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Number of items: 110.

A

Abedini, A; Cao, P; Plesner, A; Zhang, J; He, M; Derk, J; Patil, SA; ... Schmidt, AM; + view all (2018) RAGE binds preamyloid IAPP intermediates and mediates pancreatic beta cell proteotoxicity. Journal of Clinical Investigation , 128 (2) pp. 682-698. 10.1172/JCI85210. Green open access
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Ahmed, AA; Luo, CJ; Perez-Garrido, S; Browse, CR; Thrasivoulou, C; Stoyanov, SD; Smoukov, SK; (2018) 3D cancer cell culture in high‐yield multi‐scale scaffolds by shear spinning. Biotechnology Progress 10.1002/btpr.2750. (In press).

Al-Olabi, L; Polubothu, S; Dowsett, K; Andrews, KA; Stadnik, P; Joseph, AP; Knox, R; ... Kinsler, VA; + view all (2018) Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy. The Journal of Clinical Investigation , 128 (4) pp. 1496-1508. 10.1172/JCI98589. Green open access
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Ameh, EM; Tyrrel, S; Harris, J; Ignatiou, A; Orlova, E; Nocker, A; (2018) The absence or presence of a lytic coliphage affects the response of Escherichia coli to heat, chlorine, or UV exposure. Folia Microbiologica , 63 (5) pp. 599-606. 10.1007/s12223-018-0600-9. Green open access
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Argemi, X; Matelska, D; Ginalski, K; Riegel, P; Hansmann, Y; Bloom, J; Pestel-Caron, M; ... Prevost, G; + view all (2018) Comparative genomic analysis of Staphylococcus lugdunensis shows a closed pan-genome and multiple barriers to horizontal gene transfer. BMC Genomics , 19 , Article 621. 10.1186/s12864-018-4978-1. Green open access
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Atherton, J; Stouffer, M; Francis, F; Moores, CA; (2018) Microtubule architecture in vitro and in cells revealed by cryo-electron tomography. Acta Crystallographica Section D - Structural Biology , D74 pp. 572-584. 10.1107/S2059798318001948. Green open access
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Augustin, H; McGourty, K; Allen, MJ; Adcott, J; Wong, CT; Boucrot, E; Partridge, L; (2018) Impact of insulin signaling and proteasomal activity on physiological 2 output of a neuronal circuit in aging D. melanogaster. Neurobiology of Aging , 66 pp. 149-157. 10.1016/j.neurobiolaging.2018.02.027. Green open access
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B

Badilla, C; Osborne, TH; Cole, A; Watson, C; Djordjevic, S; Santini, JM; (2018) A new family of periplasmic-binding proteins that sense arsenic oxyanions. Scientific Reports , 8 , Article 6282. 10.1038/s41598-018-24591-w. Green open access
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Basu, S; Fowler, B; Kerur, N; Arnvig, KB; Rao, NA; (2018) NLRP3 inflammasome activation by mycobacterial ESAT-6 and dsRNA in intraocular tuberculosis. Microbial Pathogenesis , 114 pp. 219-224. 10.1016/j.micpath.2017.11.044. Green open access
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Baum, J; Raleigh, D; (2018) Protein Aggregation. [Editorial comment]. Protein Science , 27 (7) pp. 1149-1150. 10.1002/pro.3446. Green open access
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Bernardes Pinheiro, VB; (2018) E. coli surface display of streptavidin for directed evolution of an allylic deallylase. Chemical Science , 9 (24) pp. 5383-5388. 10.1039/C8SC00484F. Green open access
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Bernardes Pinheiro, VB; (2018) Phosphonomethyl Oligonucleotides as Backbone Modified Artificial Genetic Polymers. Journal of the American Chemical Society 10.1021/jacs.8b03447. (In press). Green open access
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Blombach, F; Ausiannikava, D; Figueiredo, AM; Soloviev, Z; Prentice, T; Zhang, M; Zhou, N; ... Werner, F; + view all (2018) Structural and functional adaptation of Haloferax volcanii TFEα/β. Nucleic Acids Research , 46 (5) pp. 2308-2320. 10.1093/nar/gkx1302. Green open access
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Bordin, N; Carlos Gonzalez-Sanchez, J; Devos, DP; (2018) PVCbase: an integrated web resource for the PVC bacterial proteomes. Database , 2018 , Article bay042. 10.1093/database/bay042. Green open access
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Bowers, K; Srai, S; (2018) The trafficking of metal ion transporters of the Zrt‐ and Irt‐like protein family. Traffic , 19 (11) pp. 813-822. 10.1111/tra.12602. Green open access
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Brennan, AJ; Law, RHP; Conroy, PJ; Noori, T; Lukoyanova, N; Saibil, H; Yagita, H; ... Voskoboinik, I; + view all (2018) Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death & Differentiation , 25 (8) pp. 1517-1529. 10.1038/s41418-018-0057-z. Green open access
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Briggs, LC; Chan, AWE; Davis, CA; Whitelock, N; Hotiana, HA; Baratchian, M; Bagnéris, C; ... Barrett, TE; + view all (2018) IKKγ mimetic peptides block the resistance to apoptosis associated with KSHV infection. Journal of Virology , 92 (3) 10.1128/JVI.01170-17. Green open access
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Bullock, JMA; Sen, N; Thalassinos, K; Topf, M; (2018) Modeling Protein Complexes Using Restraints from Crosslinking Mass Spectrometry. Structure , 26 (7) pp. 1015-1024. 10.1016/j.str.2018.04.016. Green open access
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Bullock, JMA; Thalassinos, K; Topf, M; (2018) Jwalk and MNXL Web Server: Model Validation using Restraints from Crosslinking Mass Spectrometry. Bioinformatics , 34 (20) pp. 3584-3585. 10.1093/bioinformatics/bty366. Green open access
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Bunney, TD; Inglis, AJ; Sanfelice, D; Farrell, B; Kerr, CJ; Thompson, GS; Masson, GR; ... Katan, M; + view all (2018) Disease variants of FGFR3 reveal molecular basis for the recognition and new roles for Cdc37 in Hsp90 chaperone system. Structure , 26 (3) 446-458.e8. 10.1016/j.str.2018.01.016. Gold open access
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C

Chan Wah Hak, L; Khan, S; Di Meglio, I; Law, A-L; Häsler, SL-A; Quintaneiro, LM; Ferreira, APA; ... Boucrot, E; + view all (2018) FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis. Nature Cell Biology , 20 pp. 1023-1031. 10.1038/s41556-018-0146-8. Green open access
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Charoonnart, P; Purton, S; Saksmerprome, V; (2018) Applications of Microalgal Biotechnology for Disease Control in Aquaculture. Biology , 7 (2) , Article 24. 10.3390/biology7020024. Green open access
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Chen, J-B; Ramadani, F; Pang, MOY; Beavil, RL; Holdom, MD; Mitropoulou, AN; Beavil, AJ; ... Davies, AM; + view all (2018) Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody. Scientific Reports , 8 , Article 11548. 10.1038/s41598-018-29664-4. Green open access
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Cheung, ACM; Díaz-Santín, LM; (2018) Share and share alike: the role of Tra1 from the SAGA and NuA4 coactivator complexes. Transcription pp. 1-7. 10.1080/21541264.2018.1530936. Green open access
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Cozens, C; Pinheiro, VB; (2018) Darwin Assembly: fast, efficient, multi-site bespoke mutagenesis. Nucleic Acids Research , 46 (8) e51. 10.1093/nar/gky067. Green open access
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Cozens, C; Pinheiro, VB; (2018) XNA Synthesis and Reverse Transcription by Engineered Thermophilic Polymerases. Current Protocols in Chemical Biology , 10 (3) , Article e47. 10.1002/cpch.47.

D

Das, S; Orengo, C; (2018) Choosing the Best Enzyme Complex Structure Made Easy. Structure , 26 (4) pp. 528-530. 10.1016/j.str.2018.03.009. Green open access
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Davis, AG; Meintjes, G; Wilkinson, R; (2018) Treatment of Tuberculous Meningitis and Its Complications in Adults. Current Treatment Options in Neurology 10.1007/s11940-018-0490-9. (In press). Green open access
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Dyo, YM; Purton, S; (2018) The algal chloroplast as a synthetic biology platform for production of therapeutic proteins. Microbiology , 164 pp. 113-121. 10.1099/mic.0.000599. Green open access
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E

Esland, L; Larrea-Alvarez, M; Purton, S; (2018) Selectable Markers and Reporter Genes for Engineering the Chloroplast of Chlamydomonas reinhardtii. Biology , 7 (4) 10.3390/biology7040046. Green open access
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F

Fedele, L; Newcombe, J; Topf, M; Gibb, A; Harvey, RJ; Smart, TG; (2018) Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties. Nature Communications , 9 , Article 957. 10.1038/s41467-018-02927-4. Green open access
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Ferdous, S; Martin, ACR; (2018) AbDb: Antibody structure database - A database of PDB derived antibody structures. Database : the Journal of Biological Databases and Curation 10.1093/database/bay040. (In press). Green open access
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Ferreira, APA; Boucrot, E; (2018) Mechanisms of Carrier Formation during Clathrin-Independent Endocytosis. Trends in Cell Biology , 28 (3) pp. 188-200. 10.1016/j.tcb.2017.11.004. Green open access
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Ford, C; Nans, A; Boucrot, E; Hayward, RD; (2018) Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry. PLoS Pathogens , 14 (5) , Article e1007051. 10.1371/journal.ppat.1007051. Green open access
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Fouqueau, T; Blombach, F; Cackett, G; Carty, AE; Matelska, DM; Ofer, S; Pilotto, S; ... Werner, F; + view all (2018) The cutting edge of archaeal transcription. Emerging Topics in Life Sciences , 2 (4) pp. 517-533. 10.1042/ETLS20180014. Green open access
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G

Galan, JE; Waksman, G; (2018) Protein-Injection Machines in Bacteria. [Review]. Cell , 172 (6) pp. 1306-1318. 10.1016/j.cell.2018.01.034. Green open access
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Gallagher, C; Ramos, A; (2018) Joining the dots: protein-RNA interactions mediating local mRNA translation in neurons. FEBS Letters , 592 (17) pp. 2932-2947. 10.1002/1873-3468.13121. Green open access
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Glasser, NR; Oyala, PH; Osborne, TH; Santini, JM; Newman, DK; (2018) Structural and mechanistic analysis of the arsenate respiratory reductase provides insight into environmental arsenic transformations. Proceedings of the National Academy of Sciences of the United States of America , 115 (37) E8614-E8623. 10.1073/pnas.1807984115. Green open access
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Gopalan, AB; Hansen, DF; Vallurupalli, P; (2018) CPMG Experiments for Protein Minor Conformer Structure Determination. Methods in Molecular Biology , 1688 pp. 223-242. 10.1007/978-1-4939-7386-6_11. Green open access
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Goswami, P; Abid Ali, F; Douglas, ME; Locke, J; Purkiss, A; Janska, A; Eickhoff, P; ... Costa, A; + view all (2018) Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome. Nature Communications , 9 , Article 5061. 10.1038/s41467-018-07417-1. Green open access
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Gout, I; (2018) Coenzyme A, protein CoAlation and redox regulation in mammalian cells. Biochemical Society Transactions , 46 (3) pp. 721-728. 10.1042/BST20170506. Green open access
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Grohmann, E; Christie, PJ; Waksman, G; Backert, S; (2018) Type IV secretion in Gram-negative and Gram-positive bacteria. Molecular Microbiology , 107 (4) pp. 455-471. 10.1111/mmi.13896. Green open access
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H

Hinze, C; Boucrot, E; (2018) Endocytosis in proliferating, quiescent and terminally differentiated cells. Journal of Cell Science , 131 (23) 10.1242/jcs.216804.

Hinze, C; Boucrot, E; (2018) Local actin polymerization during endocytic carrier formation. Biochemical Society Transactions , 46 (3) pp. 565-576. 10.1042/BST20170355. Green open access
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Hobor, F; Dallmann, A; Ball, NJ; Cicchini, C; Battistelli, C; Ogrodowicz, RW; Christodoulou, E; ... Ramos, A; + view all (2018) A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nature Communications , 9 , Article 831. 10.1038/s41467-018-03182-3. Green open access
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Hutchings, J; Stancheva, V; Miller, EA; Zanetti, G; (2018) Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape. Nature Communications , 9 , Article 4154. 10.1038/s41467-018-06577-4. Green open access
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Hutchings, J; Zanetti, G; (2018) Fine details in complex environments: the power of cryo-electron tomography. Biochemical Society Transactions , 46 pp. 807-816. 10.1042/BST20170351. Green open access
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J

Jabgunde, AM; Jaziri, F; Bande, O; Froeyen, M; Abramov, M; Hoai, N; Schepers, G; ... Herdewijn, P; + view all (2018) Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo. Chemistry - A European Journal , 24 (48) pp. 12695-12707. 10.1002/chem.201802304. Green open access
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Jonik-Nowak, B; Menneteau, T; Fesquet, D; Baldin, V; Bonne-Andrea, C; Méchali, F; Fabre, B; ... Coux, O; + view all (2018) PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ. Proceedings of the National Academy of Sciences of the United States of America , 115 (28) E6477-E6486. 10.1073/pnas.1722299115. Green open access
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K

Kestemont, D; Renders, M; Leonczak, P; Abramov, M; Schepers, G; Pinheiro, VB; Rozenski, J; (2018) XNA ligation using T4 DNA ligase in crowding conditions. Chemical Communications , 54 (49) pp. 6408-6411. 10.1039/C8CC02414F. Green open access
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Koss, H; Bunney, TD; Esposito, D; Martins, M; Katan, M; Driscoll, PC; (2018) Dynamic Allostery in PLC gamma 1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR. Biophysical Journal , 115 (1) pp. 31-45. 10.1016/j.bpj.2018.05.031. Green open access
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Kutner, J; Shabalin, IG; Matelska, D; Handing, KB; Gasiorowska, O; Sroka, P; Gorna, MW; ... Minor, W; + view all (2018) Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry , 57 (6) pp. 963-977. 10.1021/acs.biochem.7b01137. Green open access
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L

Lesjak, M; Balesaria, S; Skinner, V; Debnam, ES; Srai, SKS; (2018) Quercetin inhibits intestinal non-haem iron absorption by regulating iron metabolism genes in the tissues. European Journal of Nutrition 10.1007/s00394-018-1680-7. (In press). Green open access
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Lewis, TE; Sillitoe, I; Lees, JG; (2018) cath-resolve-hits: a new tool that resolves domain matches suspiciously quickly. Bioinformatics , 35 (10) pp. 1766-1767. 10.1093/bioinformatics/bty863. Green open access
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Lizzul, AM; Lekuona-Amundarain, A; Purton, S; Campos, LC; (2018) Characterization of Chlorella sorokiniana, UTEX 1230. Biology , 7 (2) , Article 25. 10.3390/biology7020025. Green open access
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Lopez-Fontal, E; Grochmal, A; Foran, T; Milanesi, L; Tomas, S; (2018) Ship in a bottle: confinement-promoted self-assembly. Chemical Science , 9 (7) pp. 1760-1768. 10.1039/c7sc04553k. Green open access
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Lowe, AR; Perez-Riba, A; Itzhaki, LS; Main, ER; (2018) PyFolding: Open-Source Graphing, Simulation, and Analysis of the Biophysical Properties of Proteins. Biophysical Journal , 114 (3) pp. 516-521. 10.1016/j.bpj.2017.11.3779. Green open access
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M

Manka, SW; Moores, CA; (2018) Microtubule structure by cryo-EM: snapshots of dynamic instability. Essays in Biochemistry , 62 (6) pp. 737-751. 10.1042/EBC20180031. Green open access
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Manka, SW; Moores, CA; (2018) The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability. Nature Structural & Molecular Biology , 25 (7) pp. 607-615. 10.1038/s41594-018-0087-8. Green open access
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Maréchal, A; Hartley, AM; Warelow, TP; Meunier, B; Rich, PR; (2018) Comparison of redox and ligand binding behaviour of yeast and bovine cytochrome c oxidases using FTIR spectroscopy. Biochimica et Biophysica Acta (BBA) - Bioenergetics , 1859 (9) pp. 705-711. 10.1016/j.bbabio.2018.05.018. Green open access
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Matelska, D; Shabalin, IG; Jabłońska, J; Domagalski, MJ; Kutner, J; Ginalski, K; Minor, W; (2018) Classification, substrate specificity and structural features of D-2-hydroxyacid dehydrogenases: 2HADH knowledgebase. BMC Evolutionary Biology , 18 , Article 199. 10.1186/s12862-018-1309-8. Green open access
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McTague, A; Nair, U; Malhotra, S; Meyer, E; Trump, N; Gazina, EV; Papandreou, A; ... Kurian, MA; + view all (2018) Clinical and molecular characterization of KCNT1-related severe early-onset epilepsy. Neurology , 90 (1) e55-e66. 10.1212/WNL.0000000000004762. Green open access
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Meir, A; Chetrit, D; Liu, L; Roy, C; Waksman, G; (2018) Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system. Nature Communications , 9 , Article 507. 10.1038/s41467-017-02578-x. Green open access
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Menny, A; Serna, M; Boyd, CM; Gardner, S; Joseph, AP; Morgan, BP; Topf, M; ... Bubeck, D; + view all (2018) CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nature Communications , 9 , Article 5316. 10.1038/s41467-018-07653-5. Green open access
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Mitchell, AL; Attwood, TK; Babbitt, PC; Blum, M; Bork, P; Bridge, A; Brown, SD; ... Finn, RD; + view all (2018) InterPro in 2019: improving coverage, classification and access to protein sequence annotations. Nucleic Acids Research 10.1093/nar/gky1100. Green open access
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Mitropoulou, AN; Bowen, H; Dodev, TS; Davies, AM; Bax, HJ; Beavil, RL; Beavil, AJ; ... Sutton, BJ; + view all (2018) Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition. Proceedings of the National Academy of Sciences of the United States of America , 115 (37) e8707-e8716. 10.1073/pnas.1806840115. Green open access
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Mittal, A; Hobor, F; Zhang, Y; Martin, SR; Gamblin, SJ; Ramos, A; Wilson, JR; (2018) The structure of the RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sites. Nucleic Acids Research , 46 (7) pp. 3802-3812. 10.1093/nar/gky199. Green open access
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Mota, F; Fotinou, C; Rhana, R; Edith Chan, AW; Yelland, T; Arooz, MT; O'Leary, AP; ... Djordjevic, S; + view all (2018) Architecture and Hydration of the Arginine Binding Site of Neuropilin-1. The FEBS Journal , 285 (7) pp. 1290-1304. 10.1111/febs.14405. Green open access
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Moulin, M; Strohmeier, GA; Hirz, M; Thompson, KC; Rennie, AR; Campbell, RA; Pichler, H; ... Haertlein, M; + view all (2018) Perdeuteration of cholesterol for neutron scattering applications using recombinant Pichia pastoris. Chemistry and Physics of Lipids , 212 pp. 80-87. 10.1016/j.chemphyslip.2018.01.006. Green open access
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N

Nagarajan, S; Xiao, S; Raleigh, DP; Dyer, RB; (2018) Heterogeneity in the Folding of Villin Headpiece Subdomain HP36. Journal of Physical Chemistry B , 122 (49) pp. 11640-11648. 10.1021/acs.jpcb.8b07683. Green open access
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Natesh, R; Clare, DK; Farr, GW; Horwich, AL; Saibil, HR; (2018) A two-domain folding intermediate of RuBisCO in complex with the GroEL chaperonin. International Journal of Biological Macromolecules , 118 (Part A) pp. 671-675. 10.1016/j.ijbiomac.2018.06.120. Green open access
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Neves, JF; Doffinger, R; Barcena-Morales, G; Martins, C; Papapietro, O; Plagnol, V; Curtis, J; ... Nejentsev, S; + view all (2018) Novel PLCG2 Mutation in a Patient With APLAID and Cutis Laxa. Frontiers in Immunology , 9 , Article 2863. 10.3389/fimmu.2018.02863. Green open access
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Newcombe, J; Chatzidaki, A; Sheppard, TD; Topf, M; Millar, NS; (2018) Diversity of nicotinic acetylcholine receptor positive allosteric modulators revealed by mutagenesis and a revised structural model. Molecular Pharmacology , 93 (2) pp. 128-140. 10.1124/mol.117.110551. Green open access
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Nigris, S; Baldan, E; Tondello, A; Zanella, F; Vitulo, N; Favaro, G; Guidolin, V; ... Baldan, B; + view all (2018) Biocontrol traits of Bacillus licheniformis GL174, a culturable endophyte of Vitis vinifera cv. Glera. BMC Microbiology , 18 , Article 133. 10.1186/s12866-018-1306-5. Green open access
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Northey, T; Baresic, A; Martin, ACR; (2018) IntPred: a structure-based predictor of protein-protein interaction sites. Bioinformatics , 34 (2) pp. 223-229. 10.1093/bioinformatics/btx585. Green open access
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Norvaisas, P; Cabreiro, F; (2018) Pharmacology in the age of the holobiont. Current Opinion in Systems Biology , 10 pp. 34-42. 10.1016/j.coisb.2018.05.006. Green open access
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O

Osborne, A; Breno, M; Ghiringhelli Borsa, N; Bu, F; Frémeaux-Bacchi, V; Gale, D; van den Heuvel, LP; ... Perkins, SJ; + view all (2018) Statistical validation of rare complement variants provides insights on the molecular basis of atypical haemolytic uraemic syndrome and C3 glomerulopathy. Journal of Immunology , 200 (7) pp. 2464-2478. 10.4049/jimmunol.1701695.

Osborne, AJ; Nan, R; Miller, A; Bhatt, JS; Gor, J; Perkins, SJ; (2018) Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces. Journal of Biological Chemistry , 293 , Article 44. 10.1074/jbc.RA118.004767. Green open access
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Osborne, T; Ward, SA; Ahmed, KM; Santini, JM; (2018) Reservoirs of faecal indicator bacteria in well-head hand pumps in Bangladesh. Journal of Water and Health , 16 (3) pp. 487-490. 10.2166/wh.2018.042. Green open access
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P

Perez-Riba, A; Lowe, AR; Main, E; Itzhaki, L; (2018) Context-Dependent Energetics of Loop Extensions in a Family of Tandem-Repeat Proteins. Biophysical Journal , 114 (11) pp. 2552-2562. 10.1016/j.bpj.2018.03.038. Green open access
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Peskett, TR; Rau, F; O'Driscoll, J; Patani, R; Lowe, AR; Saibil, HR; (2018) A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation. Molecular Cell , 70 (4) 588-601.e6. 10.1016/j.molcel.2018.04.007. Green open access
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Phillip, IR; Shephard, EA; Stein, JL; Stein, GS; (2018) Role of nonhistone chromosomal proteins in selective gene expression. In: Eukaryotic Gene Regulation. (pp. 113-178).

Potterton, A; Heifetz, A; Townsend-Nicholson, A; (2018) Synergistic Use of GPCR Modeling and SDM Experiments to Understand Ligand Binding. Methods in Molecular Biology , 1705 pp. 335-343. 10.1007/978-1-4939-7465-8_15. Green open access
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Powell, J; Mota, F; Steadman, D; Soudy, C; Miyauchi, JT; Crosby, S; Jarvis, A; ... Selwood, DL; + view all (2018) Small molecule neuropilin-1 antagonists combine anti-angiogenic and anti-tumour activity with immune modulation through reduction of transforming growth factor beta (TGFβ) production in regulatory T-cells. Journal of Medicinal Chemistry , 61 (9) pp. 4135-4154. 10.1021/acs.jmedchem.8b00210. Green open access
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Prevost, MS; Waksman, G; (2018) X‐ray crystal structures of the type IVb secretion system DotB ATPases. Protein Science , 27 (8) pp. 1464-1475. 10.1002/pro.3439. Green open access
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R

Ruiz-Pérez, L; Hurley, C; Tomás, S; Battaglia, G; (2018) Separating Extreme pH Gradients Using Amphiphilic Copolymer Membranes. ChemPhysChem , 19 (16) pp. 1987-1989. 10.1002/cphc.201800187. Green open access
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Rust, A; Shah, S; Hautbergue, GM; Davletov, B; (2018) Burkholderia Lethal Factor 1, a Novel Anti-Cancer Toxin, Demonstrates Selective Cytotoxicity in MYCN-Amplified Neuroblastoma Cells. Toxins , 10 (7) , Article 261. 10.3390/toxins10070261. Green open access
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S

Sanfelice, D; Koss, H; Bunney, TD; Thompson, GS; Farrell, B; Katan, M; Breeze, AL; (2018) NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074. Biomolecular NMR Assignments 10.1007/s12104-018-9814-7. Green open access
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Santos, AJM; Boucrot, E; (2018) Probing Endocytosis During the Cell Cycle with Minimal Experimental Perturbation. Methods in Molecular Biology , 1847 pp. 23-35. 10.1007/978-1-4939-8719-1_3. Green open access
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Schwenk, S; Arnvig, KB; (2018) Regulatory RNA in Mycobacterium tuberculosis, back to basics. Pathogens and Disease , 76 (4) , Article fty035. 10.1093/femspd/fty035. (In press). Green open access
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Schwenk, S; Moores, A; Nobeli, I; McHugh, TD; Arnvig, KB; (2018) Cell-wall synthesis and ribosome maturation are co-regulated by an RNA switch in Mycobacterium tuberculosis. Nucleic Acids Research , 46 (11) pp. 5837-5849. 10.1093/nar/gky226. Green open access
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Sgro, GG; Costa, TRD; Cenens, W; Souza, DP; Cassago, A; de Oliveira, LC; Salinas, RK; ... Waksman, G; + view all (2018) Cryo-EM structure of the bacteria-killing type IV secretion system core complex from Xanthomonas citri. Nature Microbiology , 3 (12) pp. 1429-1440. 10.1038/s41564-018-0262-z. Green open access
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Sivalingam, GN; Cryar, A; Williams, MA; Gooptu, B; Thalassinos, K; (2018) Deconvolution of ion mobility mass spectrometry arrival time distributions using a genetic algorithm approach: Application to α1-antitrypsin peptide binding. International Journal of Mass Spectrometry , 426 pp. 29-37. 10.1016/j.ijms.2018.01.008. Green open access
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Smelt, CLC; Sanders, VR; Newcombe, J; Burt, RP; Sheppard, TD; Topf, M; Millar, NS; (2018) Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor. Neuropharmacology , 139 pp. 194-204. 10.1016/j.neuropharm.2018.07.009. Green open access
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Stenzoski, NE; Luang, B; Holehouse, AS; Raleigh, DP; (2018) The Unfolded State of the C-Terminal Domain of L9 Expands at Low but Not at Elevated Temperatures. Biophysical Journal , 115 (4) pp. 655-663. 10.1016/j.bpj.2018.07.013. Green open access
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Thomas, JA; Tan, MSY; Bisson, C; Borg, A; Umrekar, TR; Hackett, F; Hale, VL; ... Blackman, MJ; + view all (2018) A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells. Nature Microbiology , 3 (4) pp. 447-455. 10.1038/s41564-018-0111-0. Green open access
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Torres, LL; Pinheiro, VB; (2018) Xenobiotic Nucleic Acid (XNA) Synthesis by Phi29 DNA Polymerase. Current Protocols in Chemical Biology , 10 (2) , Article e41. 10.1002/cpch.41. Green open access
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Townsend-Nicholson, A; Jayasinghe, SN; (2018) Cell Electrospinning and Technology Transfer from Lab to Market Scale. In: Kny, E and Ghosal, K and Thomas, S, (eds.) Electrospinning: From Basic Research to Commercialization. (pp. 79-94). Royal Society of Chemistry: London, UK.

Trokter, M; Waksman, G; (2018) Translocation through the conjugative Type 4 secretion system requires unfolding of its protein substrate. Journal of Bacteriology , 200 (6) , Article e00615-17. 10.1128/JB.00615-17. Green open access
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Tsuchiya, Y; Zhyvoloup, A; Bakovic, J; Thomas, N; Yi Kun Yu, B; Das, S; Orengo, C; ... Gout, I; + view all (2018) Protein CoAlation and antioxidant function of Coenzyme A in prokaryotic cells. Biochemical Journal , 475 (11) pp. 1909-1937. 10.1042/BCJ20180043. Green open access
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Tweedy, JG; Escriva, E; Topf, M; Gompels, UA; (2018) Analyses of Tissue Culture Adaptation of Human Herpesvirus-6A by Whole Genome Deep Sequencing Redefines the Reference Sequence and Identifies Virus Entry Complex Changes. Viruses , 10 (1) , Article 16. 10.3390/v10010016. Green open access
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Varshavi, D; Scott, F; Varshavi, D; Veeravalli, SK; Phillips, I; Veselkov, K; Strittmatter, N; ... Everett, JR; + view all (2018) Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice. Frontiers in Molecular Biosciences , 5 , Article 28. 10.3389/fmolb.2018.00028. Green open access
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Veeravalli, S; Karu, K; Scott, F; Fennema, D; Phillips, IR; Shephard, EA; (2018) Effect of Flavin-Containing Monooxygenase Genotype, Mouse Strain, and Gender on Trimethylamine N-oxide Production, Plasma Cholesterol Concentration, and an Index of Atherosclerosis. Drug Metabolism and Disposition , 46 (1) pp. 20-25. 10.1124/dmd.117.077636. Green open access
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van Raaij, S; van Swelm, R; Bouman, K; Cliteur, M; van den Heuvel, M; Pertijs, J; Patel, D; ... Swinkels, D; + view all (2018) Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease. Scientific Reports , 8 , Article 9353. 10.1038/s41598-018-27107-8. Green open access
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van Raaij, S; van Swelm, R; Bouman, K; Cliteur, M; van den Heuvel, MC; Pertijs, J; Patel, D; ... Swinkels, D; + view all (2018) Publisher Correction: Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease). [Corrigendum]. Scientific Reports , 8 , Article 13390. 10.1038/s41598-018-31457-8. Green open access
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Watson, MD; Monroe, J; Raleigh, DP; (2018) Size-Dependent Relationships between Protein Stability and Thermal Unfolding Temperature Have Important Implications for Analysis of Protein Energetics and High-Throughput Assays of Protein-Ligand Interactions. Journal of Physical Chemistry B , 122 (21) pp. 5278-5285. 10.1021/acs.jpcb.7b05684. Green open access
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Waudby, CA; Wlodarski, T; Karyadi, M-E; Cassaignau, AME; Chan, SHS; Wentink, AS; Schmidt-Engler, JM; ... Christodoulou, J; + view all (2018) Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis. Proceedings of the National Academy of Sciences , 115 (39) pp. 9744-9749. 10.1073/pnas.1716252115. Green open access
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Zhang, W; Lukoynova, N; Miah, S; Lucas, J; Vaughan, CK; (2018) Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10. Cell Reports , 24 (3) pp. 744-754. 10.1016/j.celrep.2018.06.068. Green open access
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Zhang, X; London, E; Raleigh, DP; (2018) Sterol Structure Strongly Modulates Membrane-Islet Amyloid Polypeptide Interactions. Biochemistry , 57 (12) pp. 1868-1879. 10.1021/acs.biochem.7b01190. Green open access
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This list was generated on Sun Aug 25 06:38:35 2019 BST.