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Number of items: 66.


Allenmark, S; Grainger, RS; Olsson, S; Patel, B; (2011) Resolution and Determination of the Absolute Configuration of the Enantiomers of a trans-α-Disulfoxide. European Journal of Organic Chemistry , 2011 (22) pp. 4089-4092. 10.1002/ejoc.201100419.

Andrade-Cetto, A; Heinrich, M; (2011) From the field into the lab: useful approaches to selecting species based on local knowledge. FRONTIERS IN PHARMACOLOGY , 2 (ARTN 20) 10.3389/fphar.2011.00020. Gold open access


Brickley, K; Stephenson, FA; (2011) Trafficking Kinesin Protein (TRAK)-mediated Transport of Mitochondria in Axons of Hippocampal Neurons. JOURNAL OF BIOLOGICAL CHEMISTRY , 286 (20) pp. 18079-18092. 10.1074/jbc.M111.236018. Gold open access

Brucoli, F; Hawkins, RM; James, CH; Wells, G; Jenkins, TC; Ellis, T; Hartley, JA; ... Thurston, DE; + view all (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. BIOORG MED CHEM LETT , 21 (12) 3780 - 3783. 10.1016/j.bmcl.2011.04.054.

Buanz, ABM; Parkinson, GN; Gaisford, S; (2011) Characterization of Carbamazepine-Nicatinamide Cocrystal Polymorphs with Rapid Heating DSC and XRPD. CRYSTAL GROWTH & DESIGN , 11 (4) pp. 1177-1181. 10.1021/cg101377u.


Campbelll, NH; Karim, NHA; Parkinson, GN; Vilar, R; Neidie, S; (2011) The first crystal structure of a telomeric quadruplex DNA with a metal containing ligand. CANCER RESEARCH , 71 10.1158/1538-7445.AM2011-2326.

Casselman, I; Heinrich, M; (2011) Novel use patterns of Salvia divinorum: Unobtrusive observation using YouTube (TM). JOURNAL OF ETHNOPHARMACOLOGY , 138 (3) pp. 662-667. 10.1016/j.jep.2011.07.065.

Collie, GW; Parkinson, GN; (2011) The application of DNA and RNA G-quadruplexes to therapeutic medicines. CHEMICAL SOCIETY REVIEWS , 40 (12) pp. 5867-5892. 10.1039/c1cs15067g.

Collie, GW; Sparapani, S; Parkinson, GN; Neidle, S; (2011) Structural Basis of Telomeric RNA Quadruplex-Acridine Ligand Recognition. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 133 (8) pp. 2721-2728. 10.1021/ja109767y.


Firdous, N; Gibbons, S; Modell, B; (2011) Falling prevalence of beta-thalassaemia and eradication of malaria in the Maldives. J Community Genet , 2 (3) pp. 173-189. 10.1007/s12687-011-0054-0.


Garvey, MI; Rahman, MM; Gibbons, S; Piddock, LJV; (2011) Medicinal plant extracts with efflux inhibitory activity against Gram-negative bacteria. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS , 37 (2) pp. 145-151. 10.1016/j.ijantimicag.2010.10.027.

Gibbons, S; (2011) Novel and Emerging Drugs: A Chemical Overview for the Toxicologist. CLINICAL TOXICOLOGY , 49 (3) p. 198.

Giovannini, P; Reyes-Garcia, V; Waldstein, A; Heinrich, M; (2011) Do pharmaceuticals displace local knowledge and use of medicinal plants? Estimates from a cross-sectional study in a rural indigenous community, Mexico. SOCIAL SCIENCE & MEDICINE , 72 (6) pp. 928-936. 10.1016/j.socscimed.2011.01.007.

Good, JAD; Skoufias, DA; Kozielski, F; (2011) Elucidating the functionality of kinesins: An overview of small molecule inhibitors. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY , 22 (9) pp. 935-945. 10.1016/j.semcdb.2011.09.023.

Grainger, RS; Patel, B; Kariuki, BM; Male, L; Spencer, N; (2011) Sulfur monoxide transfer from peri-substituted trisulfide-2-oxides to dienes: substituent effects, mechanistic studies and application in thiophene synthesis. J Am Chem Soc , 133 (15) pp. 5843-5852. 10.1021/ja108865w.

Guimaraes, AMR; Fuente, M; Stapleton, P; Ji, X; Oliyide, AO; Osbourn, A; Pan, Y; ... Yang, M; + view all (2011) Glycosylation enhances selectivity of novobiocin and alters antibacterial mechanism. In: (Proceedings) 241st National Meeting and Exposition of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Guimaraes, AMR; Fuente, MDL; Stapleton, PD; Ji, X; Oliyide, AO; Osbourn, A; Pandit, S; ... Yang, M; + view all (2011) Abstract: Glycosylation enhances selectivity of novobiocin and alters antibacterial mechanism. Abstract of Papers of the American Chemical Society , 241 (132-CARB)

Gunaratnam, M; de la Fuente, M; Hampel, SM; Todd, AK; Reszka, AP; Schaetzlein, A; Neidle, S; (2011) Targeting pancreatic cancer with a G-quadruplex ligand. BIOORGANIC & MEDICINAL CHEMISTRY , 19 (23) pp. 7151-7157. 10.1016/j.bmc.2011.09.055.

Guzman, JD; Wube, A; Evangelopoulos, D; Gupta, A; Hufner, A; Basavannacharya, C; Rahman, MM; ... Bhakta, S; + view all (2011) Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics. J ANTIMICROB CHEMOTH , 66 (8) 1766 - 1772. 10.1093/jac/dkr203.


Haider, S; Joseph, CG; Neidle, S; Fierke, CA; Fuchter, MJ; (2011) On the function of the internal cavity of histone deacetylase protein 8: R37 is a crucial residue for catalysis. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 21 (7) pp. 2129-2132. 10.1016/j.bmcl.2011.01.128.

Haider, SM; Autiero, I; Neidle, S; (2011) Surface area accessibility and the preferred topology of telomeric DNA quadruplex-ligand complexes. BIOCHIMIE , 93 (8) pp. 1275-1279. 10.1016/j.biochi.2011.05.014.

Haider, SM; Neidle, S; Parkinson, GN; (2011) A structural analysis of G-quadruplex/ligand interactions. BIOCHIMIE , 93 (8) pp. 1239-1251. 10.1016/j.biochi.2011.05.012.

Hancock, R; Bertrand, H; Naz, S; Tsujita, T; Hayes, J; Wells, G; (2011) Design, synthesis and biological evaluation of peptide inhibitors of the Keap1-Nrf2 protein-protein interaction. In: AMER ASSOC CANCER RESEARCH

Heinrich, M; (2011) From Belizean Dioscorea to Seaweeds - The Many Journeys of Prof. Gerry (Gerald) Blunden. NATURAL PRODUCT COMMUNICATIONS , 6 (5)

Heinrich, M; Dhanji, T; Casselman, I; (2011) Acai (Euterpe oleracea Mart.)-A phytochemical and pharmacological assessment of the species' health claims. PHYTOCHEMISTRY LETTERS , 4 (1) pp. 10-21. 10.1016/j.phytol.2010.11.005.

Hemingway, CJ; Munday, M; (2011) The lipid-lowering agent gemfibrozil inhibits fatty acid esterification. Journal of Pharmacy and Pharmacology , 50 (S9) 10.1111/j.2042-7158.1998.tb02408.x.


Ioannou, E; Quesada, A; Rahman, MM; Gibbons, S; Vagias, C; Roussis, V; (2011) Dolabellanes with Antibacterial Activity from the Brown Alga Dilophus spiralis. JOURNAL OF NATURAL PRODUCTS , 74 (2) pp. 213-222. 10.1021/np1006586.


Kaan, HYK; Hackney, DD; Kozielski, F; (2011) The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition. SCIENCE , 333 (6044) pp. 883-885. 10.1126/science.1204824.

Kaan, HYK; Weiss, J; Menger, D; Ulaganathan, V; Tkocz, K; Laggner, C; Popowycz, F; ... Kozielski, F; + view all (2011) Structure-Activity Relationship and Multidrug Resistance Study of New S-trityl-L-Cysteine Derivatives As Inhibitors of Eg5. JOURNAL OF MEDICINAL CHEMISTRY , 54 (6) pp. 1576-1586. 10.1021/jm100991m.

Koenig, J; Wyllie, S; Wells, G; Stevens, MF; Wyatt, PG; Fairlamb, AH; (2011) Antitumor Quinol PMX464 Is a Cytocidal Anti-trypanosomal Inhibitor Targeting Trypanothione Metabolism. JOURNAL OF BIOLOGICAL CHEMISTRY , 286 (10) pp. 8523-8533. 10.1074/jbc.M110.214833. Gold open access

Kozielski, F; Riaz, T; DeBonis, S; Koehler, CJ; Kroening, M; Panse, I; Strozynski, M; ... Thiede, B; + view all (2011) Proteome analysis of microtubule-associated proteins and their interacting partners from mammalian brain. AMINO ACIDS , 41 (2) pp. 363-385. 10.1007/s00726-010-0649-5.


Lardos, A; Prieto-Garcia, J; Heinrich, M; (2011) Resins and Gums in Historical Iatrosophia Texts from Cyprus - A Botanical and Medico-pharmacological Approach. Front Pharmacol , 2 , Article 32. 10.3389/fphar.2011.00032. Green open access

Lonetti, A; Szijgyarto, Z; Bosch, D; Loss, O; Azevedo, C; Saiardi, A; (2011) Identification of an Evolutionarily Conserved Family of Inorganic Polyphosphate Endopolyphosphatases. JOURNAL OF BIOLOGICAL CHEMISTRY , 286 (37) pp. 31966-31974. 10.1074/jbc.M111.266320.

Loss, O; Azevedo, C; Szijgyarto, Z; Bosch, D; Saiardi, A; (2011) Preparation of Quality Inositol Pyrophosphates. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (55) 10.3791/3027.

Lyngberg, L; Healy, J; Bartlett, W; Miller, S; Conway, SJ; Booth, IR; Rasmussen, T; (2011) KefF, the Regulatory Subunit of the Potassium Efflux System KefC, Shows Quinone Oxidoreductase Activity. JOURNAL OF BACTERIOLOGY , 193 (18) pp. 4925-4932. 10.1128/JB.05272-11.


Mamone, L; Di Venosa, G; Valla, JJ; Rodriguez, L; Gandara, L; Batlle, A; Heinrich, M; ... Casas, A; + view all (2011) CYTOTOXIC EFFECTS OF ARGENTINEAN PLANT EXTRACTS ON TUMOUR AND NORMAL CELL LINES. CELLULAR AND MOLECULAR BIOLOGY , 57 pp. 1487-1499. 10.1170/171.

Mazza, M; Gaisford, S; McCarthy, D; Schatzlein, AG; Uchegbu, IF; (2011) Fast gelation of self-assembling peptide nanofibres triggered by electromagnetic radiation heating. In: Laudon, M and Romanowicz, B, (eds.) (Proceedings) NSTI Nanotechnology Conference and Expo. (pp. pp. 650-653). CRC PRESS-TAYLOR & FRANCIS GROUP

Mazza, M; Schatzlein, A; Uchegbu, I; Gaisford, D; McCarthy, D; (2011) Fast gelation of self-assembling peptide nanofibres triggered by electromagnetic radiation heating. In: (Proceedings) NSTI Nanotechnology Conference and Expo. (pp. pp. 650-653).

Michl, J; Modarai, M; Edwards, S; Heinrich, M; (2011) Metabolomic Analysis of Ranunculus spp. as Potential Agents Involved in the Etiology of Equine Grass Sickness. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 59 (18) pp. 10388-10393. 10.1021/jf201430k.

Modarai, M; Silva, E; Suter, A; Heinrich, M; Kortenkamp, A; (2011) Safety of Herbal Medicinal Products: Echinacea and Selected Alkylamides Do Not Induce CYP3A4 mRNA Expression. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE pp. 1-7. 10.1093/ecam/nep174. Gold open access

Modarai, M; Suter, A; Kortenkamp, A; Heinrich, M; (2011) The interaction potential of herbal medicinal products: a luminescence-based screening platform assessing effects on cytochrome P450 and its use with devil's claw (Harpagophyti radix) preparations. JOURNAL OF PHARMACY AND PHARMACOLOGY , 63 (3) pp. 429-438. 10.1111/j.2042-7158.2010.01235.x.

Munday, M; Hemingway, CJ; (2011) The effect of the lipid-lowering agent gemfibrozil on glucose handling. Journal of Pharmacy and Pharmacology , 50 (S9) 10.1111/j.2042-7158.1998.tb02409.x.


Nielsen, MM; Suits, MDL; Yang, M; Barry, CS; Martinez-Fleites, C; Tailford, LE; Flint, JE; ... Davies, GJ; + view all (2011) Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase. JOURNAL OF BIOLOGICAL CHEMISTRY , 286 (17) pp. 15155-15164. 10.1074/jbc.M110.199844. Gold open access

Nordin, N; D'acquisto, F; Gibbons, S; Perrett, D; Mageed, RA; (2011) Potent anti-inflammatory compounds identified in Zingiber officinale Roscoe var. rubrum Theilade: Mechanisms of action in psoriasis. In: (Proceedings) 59th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research. (pp. pp. 1422-1423). GEORG THIEME VERLAG KG


Obolskiy, D; Pischel, I; Feistel, B; Glotov, N; Heinrich, M; (2011) Artemisia dracunculus L. (tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety. J Agric Food Chem , 59 (21) 11367 - 11384. 10.1021/jf202277w. Green open access


Parkinson, G; Wilson, C; Gunasekera, A; Ebright, YW; Ebright, RH; Berman, HM; (2011) Erratum: Structure of the CAP-DNA complex at 2.5 Å resolution: A complete picture of the protein-DNA Interface (Journal of Molecular Biology (1996) 260:3 (395-408)). Journal of Molecular Biology , 414 (1) 163-. 10.1016/j.jmb.2011.10.002.

Parkinson, GN; Gunaratnam, M; Li, XW; Collie, G; Reszka, AP; Todd, AR; Fletcher, JA; (2011) Down-regulating BCL-2 gene expression in a resistant GIST cell line by a RNA G-quadruplex interacting small molecule ligand. CANCER RESEARCH , 71 10.1158/1538-7445.AM2011-2310.

Patel, B; Carlisle, J; Bottle, SE; Hanson, GR; Kariuki, BM; Male, L; McMurtrie, JC; ... Grainger, RS; + view all (2011) In search of a new class of stable nitroxide: synthesis and reactivity of a peri-substituted N,N-bissulfonylhydroxylamine. Org Biomol Chem , 9 (7) pp. 2336-2344. 10.1039/c0ob00976h.

Patel, SM; de la Fuente, M; Ke, S; Guimaraes, AMR; Oliyide, AO; Ji, X; Stapleton, P; ... Yang, M; + view all (2011) High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity. CHEMICAL COMMUNICATIONS , 47 (38) pp. 10569-10571. 10.1039/c1cc13552j.

Pereira, I; Swain, A; Turton, J; Scudamore, CL; Maguire, D; Smyth, R; Freitas, S; ... York, M; + view all (2011) Urinary biomarkers of renal injury in the hexachloro-1:3-butadiene treated male Hanover Wistar rat; a dose-response study at low dose levels. TOXICOLOGY , 290 (2-3) pp. 138-139. 10.1016/j.tox.2011.09.066.

Peschel, W; Kump, A; Prieto, JM; (2011) Effects of 20-hydroxyecdysone, Leuzea carthamoides extracts, dexamethasone and their combinations on the NF-kappa B activation in HeLa cells. JOURNAL OF PHARMACY AND PHARMACOLOGY , 63 (11) pp. 1483-1495. 10.1111/j.2042-7158.2011.01349.x.

Petraccone, L; Fotticchia, I; Cummaro, A; Pagano, B; Ginnari-Satriani, L; Haider, S; Randazzo, A; ... Giancola, C; + view all (2011) The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: Biophysical and molecular modeling studies. BIOCHIMIE , 93 (8) pp. 1318-1327. 10.1016/j.biochi.2011.05.017.

Petralia, RS; Wang, YX; Hua, F; Yi, Z; Zhou, A; Ge, L; Stephenson, FA; (2011) ORGANIZATION OF NMDA RECEPTORS AT EXTRASYNAPTIC LOCATIONS (vol 167, pg 68, 2010). NEUROSCIENCE , 176 p. 472. 10.1016/j.neuroscience.2010.12.020.

Pozo, KBK; Stephenson, FA; (2011) N-acetylglucosamine transferase is an integral component of a kinesin-directed mitochondrial trafficking complex. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH , 1813 (1) pp. 269-281. 10.1016/j.bbamcr.2010.10.011.


Rahman, KM; James, CH; Bui, TTT; Drake, AF; Thurston, DE; (2011) Observation of a single-stranded DNA/pyrrolobenzodiazepine adduct. Journal of the American Chemical Society , 133 (48) 19376 - 19385. 10.1021/ja205395r.

Rahman, KM; James, CH; Thurston, DE; (2011) Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers. Nucleic Acids Research , 39 (13) 5800 - 5812. 10.1093/nar/gkr122. Green open access

Rahman, KM; James, CH; Thurston, DE; (2011) Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy. Org Biomol Chem , 9 (5) pp. 1632-1641. 10.1039/c0ob00762e.

Rahman, SS; Simovic, I; Gibbons, S; Zloh, M; (2011) In silico screening for antibiotic escort molecules to overcome efflux. JOURNAL OF MOLECULAR MODELING , 17 (11) pp. 2863-2872. 10.1007/s00894-011-0978-7.


Said, MM; Gibbons, S; Moffat, AC; Zloh, M; (2011) Near-infrared spectroscopy (NIRS) and chemometric analysis of Malaysian and UK paracetamol tablets: A spectral database study. INTERNATIONAL JOURNAL OF PHARMACEUTICS , 415 (1-2) pp. 102-109. 10.1016/j.ijpharm.2011.05.057.

Sil, BC; Cook, KM; Schofield, C; Figg, WD; Hilton, ST; (2011) Novel multi-component approaches towards dimeric epidithiodiketopiperazines as anti-cancer agents. In: (Proceedings) 241st National Meeting and Exposition of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Sil, BC; Hilton, ST; (2011) Diversity from simplicity: A common precursor approach towards natural products. In: (Proceedings) 241st National Meeting and Exposition of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Siriwatanametanon, N; Heinrich, M; (2011) The Thai Medicinal Plant Gynura pseudochina var. hispida: Chemical Composition and in vitro NF-KB Inhibitory Activity. NATURAL PRODUCT COMMUNICATIONS , 6 (5) pp. 627-630.

Swain, A; Turton, J; Scudamore, CL; Pereira, I; Viswanathan, N; Smyth, R; Munday, M; ... York, M; + view all (2011) Urinary biomarkers in hexachloro-1:3-butadiene-induced acute kidney injury in the female Hanover Wistar rat; correlation of alpha-glutathione S-transferase, albumin and kidney injury molecule-1 with histopathology and gene expression. JOURNAL OF APPLIED TOXICOLOGY , 31 (4) pp. 366-377. 10.1002/jat.1624.




Viladoms, J; Scott, LG; Fedor, MJ; (2011) An Active-Site Guanine Participates in glmS Ribozyme Catalysis in Its Protonated State. Journal of the American Chemical Society , 133 (45) 18388-18396-18388-18396. 10.1021/ja207426j.


Wilderspin, AF; Nkansah, E; Zinzalla, G; Stephenson, FA; Thurston, DE; (2011) Use of GFP-STAT3 beta tc for EMSA analysis of protein-protein and protein-DNA interactions in tumorigenic signalling pathways. CANCER RESEARCH , 71 10.1158/1538-7445.AM2011-279.

This list was generated on Sun Jun 16 03:12:19 2019 BST.