall, AS and Braund, PS and Balmforth, AJ and Whincup, PH and Morris, R and Lawlor, DA and Lowe, GDO and Timpson, N and Ebrahim, S and Ben-Shlomo, Y and Davey-Smith, G and Timpson, N and Nordestgaard, BG and Tybjaerg-Hansen, A and Zacho, J and Brown, M and Sandhu, M and Ricketts, SL and Ashford, S and Lange, L and Reiner, A and Cushman, M and Tracy, R and Wu, C and Ge, J and Zou, Y and Sun, A and Hung, J and McQuillan, B and Thompson, P and Beilby, J and Warrington, N and Palmer, LJ and Wanner, C and Drechsler, C and Hoffmann, MM and Fowkes, FGR and Lowe, GDO and Tzoulaki, I and Kumari, M and Miller, M and Marmot, M and Onland-Moret, C and van der Schouw, YT and Boer, JM and Wijmenga, C and Ricketts, L and Ashford, S and Sandhu, M and Khaw, KT and Vasan, RS and Schnabel, RB and Yamamoto, JF and Benjamin, EJ and Schunkert, H and Erdmann, J and Konig, IR and Hengstenberg, C and Chiodini, B and Franzosi, MG and Pietri, S and Gori, F and Rudock, M and Liu, Y and Lohman, K and Harris, TB and Humphries, SE and Hamsten, A and Norman, PE and Hankey, GJ and Jamrozik, K and Palmer, LJ and Rimm, EB and Pai, JK and Psaty, BM and Heckbert, SR and Bis, JC and Yusuf, S and Anand, S and Engert, JC and Xie, C and Collins, R and Clarke, R and Bennett, D and Kooner, J and Chambers, J and Elliott, P and Marz, W and Kleber, ME and Bohm, BO and Winkelmann, BR and Melander, O and Berglund, G and Koenig, W and Thorand, B and Baumert, J and Peters, A and Rimm, EB and Manson, J and Pai, JK and Humphries, SE and Cooper, JA and Talmud, PJ and Ladenvall, P and Johansson, L and Jansson, JH and Hallmans, G and Reilly, MP and Qu, L and Li, M and Rader, DJ and Watkins, H and Clarke, R and Hopewell, J and Saleheen, D and Danesh, J and Frossard, P and Sattar, N and Robertson, M and Shepherd, J and Schaefer, E and Hofman, A and Witteman, JCM and Kardys, I and Dehghan, A and de Faire, U and Bennet, A and Gigante, B and Leander, K and Ben-Shlomo, Y and Davey-Smith, G and Timpson, N and Peters, B and Maitland-van der Zee, AH and de Boer, A and Klungel, O and Reiner, A and Manson, J and Greenland, P and Dai, J and Liu, S and Kumari, M and Brunner, E and Kivimaki, M and Marmot, M and Sattar, N and O'Reilly, D and Ford, I and Packard, CJ and C Reactive Prot Coronary Heart Dis, and AGES, and ARIC, and BHF-FHS, and BRHS, and BWHHS, and CAPS, and CCHS CGPS CIHDS, and CHAOS, and CHS, and CRPHANS, and CUDAS CUPID, and 4D, and EAS, and ELSA, and EPICNL, and EPICNOR, and FRAMOFF, and GERMIFS, and GISSI-P, and HEALTHABC, and HIFMECH, and HIMS, and HPFS, and HVHS, and INTERHEART, and ISIS, and LOLIPOP, and LURIC, and MALMO, and MONICAKORA, and NHS, and NPHSII, and NSC, and PENNCATH, and PROCARDIS, and PROMIS, and PROSPER, and ROTTERDAM, and SHEEP, and SPEED, and UCP, and WHIOS, and WHITEII, and WOSCOPS, (2011) Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BRIT MED J , 342 , Article d548. 10.1136/bmj.d548. |
| Yiannakouris, N and Cooper, JA and Shah, S and Drenos, F and Ireland, HA and Stephens, JW and Li, KW and Elkeles, R and Godsland, IF and Kivimaki, M and Hingorani, AD and Kumari, M and Talmud, PJ and Humphries, SE (2012) IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk. Nutr Metab Cardiovasc Dis , 22 (12) 1024 - 1030. 10.1016/j.numecd.2011.05.009. |
| Yiannakouris, N and Cooper, JA and Shah, S and Ireland, H and Stephens, JW and Li, KW and Elkeles, R and Godsland, I and Kivimaki, M and Hingorani, AD and Talmud, PJ and Kumari, M and Humphries, SE (2010) Genetic variants near IRS1 and their association with type 2 diabetes, hyperinsulinemia and insulin resistance. DIABETES OBES METAB , 12 46 - 46. |
| Yu, CK and Casas, JP and Savvidou, MD and Sahemey, MK and Nicolaides, KH and Hingorani, AD (2006) Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis. BMC Pregnancy and Childbirth , 6 , Article 7. 10.1186/1471-2393-6-7. | |
| Zabaneh, D and Gaunt, TR and Kumari, M and Drenos, F and Shah, S and Berry, D and Power, C and Hypponen, E and Shah, T and Palmen, J and Pallas, J and Talmud, PJ and Casas, JP and Sofat, R and Lowe, G and Rumley, A and Morris, RW and Whincup, PH and Rodriguez, S and Ebrahim, S and Marmot, MG and Smith, GD and Lawlor, DA and Kivimaki, M and Whittaker, J and Hingorani, AD and Day, IN and Humphries, SE (2011) Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip. ANN HUM GENET , 75 456 - 467. 10.1111/j.1469-1809.2011.00654.x. |
| Zabaneh, D and Kumari, M and Sandhu, M and Wareham, N and Wainwright, N and Papamarkou, T and Hopewell, J and Clarke, R and Li, K and Palmen, J and Talmud, PJ and Kronenberg, F and Lamina, C and Summerer, M and Paulweber, B and Price, J and Fowkes, G and Stewart, M and Drenos, F and Shah, S and Shah, T and Casas, JP and Kivimaki, M and Whittaker, J and Hingorani, AD and Humphries, SE (2011) Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts. ATHEROSCLEROSIS , 217 (2) 447 - 451. 10.1016/j.atherosclerosis.2011.04.015. |
Proceedings paper
| Alves, JD and Clapp, BR and Stidwill, R and Chen, PP and Hingorani, AD and Singer, M and Isenberg, DA (2004) Human monoclonal IGG anticardiolipin antibodies induce nitric oxide synthase expression. In: THROMBOSIS RESEARCH. (pp. 615 - 615). PERGAMON-ELSEVIER SCIENCE LTD |
| Bautista, LE and Casas, JP and Smeeth, L and Hingorani, AD (2005) Estimation of bias in "Mendelian triangulation" studies. In: AMERICAN JOURNAL OF EPIDEMIOLOGY. (pp. S73 - S73). OXFORD UNIV PRESS INC |
| Brull, DJ and Serrano, N and Zito, F and Jones, L and Montgomery, HE and Rumley, A and Sharma, P and Lowe, GDO and World, MJ and Humphries, SE and Hingorani, AD (2003) A polymorphism in the human CRP gene influences basal and stimulated CRP levels: Implications for the prediction and pathogenesis of coronary heart disease. In: ATHEROSCLEROSIS. (pp. 198 - 198). ELSEVIER SCI IRELAND LTD |
| Brull, DJ and Serrano, N and Zito, F and Jones, L and Montgomery, HE and Rumley, A and Sharma, P and Lowe, GDO and World, MJ and Humphries, SE and Hingorani, AD (2003) A polymorphism in the human CRP gene influences basal and stimulated CRP levels: Implications for the prediction and pathogenesis of coronary heart disease. In: ATHEROSCLEROSIS. (pp. 192 - 192). ELSEVIER SCI IRELAND LTD |
| Casas, JP and Bautista, LE and Hingorani, AD and Sharma, P (2004) Plasma homocysteine, and ischaemic stroke: "Mendelian randomization" provides further evidence of causal link. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 1218 - 1218). B M J PUBLISHING GROUP |
| Clapp, B and Hirschfield, G and MacAllister, R and Gallimore, R and Vallance, P and Pepys, M and Hingorani, A (2003) C-reactive protein alters vascular reactivity by increasing nitric oxide production. In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. (pp. 319A - 319A). ELSEVIER SCIENCE INC |
| Holmes, MV and Shah, T and Vickery, C and Smeeth, L and Hingorani, AD and Casas, JP (2009) A FIELD SYNOPIS OF PHARMACOGENETIC STUDIES. In: ATHEROSCLEROSIS. (pp. E5 - E5). ELSEVIER IRELAND LTD |
| Langenberg, C and Jensen, AC and Barker, A and Brunner, EJ and Hingorani, AD and Kumari, M and Kivimaki, M and Wareham, NJ and Tabak, AG and Witte, DR (2010) Age-dependent genetic effects on post-load glucose during 18 years of follow-up of the Whitehall II Cohort. In: DIABETOLOGIA. (pp. S122 - S123). SPRINGER |
| Noori, M and Donald, A and Hingorani, A and Williams, DJ (2007) A prospective study of maternal endothelial function, angiogenic factors and placental function in women at risk of pre-eclampsia. In: Journal of Human Hypertension. (pp. 832 - 832). |
| Santhanakrishnan, VK and Berry, DJ and Hingorani, AD and Whittaker, JC and Jarvelin, MR and Hypponen, E (2011) Obesity is a Causal Risk Factor For Low Vitamin D Status: A Bi-Directional Mendelian Randomization Study on 40,000 Individuals. In: OBESITY. (pp. S231 - S231). NATURE PUBLISHING GROUP |
| Shah, S and Drenos, F and Shah, T and Palmen, J and Vezzili, C and Sofat, R and Kumari, M and Kivamaki, M and Pallas, J and MacFarlane, P and Whittaker, J and Talmud, PJ and Humphries, SE and Hingorani, AD (2009) IDENTIFICATION OF GENES ASSOCIATED WITH QT INTERVAL USING THE 50K CARDIO-METABOLIC SNP CHIP: RESULTS FROM THE WHITEHALL II STUDY. In: ATHEROSCLEROSIS. (pp. E11 - E11). ELSEVIER IRELAND LTD |
| Shah, T and Casas, J and Cooper, J and Hawe, E and Stephens, J and Hurel, S and Yudkin, J and Livingstone, S and Colhoun, H and Bautista, L and Meade, T and Gaffney, D and McMahon, A and Hamsten, A and Sattar, N and Humphries, SE and Hingorani, AD (2005) Mendelian randomisation and disease risk estimates for C-reactive protein (CRP). In: ATHEROSCLEROSIS. (pp. S4 - S5). ELSEVIER IRELAND LTD |
| Shah, T and Cooper, JA and Casas, JP and Pearce, K and Tinworth, L and Hingorani, AD and Miller, GJ and Humphries, SE (2006) CRP in the prediction and pathogenesis of cardiovascular events in middle-aged men; Results from the NPHSII study. In: ATHEROSCLEROSIS. (pp. S3 - S3). ELSEVIER IRELAND LTD |
| Shah, T and Newcombe, P and Addo, J and Casas, JP and Smeeth, L and Whittaker, J and Hingorani, AD (2009) CONSIDERATION OF ETHNICITY IN CORONARY RISK PREDICTION USING CRP. In: ATHEROSCLEROSIS. (pp. E11 - E11). ELSEVIER IRELAND LTD |
| Sharma, P and Whittaker, J and Casas, JP and Hingorani, AD and Ariyaratnam, R (2007) Genetics of ischaemic stroke in ethnic minorities. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 212 - 212). B M J PUBLISHING GROUP |
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