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Number of items: 69.

A

Abis, G; Charles, RL; Eaton, P; Conte, MR; (2019) Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain. Protein Expression and Purification , 153 pp. 105-113. 10.1016/j.pep.2018.09.001. Green open access
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Abis, G; Charles, RL; Kopec, J; Yue, WW; Atkinson, RA; Bui, TTT; Lynham, S; ... Conte, MR; + view all (2019) 15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism. Communications Biology , 2 , Article 188. 10.1038/s42003-019-0426-2. Green open access
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Aloum, L; Brimson, CA; Zhyvoloup, A; Baines, R; Baković, J; Filonenko, V; Thompson, CRL; (2019) Coenzyme A and protein CoAlation levels are regulated in response to oxidative stress and during morphogenesis in Dictyostelium discoideum. Biochemical and Biophysical Research Communications , 511 (2) pp. 294-299. 10.1016/j.bbrc.2019.02.031. Green open access
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Arnvig, K; (2019) Riboswitches: choosing the best platform. [Review]. Biochemical Society Transactions (In press).

Ashford, P; Pang, CSM; Moya-García, AA; Adeyelu, T; Orengo, CA; (2019) A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations. Scientific Reports , 9 , Article 263. 10.1038/s41598-018-36401-4. Green open access
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B

Baskozos, G; Dawes, JM; Austin, JS; Antunes-Martins, A; McDermott, L; Clark, AJ; Trendafilova, T; ... Bennett, DL; + view all (2019) Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury. Pain , 160 (2) pp. 463-485. 10.1097/j.pain.0000000000001416. Green open access
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Bowers, K; (2019) RNA Interference-Mediated Inhibition of ESCRT in Mammalian Cells. The ESCRT Complexes pp. 305-318. 10.1007/978-1-4939-9492-2_22.

Britt, HM; García-Herrero, CA; Denny, PW; Mosely, JA; Sanderson, JM; (2019) Lytic reactions of drugs with lipid membranes. Chemical Science , 10 (3) pp. 674-680. 10.1039/c8sc04831b. Green open access
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Britt, HM; Mosely, JA; Sanderson, JM; (2019) The influence of cholesterol on melittin lipidation in neutral membranes. Physical Chemistry Chemical Physics , 21 (2) pp. 631-640. 10.1039/c8cp06661b.

C

Carecchio, M; Invernizzi, F; Gonzàlez-Latapi, P; Panteghini, C; Zorzi, G; Romito, L; Leuzzi, V; ... Nardocci, N; + view all (2019) Frequency and phenotypic spectrum of KMT2B dystonia in childhood: A single-center cohort study. Movement Disorders 10.1002/mds.27771. (In press).

Carnevali, PBM; Schulz, F; Castelle, C; Kantor, R; Shih, P; Sharon, I; Santini, JM; ... Banfield, JF; + view all (2019) Hydrogen-based metabolism as an ancestral trait in lineages sibling to the Cyanobacteria. Nature Communications , 10 , Article 463. 10.1038/s41467-018-08246-y. Green open access
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Castaño-Díez, D; Zanetti, G; (2019) In situ structure determination by subtomogram averaging. Current Opinion in Structural Biology , 58 pp. 68-75. 10.1016/j.sbi.2019.05.011. Green open access
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Chelban, V; Wilson, MP; Warman Chardon, J; Vandrovcova, J; Zanetti, MN; Zamba-Papanicolaou, E; Efthymiou, S; ... SYNaPS Study Group, .; + view all (2019) PDXK mutations cause polyneuropathy responsive to PLP supplementation. Annals of Neurology 10.1002/ana.25524. (In press). Green open access
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Cheung, ACM; (2019) Building transcription complexes. Nature Structural & Molecular Biology , 26 (1-2) 10.1038/s41594-018-0174-x. Green open access
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Codina, N; Hilton, D; Zhang, C; Chakroun, N; Ahmad, SS; Perkins, SJ; Dalby, PA; (2019) An Expanded Conformation of an Antibody Fab Region by X-Ray Scattering, Molecular Dynamics and smFRET Identifies an Aggregation Mechanism. Journal of Molecular Biology 10.1016/j.jmb.2019.02.009. (In press). Green open access
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D

Dagil, L; Troelsen, KS; Bolt, G; Thim, L; Wu, B; Zhao, X; Tuddenham, EGD; ... Hansen, DF; + view all (2019) Interaction Between the a3 Region of Factor VIII and the TIL'E’ Domains of the von Willebrand Factor. Biophysical Journal , 117 (3) pp. 479-489. 10.1016/j.bpj.2019.07.007. Green open access
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Dagil, R; Ball, NJ; Ogrodowicz, RW; Hobor, F; Purkiss, AG; Kelly, G; Martin, SR; ... Ramos, A; + view all (2019) IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties. Nucleic Acids Research , Article gkz136. 10.1093/nar/gkz136. (In press). Green open access
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Deville, C; Franke, K; Mogk, A; Bukau, B; Saibil, HR; (2019) Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor. Cell Reports , 27 (12) 3433-3446.e4. 10.1016/j.celrep.2019.05.075. Green open access
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Devoto, A; Santini, JM; Olm, M; Anantharaman, K; Munk, P; Archie, E; Turnbaugh, P; ... Banfield, J; + view all (2019) Megaphages infect Prevotella and variants are widespread in gut microbiomes. Nature Microbiology , 4 pp. 693-700. 10.1038/s41564-018-0338-9. Green open access
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E

Eldrid, CFS; Ujma, J; Kalfas, S; Tomczyk, N; Giles, K; Morris, MR; Thalassinos, K; (2019) Gas Phase Stability of Protein Ions in a Cyclic Ion Mobility Spectrometry Traveling Wave Device. Analytical Chemistry 10.1021/acs.analchem.8b05641. (In press). Green open access
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F

Fedorec, AJH; Ozdemir, T; Doshi, A; Ho, Y-K; Rosa, L; Rutter, J; Velazquez, O; ... Barnes, CP; + view all (2019) Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli. iScience 10.1016/j.isci.2019.03.019. (In press). Green open access
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Fitzpatrick, AW; Saibil, HR; (2019) Cryo-EM of amyloid fibrils and cellular aggregates. Current Opinion in Structural Biology , 58 pp. 34-42. 10.1016/j.sbi.2019.05.003. (In press). Green open access
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Fumagalli, M; Camus, SM; Diekmann, Y; Burke, A; Camus, M; Norman, P; Joseph, A; ... Brodsky, F; + view all (2019) Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism. eLife , 2019 (8) , Article e41517. 10.7554/eLife.41517. Green open access
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G

Gabelica, V; Shvartsburg, AA; Afonso, C; Barran, P; Benesch, JLP; Bleiholder, C; Bowers, MT; ... Wyttenbach, T; + view all (2019) Recommendations for reporting ion mobility Mass Spectrometry measurements. Mass Spectrometry Review 10.1002/mas.21585. (In press). Green open access
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Gout, I; (2019) Coenzyme A: a protective thiol in bacterial antioxidant defence. Biochemical Society Transactions , 47 (1) pp. 469-476. 10.1042/BST20180415.

Gradeci, D; Bove, A; Charras, G; Lowe, AR; Banerjee, S; (2019) Single-cell approaches to cell competition: high-throughput imaging, machine learning and simulations. Seminars in Cancer Biology 10.1016/j.semcancer.2019.05.007. (In press).

H

Hansen, DF; (2019) Using Deep Neural Networks to Reconstruct Non-uniformly Sampled NMR Spectra. Journal of Biomolecular NMR 10.1007/s10858-019-00265-1. (In press). Green open access
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Hartley, AM; Lukoyanova, N; Zhang, Y; Cabrera-Orefice, A; Arnold, S; Meunier, B; Pinotsis, N; (2019) Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1. Nature Structural and Molecular Biology , 26 pp. 78-83. 10.1038/s41594-018-0172-z. Green open access
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Heifetz, A; James, T; Southey, M; Morao, I; Aldeghi, M; Sarrat, L; Fedorov, DG; ... Townsend-Nicholson, A; + view all (2019) Characterising GPCR–ligand interactions using a fragment molecular orbital-based approach. Current Opinion in Structural Biology , 55 pp. 85-92. 10.1016/j.sbi.2019.03.021.

Hernández Durán, A; Greco, TM; Vollmer, B; Cristea, IM; Grünewald, K; Topf, M; (2019) Protein interactions and consensus clustering analysis uncover insights into herpesvirus virion structure and function relationships. PLoS Biology , 17 (6) , Article e3000316. 10.1371/journal.pbio.3000316. Green open access
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Hospenthal, MK; Waksman, G; (2019) The Remarkable Biomechanical Properties of the Type 1 Chaperone-Usher Pilus: A Structural and Molecular Perspective. Microbiology Spectrum , 7 (1) pp. 1-10. 10.1128/microbiolspec.PSIB-0010-2018.

Hui, GK; Gardener, AD; Begum, H; Eldrid, C; Thalassinos, K; Gor, J; Perkins, SJ; (2019) The solution structure of the human IgG2 subclass is distinct from those for human IgG1 and IgG4 providing an explanation for their discrete functions. Journal of Biological Chemistry 10.1074/jbc.RA118.007134. (In press). Green open access
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I

Ireland, S; Martin, ACR; (2019) ZincBind - The Database of Zinc Binding Sites. Database : the Journal of Biological Databases and Curation , 2019 Green open access
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J

James, JMB; Cryar, A; Thalassinos, K; (2019) Optimization Workflow for the Analysis of Cross-Linked Peptides Using a Quadrupole Time-of-Flight Mass Spectrometer. Analytical Chemistry , 91 (3) pp. 1808-1814. 10.1021/acs.analchem.8b02319. Green open access
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K

Kuzmanic, A; Pritchard, RB; Hansen, DF; Gervasio, FL; (2019) Importance of the Force Field Choice in Capturing Functionally Relevant Dynamics in the von Willebrand Factor. The Journal of Physical Chemistry Letters , 10 (8) pp. 1928-1934. 10.1021/acs.jpclett.9b00517. Green open access
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M

Mackenzie, HW; Flemming Hansen, D; (2019) Arginine Side-Chain Hydrogen Exchange: Quantifying Arginine Side-Chain Interactions in Solution. ChemPhysChem , 20 (2) , Article Special Issue: BioNMR Spectroscopy. 10.1002/cphc.201800598. Green open access
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Magno, L; Lessard, CB; Martins, M; Lang, V; Cruz, P; Asi, Y; Katan, M; ... Whiting, PJ; + view all (2019) Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph. Alzheimer's Research & Therapy , 11 , Article 16. 10.1186/s13195-019-0469-0. Green open access
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Malerba, A; Klein, P; Lu-Nguyen, N; Cappellari, O; Strings-Ufombah, V; Harbaran, S; Roelvink, P; ... Dickson, G; + view all (2019) Established PABPN1 intranuclear inclusions in OPMD muscle can be efficiently reversed by AAV-mediated knock-down and replacement of mutant expanded PABPN1. Human Molecular Genetics 10.1093/hmg/ddz167. (In press).

Marabelli, C; Marrocco, B; Pilotto, S; Chittori, S; Picaud, S; Marchese, S; Ciossani, G; ... Mattevi, A; + view all (2019) A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Reports , 27 (2) pp. 387-399. 10.1016/j.celrep.2019.03.061. Green open access
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Markova, EA; Zanetti, G; (2019) Visualizing membrane trafficking through the electron microscope: cryo-tomography of coat complexes. Acta Crystallographica Section D: Structural Biology , 75 (5) pp. 467-474. 10.1107/S2059798319005011. Green open access
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Matheus Carnevali, PB; Schulz, F; Castelle, CJ; Kantor, RS; Shih, PM; Sharon, I; Santini, JM; ... Banfield, JF; + view all (2019) Author Correction: Hydrogen-based metabolism as an ancestral trait in lineages sibling to the Cyanobacteria. [Corrigendum]. Nature Communications , 10 (1) , Article 1451. 10.1038/s41467-019-09423-3. Green open access
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Menneteau, T; Fabre, B; Garrigues, L; Stella, A; Zivkovic, D; Roux-Dalvai, F; Mouton-Barbosa, E; ... Bousquet, M-P; + view all (2019) Mass spectrometry-based absolute quantification of 20S proteasome status for controlled ex-vivo expansion of Human Adipose-derived Mesenchymal Stromal/Stem Cells. Molecular & Cellular Proteomics 10.1074/mcp.RA118.000958. (In press). Green open access
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Montoya, DJ; Andrade, P; Silva, BJA; Teles, RMB; Ma, F; Bryson, B; Sadanand, S; ... Modlin, RL; + view all (2019) Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune Response. Cell Reports , 26 (13) 3574-3585.e3. 10.1016/j.celrep.2019.02.109. Green open access
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N

Nimmo, IC; Barbrook, AC; Lassadi, I; Chen, JE; Geisler, K; Smith, AG; Aranda, M; ... Howe, CJ; + view all (2019) Genetic transformation of the dinoflagellate chloroplast. eLife , 8 , Article e45292. 10.7554/eLife.45292. Green open access
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P

Patel, A; Perrin, AJ; Flynn, HR; Bisson, C; Withers-Martinez, C; Treeck, M; Flueck, C; ... Baker, DA; + view all (2019) Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery. PLoS Biology , 17 (5) , Article e3000264. 10.1371/journal.pbio.3000264. (In press).

Peran, I; Holehouse, AS; Carrico, IS; Pappu, RV; Bilsel, O; Raleigh, DP; (2019) Unfolded states under folding conditions accommodate sequence-specific conformational preferences with random coil-like dimensions. Proceedings of the National Academy of Sciences of the United States of America , 116 (25) pp. 12301-12310. 10.1073/pnas.1818206116. Green open access
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Pereira, R; Gendron, T; Sanghera, C; Greenwood, HE; Newcombe, J; McCormick, P; Sander, K; ... Witney, TH; + view all (2019) Mapping Aldehyde Dehydrogenase 1A1 Activity using an [¹⁸F]Substrate-based Approach. Chemistry & A European Journal , 25 (9) pp. 2345-2351. 10.1002/chem.201805473. Green open access
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Phillips, I; Shephard, EA; (2019) Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and disease. Xenobiotica 10.1080/00498254.2019.1643515. (In press).

Pinheiro, VB; (2019) Engineering-driven biological insights into DNA polymerase mechanism. Current Opinion in Biotechnology , 60 pp. 9-16. 10.1016/j.copbio.2018.11.008.

Potterton, A; Husseini, FS; Southey, MW; Bodkin, MJ; Heifetz, A; Coveney, PV; Townsend-Nicholson, A; (2019) Ensemble-Based Steered Molecular Dynamics Predicts Relative Residence Time of A2A Receptor Binders. Journal of Chemical Theory and Computation 10.1021/acs.jctc.8b01270. (In press).

Pritchard, RB; Hansen, DF; (2019) Characterising side chains in large proteins by protonless 13C-detected NMR spectroscopy. Nature Communications , 10 (1) , Article 1747. 10.1038/s41467-019-09743-4. Green open access
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R

Renders, M; Dumbre, S; Abramov, M; Kestemont, D; Margamuljana, L; Largy, E; Cozens, C; ... Herdewijn, P; + view all (2019) Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases. Nucleic Acids Research 10.1093/nar/gkz008. (In press). Green open access
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Rich, P; (2019) Cytochrome c oxidase: oxygen consumption, energy conservation and control. In: Nixon, P and Ruban, A and Barber, J, (eds.) Oxygen Production And Reduction In Artificial And Natural Systems. (pp. 135-145). World Scientific: Singapore.

S

Scheibenreif, L; Littmann, M; Orengo, C; Rost, B; (2019) FunFam protein families improve residue level molecular function prediction. BMC Bioinformatics , 20 (1) , Article 400. 10.1186/s12859-019-2988-x. Green open access
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Selvarajah, B; Azuelos, I; Platé, M; Guillotin, D; Forty, EJ; Contento, G; Woodcock, HV; ... Chambers, RC; + view all (2019) mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis. Science Signaling , 12 (582) 10.1126/scisignal.aav3048. Green open access
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Sillitoe, I; Dawson, N; Lewis, TE; Das, S; Lees, JG; Ashford, P; Tolulope, A; ... Orengo, CA; + view all (2019) CATH: expanding the horizons of structure-based functional annotations for genome sequences. Nucleic Acids Research , 47 (D1) D280-D284. 10.1093/nar/gky1097. Green open access
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Srai, S; (2019) Iron uptake by ZIP8 and ZIP14 in human proximal tubular epithelial cells. BioMetals , 32 (2) pp. 211-226. 10.1007/s10534-019-00183-7. Green open access
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T

Terry, C; Harniman, RL; Sells, J; Wenborn, A; Joiner, S; Saibil, HR; Miles, MJ; ... Wadsworth, JDF; + view all (2019) Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro. Scientific Reports , 9 , Article 376. 10.1038/s41598-018-36700-w. Green open access
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Tosi, T; Hoshiga, F; Millership, C; Singh, R; Eldrid, C; Patin, D; Mengin-Lecreulx, D; ... Gründling, A; + view all (2019) Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM. PLoS Pathogens , 15 (1) , Article e1007537. 10.1371/journal.ppat.1007537. (In press). Green open access
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Townsend-Nicholson, A; (2019) Computational Prediction of GPCR Oligomerisation. Current Opinion in Structural Biology , 55 pp. 178-184. 10.1016/j.sbi.2019.04.005.

Trnka, MJ; Pellarin, R; Robinson, PJ; (2019) Role of integrative structural biology in understanding transcriptional initiation. Methods 10.1016/j.ymeth.2019.03.009. (In press). Green open access
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Tyzack, JD; Furnham, N; Sillitoe, I; Orengo, CM; Thornton, JM; (2019) Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function. Methods in Molecular Biology , 1851 pp. 263-275. 10.1007/978-1-4939-8736-8_14.

V

Vanmeert, M; Razzokov, J; Mirza, MU; D Weeks, S; Schepers, G; Bogaerts, A; Rozenski, J; ... Lescrinier, E; + view all (2019) Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins. Nucleic Acids Research , 47 (13) pp. 7130-7142. 10.1093/nar/gkz551. Green open access
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Vecchioni, S; Capece, MC; Toomey, E; Nguyen, L; Ray, A; Greenberg, A; Fujishima, K; ... Rothschild, L; + view all (2019) Construction and characterization of metal ion-containing DNA nanowires for synthetic biology and nanotechnology. Scientific Reports , 9 , Article 6942. 10.1038/s41598-019-43316-1. Green open access
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von Loeffelholz, O; Pena, A; Drummond, DR; Cross, R; Moores, CA; (2019) Cryo-EM Structure (4.5-angstrom) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance. Journal of Molecular Biology , 431 (4) pp. 864-872. 10.1016/j.jmb.2019.01.011. Green open access
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W

Waksman, G; (2019) From conjugation to T4S systems in Gram-negative bacteria: a mechanistic biology perspective. EMBO Reports , 2018 , Article e47012. 10.15252/embr.201847012. Green open access
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Waksman, G; Redzej, A; Costa, T; (2019) The high resolution cryo electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation. Nature Communications (In press).

Waudby, CA; Dobson, CM; Christodoulou, J; (2019) Nature and Regulation of Protein Folding on the Ribosome. Trends in Biochemical Sciences 10.1016/j.tibs.2019.06.008. (In press). Green open access
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Waudby, CA; Frenkiel, T; Christodoulou, J; (2019) Cross‐peaks in simple 2D NMR experiments from chemical exchange of transverse magnetization. Angewandte Chemie International Edition 10.1002/anie.201903245. (In press).

This list was generated on Sun Aug 18 06:45:00 2019 BST.