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Number of items: 228.

Article

(2001) The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function Leeson CP,. Circulation , 102 (18) 1366 - ?.

Alves, JD; Clapp, BR; Stidwill, R; Chen, PP; Hingorani, AD; Singer, M; Isenberg, DA; (2006) Human monoclonal IgG anticardiolipin antibodies induce nitric oxide synthase expression. ATHEROSCLEROSIS , 185 (2) 246 - 253. 10.1016/j.atherosclerosis.2005.06.044.

Angelakopoulou, A; Shah, T; Sofat, R; Shah, S; Berry, DJ; Cooper, J; ... Hingorani, AD; + view all (2012) Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. European Heart Journal , 33 (3) 393 - 407. 10.1093/eurheartj/ehr225. Green and gold open access
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Ariyaratnam, R; Casas, JP; Whittaker, J; Smeeth, L; Hingorani, AD; Sharma, P; (2007) Genetics of ischaemic stroke among persons of non-European descent: A meta-analysis of eight genes involving; 32,500 individuals. PLOS MED , 4 (4) , Article e131. 10.1371/journal.pmed.0040131. Gold open access

Artigas, MS; Loth, DW; Wain, LV; Gharib, SA; Obeidat, M; Tang, WB; ... GIANT Consortium,; + view all (2011) Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. NAT GENET , 43 (11) 1082 - U70. 10.1038/ng.941.

Artigas, MS; Wain, LV; Repapi, E; Obeidat, M; Sayers, I; Burton, PR; ... SpiroMeta Consortium,; + view all (2011) Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function. AM J RESP CRIT CARE , 184 (7) 786 - 795. 10.1164/rccm.201102-0192OC.

Asselbergs, FW; Guo, Y; van Iperen, EP; Sivapalaratnam, S; Tragante, V; Lanktree, MB; ... Drenos, F; + view all (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet , 91 (5) 823 - 838. 10.1016/j.ajhg.2012.08.032.

Bautista, LE; Smeeth, L; Hingorani, AD; Casas, JP; (2006) Estimation of bias in nongenetic observational studies using "Mendelian triangulation". ANN EPIDEMIOL , 16 (9) 675 - 680. 10.1016/j.annepidem.2006.02.001.

Bellamy, L; Casas, JP; Hingorani, AD; Williams, D; (2009) Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. LANCET , 373 (9677) 1773 - 1779.

Bellamy, L; Casas, JP; Hingorani, AD; Williams, DJ; (2007) Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BRIT MED J , 335 (7627) 974 - 977. 10.1136/bmj.39335.85301.BE.

Bellamy, L; Casas, JP; Hingorani, AD; Williams, DJ; (2007) Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ , 335 (7627) 974 - ?. 10.1136/bmj.39335.385301.BE.

Berry, DJ; Vimaleswaran, KS; Whittaker, JC; Hingorani, AD; Hyppönen, E; (2012) Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D. PLoS One , 7 (5) , Article e37465 . 10.1371/journal.pone.0037465. Green and gold open access
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Bessant, R; Hingorani, A; Patel, L; MacGregor, A; Isenberg, DA; Rahman, A; (2004) Risk of coronary heart disease and stroke in a large British cohort of patients with systemic lupus erythematosus. RHEUMATOLOGY , 43 (7) 924 - 929. 10.1093/rheumatology/keh213.

Bhagat, K; Hingorani, A; Vallance, P; (1997) Flow associated or flow mediated dilatation? More than just semantics. Heart , 78 (1) 7 - 8.

Bhagat, K; Hingorani, AD; Palacios, M; Charles, IG; Vallance, P; (1999) Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS. CARDIOVASC RES , 41 (3) 754 - 764.

Bodalia, PN; Grosso, AM; Sofat, R; Macallister, RJ; Smeeth, L; Dhillon, S; ... Hingorani, AD; + view all (2013) Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials. Br J Clin Pharmacol , 76 (5) 649 - 667. 10.1111/bcp.12083.

Brull, DJ; Serrano, N; Zito, F; Jones, L; Montgomery, HE; Rumley, A; ... Hingorani, AD; + view all (2003) Human CRP gene polymorphism influences CRP levels - Implications for the prediction and pathogenesis of coronary heart disease. ARTERIOSCL THROM VAS , 23 (11) 2063 - 2069. 10.1161/01.ATV.0000084640.21712.9C.

Brunner, EJ; Kivimaki, M; Witte, DR; Lawlor, DA; Smith, GD; Cooper, JA; ... Kumari, M; + view all (2008) Inflammation, insulin resistance, and diabetes-mendelian randomization using CRP haplotypes points upstream. PLOS MED , 5 (8) , Article e155. 10.1371/journal.pmed.0050155. Gold open access

Casas, JP; Bautista, LE; Humphries, SE; Hingorani, AD; (2004) Endothelial nitric oxide synthase genotype and ischemic heart disease - Meta-analysis of 26 studies involving 23028 subjects. CIRCULATION , 109 (11) 1359 - 1365. 10.1161/01.CIR.0000121357.76910.A3.

Casas, JP; Bautista, LE; Smeeth, L; Sharma, P; Hingorani, AD; (2005) Homocysteine and stroke: evidence on a causal link from mendelian randomisation. LANCET , 365 (9455) 224 - 232.

Casas, JP; Cavalleri, GL; Bautista, LE; Smeeth, L; Humphries, SE; Hingorani, AD; (2006) Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: A HuGE review. AM J EPIDEMIOL , 164 (10) 921 - 935. 10.1093/aje/kwj302.

Casas, JP; Chua, WL; Loukogeorgakis, S; Vallance, P; Smeeth, L; Hingorani, AD; MacAllister, RJ; (2005) Effect of inhibitors of the renin-angiotensin system and other anti hypertensive drugs on renal outcomes: systematic review and meta-analysis. LANCET , 366 (9502) 2026 - 2033.

Casas, JP; Cooper, J; Miller, GJ; Hingorani, AD; Humphries, SE; (2006) Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies. ANN HUM GENET , 70 145 - 169. 10.1111/j.1469-1809.2005.00241.x.

Casas, JP; Hingorani, AD; (2012) The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet , 379 (9822) 1214 - 1224. 10.1016/S0140-6736(12)60110-X. Green and gold open access
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Casas, JP; Hingorani, AD; Bautista, LE; Sharma, P; (2004) Meta-analysis of genetic studies in ischemic stroke - Thirty-two genes involving approximately 18 000 cases and 58 000 controls. ARCH NEUROL-CHICAGO , 61 (11) 1652 - 1661.

Casas, JP; Hingorani, AD; Humphries, SE; Smeeth, L; Bautista, LE; (2004) Do meta-analyses of association studies of endothelial nitric oxide synthase variants and ischemic heart disease provide conclusive answers? Response. CIRCULATION , 110 (11) E305 - E306.

Casas, JP; Hingorani, AD; MacAllister, RJ; Smeeth, L; (2006) Progression of renal disease - can we forget about inhibition of the renin-angiotensin system? Authors' reply. NEPHROL DIAL TRANSPL , 21 (9) 2352 - 2353. 10.1093/ndt/gfl316.

Casas, JP; Ninio, E; Panayiotou, A; Palmen, J; Cooper, JA; Ricketts, SL; ... Talmud, PJ; + view all (2010) PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A2 Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry (vol 121, pg 2284, 2010). CIRCULATION , 122 (3) E400 - E400. 10.1161/CIR.0b013e3181eb187c.

Casas, JP; Ninio, E; Panayiotou, A; Palmen, J; Cooper, JA; Ricketts, SL; ... Talmud, PJ; + view all (2010) PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A(2) Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry. CIRCULATION , 121 (21) 2284 - U74. 10.1161/CIRCULATIONAHA.109.923383.

Casas, JP; Shah, T; Cooper, J; Hawe, E; McMahon, AD; Gaffney, D; ... Hingorani, AD; + view all (2006) Insight into the nature of the CRP-coronary event association using Mendelian randomization. INT J EPIDEMIOL , 35 (4) 922 - 931. 10.1093/ije/dyl041.

Casas, JP; Shah, T; Hingorani, AD; Danesh, J; Pepys, MB; (2008) C-reactive protein and coronary heart disease: a critical review. J INTERN MED , 264 (4) 295 - 314. 10.1111/j.1365-2796.2008.02015.x.

Casas, JP; Vallance, P; Smeeth, L; Hingorani, AD; MacAllister, RJ; (2006) Renoprotective effects of renin-angiotensin-system inhibitors - Reply. LANCET , 367 (9514) 900 - 902.

Chakravarthy, U; McKay, GJ; de Jong, PT; Rahu, M; Seland, J; Soubrane, G; ... Fletcher, AE; + view all (2013) ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study. Ophthalmology , 120 (2) 342 - 348. 10.1016/j.ophtha.2012.08.004.

Chan, NN; MacAllister, RJ; Colhoun, HM; Vallance, P; Hingorani, AD; (2001) Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. J CLIN ENDOCR METAB , 86 (6) 2499 - 2504.

Chan, NN; Vallance, P; Colhoun, HM; MacAllister, RJ; Hingorani, AD; Conway, GS; (2002) The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome. CLIN ENDOCRINOL , 56 (5) 615 - 620.

Chan, NN; Vallance, PJ; Macallister, RJ; Hingorani, AD; Colhoun, HM; (2000) Impaired nitric oxide response in resistance vessels in human type 1 diabetes in vivo. CIRCULATION , 102 (18) 326 - 326.

Chen, Z; Ahluwalia, A; Selwood, DL; Vallance, P; Hingorani, AD; (1999) Enhancement of endothelium-dependent vasodilatation by oestradiol 17-beta: Role of the pterin pathway. BRIT J PHARMACOL , 126 U32 - U32.

Clapp, BR; Hingorani, AD; Kharbanda, RK; Mohamed-Ali, V; Stephens, JW; Vallance, P; MacAllister, RJ; (2004) Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. CARDIOVASC RES , 64 (1) 172 - 178. 10.1016/j.cardiores.2004.06.020.

Clapp, BR; Hirschfield, GM; Storry, C; Gallimore, JR; Stidwill, RP; Singer, M; ... Hingorani, AD; + view all (2005) Inflammation and endothelial function - Direct vascular effects of human C-reactive protein on nitric oxide bioavailability. CIRCULATION , 111 (12) 1530 - 1536. 10.1161/01.CIR.0000159336.31613.31.

Clarke, R; Emberson, JR; Breeze, E; Casas, JP; Parish, S; Hingorani, AD; ... Smeeth, L; + view all (2008) Biomarkers of inflammation predict both vascular and non-vascular mortality in older men. EUR HEART J , 29 (6) 800 - 809. 10.1093/eurheartj/ehn049.

Costelloe, SJ; El-Sayed Moustafa, JS; Drenos, F; Palmen, J; Li, Q; Whiting, S; ... Talmud, PJ; + view all (2012) Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits. Circ Cardiovasc Genet , 5 (5) 555 - 560. 10.1161/CIRCGENETICS.111.961037.

D'Aiuto, F; Casas, JP; Shah, T; Humphries, SE; Hingorani, AD; Tonetti, MS; (2005) C-reactive protein (+1444C > T) polymorphism influences CRP response following a moderate inflammatory stimulus. ATHEROSCLEROSIS , 179 (2) 413 - 417. 10.1016/j.atherosclerosis.2004.10.036.

D'Aiuto, F; Sabbah, W; Netuveli, G; Donos, N; Hingorani, AD; Deanfield, J; Tsakos, G; (2008) Association of the metabolic syndrome with severe periodontitis in a large US population-based survey. J CLIN ENDOCR METAB , 93 (10) 3989 - 3994. 10.1210/jc.2007-2522.

Dastani, Z; Hivert, MF; Timpson, N; Perry, JR; Yuan, X; Scott, RA; ... Kathiresan, S; + view all (2012) Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genetics , 8 (3) , Article e1002607 . 10.1371/journal.pgen.1002607. Green and gold open access
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D’Aiuto, F.; Casas, J.P.; Shah, T.; Humphries, S.E.; Hingorani, A.D.; Tonetti, M.S.; (2005) C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus. Atherosclerosis , 179 (2) pp. 413-417. 10.1016/j.atherosclerosis.2004.10.036.

den Hoed, M; Luan, J; Langenberg, C; Cooper, C; Sayer, AA; Jameson, K; ... Loos, RJ; + view all (2013) Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples. Int J Obes (Lond) , 37 (2) 191 - 196. 10.1038/ijo.2012.34.

Denaxas, SC; George, J; Herrett, E; Shah, AD; Kalra, D; Hingorani, AD; ... Hemingway, H; + view all (2012) Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER). Int J Epidemiol , 41 (6) 1625 - 1638. 10.1093/ije/dys188. Gold open access

Dickerson, JEC; Hingorani, AD; Ashby, MJ; Palmer, CR; Brown, MJ; (1999) Optimisation of antihypertensive treatment by crossover rotation of four major classes. LANCET , 353 (9169) 2008 - 2013.

Donald, AE; Charakida, M; Falaschetti, E; Lawlor, DA; Halcox, JP; Golding, J; ... Deanfield, JE; + view all (2010) Determinants of vascular phenotype in a large childhood population: the Avon Longitudinal Study of Parents and Children (ALSPAC). EUR HEART J , 31 (12) 1502 - 1510. 10.1093/eurheartj/ehq062.

Douglas, IJ; Evans, SJ; Hingorani, AD; Grosso, AM; Timmis, A; Hemingway, H; Smeeth, L; (2012) Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs. BMJ , 345 e4388 - ?.

Drenos, F; Talmud, PJ; Casas, JP; Smeeth, L; Palmen, J; Humphries, SE; Hingorani, AD; (2009) Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. HUM MOL GENET , 18 (12) 2305 - 2316. 10.1093/hmg/ddp159.

Dupuis, J; Langenberg, C; Prokopenko, I; Saxena, R; Soranzo, N; Jackson, AU; ... MAGIC Investigators,; + view all (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. NAT GENET , 42 (2) 105 - U32. 10.1038/ng.520.

Dupuis, J; Langenberg, C; Prokopenko, I; Saxena, R; Soranzo, N; Jackson, AU; ... Ines Barroso MAGIC Investigators,; + view all (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010). NAT GENET , 42 (5) 464 - 464. 10.1038/ng0510-464a.

Ehret, GB; Munroe, PB; Rice, KM; Bochud, M; Johnson, AD; Chasman, DI; ... CHARGE-HF Consortium,; + view all (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. NATURE , 478 (7367) 103 - 109. 10.1038/nature10405.

Falaschetti, E; Hingorani, AD; Jones, A; Charakida, M; Finer, N; Whincup, P; ... Deanfield, JE; + view all (2010) Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children. EUR HEART J , 31 (24) 3063 - 3072. 10.1093/eurheartj/ehq355.

Fox, ER; Young, JH; Li, Y; Dreisbach, AW; Keating, BJ; Musani, SK; ... Levy, D; + view all (2011) Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet , 20 (11) 2273 - 2284. 10.1093/hmg/ddr092.

Freathy, RM; Kazeem, GR; Morris, RW; Johnson, PC; Paternoster, L; Ebrahim, S; ... Munafò, M; + view all (2011) Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. Int J Epidemiol , 40 (6) 1617 - 1628. 10.1093/ije/dyr077.

Gaunt, TR; Shah, S; Nelson, CP; Drenos, F; Braund, PS; Adeniran, I; ... Day, IN; + view all (2012) Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip. Circ Cardiovasc Genet , 5 (6) 630 - 638. 10.1161/CIRCGENETICS.112.962852.

Gertow, K; Sennblad, B; Strawbridge, RJ; Ohrvik, J; Zabaneh, D; Shah, S; ... Hamsten, A; + view all (2012) Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. Circ Cardiovasc Genet , 5 (6) 656 - 665. 10.1161/CIRCGENETICS.112.963660.

Giambartolomei, C; Vukcevic, D; Schadt, EE; Hingorani, AD; Wallace, C; Plagnol, V; (2013) Bayesian test for co-localisation between pairs of genetic association studies using summary statistics.

Grosso, A; Douglas, I; Hingorani, A; MacAllister, R; Smeeth, L; (2008) Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions. BRIT J CLIN PHARMACO , 66 (5) 689 - 694. 10.1111/j.1365-2125.2008.03273.x. Gold open access

Grosso, A; Douglas, I; Hingorani, AD; MacAllister, R; Hubbard, R; Smeeth, L; (2009) Inhaled tiotropium bromide and risk of stroke. BRIT J CLIN PHARMACO , 68 (5) 731 - 736. 10.1111/j.1365-2125.2009.03517.x.

Grosso, A; Douglas, I; MacAllister, R; Petersen, I; Smeeth, L; Hingorani, AD; (2011) Use of the self-controlled case series method in drug safety assessment. EXPERT OPIN DRUG SAF , 10 (3) 337 - 340. 10.1517/14740338.2011.562187.

Grosso, AM; Bodalia, PN; MacAllister, RJ; Hingorani, AD; Moon, JC; Scott, MA; (2011) Cost-saving opportunities and angiotensin-II receptor blocker prescribing. INT J CLIN PRACT , 65 (8) 912 - 912. 10.1111/j.1742-1241.2011.02730.x.

Grosso, AM; Bodalia, PN; MacAllister, RJ; Hingorani, AD; Moon, JC; Scott, MA; (2011) Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis. INT J CLIN PRACT , 65 (3) 253 - 263. 10.1111/j.1742-1241.2011.02633.x.

Harrison, SC; Smith, AJ; Jones, GT; Swerdlow, DI; Rampuri, R; Bown, MJ; ... Humphries, SE; + view all (2013) Interleukin-6 receptor pathways in abdominal aortic aneurysm. European Heart Journal , 34 (48) , Article ehs354v1. 10.1093/eurheartj/ehs354. Green open access
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Harrison, SC; Zabaneh, D; Asselbergs, FW; Drenos, F; Jones, GT; Shah, S; ... Humphries, SE; + view all (2013) A gene-centric study of common carotid artery remodelling. Atherosclerosis , 226 (2) 440 - 446. 10.1016/j.atherosclerosis.2012.11.002.

Healy, DG; Abou-Sleiman, PM; Lees, AJ; Casas, JP; Quinn, N; Bhatia, K; ... Wood, NW; + view all (2004) Tau gene and Parkinson's disease: a case-control study and meta-analysis. J NEUROL NEUROSUR PS , 75 (7) 962 - 965. 10.1136/jnnp.2003.026203.

Hemingway, H; Philipson, P; Chen, RL; Fitzpatrick, NK; Damant, J; Shipley, M; ... Hingorani, AD; + view all (2010) Evaluating the Quality of Research into a Single Prognostic Biomarker: A Systematic Review and Meta-analysis of 83 Studies of C-Reactive Protein in Stable Coronary Artery Disease. PLOS MED , 7 (6) , Article e1000286. 10.1371/journal.pmed.1000286. Gold open access

Henriksson, M; Palmer, S; Chen, RL; Damant, J; Fitzpatrick, NK; Abrams, K; ... Hemingway, H; + view all (2010) Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery. BRIT MED J , 340 , Article b5606. 10.1136/bmj.b5606.

Hingorani, A; (2004) Resolving inconsistency in the results of genetic association studies of cardiovascular disease. Clinical Science , 107 (3) 251 - 253.

Hingorani, AD; (2004) Diet, the endothelium and atherosclerosis. CLIN SCI , 106 (5) 447 - 448. 10.1042/CS20040023.

Hingorani, AD; (2003) Endothelial nitric oxide synthase polymorphisms and hypertension. CURR HYPERTENS REP , 5 (1) 19 - 25.

Hingorani, AD; (2001) Polymorphisms in endothelial nitric oxide synthase and atherogenesis - John French Lecture 2000. ATHEROSCLEROSIS , 154 (3) 521 - 527.

HINGORANI, AD; (1993) THE FLOSEQUINAN EXPERIENCE AND ITS IMPLICATIONS. BRIT J HOSP MED , 50 (11) 683 - 683.

Hingorani, AD; (1992) Postinfectious myocarditis. BMJ , 304 (6843) 1676 - 1678.

Hingorani, AD; Bhagat, K; Palacios, M; Griffin, GE; MacAllister, RJ; Vallance, P; (1999) Acute systemic inflammation impairs endothelium-dependent dilatation in humans. BRIT J PHARMACOL , 126 U31 - U31.

HINGORANI, AD; BLOOMBERG, TJ; (1995) ULTRASOUND-GUIDED PIGTAIL CATHETER DRAINAGE OF MALIGNANT PERICARDIAL-EFFUSIONS. CLIN RADIOL , 50 (1) 15 - 19.

Hingorani, AD; Brown, MJ; (1996) Identifying the genes for human hypertension. NEPHROL DIAL TRANSPL , 11 (4) 575 - 586.

Hingorani, AD; Brown, MJ; (1996) A simple molecular assay for the C-1166 variant of the angiotensin II type 1 receptor gene (vol 213, pg 725, 1995). BIOCHEM BIOPH RES CO , 218 (1) 420 - 420.

HINGORANI, AD; BROWN, MJ; (1995) A SIMPLE MOLECULAR ASSAY FOR THE C-1166 VARIANT OF THE ANGIOTENSIN-II TYPE-1 RECEPTOR GENE. BIOCHEM BIOPH RES CO , 213 (2) 725 - 729.

Hingorani, AD; Chan, NN; (2001) D-lactate encephalopathy. LANCET , 358 (9295) 1814 - 1814.

Hingorani, AD; Cross, J; Kharbanda, RK; Mullen, MJ; Bhagat, K; Taylor, M; ... Vallance, P; + view all (2000) Acute systemic inflammation impairs endothelium-dependent dilatation in humans. CIRCULATION , 102 (9) 994 - 999.

Hingorani, AD; Cross, JM; Kharbanda, RK; Mullen, MJ; Bhagat, K; Taylor, M; ... Vallance, P; + view all (1999) Acute systemic inflammation impairs endothelium-dependent dilation in humans. CIRCULATION , 100 (18) 48 - 48.

Hingorani, AD; D'Aiuto, F; (2008) Chronic inflammation, periodontitis and cardiovascular diseases. ORAL DIS , 14 (2) 102 - 104. 10.1111/j.1601-0825.2007.01439.x.

HINGORANI, AD; DOLLERY, CT; OAKLEY, CM; BLOOM, SR; COHEN, J; (1992) HAMMERSMITH STAFF ROUNDS - POSTINFECTIOUS MYOCARDITIS. BRIT MED J , 304 (6843) 1676 - 1678.

HINGORANI, AD; FOLEY, TH; (1995) NONSUSTAINED BROAD-COMPLEX TACHYCARDIA FOLLOWING INTRAVENOUS ADENOSINE. J ACCID EMERG MED , 12 (3) 208 - 209.

Hingorani, AD; Hemingway, H; (2011) How should we balance individual and population benefits of statins for preventing cardiovascular disease? BRIT MED J , 342 , Article c6244. 10.1136/bmj.c6244.

Hingorani, AD; Jia, HY; Stevens, PA; Hopper, R; Dickerson, JEC; Brown, MJ; (1995) Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition. JOURNAL OF HYPERTENSION , 13 (12) 1602 - 1609.

HINGORANI, AD; JONES, AT; DZIERSK, J; GOLDINGWOOD, D; LEIGH, JM; (1994) ADULT EPIGLOTTITIS - ESTABLISH AN AIRWAY EARLY. BRIT MED J , 308 (6930) 719 - 719.

Hingorani, AD; Liang, CF; Fatibene, J; Lyon, A; Monteith, S; Parsons, A; ... Brown, MJ; + view all (1999) A common variant of the endothelial nitric oxide synthase (Glu(298)-> Asp) is a major risk factor for coronary artery disease in the UK. CIRCULATION , 100 (14) 1515 - 1520.

Hingorani, AD; Liang, CF; Fatibene, J; Parsons, A; Hopper, RV; Trutwein, D; ... Brown, MJ; + view all (1997) A common variant of the endothelial nitric oxide synthase gene is a risk factor for coronary atherosclerosis in the east Anglian region of the UK. CIRCULATION , 96 (8) 3050 - 3050.

HINGORANI, AD; MACDOUGALL, IC; BROWNE, M; WALKER, RWH; TOMSON, CRV; (1993) SUCCESSFUL TREATMENT OF ACUTE D-LACTATE ENCEPHALOPATHY BY HEMODIALYSIS. NEPHROL DIAL TRANSPL , 8 (11) 1283 - 1285.

Hingorani, AD; OHanlon, S; Halloran, SP; Wright, JP; Foley, TH; (1997) Evaluation of a paired creatine kinase test for the diagnosis of acute myocardial infarction in patients with a non-diagnostic electrocardiogram. J ACCID EMERG MED , 14 (3) 134 - 138.

Hingorani, AD; Psaty, BM; (2010) Modeling Cardiovascular Disease Prevention Reply. JAMA-J AM MED ASSOC , 303 (9) 835 - 835.

Hingorani, AD; Psaty, BM; (2009) Primary Prevention of Cardiovascular Disease Time to Get More or Less Personal? JAMA-J AM MED ASSOC , 302 (19) 2144 - 2145.

Hingorani, AD; Shah, T; Casas, JP; (2006) Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk. EUR HEART J , 27 (11) 1261 - 1263. 10.1193/eurheart/ehl852.

Hingorani, AD; Shah, T; Casas, JP; (2006) Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk. Eur Heart J , 27 (11) 1261 - 1263. 10.1093/eurheartj/ehi852.

Hingorani, AD; Shah, T; Casas, JP; Humphries, SE; Talmud, PJ; (2009) C-Reactive Protein and Coronary Heart Disease: Predictive Test or Therapeutic Target? CLIN CHEM , 55 (2) 239 - 255. 10.1373/clinchem.2008.115923.

Hingorani, AD; Shah, T; Kumari, M; Sofat, R; Smeeth, L; (2010) Science, medicine, and the future Translating genomics into improved healthcare. BRIT MED J , 341 , Article c5945. 10.1136/bmj.c5945.

Hingorani, AD; Shah, T; Kumari, M; Sofat, R; Smeeth, L; (2010) Translating genomics into improved healthcare. BMJ , 341 c5945 - ?.

Hingorani, AD; Sharma, P; Jia, HY; Hopper, R; Brown, MJ; (1996) Blood pressure and the M235T polymorphism of the angiotensinogen gene. HYPERTENSION , 28 (5) 907 - 911.

Hingorani, AD; Sofat, R; Morris, RW; Whincup, P; Lowe, GD; Mindell, J; ... Shah, T; + view all (2012) Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease? Eur Heart J , 33 (18) 2258 - 2264. 10.1093/eurheartj/ehs168.

Hingorani, AD; Vallance, P; (1999) Hypothesis of program is flawed - Reply. BRIT MED J , 318 (7195) 1419 - 1419.

Hingorani, AD; Vallance, P; (1999) A simple computer program for guiding management of cardiovascular risk factors and prescribing. BRIT MED J , 318 (7176) 101 - 105.

HINGORANI, AD; WAINSWORTH, RW; (1993) PULMONARY MICROEMBOLIZATION AND TEMAZEPAM. BRIT MED J , 307 (6904) 623 - 624.

Hingorani, AD; Windt, DA; Riley, RD; Abrams, K; Moons, KG; Steyerberg, EW; ... PROGRESS Group,; + view all (2013) Prognosis research strategy (PROGRESS) 4: stratified medicine research. BMJ , 346 e5793 - ?. Gold open access

Holmes, MV; Asselbergs, FW; Palmer, TM; Drenos, F; Lanktree, MB; Nelson, CP; ... Casas, JP; + view all (2014) Mendelian randomization of blood lipids for coronary heart disease. Eur Heart J 10.1093/eurheartj/eht571.

Holmes, MV; Casas, JP; Hingorani, AD; (2011) Putting genomics into practice. BRIT MED J , 343 , Article d4953. 10.1136/bmj.d4953.

Holmes, MV; Exeter, HJ; Folkersen, L; Nelson, CP; Guardiola, M; Cooper, JA; ... Talmud, PJ; + view all (2014) A Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA2)-V Isoenzyme in Coronary Heart Disease: A Modified Mendelian Randomization Analysis Using PLA2G5 Expression Levels. Circ Cardiovasc Genet 10.1161/CIRCGENETICS.113.000271.

Holmes, MV; Harrison, S; Talmud, PJ; Hingorani, AD; Humphries, SE; (2011) Utility of genetic determinants of lipids and cardiovascular events in assessing risk. NAT REV CARDIOL , 8 (4) 207 - 221. 10.1038/nrcardio.2011.6.

Holmes, MV; Hingorani, AD; Casas, JP; (2012) CYP2C19 Genotype and Cardiovascular Events Reply. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION , 307 (14) 1484 - 1485.

Holmes, MV; Lange, LA; Palmer, T; Lanktree, MB; North, KE; Almoguera, B; ... Keating, BJ; + view all (2014) Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis. Am J Hum Genet 10.1016/j.ajhg.2013.12.014.

Holmes, MV; Newcombe, P; Hubacek, JA; Sofat, R; Ricketts, SL; Cooper, J; ... Casas, JP; + view all (2011) Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. LANCET , 378 (9791) 584 - 594. 10.1016/S0140-6736(11)60872-6. Gold open access

Holmes, MV; Perel, P; Shah, T; Hingorani, AD; Casas, JP; (2011) CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis. JAMA , 306 (24) 2704 - 2714. 10.1001/jama.2011.1880.

Holmes, MV; Shah, T; Vickery, C; Smeeth, L; Hingorani, AD; Casas, JP; (2009) Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies. PLOS ONE , 4 (12) , Article e7960. 10.1371/journal.pone.0007960. Green and gold open access
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Holmes, MV; Simon, T; Exeter, HJ; Folkersen, L; Asselbergs, FW; Guardiola, M; ... Talmud, PJ; + view all (2013) Secretory Phospholipase A2-IIA and Cardiovascular Disease: a Mendelian randomization study. J Am Coll Cardiol 10.1016/j.jacc.2013.06.044.

Howe, LD; Galobardes, B; Sattar, N; Hingorani, AD; Deanfield, J; Ness, AR; ... Lawlor, DA; + view all (2010) Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study. INT J OBESITY , 34 (7) 1149 - 1159. 10.1038/ijo.2010.52.

Hu, Y; Li, L; Ehm, MG; Bing, N; Song, K; Nelson, MR; ... Kang, HM; + view all (2013) The benefits of using genetic information to design prevention trials. Am J Hum Genet , 92 (4) 547 - 557. 10.1016/j.ajhg.2013.03.003.

Humphries, SE; Hingorani, A; (2006) Pharmacogenetics: Progress, pitfalls and clinical potential for coronary heart disease. VASC PHARMACOL , 44 (2) 119 - 125. 10.1016/j.vph.2005.10.003.

International Consortium for Blood Pressure Genome-Wide Association Studies,; Ehret, GB; Munroe, PB; Rice, KM; Bochud, M; Johnson, AD; ... Johnson, T; + view all (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature , 478 (7367) 103 - 109. 10.1038/nature10405.

Jeerooburkhan, N; Jones, LC; Bujac, S; Cooper, JA; Miller, GJ; Vallance, P; ... Hingorani, AD; + view all (2001) Genetic and environmental determinants of plasma nitrogen oxides and risk of ischemic heart disease. HYPERTENSION , 38 (5) 1054 - 1061.

Jensen, AC; Barker, A; Kumari, M; Brunner, EJ; Kivimaki, M; Hingorani, AD; ... Langenberg, C; + view all (2011) Associations of Common Genetic Variants With Age-Related Changes in Fasting and Postload Glucose Evidence From 18 Years of Follow-Up of the Whitehall II Cohort. DIABETES , 60 (5) 1617 - 1623. 10.2337/db10-1393.

Jia, HY; Hingorani, AD; Sharma, P; Hopper, R; Dickerson, C; Trutwein, D; ... Brown, MJ; + view all (1999) Association of the G(s)alpha gene with essential hypertension and response to beta-blockade. HYPERTENSION , 34 (1) 8 - 14.

Johnson, T; Gaunt, TR; Newhouse, SJ; Padmanabhan, S; Tomaszewski, M; Kumari, M; ... Munroe, PB; + view all (2011) Blood pressure loci identified with a gene-centric array. Am J Hum Genet , 89 (6) 688 - 700. 10.1016/j.ajhg.2011.10.013.

Jones, A; Charakida, M; Falaschetti, E; Hingorani, AD; Finer, N; Masi, S; ... Deanfield, JE; + view all (2012) Adipose and height growth through childhood and blood pressure status in a large prospective cohort study. Hypertension , 59 (5) 919 - 925. 10.1161/HYPERTENSIONAHA.111.187716. Gold open access

Jones, LC; Hingorani, AD; (2005) Genetic regulation of endothelial function. HEART , 91 (10) 1275 - 1277. 10.1136/hrt.2005.061325.

Jones, LC; Tran, CTL; Leiper, JM; Hingorani, AD; Vallance, P; (2003) Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells. BIOCHEM BIOPH RES CO , 310 (3) 836 - 843. 10.1016/j.bbrc.2003.09.097.

Ken-Dror, G; Drenos, F; Humphries, SE; Talmud, PJ; Hingorani, AD; Kivimaki, M; ... Ireland, HA; + view all (2010) Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men. J THROMB HAEMOST , 8 (11) 2394 - 2403. 10.1111/j.1538-7836.2010.04035.x.

Khan, TA; Shah, T; Prieto, D; Zhang, W; Price, J; Fowkes, GR; ... Casas, JP; + view all (2013) Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. Int J Epidemiol , 42 (2) 475 - 492. 10.1093/ije/dyt034.

Kharbanda, RK; Walton, B; Allen, M; Klein, N; Hingorani, AD; MacAllister, RJ; Vallance, P; (2002) Prevention of inflammation-induced endothelial dysfunction - A novel vasculo-protective action of aspirin. CIRCULATION , 105 (22) 2600 - 2604. 10.1161/01.CIR.0000017863.52347.6C.

Kivimaki, M; Lawlor, DA; Smith, GD; Kumari, M; Donald, A; Britton, A; ... Hingorani, AD; + view all (2008) Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study. PLOS ONE , 3 (8) , Article e3013. 10.1371/journal.pone.0003013. Green and gold open access
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Kuper, H; Nicholson, A; Kivimaki, M; Aitsi-Selmi, A; Cavalleri, G; Deanfield, JE; ... Hemingway, H; + view all (2009) Evaluating the causal relevance of diverse risk markers: horizontal systematic review. BRIT MED J , 339 , Article b4265. 10.1136/bmj.b4265.

Lanktree, MB; Guo, YR; Murtaza, M; Glessner, JT; Bailey, SD; Onland-Moret, NC; ... WHII 50K Grp,; + view all (2011) Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. AM J HUM GENET , 88 (1) 6 - 18. 10.1016/j.ajhg.2010.11.007.

Leeson, CP; Hingorani, AD; Mullen, MJ; Jeerooburkhan, N; Kattenhorn, M; Muller, DP; ... Deanfield, JE; + view all (2000) The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. CIRCULATION , 102 (18) 279 - 279.

Leeson, CPM; Hingorani, AD; Mullen, MJ; Jeerooburkhan, N; Kattenhorn, M; Cole, TJ; ... Deanfield, JE; + view all (2002) Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. CIRC RES , 90 (11) 1153 - 1158. 10.1161/01.RES.0000020562.07492.D4.

MacAllister, R; Hingorani, AD; Casas, JP; (2004) Ximelagatran or warfarin in atrial fibrillation? LANCET , 363 (9410) 735 - 736.

Mayahi, L; Heales, S; Owen, D; Casas, JP; Harris, J; MacAllister, RJ; Hingorani, AD; (2007) (6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm. ARTERIOSCL THROM VAS , 27 (6) 1334 - 1339. 10.1161/ATVBAHA.107.142257.

Mayahi, L; Mason, L; Bleasdale-Barr, K; Donald, A; Trender-Gerhard, I; Sweeney, MG; ... Hingorani, AD; + view all (2010) Endothelial, Sympathetic, and Cardiac Function in Inherited (6R)-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin Deficiency. CIRC-CARDIOVASC GENE , 3 (6) 513 - 522. 10.1161/CIRCGENETICS.110.957605.

Mayahi, L; Mason, L; Storry, C; Donald, A; Trender-Gherhard, I; Mathias, C; ... Hingorani, A; + view all (2006) Endothelial, sympathetic and cardiac function in inherited 6R-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin deficiency. CIRCULATION , 114 (18) 283 - 283.

McKay, GJ; Patterson, CC; Chakravarthy, U; Dasari, S; Klaver, CC; Vingerling, JR; ... Silvestri, G; + view all (2011) Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat , 32 (12) 1407 - 1416. 10.1002/humu.21577.

McKay, GJ; Silvestri, G; Chakravarthy, U; Dasari, S; Fritsche, LG; Weber, BH; ... Patterson, CC; + view all (2011) Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People. AM J EPIDEMIOL , 173 (12) 1357 - 1364. 10.1093/aje/kwr015.

Minassian, C; D'Aiuto, F; Hingorani, AD; (2011) Invasive Dental Treatment and Risk for Vascular Events RESPONSE. ANN INTERN MED , 154 (6) 442 - 442. 10.1059/0003-4819-154-6-201103150-00016.

Minassian, C; D'Aiuto, F; Hingorani, AD; Smeeth, L; (2010) Invasive Dental Treatment and Risk for Vascular Events A Self-Controlled Case Series. ANN INTERN MED , 153 (8) 499 - W181.

Munafò, MR; Timofeeva, MN; Morris, RW; Prieto-Merino, D; Sattar, N; Brennan, P; ... Davey Smith, G; + view all (2012) Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. J Natl Cancer Inst , 104 (10) 740 - 748. 10.1093/jnci/djs191.

Newcombe, PJ; Verzilli, C; Casas, JP; Hingorani, AD; Smeeth, L; Whittaker, JC; (2009) Multilocus Bayesian Meta-Analysis of Gene-Disease Associations. AM J HUM GENET , 84 (5) 567 - 580. 10.1016/j.ajhg.2009.04.001.

Noori, M; Donald, AE; Angelakopoulou, A; Hingorani, AD; Williams, DJ; (2010) Prospective Study of Placental Angiogenic Factors and Maternal Vascular Function Before and After Preeclampsia and Gestational Hypertension. CIRCULATION , 122 (5) 478 - 487. 10.1161/CIRCULATIONAHA.109.895458.

O'Neill, SG; Pego-Reigosa, JM; Hingorani, AD; Bessant, R; Isenberg, DA; Rahman, A; (2009) Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus. RHEUMATOLOGY , 48 (5) 573 - 575. 10.1093/rheumatology/kep037.

Palmer, ND; McDonough, CW; Hicks, PJ; Roh, BH; Wing, MR; An, SS; ... Sladek, R; + view all (2012) A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One , 7 (1) , Article e29202 . 10.1371/journal.pone.0029202. Green and gold open access
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Papp, AC; Pinsonneault, JK; Wang, D; Newman, LC; Gong, Y; Johnson, JA; ... Sadee, W; + view all (2012) Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. PLoS One , 7 (3) , Article e31930 . 10.1371/journal.pone.0031930. Green and gold open access
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Repapi, E; Sayers, I; Wain, LV; Burton, PR; Johnson, T; Obeidat, M; ... NSHD Resp Study Team,; + view all (2010) Genome-wide association study identifies five loci associated with lung function. NAT GENET , 42 (1) 36 - U51. 10.1038/ng.501.

Sarwar, N; Sandhu, MS; Ricketts, SL; Butterworth, AS; Di Angelantonio, E; Boelcholdt, SM; ... Triglyceride Coronary Dis Genetics,; + view all (2010) Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. LANCET , 375 (9726) 1634 - 1639.

Sattar, N; Hingorani, AD; (2009) C-Reactive Protein and Prognosis in Diabetes: Getting to the Heart of the Matter. DIABETES , 58 (4) 798 - 799. 10.2337/db08-1788.

Savvidou, MD; Hingorani, AD; Tsikas, D; Frolich, JC; Vallance, P; Nicolaides, KH; (2003) Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. LANCET , 361 (9368) 1511 - 1517.

Savvidou, MD; Lees, CC; Parra, M; Hingorani, AD; Nicolaides, KH; (2002) Levels of C-reactive protein in pregnant women who subsequently develop pre-eclampsia. BJOG-INT J OBSTET GY , 109 (3) 297 - 301.

Savvidou, MD; Noori, M; Anderson, JM; Hingorani, AD; Nicolaides, KH; (2008) Maternal endothelial function and serum concentrations of placental growth factor and soluble endoglin in women with abnormal placentation. ULTRASOUND OBST GYN , 32 (7) 871 - 876. 10.1002/uog.6126.

Savvidou, MD; Vallance, PJT; Nicolaides, KH; Hingorani, AD; (2001) Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy. HYPERTENSION , 38 (6) 1289 - 1293.

Savvidou, MD; Yu, CK; Harland, LC; Hingorani, AD; Nicolaides, KH; (2006) Maternal serum concentration of soluble fms-like tyrosine kinase 1 and vascular endothelial growth factor in women with abnormal uterine artery Doppler and in those with fetal growth restriction. AM J OBSTET GYNECOL , 195 (6) 1668 - 1673. 10.1016/j.ajog.2006.03.065.

Saxena, R; Elbers, CC; Guo, Y; Peter, I; Gaunt, TR; Mega, JL; ... Keating, BJ; + view all (2012) Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet , 90 (3) 410 - 425. 10.1016/j.ajhg.2011.12.022.

Saxena, R; Hivert, MF; Langenberg, C; Tanaka, T; Pankow, JS; Vollenweider, P; ... MAGIC Investigators,; + view all (2010) Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. NAT GENET , 42 (2) 142 - U75. 10.1038/ng.521.

Sayers, A; Timpson, NJ; Sattar, N; Deanfield, J; Hingorani, AD; Davey-Smith, G; Tobias, JH; (2010) Adiponectin and Its Association With Bone Mass Accrual in Childhood. J BONE MINER RES , 25 (10) 2212 - 2220. 10.1002/jbmr.116.

Serrano, NC; Casas, JP; Diaz, LA; Paez, C; Mesa, CM; Cifuentes, R; ... Lopez-Jaramillo, P; + view all (2004) Endothelial NO synthase genotype and risk of preeclampsia - A multicenter case-control study. HYPERTENSION , 44 (5) 702 - 707. 10.1161/01.HYP.0000143483.66701.ec.

Serrano, NC; Diaz, LA; Casas, JP; Hingorani, AD; de Lucca, DM; Paez, MC; (2010) Frequency of eNOS polymorphisms in the Colombian general population. BMC GENET , 11 , Article 54. 10.1186/1471-2156-11-54. Gold open access

Serrano, NC; Diaz, LA; Paez, MC; Mesa, CM; Cifuentes, R; Monterrosa, A; ... Casas, JP; + view all (2006) Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: Evidence of small-study bias. PLOS MED , 3 (12) , Article e520. 10.1371/journal.pmed.0030520. Gold open access

Shah, AD; Nicholas, O; Timmis, AD; Feder, G; Abrams, KR; Chen, RL; ... Hemingway, H; + view all (2011) Threshold Haemoglobin Levels and the Prognosis of Stable Coronary Disease: Two New Cohorts and a Systematic Review and Meta-Analysis. PLoS Medicine , 8 (5) , Article e1000439. 10.1371/journal.pmed.1000439. Green and gold open access
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Shah, S; Casas, JP; Drenos, F; Whittaker, J; Deanfield, J; Swerdlow, DI; ... Hingorani, AD; + view all (2013) Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis. Circ Cardiovasc Genet , 6 (1) 63 - 72. 10.1161/CIRCGENETICS.112.963140.

Shah, S; Casas, JP; Gaunt, TR; Cooper, J; Drenos, F; Zabaneh, D; ... Humphries, SE; + view all (2013) Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. Eur Heart J , 34 (13) 972 - 981. 10.1093/eurheartj/ehs243.

Shah, S; Casas, JP; Gaunt, TR; Cooper, J; Drenos, F; Zabaneh, D; ... Humphries, SE; + view all (2013) Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. Eur Heart J , 34 (13) 972 - 981. 10.1093/eurheartj/ehs243.

Shah, S; Nelson, CP; Gaunt, TR; van der Harst, P; Barnes, T; Braund, PS; ... Samani, NJ; + view all (2011) Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circ Cardiovasc Genet , 4 (6) 626 - 635. 10.1161/CIRCGENETICS.111.960203.

Shah, T; Casas, JP; Cooper, JA; Tzoulaki, I; Sofat, R; McCormack, V; ... Hingorani, AD; + view all (2009) Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts (vol 38, pg 217, 2009). INT J EPIDEMIOL , 38 (3) 890 - 890. 10.1093/ije/dyp206.

Shah, T; Casas, JP; Cooper, JA; Tzoulaki, I; Sofat, R; McCormack, V; ... Hingorani, AD; + view all (2009) Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts. INT J EPIDEMIOL , 38 (1) 217 - 231. 10.1093/ije/dyn217.

Shah, T; Casas, JP; Cooper, JA; Tzoulaki, I; Sofat, R; Smeeth, L; ... Hingorani, AD; + view all (2008) CRITICAL APPRAISAL OF THE UTILITY OF CRP MEASUREMENT IN THE PREDICTION OF CARDIOVASCULAR EVENTS. ATHEROSCLEROSIS SUPP , 9 (1) 10 - 10.

Shah, T; Engmann, J; Dale, C; Shah, S; White, J; Giambartolomei, C; ... UCLEB Consortium,; + view all (2013) Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS One , 8 (8) e71345 - ?. 10.1371/journal.pone.0071345.

Shah, T; Newcombe, P; Smeeth, L; Addo, J; Casas, JP; Whittaker, J; ... Hingorani, AD; + view all (2010) Ancestry as a Determinant of Mean Population C-Reactive Protein Values Implications for Cardiovascular Risk Prediction. CIRC-CARDIOVASC GENE , 3 (5) 436 - U113. 10.1161/CIRCGENETICS.110.957431.

Shah, T; Zabaneh, D; Gaunt, T; Swerdlow, DI; Shah, S; Talmud, PJ; ... Casas, JP; + view all (2013) Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. Circ Cardiovasc Genet , 6 (2) 163 - 170. 10.1161/CIRCGENETICS.112.964254.

Sharma, P; Hingorani, A; Jia, H; Ashby, M; Hopper, R; Clayton, D; Brown, MJ; (1998) Positive association of tyrosine hydroxylase microsatellite marker to essential hypertension. HYPERTENSION , 32 (4) 676 - 682.

Smeeth, L; Casas, JP; Hingorani, AD; (2007) The role of infection in cardiovascular disease: more support but many questions remain. EUR HEART J , 28 (10) 1178 - 1179. 10.1093/eurheartj/ehm035.

Smeeth, L; Casas, JP; Hingorani, AD; (2007) The role of infection in cardiovascular disease: more support but many questions remain. Eur Heart J , 28 (10) 1178 - 1179. 10.1093/eurheartj/ehm073.

Smeeth, L; Hingorani, AD; (2010) Short-term vascular risk: time to take notice? NAT REV CARDIOL , 7 (7) 409 - 412. 10.1038/nrcardio.2010.64.

Smith, AJ; Howard, P; Shah, S; Eriksson, P; Stender, S; Giambartolomei, C; ... Humphries, SE; + view all (2012) Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays. PLoS Genetics , 8 (8) , Article e1002908. 10.1371/journal.pgen.1002908. Green and gold open access
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Sofat, R; Casas, JP; Grosso, AM; Prichard, BN; Smeeth, L; MacAllister, R; Hingorani, AD; (2012) Could NICE guidance on the choice of blood pressure lowering drugs be simplified? BMJ , 344 d8078 - ?.

Sofat, R; Casas, JP; Grosso, AM; Prichard, BNC; Smeeth, L; MacAllister, R; Hingorani, AD; (2012) Could NICE guidance on the choice of blood pressure lowering drugs be simplified? BRITISH MEDICAL JOURNAL , 344 , Article ARTN d8078. 10.1136/bmj.d8078.

Sofat, R; Casas, JP; Kumari, M; Talmud, PJ; Ireland, H; Kivimaki, M; ... Hingorani, AD; + view all (2010) Genetic variation in complement factor H and risk of coronary heart disease: Eight new studies and a meta-analysis of around 48,000 individuals. ATHEROSCLEROSIS , 213 (1) 184 - 190. 10.1016/j.atherosclerosis.2010.07.021.

Sofat, R; Casas, JP; Webster, AR; Bird, AC; Mann, SS; Yates, JR; ... Hingorani, AD; + view all (2012) Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype. Int J Epidemiol , 41 (1) 250 - 262. 10.1093/ije/dyr204.

Sofat, R; Hingorani, AD; Smeeth, L; Humphries, SE; Talmud, PJ; Cooper, J; ... Casas, JP; + view all (2010) Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms. CIRCULATION , 121 (1) 52 - 62. 10.1161/CIRCULATIONAHA.109.865444. Gold open access

Sofat, R; Mangione, PP; Gallimore, JR; Hakobyan, S; Hughes, TR; Shah, T; ... Hingorani, AD; + view all (2013) Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay. J Immunol Methods , 390 (1-2) 63 - 73. 10.1016/j.jim.2013.01.009.

Soler Artigas, M; Loth, DW; Wain, LV; Gharib, SA; Obeidat, M; Tang, W; ... Tobin, MD; + view all (2011) Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet , 43 (11) 1082 - 1090. 10.1038/ng.941.

Soler Artigas, M; Wain, LV; Repapi, E; Obeidat, M; Sayers, I; Burton, PR; ... SpiroMeta Consortium,; + view all (2011) Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med , 184 (7) 786 - 795. 10.1164/rccm.201102-0192OC.

Staines-Urias, E; Paez, MC; Doyle, P; Dudbridge, F; Serrano, NC; Ioannidis, JP; ... Casas, JP; + view all (2012) Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis. Int J Epidemiol , 41 (6) 1764 - 1775. 10.1093/ije/dys162.

Sutaria, S; Philipson, P; Fitzpatrick, NK; Abrams, K; Moreno, SG; Timmis, A; ... Hemingway, H; + view all (2012) Translational phases of evidence in a prognostic biomarker: a systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease. Heart , 98 (8) 615 - 622. 10.1136/heartjnl-2011-300862.

Talmud, PJ; Cooper, JA; Gaunt, T; Holmes, MV; Shah, S; Palmen, J; ... Humphries, SE; + view all (2011) Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies. DIABETOLOGIA , 54 (7) 1710 - 1719. 10.1007/s00125-011-2108-6. Gold open access

Talmud, PJ; Cooper, JA; Palmen, J; Lovering, R; Drenos, F; Hingorani, AD; Humphries, SE; (2008) Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men. CLIN CHEM , 54 (3) 467 - 474. 10.1373/clinchem.2007.095489.

Talmud, PJ; Drenos, F; Shah, S; Shah, T; Palmen, J; Verzilli, C; ... BRIGHT Consortium,; + view all (2009) Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip. AM J HUM GENET , 85 (5) 628 - 642. 10.1016/j.ajhg.2009.10.014. Gold open access

Talmud, PJ; Hingorani, AD; Cooper, JA; Marmot, MG; Brunner, EJ; Kumari, M; ... Humphries, SE; + view all (2010) Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study. BRIT MED J , 340 , Article b4838. 10.1136/bmj.b4838. Gold open access

Talmud, PJ; Shah, S; Whittall, R; Futema, M; Howard, P; Cooper, JA; ... Humphries, SE; + view all (2013) Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. Lancet , 381 (9874) 1293 - 1301. 10.1016/S0140-6736(12)62127-8.

Taylor, AE; Guthrie, PAI; Smith, GD; Golding, J; Sattar, N; Hingorani, AD; ... Day, INM; + view all (2011) IQ, Educational Attainment, Memory and Plasma Lipids: Associations with Apolipoprotein E Genotype in 5995 Children. BIOL PSYCHIAT , 70 (2) 152 - 158. 10.1016/j.biopsych.2010.10.033.

Tonetti, M.S.; D'Aiuto, F.; Nibali, L.; Donald, A.; Storry, C.; Parkar, M.; ... Deanfield, J.; + view all (2007) Treatment of periodontitis and endothelial function. New England Journal of Medicine , 356 (9) pp. 911-920. 10.1056/NEJMoa063186. Green open access
file

Tonetti, MS; D'Aiuto, F; Nibali, L; Donald, A; Storry, C; Parkar, M; ... Deanfield, J; + view all (2007) Treatment of periodontitis and endothelial function. NEW ENGL J MED , 356 (9) 911 - 920.

Tsakos, G; Sabbah, W; Hingorani, AD; Netuveli, G; Donos, N; Watt, RG; D'Aiuto, F; (2010) Is periodontal inflammation associated with raised blood pressure? Evidence from a National US survey. J HYPERTENS , 28 (12) 2386 - 2393. 10.1097/HJH.0b013e32833e0fe1.

Ulrich, S; Hingorani, AD; Martin, J; Vallance, P; (2000) What is the optimal age for starting lipid lowering treatment? A mathematical model. BRIT MED J , 320 (7242) 1134 - 1140.

Ulrich, S; Hingorani, AD; Martin, J; Vallance, P; (2000) What is the optimal age for starting lipid lowering treatment? A mathematical model. BMJ , 320 (7242) 1134 - 1140.

Ulrich, S; Hingorani, AD; Martin, J; Vallance, P; (1999) Lifetime risk of developing coronary heart disease. LANCET , 353 (9156) 925 - 925.

Vallance, P; Hingorani, AD; Ulrich, S; (2000) Optimal age for starting lipid lowering treatment - Adjusted data do not justify a lower optimal age - Reply. BRIT MED J , 321 (7261) 638 - 638.

Verzilli, C; Shah, T; Casas, JP; Chapman, J; Sandhu, M; Debenham, SL; ... Hingorani, AD; + view all (2008) Bayesian meta-analysis of genetic association studies with different sets of markers. AM J HUM GENET , 82 (4) 859 - 872. 10.1016/j.ajhg.2008.01.016.

Vimaleswaran, KS; Berry, DJ; Lu, C; Tikkanen, E; Pilz, S; Hiraki, LT; ... Hyppönen, E; + view all (2013) Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med , 10 (2) , Article e1001383 . 10.1371/journal.pmed.1001383. Green and gold open access
file

Welsh, P; Polisecki, E; Robertson, M; Jahn, S; Buckley, BM; de Craen, AJM; ... Sattar, N; + view all (2010) Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach. J CLIN ENDOCR METAB , 95 (1) 93 - 99. 10.1210/jc.2009-1064.

Wensley, F; Gao, P; Burgess, S; Kaptoge, S; Di Angelantonio, E; Shah, T; ... WOSCOPS,; + view all (2011) Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BRIT MED J , 342 , Article d548. 10.1136/bmj.d548.

Yiannakouris, N; Cooper, JA; Shah, S; Drenos, F; Ireland, HA; Stephens, JW; ... Humphries, SE; + view all (2012) IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk. Nutrition, Metabolism and Cardiovascular Diseases , 22 (12) 1024 - 1030. 10.1016/j.numecd.2011.05.009. Green and gold open access
file

Yiannakouris, N; Cooper, JA; Shah, S; Ireland, H; Stephens, JW; Li, KW; ... Humphries, SE; + view all (2010) Genetic variants near IRS1 and their association with type 2 diabetes, hyperinsulinemia and insulin resistance. DIABETES OBES METAB , 12 46 - 46.

Yu, CK; Casas, JP; Savvidou, MD; Sahemey, MK; Nicolaides, KH; Hingorani, AD; (2006) Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis. BMC Pregnancy and Childbirth , 6 , Article 7. 10.1186/1471-2393-6-7. Green and gold open access
file

Zabaneh, D; Gaunt, TR; Kumari, M; Drenos, F; Shah, S; Berry, D; ... Humphries, SE; + view all (2011) Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip. ANN HUM GENET , 75 456 - 467. 10.1111/j.1469-1809.2011.00654.x.

Zabaneh, D; Kumari, M; Sandhu, M; Wareham, N; Wainwright, N; Papamarkou, T; ... Humphries, SE; + view all (2011) Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts. ATHEROSCLEROSIS , 217 (2) 447 - 451. 10.1016/j.atherosclerosis.2011.04.015.

Proceedings paper

Alves, JD; Clapp, BR; Stidwill, R; Chen, PP; Hingorani, AD; Singer, M; Isenberg, DA; (2004) Human monoclonal IGG anticardiolipin antibodies induce nitric oxide synthase expression. In: THROMBOSIS RESEARCH. (pp. 615 - 615). PERGAMON-ELSEVIER SCIENCE LTD

Bautista, LE; Casas, JP; Smeeth, L; Hingorani, AD; (2005) Estimation of bias in "Mendelian triangulation" studies. In: AMERICAN JOURNAL OF EPIDEMIOLOGY. (pp. S73 - S73). OXFORD UNIV PRESS INC

Brull, DJ; Serrano, N; Zito, F; Jones, L; Montgomery, HE; Rumley, A; ... Hingorani, AD; + view all (2003) A polymorphism in the human CRP gene influences basal and stimulated CRP levels: Implications for the prediction and pathogenesis of coronary heart disease. In: ATHEROSCLEROSIS. (pp. 198 - 198). ELSEVIER SCI IRELAND LTD

Brull, DJ; Serrano, N; Zito, F; Jones, L; Montgomery, HE; Rumley, A; ... Hingorani, AD; + view all (2003) A polymorphism in the human CRP gene influences basal and stimulated CRP levels: Implications for the prediction and pathogenesis of coronary heart disease. In: ATHEROSCLEROSIS. (pp. 192 - 192). ELSEVIER SCI IRELAND LTD

Casas, JP; Bautista, LE; Hingorani, AD; Sharma, P; (2004) Plasma homocysteine, and ischaemic stroke: "Mendelian randomization" provides further evidence of causal link. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 1218 - 1218). B M J PUBLISHING GROUP

Clapp, B; Hirschfield, G; MacAllister, R; Gallimore, R; Vallance, P; Pepys, M; Hingorani, A; (2003) C-reactive protein alters vascular reactivity by increasing nitric oxide production. In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. (pp. 319A - 319A). ELSEVIER SCIENCE INC

Holmes, MV; Shah, T; Vickery, C; Smeeth, L; Hingorani, AD; Casas, JP; (2009) A FIELD SYNOPIS OF PHARMACOGENETIC STUDIES. In: ATHEROSCLEROSIS. (pp. E5 - E5). ELSEVIER IRELAND LTD

Langenberg, C; Jensen, AC; Barker, A; Brunner, EJ; Hingorani, AD; Kumari, M; ... Witte, DR; + view all (2010) Age-dependent genetic effects on post-load glucose during 18 years of follow-up of the Whitehall II Cohort. In: DIABETOLOGIA. (pp. S122 - S123). SPRINGER

Noori, M; Donald, A; Hingorani, A; Williams, DJ; (2007) A prospective study of maternal endothelial function, angiogenic factors and placental function in women at risk of pre-eclampsia. In: Journal of Human Hypertension. (pp. 832 - 832).

Santhanakrishnan, VK; Berry, DJ; Hingorani, AD; Whittaker, JC; Jarvelin, MR; Hypponen, E; (2011) Obesity is a Causal Risk Factor For Low Vitamin D Status: A Bi-Directional Mendelian Randomization Study on 40,000 Individuals. In: OBESITY. (pp. S231 - S231). NATURE PUBLISHING GROUP

Shah, S; Drenos, F; Shah, T; Palmen, J; Vezzili, C; Sofat, R; ... Hingorani, AD; + view all (2009) IDENTIFICATION OF GENES ASSOCIATED WITH QT INTERVAL USING THE 50K CARDIO-METABOLIC SNP CHIP: RESULTS FROM THE WHITEHALL II STUDY. In: ATHEROSCLEROSIS. (pp. E11 - E11). ELSEVIER IRELAND LTD

Shah, T; Casas, J; Cooper, J; Hawe, E; Stephens, J; Hurel, S; ... Hingorani, AD; + view all (2005) Mendelian randomisation and disease risk estimates for C-reactive protein (CRP). In: ATHEROSCLEROSIS. (pp. S4 - S5). ELSEVIER IRELAND LTD

Shah, T; Cooper, JA; Casas, JP; Pearce, K; Tinworth, L; Hingorani, AD; ... Humphries, SE; + view all (2006) CRP in the prediction and pathogenesis of cardiovascular events in middle-aged men; Results from the NPHSII study. In: ATHEROSCLEROSIS. (pp. S3 - S3). ELSEVIER IRELAND LTD

Shah, T; Newcombe, P; Addo, J; Casas, JP; Smeeth, L; Whittaker, J; Hingorani, AD; (2009) CONSIDERATION OF ETHNICITY IN CORONARY RISK PREDICTION USING CRP. In: ATHEROSCLEROSIS. (pp. E11 - E11). ELSEVIER IRELAND LTD

Sharma, P; Whittaker, J; Casas, JP; Hingorani, AD; Ariyaratnam, R; (2007) Genetics of ischaemic stroke in ethnic minorities. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 212 - 212). B M J PUBLISHING GROUP

Tzoulaki, I; Shah, T; Ireland, H; Casas, JP; Hingorani, AD; Humphries, SE; Fowkes, FGR; (2007) C-reactive protein and interleukin-6 polymorphisms in relation to subclinical atherosclerotic disease. In: CIRCULATION. (pp. E296 - E296). LIPPINCOTT WILLIAMS & WILKINS

This list was generated on Fri Apr 18 09:53:11 2014 BST.