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Number of items: 67.

Article

Appleton, K; Mackay, HJ; Judson, I; Plumb, JA; McCormick, C; Strathdee, G; Lee, C; ... Brown, R; + view all (2007) Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. JOURNAL OF CLINICAL ONCOLOGY , 25 (29) pp. 4603-4609. 10.1200/JCO.2007.10.8688.

Bell, HS; Dufes, C; O'Prey, J; Crighton, D; Bergamaschi, D; Lu, X; Schatzlein, AG; ... Ryan, KM; + view all (2007) A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. JOURNAL OF CLINICAL INVESTIGATION , 117 (4) pp. 1008-1018. 10.1172/JCI28920.

Bolam, DN; Roberts, S; Proctor, MR; Turkenburg, JP; Dodson, EJ; Martinez-Fleites, C; Yang, M; ... Gilbert, HJ; + view all (2007) The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 104 (13) pp. 5336-5341. 10.1073/pnas.0607897104.

Campbell, NH; Parkinson, GN; (2007) Crystallographic studies of quadruplex nucleic acids. METHODS , 43 (4) pp. 252-263. 10.1016/j.ymeth.2007.08.005.

Dawson, S; Malkinson, JP; Paumier, D; Searcey, M; (2007) Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies. NATURAL PRODUCT REPORTS , 24 (1) pp. 109-126. 10.1039/b516347c.

Garcia-Saez, I; DeBonis, S; Lopez, R; Trucco, F; Rousseau, B; Thuery, P; Kozielski, F; (2007) Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration. JOURNAL OF BIOLOGICAL CHEMISTRY , 282 (13) pp. 9740-9747. 10.1074/jbc.M608883200..

Garcia-Saez, I; DeBonis, S; Lopez, R; Trucco, F; Rousseau, B; Thuéry, P; Kozielski, F; (2007) Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration. J Biol Chem , 282 (13) pp. 9740-9747. 10.1074/jbc.M608883200.

Groc, L; Choquet, D; Stephenson, FA; Verrier, D; Manzoni, OJ; Chavis, P; (2007) NMDA receptor surface trafficking and synaptic subunit composition are developmentally regulated by the extracellular matrix protein reelin. JOURNAL OF NEUROSCIENCE , 27 (38) pp. 10165-10175. 10.1523/JNEUROSCI.1772-07.2007.

Guo, X; Evans, TRJ; Somanath, S; Armesilla, AL; Darling, JL; Schatzlein, A; Cassidy, J; (2007) In vitro evaluation of cancer-specific NF-kappa B-CEA enhancer-promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines. BRITISH JOURNAL OF CANCER , 97 (6) pp. 745-754. 10.1038/sj.bjc.6603930.

Hadjivassileva, T; Stapleton, PD; Thurston, DE; Taylor, PW; (2007) Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus. Int J Antimicrob Agents , 29 (6) pp. 672-678. 10.1016/j.ijantimicag.2007.01.005.

Haider, S; Khalid, S; Tucker, SJ; Ashcroft, FM; Sansom, MSP; (2007) Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: A comparative study. BIOCHEMISTRY , 46 (12) pp. 3643-3652. 10.1021/bi062210f.

Haider, S; Tarasov, AI; Craig, TJ; Sansom, MSP; Ashcroft, FM; (2007) Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis. EMBO JOURNAL , 26 (16) pp. 3749-3759. 10.1038/sj.emboj.7601809.

Harrison, CA; Bastan, R; Peirce, MJ; Munday, MR; Peachell, PT; (2007) Role of calcineurin in the regulation of human lung mast cell and basophil function by cyclosporine and FK506. BRITISH JOURNAL OF PHARMACOLOGY , 150 (4) pp. 509-518. 10.1038/sj.bjp.0707002.

Heinrich, M; Modarai, M; Kortenkamp, A; (2007) Drug interactions with Echinacea: does it matter how the product is made? JOURNAL OF PHARMACY AND PHARMACOLOGY , 59 A80-A80.

Hilton, ST; Jones, K; (2007) The tandem radical route to indole alkaloids: an unusual rearrangement reaction. ARKIVOC pp. 120-128.

Klein, E; DeBonis, S; Thiede, B; Skoufias, DA; Kozielski, F; Lebeau, L; (2007) New chemical tools for investigating human mitotic kinesin Eg5. BIOORGANIC & MEDICINAL CHEMISTRY , 15 (19) pp. 6474-6488. 10.1016/j.bmc.2007.06.016.

Kokubun, T; Shiu, WKP; Gibbons, S; (2007) Inhibitory activities of lichen-derived compounds against methicillin- and multidrug-resistant Staphylococcus aureus. PLANTA MEDICA , 73 (2) pp. 176-179. 10.1055/s-2006-957070.

Kozielski, F; DeBonis, S; Skoufias, DA; (2007) Screening for inhibitors of microtubule-associated motor proteins. Methods Mol Med , 137 pp. 189-207.

Lee, MPH; Parkinson, GN; Hazel, P; Neidle, S; (2007) Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 129 (33) 10106-+. 10.1021/ja0740869.

Michalet, S; Cartier, G; David, B; Mariotte, A-M; Dijoux-franca, M-G; Kaatz, GW; Stavri, M; (2007) N-Caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 17 (6) pp. 1755-1758. 10.1016/j.bmcl.2006.12.059.

Modarai, M; Gertsch, J; Suter, A; Heinrich, M; Kortenkamp, A; (2007) Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content. JOURNAL OF PHARMACY AND PHARMACOLOGY , 59 (4) pp. 567-573. 10.1211/jpp.59.4.0012.

Modarai, M; Wilson, N; Politi, M; Suter, A; Kortenkamp, A; Heinrich, M; (2007) Echinacea liquid formulations - NMR spectroscopy and multivariate data analysis of fractions with CYP3A4 inhibitory activity. JOURNAL OF PHARMACY AND PHARMACOLOGY , 59 A63-A63.

Nichols, CE; Johnson, C; Lamb, HK; Lockyer, M; Charles, IG; Hawkins, AR; Stammers, DK; (2007) Structure of the ribosomal interacting GTPase YjeQ from the enterobacterial species Salmonella typhimurium. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS , 63 pp. 922-928. 10.1107/S1744309107048609.

Nichols, CE; Lamb, HK; Lockyer, M; Charles, IG; Pyne, S; Hawkins, AR; Stammers, DK; (2007) Characterization of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS , 68 (1) pp. 13-25. 10.1002/prot.21386.

O'Donnell, G; Gibbons, S; (2007) Antibacterial activity of two canthin-6-one alkaloids from Allium neapolitanum. PHYTOTHERAPY RESEARCH , 21 (7) pp. 653-657. 10.1002/ptr.2136.

Palmer, AM; Stephenson, FA; Williams, RJ; Society for Medicines Research Committee, ; (2007) Society for Medicines Research: 40th anniversary symposium. Drug News Perspect , 20 (3) pp. 191-196.

Parkinson, GN; Ghosh, R; Neidle, S; (2007) Structural basis for binding of porphyrin to human telomeres. BIOCHEMISTRY , 46 (9) pp. 2390-2397. 10.1021/bi062244n.

Prieto, JM; Iacopini, P; Cioni, P; Chericoni, S; (2007) In vitro activity of the essential oils of Origanum vulgare, Satureja montana and their main constituents in peroxynitrite-induced oxidative processes. FOOD CHEMISTRY , 104 (3) pp. 889-895. 10.1016/j.foodchem.2006.01.064.

Prieto, JM; Schaffner, U; Barker, A; Braca, A; Siciliano, T; Boevé, J-L; (2007) Sequestration of furostanol saponins by Monophadnus sawfly larvae. J Chem Ecol , 33 (3) pp. 513-524. 10.1007/s10886-006-9232-7.

Rahman, MM; Gibbons, S; Gray, AI; (2007) Isoflavanones from Uraria picta and their antimicrobial activity. PHYTOCHEMISTRY , 68 (12) pp. 1692-1697. 10.1016/j.phytochem.2007.04.015.

Rivera, D; Obon, C; Inocencio, C; Heinrich, M; Verde, A; Fajardo, J; Palazon, JA; (2007) Gathered food plants in the mountains of Castilla-La mancha (Spain): Ethnobotany and Multivariate analysis. ECONOMIC BOTANY , 61 (3) pp. 269-289. 10.1663/0013-0001(2007)61[269:GFPITM]2.0.CO;2.

Robins, RJ; Gibbons, S; Marston, A; (2007) The fiftieth anniversary meeting of the Phytochemical Society of Europe: Churchill College, Cambridge, 11-14 April 2007 Highlights in the Evolution of Phytochemistry. PHYTOCHEMISTRY , 68 (22-24) pp. 2699-2704. 10.1016/j.phytochem.2007.10.003.

Schrettl, M; Bignell, E; Kragl, C; Sabiha, Y; Loss, O; Eisendle, M; Wallner, A; ... Haas, H; + view all (2007) Distinct Roles for Intra- and Extracellular Siderophores during Aspergillus fumigatus Infection. PLoS Pathogens , 3 (9) , Article e128. 10.1371/journal.ppat.0030128. Green open access
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Smith, ECJ; Kaatz, GW; Seo, SM; Wareham, N; Williamson, EA; Gibbons, S; (2007) The phenolic diterpene totarol inhibits multidrug efflux pump activity in Staphylococcus aureus. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY , 51 (12) pp. 4480-4483. 10.1128/AAC.00216-07.

Smith, ECJ; Williamson, EM; Wareham, N; Kaatz, GW; Gibbons, S; (2007) Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana. PHYTOCHEMISTRY , 68 (2) pp. 210-217. 10.1016/j.phytochem.2006.10.001.

Smith, MJ; Pozo, K; Stephenson, FA; (2007) Yeast two-hybrid studies. pp. 409-421. 10.1007/978-0-387-30401-4_19.

Smyth, R; Munday, MR; York, MJ; Clarke, CJ; Dare, T; Turton, JA; (2007) Comprehensive characterization of serum clinical chemistry parameters and the identification of urinary superoxide dismutase in a carbon tetrachloride-induced model of hepatic fibrosis in the female Hanover Wistar rat. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY , 88 (5) pp. 361-376. 10.1111/j.1365-2613.2007.00543.x.

Stapleton, PD; Shah, S; Ehlert, K; Hara, Y; Taylor, PW; (2007) The beta-lactam-resistance modifier (-)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus. Microbiology , 153 (Pt 7) pp. 2093-2103. 10.1099/mic.0.2007/007807-0.

Stapleton, PD; Shah, S; Ehlert, K; Hara, Y; Taylor, PW; (2007) The β-lactam-resistance modifier (-)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureas. Microbiology , 153 (7) pp. 2093-2103. 10.1099/mic.0.2007/007807-0.

Stavri, M; Piddock, LJV; Gibbons, S; (2007) Bacterial efflux pump inhibitors from natural sources. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY , 59 (6) pp. 1247-1260. 10.1093/jac/dkl460.

Todd, AK; Haider, SM; Parkinson, GN; Neidle, S; (2007) Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter. Nucleic Acids Res , 35 (17) 5799 - 5808. 10.1093/nar/gkm609. Green open access
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Uddin, SJ; Nahar, L; Shilpi, JA; Shoeb, M; Borkowski, T; Gibbons, S; Middleton, M; ... Sarker, SD; + view all (2007) Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo-2 colon cancer cell line in vitro. PHYTOTHERAPY RESEARCH , 21 (8) pp. 757-761. 10.1002/ptr.2159.

White, EW; Tanious, F; Ismail, MA; Reszka, AP; Neidle, S; Boykin, DW; Wilson, WD; (2007) Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge. BIOPHYSICAL CHEMISTRY , 126 (1-3) pp. 140-153. 10.1016/j.bpc.2006.06.006.

Woon, ECY; Arcieri, M; Wilderspin, AF; Malkinson, JP; Searcey, M; (2007) Solid-phase synthesis of chlorofusin analogues. JOURNAL OF ORGANIC CHEMISTRY , 72 (14) pp. 5146-5151. 10.1021/jo070450a.

Xiao, ZY; Mu, Q; Shiu, WKP; Zeng, YH; Gibbons, S; (2007) Polyisoprenylated benzoylphloroglucinol derivatives from Hypericum sampsonii. JOURNAL OF NATURAL PRODUCTS , 70 (11) pp. 1779-1782. 10.1021/np0704147.

Yang, M; Davies, GJ; Davis, BG; (2007) A glycosynthase catalyst for the synthesis of flavonoid glycosides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , 46 (21) pp. 3885-3888. 10.1002/anie.200604177.

Zloh, M; Bucar, F; Gibbons, S; (2007) Quantum chemical studies on structure activity relationship of natural product polyacetylenes. THEORETICAL CHEMISTRY ACCOUNTS , 117 (2) pp. 247-252. 10.1007/s00214-006-0148-7.

Zloh, M; Gibbons, S; (2007) The role of small molecule-small molecule interactions in overcoming biological barriers for antibacterial drug action. THEORETICAL CHEMISTRY ACCOUNTS , 117 (2) pp. 231-238. 10.1007/s00214-006-0149-6.

Proceedings paper

Dufes, C; Bell, HS; Chisholm, EJ; Ryan, K; Mather, S; Uchegbu, IF; Vassaux, G; (2007) Tumor-specific delivery of p73-directed genetic therapies. In: (Proceedings) 15th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy. (pp. p. 956). MARY ANN LIEBERT INC

Franklin, BD; Seedat, H; Heinrich, M; (2007) Use of herbal remedies by patients admitted to hospital. In: (pp. A243-A244). SPRINGER

Gibbons, S; (2007) Phytochemicals for bacterial resistance - strengths, weaknesses and opportunities. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 798). GEORG THIEME VERLAG KG

Guo, X; Evans, TRJ; Armesilla, AL; Darling, JL; Schatzlein, A; Cassidy, J; Wang, W; (2007) In vitro evaluation of cancer-specific NF-kappa B-CEA enhancer-promoter system for gene-directed enzyme prodrug therapy in colon cancer cell lines. In: (Proceedings) 15th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy. (pp. p. 1006). MARY ANN LIEBERT INC

Heinrich, M; (2007) Herbal medicines in health care - Benefits and risks. In: (Proceedings) Annual Congress of the British-Toxicological-Society. (pp. pp. 148-149). ELSEVIER IRELAND LTD

Heinrich, M; Modarai, M; Kortenkamp, A; (2007) CYP inhibitory action of Echinacea preparations differs widely, but is it clinically relevant? In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 823). GEORG THIEME VERLAG KG

Ka Po Shiu, W; Gibbons, S; (2007) Isolation and characterization of a new dibenzofuran from Hypericum revolutum ssp revolutum Vahl. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 943). GEORG THIEME VERLAG KG

Lechner, D; Gibbons, S; Bucar, F; (2007) Modulation of isoniazid susceptibility of mycobacterial strains by different flavonoids. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 848). GEORG THIEME VERLAG KG

MacLellan, S; Uchegbu, IF; Holmes, W; Condon, B; Schatzlein, AG; (2007) Dynamic contrast enhanced, magnetic resonance imaging (DCE-MRI) as a predictor of drug and nanomedicine transport in solid tumour models. In: (pp. A2-A2). PHARMACEUTICAL PRESS-ROYAL PHARMACEUTICAL SOC GREAT BRITIAN

Modarai, M; Wilson, N; Politi, M; Suter, A; Kortenkamp, A; Heinrich, M; (2007) Evaluating CYP3A4 inhibitory activity of Echinacea extracts using NMR and multivariate data analysis. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. pp. 990-991). GEORG THIEME VERLAG KG

Peschel, W; Politi, M; Wilson, N; Constanti, A; Prieto, GJM; Heinrich, M; (2007) Cannabis tinctures and extracts - in vitro profiling for cytotoxic and anti-inflammatory effects. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. pp. 841-842). GEORG THIEME VERLAG KG

Politi, M; Prieto, JM; Heinrich, M; (2007) Direct metabolic fingerprinting by NMR spectroscopy as a new method for the analysis of herbal tinctures. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 903). GEORG THIEME VERLAG KG

Rahman, MM; Gibbons, S; (2007) The anti-staphylococcal activity of terpenes from Commiphora molmol Engl. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 872). GEORG THIEME VERLAG KG

Shiu, KP; Gibbons, S; (2007) The anti-staphylococcal activity of Hypericum species. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. pp. 872-873). GEORG THIEME VERLAG KG

Smith, E; Gibbons, S; (2007) 2 beta-acetoxyferruginol - a new antibacterial abietane diterpene from Prumnopitys andina. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 807). GEORG THIEME VERLAG KG

Smith, E; Gibbons, S; (2007) Myrceocommunic acid - a labdane diterpene with activity against Staphylococcus aureus and Propionibacterium acnes. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 944). GEORG THIEME VERLAG KG

Stavri, M; Gibbons, S; (2007) Antibacterial constituents from Plectranthus ciliatus. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 873). GEORG THIEME VERLAG KG

Stavri, M; Gibbons, S; (2007) New diterpenes from Plectranthus emstii. In: (Proceedings) 55th Annual Congress of the Society-for-Medicinal-Plant-Research. (pp. p. 873). GEORG THIEME VERLAG KG

Thesis

George, Jonathan Harry; (2007) Synthetic studies on the azinothricin family of antitumour antibiotics. Doctoral thesis , UCL (University College London). Green open access
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This list was generated on Sun Aug 18 02:53:59 2019 BST.