UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Author | Type
Jump to: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | R | S | T | U | V | W | Y | Z
Number of items: 185.

A

Abbosh, C; Birkbak, NJ; Wilson, GA; Jamal-Hanjani, M; Constantin, T; Salari, R; Le Quesne, J; ... Dessimoz, C; + view all (2017) Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution. Nature , 545 pp. 446-451. 10.1038/nature22364. Green open access
file

Abbosh, C; Venkatesan, S; Janes, SM; Fitzgerald, RC; Swanton, C; (2017) Evolutionary dynamics in pre-invasive neoplasia. Current Opinion in System Biology , 2 pp. 1-8. 10.1016/j.coisb.2017.02.009. Green open access
filefile

Abrol, E; Groszmann, M; Pitman, A; Hough, R; Taylor, RM; Aref-Adib, G; (2017) Exploring the digital technology preferences of teenagers and young adults (TYA) with cancer and survivors: a cross-sectional service evaluation questionnaire. Journal of Cancer Survivorship , 11 (6) pp. 670-682. 10.1007/s11764-017-0618-z. Green open access
file

Alrifai, D; (2017) Evaluation of CA 19-9, a predictive biomarker of response and survival in patients undergoing chemotherapy for metastatic pancreatic ductal adenocarcinoma. Presented at: ESMO World Congress on Gastrointestinal Cancer 2018, Barcelona, Spain. Green open access
file

Angelis, A; Montibeller, G; Hochhauser, D; Kanavos, P; (2017) Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting. BMC Medical Informatics and Decision Making , 17 (1) , Article 149. 10.1186/s12911-017-0524-3. Green open access
file

B

Barbieri, CE; Chinnaiyan, AM; Lerner, SP; Swanton, C; Rubin, MA; (2017) The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics. European Urology , 71 (2) pp. 237-246. 10.1016/j.eururo.2016.08.024. Green open access
file

Barrett, JE; Feber, A; Herrero, J; Tanic, M; Wilson, GA; Swanton, C; Beck, S; (2017) Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection. BMC Bioinformatics , 18 , Article 354. 10.1186/s12859-017-1753-2. Green open access
filefile

Baurain, J; Awada, A; Brunsvig, P; Kristeleit, RS; Loirat, D; Jossang, D; Zitvogel, L; ... Spicer, J; + view all (2017) A phase I dose escalation study of intra-tumoral LTX-315 as monotherapy or in combination with either ipilimumab or pembrolizumab in patients with transdermally accessible tumors (NCT01986426). Presented at: AACR Annual Meeting 2017, Washington, D.C., USA. Green open access
file

Bentham, RB; Bryson, K; Szabadkai, G; (2017) MCbiclust: a novel algorithm to discover large-scale functionally related gene sets from massive transcriptomics data collections. Nucleic Acids Research , 45 (15) pp. 8712-8730. 10.1093/nar/gkx590. Green open access
file

Berenjeno, IM; Piñeiro, R; Castillo, SD; Pearce, W; McGranahan, N; Dewhurst, SM; Meniel, V; ... Vanhaesebroeck, B; + view all (2017) Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nature Communications , 8 , Article 1773. 10.1038/s41467-017-02002-4. Green open access
filefilefilefilefilefilefilefile

Bilancio, A; Rinaldi, B; Oliviero, MA; Donniacuo, M; Monti, MG; Boscaino, A; Marino, I; ... Migliaccio, A; + view all (2017) Inhibition of p110δ PI3K prevents inflammatory response and restenosis after artery injury. Bioscience Reports , 37 (5) , Article BSR20171112. 10.1042/BSR20171112. Green open access
file

Bilanges, B; Alliouachene, S; Pearce, W; Morelli, D; Szabadkai, G; Chung, Y-L; Chicanne, G; ... Vanhaesebroeck, B; + view all (2017) Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism. Nature Communications , 8 , Article 1804. 10.1038/s41467-017-01969-4. Green open access
file

Blakely, CM; Watkins, TBK; Wu, W; Gini, B; Chabon, JJ; McCoach, CE; McGranahan, N; ... Bivona, TG; + view all (2017) Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Nature Genetics , 49 (12) pp. 1693-1704. 10.1038/ng.3990. Green open access
file

Bosch-Vilaro, A; Jacobs, B; Pomella, V; Asbagh, LA; Kirkland, R; Michel, J; Singh, S; ... Tejpar, S; + view all (2017) Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells. Oncotarget , 8 (3) pp. 4277-4288. 10.18632/oncotarget.13834. Green open access
file

Brown, N; Carter, T; Mulholland, P; (2017) Adjuvant Chemotherapy is Indicated in Patients with Lower Grade Glioma. Clinical Oncology , 29 (3) pp. 141-142. 10.1016/j.clon.2016.11.006. Green open access
file

Brown, NF; Carter, T; Kitchen, N; Mulholland, P; (2017) Dabrafenib and trametinib in BRAFV600E mutated glioma. CNS Oncology , 6 (4) 10.2217/cns-2017-0006. Green open access
file

Brown, NF; Carter, T; Mulholland, P; (2017) Dabrafenib in BRAFV600-mutated anaplastic pleomorphic xanthoastrocytoma. CNS Oncology , 6 (1) 10.2217/cns-2016-0031. Green open access
file

Butler, CR; Hynds, RE; Crowley, C; Gowers, KH; Partington, L; Hamilton, NJ; Carvalho, C; ... Janes, SM; + view all (2017) Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds. Biomaterials , 124 pp. 95-105. 10.1016/j.biomaterials.2017.02.001. Green open access
file

Butt, MA; Pye, H; Haidry, RJ; Oukrif, D; Khan, SU; Puccio, I; Gandy, M; ... Lovat, LB; + view all (2017) Upregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugate. Oncotarget , 8 pp. 25080-25096. 10.18632/oncotarget.15340. Green open access
file

Böiers, C; Richardson, SE; Laycock, E; Zriwil, A; Turati, VA; Brown, J; Wray, JP; ... Enver, T; + view all (2017) A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1. Developmental Cell 10.1016/j.devcel.2017.12.005. (In press). Green open access
file

C

Calvo, E; Moreno, V; Flynn, M; Holgado, E; Olmedo, ME; Criado, MPL; Kahatt, C; ... Forster, M; + view all (2017) Antitumor activity of lurbinectedin (PM01183) and doxorubicin in relapsed small-cell lung cancer: results from a phase I study. Annals of Oncology , 28 (10) pp. 2559-2566. 10.1093/annonc/mdx357. Green open access
file

Caswell, DR; Swanton, C; (2017) The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome. [Review]. BMC Medicine , 15 , Article 133. 10.1186/s12916-017-0900-y. Green open access
file

Choueiri, TK; Plimack, E; Arkenau, H-T; Jonasch, E; Heng, DYC; Powles, T; Frigault, MM; ... Pal, SK; + view all (2017) Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer. Journal of Clinical Oncology , 35 (26) pp. 2993-3001. 10.1200/JCO.2017.72.2967. Green open access
file

Colbeck, EJ; Ager, A; Gallimore, A; Jones, GW; (2017) Tertiary Lymphoid Structures in Cancer: Drivers of Antitumor immunity, immunosuppression, or Bystander Sentinels in Disease? Frontiers in Immunology , 8 (ARTN 183) , Article 1830. 10.3389/fimmu.2017.01830. Green open access
file

Colbeck, EJ; Jones, E; Hindley, JP; Smart, K; Schulz, R; Browne, M; Cutting, S; ... Gallimore, A; + view all (2017) Treg Depletion Licenses T Cell-Driven HEV Neogenesis and Promotes Tumor Destruction. Cancer Immunology Research , 5 (11) 10.1158/2326-6066.CIR-17-0131. Green open access
file

Conteduca, V; Wetterskog, D; Sharabiani, MTA; Grande, E; Fernandez-Perez, MP; Jayaram, A; Salvi, S; ... Spanish Oncology Genitourinary Group, .; + view all (2017) Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study. Annals of Oncology , 28 (7) pp. 1508-1516. 10.1093/annonc/mdx155. Green open access
filefile

Corrie, P; Qian, W; Basu, B; Valle, JW; Falk, S; Iwuji, C; Wasan, HS; ... Jodrell, DI; + view all (2017) A randomized phase II trial comparing different schedules of nab-paclitaxel (nabP) combined with gemcitabine (GEM) as first line treatment for metastatic pancreatic adenocarcinoma (mPDAC). Presented at: 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Cox, S; Hurt, C; Grenader, T; Mukherjee, S; Bridgewater, J; Crosby, T; (2017) The prognostic value of derived neutrophil to lymphocyte ratio in oesophageal cancer treated with definitive chemoradiotherapy. Radiotherapy and Oncology , 125 (1) pp. 154-159. 10.1016/j.radonc.2017.08.023. Green open access
filefilefilefile

Crockford, A; Zalmas, LP; Grönroos, E; Dewhurst, SM; McGranahan, N; Cuomo, ME; Encheva, V; ... Swanton, C; + view all (2017) Cyclin D mediates tolerance of genome-doubling in cancers with functional p53. Annals of Oncology , 28 (1) pp. 149-156. 10.1093/annonc/mdw612. Green open access
file

Crosby, T; Hurt, CN; Falk, S; Gollins, S; Staffurth, J; Ray, R; Bridgewater, JA; ... Mukherjee, S; + view all (2017) Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/- cetuximab in oesophageal cancer. British Journal of Cancer , 116 pp. 709-716. 10.1038/bjc.2017.21. Green open access
file

D

Davda, R; Prentice, M; Sarova, A; Nei, W; Orczyk, C; Arya, M; Moore, C; ... Payne, H; + view all (2017) Late Toxicity and Patient Reported Outcomes in Patients Treated With Salvage Radiation Following Primary High Intensity Focal Ultrasound for Localized Prostate Cancer. Presented at: 59th Annual Meeting of the American-Society-for-Therapeutic-Radiation-Oncology (ASTRO), San Diego, CA.

Davidson, SM; Riquelme, JA; Takov, K; Vicencio, JM; Boi-Doku, C; Khoo, V; Doreth, C; ... Yellon, DM; + view all (2017) Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro. Journal of Cellular and Molecular Medicine 10.1111/jcmm.13302. (In press). Green open access
file

Diamond, JR; Goff, B; Forster, MD; Bendell, JC; Britten, CD; Gordon, MS; Gabra, H; ... Moore, KM; + view all (2017) Phase Ib study of the mitochondrial inhibitor ME-344 plus topotecan in patients with previously treated, locally advanced or metastatic small cell lung, ovarian and cervical cancers. Investigational New Drugs , 35 (5) pp. 627-633. 10.1007/s10637-017-0444-1. Green open access
filefile

Dikaios, N; Atkinson, D; Tudisca, C; Purpura, P; Forster, M; Ahmed, H; Beale, T; ... Punwani, S; + view all (2017) A comparison of Bayesian and non-linear regression methods for robust estimation of pharmacokinetics in DCE-MRI and how it affects cancer diagnosis. Computerized Medical Imaging and Graphics , 56 pp. 1-10. 10.1016/j.compmedimag.2017.01.003. Green open access
file

Dillon, MT; Espinasse, A; Ellis, S; Mohammed, K; Grove, LG; McLellan, L; Smith, SA; ... Harrington, KJ; + view all (2017) A Phase I dose-escalation study of ATR inhibitor monotherapy with AZD6738 in advanced solid tumors (PATRIOT Part A). Presented at: Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC. Green open access
file

Diocou, S; Volpe, A; Jauregui-Osoro, M; Boudjemeline, M; Chuamsaamarkkee, K; Man, F; Blower, PJ; ... Fruhwirth, GO; + view all (2017) [(18)F]tetrafluoroborate-PET/CT enables sensitive tumor and metastasis in vivo imaging in a sodium iodide symporter-expressing tumor model. Scientific Reports , 7 , Article 946. 10.1038/s41598-017-01044-4. Green open access
file

Domingues, PH; Nanduri, LSY; Seget, K; Venkateswaran, SV; Agorku, D; Vigano, C; von Schubert, C; ... Hardt, O; + view all (2017) Cellular Prion Protein PrPC and Ecto-5′-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy. Cancer Research , 77 (11) pp. 2914-2926. 10.1158/0008-5472.CAN-16-3052. Green open access
file

Dyson, AP; Dal-Pizzol, F; Sabbatini, G; Lach, AB; Galfo, F; Dos Santos Cardoso, J; Pescador Mendonça, B; ... Singer, M; + view all (2017) INORGANIC THIOMETALLATES AS A NEW CLASS OF SULFIDE-DONORS: CHEMISTRY, PHARMACOLOGY AND IMPACT ON ISCHEMIA/REPERFUSION INJURY. [Dataset]. Bloomsbury Institute of Intensive Care Medicine, Division of Medicine: London, UK. Green open access
file

E

Edeline, J; Blanc, J-F; Campillo-Gimenez, B; Ma, Y-T; King, J; Faluyi, O; Mathurin, J; ... Meyer, T; + view all (2017) Prognostic scores for sorafenib-treated hepatocellular carcinoma patients: A new application for the hepatoma arterial embolisation prognostic score. European Journal of Cancer , 86 pp. 135-142. 10.1016/j.ejca.2017.08.036. Green open access
filefile

Eisenblaetter, M; Flores-Borja, F; Lee, JJ; Wefers, C; Smith, H; Hueting, R; Cooper, MS; ... Ng, T; + view all (2017) Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment. Theranostics , 7 (9) pp. 2392-2401. 10.7150/thno.17138. Green open access
file

El-Khoueiry, AB; Sangro, B; Yau, T; Crocenzi, TS; Kudo, M; Hsu, C; Kim, T-Y; ... Melero, I; + view all (2017) Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial. Lancet , 389 (10088) pp. 2492-2502. 10.1016/S0140-6736(17)31046-2. Green open access
file

Elliott, MJ; Butler, CR; Varanou-Jenkins, A; Partington, L; Carvalho, C; Samuel, E; Crowley, C; ... Birchall, MA; + view all (2017) Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine. Stem Cells Translational Medicine , 6 (6) pp. 1458-1464. 10.1002/sctm.16-0443. Green open access
file

Espana-Agusti, J; Warren, A; Chew, SK; Adams, DJ; Matakidou, A; (2017) Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis. Nature Communications , 8 , Article 2026. 10.1038/s41467-017-02245. Green open access
file

Ezquer, FE; Ezquer, ME; Vicencio, JM; Calligaris, SD; (2017) Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue receptivity. Cell Adhesion & Migration , 11 (1) pp. 110-119. 10.1080/19336918.2016.1197480. Green open access
file

F

Feber, A; Dhami, P; Dong, L; de Winter, P; Tan, WS; Martínez-Fernández, M; Paul, DS; ... Kelly, JD; + view all (2017) UroMark - a urinary biomarker assay for the detection of bladder cancer. Clinical Epigenetics , 9 , Article 8. 10.1186/s13148-016-0303-5. Green open access
file

Ferolla, P; Brizzi, MP; Meyer, T; Mansoor, W; Mazieres, J; Do Cao, C; Léna, H; ... Baudin, E; + view all (2017) Efficacy and safety of long-acting pasireotide or everolimus alone or in combination in patients with advanced carcinoids of the lung and thymus (LUNA): an open-label, multicentre, randomised, phase 2 trial. The Lancet Oncology , 18 (12) pp. 1652-1664. 10.1016/S1470-2045(17)30681-2. Green open access
file

Flynn, MJ; Hartley, JA; (2017) The emerging role of anti-CD25 directed therapies as both immune modulators and targeted agents in cancer. [Review]. British Journal of Haematology , 179 (1) pp. 20-35. 10.1111/bjh.14770. Green open access
file

Formica, V; Doldo, E; Antonetti, FR; Nardecchia, A; Ferroni, P; Riondino, S; Morelli, C; ... Roselli, M; + view all (2017) Biological and predictive role of ERCC1 polymorphisms in cancer. Critical Reviews in Oncology/Hematology , 111 pp. 133-143. 10.1016/j.critrevonc.2017.01.016. Green open access
file

Forster, MD; Moreno, V; Boni, V; Guerra, E; Poveda, A; Kristeleit, R; Kahatt, CM; ... Calvo, E; + view all (2017) Activity of lurbinectedin (PM01183) as single agent and in combination in patients with endometrial cancer. Presented at: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL. Gold open access

Forster, MD; Moschetta, M; Uccello, M; Kasenda, B; Mak, G; McClelland, A; Boussios, S; (2017) Dynamics of neutrophils to lymphocyte ratio (NLR) predict outcomes of PD-1/PD-L1 blockade. BioMed Research International , 2017 , Article 1506824. 10.1155/2017/1506824. Green open access
file

Foy, V; Schenk, MW; Baker, K; Gomes, F; Lallo, A; Frese, KK; Forster, M; ... Blackhall, F; + view all (2017) Targeting DNA damage in SCLC. [Review]. Lung Cancer , 114 pp. 12-22. 10.1016/j.lungcan.2017.10.006. Green open access
file

G

George, A; Kristeleit, R; Rafii, S; Michie, CO; Bowen, R; Michalarea, V; van Hagen, T; ... Yap, TA; + view all (2017) Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials. European Journal of Cancer , 76 pp. 52-59. 10.1016/j.ejca.2017.01.020. Green open access
file

Gillessen, S; Attard, G; Beer, TM; Beltran, H; Bossi, A; Bristow, R; Carver, B; ... Omlin, A; + view all (2017) Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017. European Urology 10.1016/j.eururo.2017.06.002. (In press). Green open access
file

Gowers, KHC; Hynds, RE; Thakrar, RM; Carroll, B; Birchall, MA; Janes, SM; (2017) Optimized isolation and expansion of human airway epithelial basal cells from endobronchial biopsy samples. Journal of Tissue Engineering and Regenerative Medicine 10.1002/term.2466. (In press). Green open access
filefile

Greystoke, A; Steele, N; Arkenau, H-T; Blackhall, F; Haris, NM; Lindsay, CR; Califano, R; ... Dean, E; + view all (2017) SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting. British Journal of Cancer , 117 pp. 938-946. 10.1038/bjc.2017.271. Green open access
filefilefilefilefile

H

Hamilton, NJI; Lee, DDH; Gowers, KHC; Butler, CR; Hynds, RE; Birchall, MA; Janes, SM; (2017) Use of a decellularised dermis scaffold and human bronchial epithelial cells to tissue engineer airway mucosa suitable for tracheal transplantation. Presented at: Spring Meeting on Clinician Scientists in Training, London, ENGLAND.

Harpreet, W; Guy, VH; Volker, H; Navesh, S; Julien, T; Jens, R; Marc, P; ... Peter, G; + view all (2017) Overall survival analysis of the FOXFIRE-SIRFLOX-FOXFIRE global prospective randomized studies of first-line selective internal radiotherapy (SIRT) in patients with liver metastases from colorectal cancer. Presented at: ESMO 19th World Congress on Gastrointestinal Cancer, Barcelona, SPAIN.

Harrington, K; Hall, E; Hawkins, M; Henry, A; MacKay, R; Maughan, T; McDonald, A; ... Faivre-Finn, C; + view all (2017) Introducing the Cancer Research UK Advanced Radiotherapy Technologies Network (ART-NET). Clinical Oncology , 29 (11) pp. 707-710. 10.1016/j.clon.2017.07.016. Green open access
file

Heather, JM; Ismail, M; Oakes, T; Chain, B; (2017) High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities. Brief Bioinform 10.1093/bib/bbw138. (In press). Green open access
file

Helfen, A; Roth, J; Ng, T; Eisenblaetter, M; (2017) In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment. Journal of Nuclear Medicine , 59 (2) pp. 183-188. 10.2967/jnumed.117.198952. Green open access
file

Hsieh, JJ; Purdue, MP; Signoretti, S; Swanton, C; Albiges, L; Schmidinger, M; Heng, DY; ... Ficarra, V; + view all (2017) Renal cell carcinoma. Nature Reviews Disease Primers , 3 , Article 17009. 10.1038/nrdp.2017.9. Green open access
file

Hynds, RE; Bonfanti, P; Janes, SM; (2017) Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond. EMBO Molecular Medicine , 2017 , Article e8213. 10.15252/emmm.201708213. Green open access
file

Hynds, RE; Janes, SM; (2017) Airway Basal Cell Heterogeneity and Lung Squamous Cell Carcinoma. Cancer Prevention Research , 10 (9) pp. 491-493. 10.1158/1940-6207.CAPR-17-0202. Green open access
file

I

Ignacio, M; Anthony, E-K; Thomas, Y; Chiun, H; Masatoshi, K; Todd, C; Tae-You, K; ... Tim, M; + view all (2017) Efficacy and safety of nivolumab in patients with advanced hepatocellular carcinoma analyzed by patient age: A sub-analysis of the CheckMate 040 study. Presented at: ESMO 19th World Congress on Gastrointestinal Cancer, Barcelona, SPAIN.

Irshad, S; Flores-Borja, F; Lawler, K; Monypenny, J; Evans, R; Male, V; Gordon, P; ... Ng, T; + view all (2017) RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers. Cancer Research , 77 (5) pp. 1083-1096. 10.1158/0008-5472.CAN-16-0598. Green open access
file

Islam, MS; Saito, JA; Emdad, EM; Ahmed, B; Islam, MM; Halim, A; Hossen, QMM; ... Alam, M; + view all (2017) Comparative genomics of two jute species and insight into fibre biogenesis. Nature Plants , 3 (2) , Article 16223. 10.1038/nplants.2016.223. Green open access
file

Iyer, RV; Acquisto, SG; Bridgewater, JA; Choti, MA; Hong, TS; Kis, B; Mead, PA; ... Valle, JW; + view all (2017) Guidelines for management of urgent symptoms in cholangiocarcinoma (CC) patients (pts) with biliary stents or catheters using the modified RAND/UCLA Delphi process. Presented at: 53rd Annual Clinical Science Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Symposium on Old Targets, New Drugs - Her2 and MET, Chicago, IL.

J

Jamal-Hanjani, M; Wilson, GA; McGranahan, N; Birkbak, NJ; Watkins, TBK; Veeriah, S; Shafi, S; ... Swanton, C; + view all (2017) Tracking the Evolution of Non-Small-Cell Lung Cancer. New England Journal of Medicine , 376 (22) pp. 2109-2121. 10.1056/NEJMoa1616288. Green open access
file

James, ND; de Bono, JS; Spears, MR; Clarke, NW; Mason, MD; Dearnaley, DP; Ritchie, AWS; ... STAMPEDE Investigators, ; + view all (2017) Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy. The New England Journal of Medicine , 377 pp. 338-351. 10.1056/NEJMoa1702900. Green open access
file

Jones, OS; Vassie, C; Gilson, R; Lechner, M; (2017) Until eradication, awareness. Lancet Infectious Diseases , 17 (4) pp. 368-369. 10.1016/S1473-3099(17)30125-1. Green open access
file

K

Karpathakis, A; Dibra, H; Pipinikas, C; Feber, A; Morris, T; Francis, JM; Oukrif, D; ... Thirlwell, C; + view all (2017) Progressive epigenetic dysregulation in neuroendocrine tumour liver metastasis. Endocrine-Related Cancer , 24 (2) L21-L25. 10.1530/ERC-16-0419. Green open access
file

Kennedy, A; Brown, DB; Feilchenfeldt, J; Marshall, J; Wasan, H; Fakih, M; Gibbs, P; ... Sharma, RA; + view all (2017) Safety of selective internal radiation therapy (SIRT) with yttrium-90 microspheres combined with systemic anticancer agents: expert consensus. Journal of Gastrointestinal Oncology , 8 (6) pp. 1079-1099. 10.21037/jgo.2017.09.10. Green open access
file

Kim, R; Sarker, D; Macarulla, T; Yau, T; Choo, SP; Meyer, T; Hollebecque, A; ... Kang, Y-K; + view all (2017) Phase 1 safety and clinical activity of BLU-554 in advanced hepatocellular carcinoma (HCC). Presented at: 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, SPAIN.

King, J; Palmer, DH; Johnson, P; Ross, P; Hubner, RA; Sumpter, K; Darby, S; ... Meyer, T; + view all (2017) Sorafenib for the Treatment of Advanced Hepatocellular Cancer – a UK Audit. Clinical Oncology , 29 (4) pp. 256-262. 10.1016/j.clon.2016.11.012. Green open access
file

Kinna, AW; (2017) Improved production and purification of recombinant proteins from mammalian expression systems. Doctoral thesis , UCL (University College London). Green open access
file

Kordbacheh, T; Chan, C; Bossons, A; Franks, K; McDonald, F; Forster, M; Mendes, R; ... Faivre-Finn, C; + view all (2017) PARIS: A phase I study of pembrolizumab anti-PD-1 monoclonal antibody in combination with radiotherapy (RT) in locally advanced non-small cell lung cancer (NSCLC). Presented at: UNSPECIFIED.

Kordbacheh, T; Chan, C; Faivre-Finn, C; Franks, K; McDonald, F; Forster, M; Mendes, R; ... Illidge, T; + view all (2017) PD-RAD:A translational study investigating PD-L1 expression after radiotherapy for non-small cell lung cancer (NSCLC). Presented at: UNSPECIFIED.

Kristeleit, R; Davidenko, I; Shirinkin, V; El-Khouly, F; Bondarenko, I; Goodheart, MJ; Gorbunova, V; ... Schilder, RJ; + view all (2017) A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)-only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancer. Gynecologic Oncology , 146 (3) pp. 484-490. 10.1016/j.ygyno.2017.07.005. Green open access
file

Kristeleit, R; Shapiro, GI; Burris, HA; Oza, AM; LoRusso, P; Patel, MR; Domchek, SM; ... Shapira-Frommer, R; + view all (2017) A Phase I-II Study of the Oral PARP Inhibitor Rucaparib in Patients with Germline BRCA1/2-Mutated Ovarian Carcinoma or Other Solid Tumors. Clinical Cancer Research , 23 (15) pp. 4095-4106. 10.1158/1078-0432.CCR-16-2796. Green open access
file

Kristeleit, RS; Lorusso, D; Oaknin, A; Safra, T; Swisher, EM; Bondarenko, IM; Huzarski, T; ... Oza, A; + view all (2017) 988TiP: ARIEL4: An international, randomised phase 3 study of the PARP inhibitor rucaparib vs chemotherapy for the treatment of BRCA-mutated, relapsed, high-grade ovarian cancer. Presented at: 42nd ESMO Congress (ESMO 2017), Madrid, Spain. Green open access
file

Kristeleit, RS; Miller, R; Sellers, L; Brown, N; Devlin, M; Woo, K; Boyd, A; ... Linch, M; + view all (2017) A first-in-human Phase I/II, dose escalation, pharmacokinetic study to assess safety and tolerability of VAL201 in advanced prostate cancer. Presented at: 15th International Congress on Targeted Anticancer Therapies (TAT 2017), Paris, France. Green open access
file

L

Labib, PLZ; Davidson, B; Sharma, RA; Pereira, SP; (2017) Locoregional therapies in cholangiocarcinoma. Hepatic Oncology , 4 (4) pp. 99-109. 10.2217/hep-2017-0014. Green open access
file

Lamarca, A; Walter, T; Pavel, M; Borbath, I; Freis, P; Nuñez, B; Childs, A; ... Barriuso, J; + view all (2017) Design and Validation of the GI-NEC Score to Prognosticate Overall Survival in Patients With High-Grade Gastrointestinal Neuroendocrine Carcinomas. Journal of the National Cancer Institute , 109 (5) 10.1093/jnci/djw277. Green open access
file

Lampada, A; O'Prey, J; Szabadkai, G; Ryan, KM; Hochhauser, D; Salomoni, P; (2017) mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism. Cell Death and Differentiation , 24 (6) pp. 1045-1062. 10.1038/cdd.2017.41. Green open access
file

Laskaratos, F-M; Rombouts, K; Caplin, M; Toumpanakis, C; Thirlwell, C; Mandair, D; (2017) Neuroendocrine tumors and fibrosis: An unsolved mystery? Cancer , 123 (24) pp. 4770-4790. 10.1002/cncr.31079. Green open access
file

Lawler, K; Papouli, E; Naceur-Lombardelli, C; Mera, A; Ougham, K; Tutt, A; Kimbung, S; ... Purushotham, A; + view all (2017) Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study. Breast Cancer Research , 19 , Article 113. 10.1186/s13058-017-0881-y. Green open access
file

Liebert, A; López, S; Jones, BL; Montalva, N; Gerbault, P; Lau, W; Thomas, MG; ... Swallow, DM; + view all (2017) World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection. Human Genetics 10.1007/s00439-017-1847-y. (In press). Green open access
file

Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; Rowan, A; Wong, YNS; ... Swanton, C; + view all (2017) Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters. Annals of Oncology , 28 (10) pp. 2472-2480. 10.1093/annonc/mdx355. Green open access
file

Lopez-Garcia, C; Sansregret, L; Domingo, E; McGranahan, N; Hobor, S; Birkbak, NJ; Horswell, S; ... Swanton, C; + view all (2017) BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer. Cancer Cell , 31 (1) pp. 79-93. 10.1016/j.ccell.2016.11.001. Green open access
file

López, S; Thomas, MG; van Dorp, L; Ansari-Pour, N; Stewart, S; Jones, AL; Jelinek, E; ... Hellenthal, G; + view all (2017) The Genetic Legacy of Zoroastrianism in Iran and India: Insights into Population Structure, Gene Flow, and Selection. American Journal of Human Genetics , 101 (3) pp. 353-368. 10.1016/j.ajhg.2017.07.013. Green open access
file

M

Maley, CC; Aktipis, A; Graham, TA; Sottoriva, A; Boddy, AM; Janiszewska, M; Silva, AS; ... Shibata, D; + view all (2017) Classifying the evolutionary and ecological features of neoplasms. Nature Reviews Cancer , 17 (10) pp. 605-619. 10.1038/nrc.2017.69. Green open access
file

Marabelle, A; Baurain, J-F; Awada, A; Kristeleit, RS; Jossang, D-E; Jebsen, N-L; Loirat, D; ... Spicer, J; + view all (2017) LTX‐315, an oncolytic peptide converts "cold" tumors to "hot" in a majority of patients with advanced cancer: results from an ongoing phase I study. Presented at: 32nd Annual Meeting and Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2017): Part Two, National Harbor, Maryland, USA. Green open access
file

Marchetti, C; Kristeleit, R; McCormack, M; Mould, T; Olaitan, A; Widschwendter, M; MacDonald, N; (2017) Outcome of patients with advanced ovarian cancer who do not undergo debulking surgery: A single institution retrospective review. Gynecologic Oncology , 144 (1) pp. 57-60. 10.1016/j.ygyno.2016.11.001. Green open access
file

Mardakheh, FK; Sailem, HZ; Kümper, S; Tape, CJ; McCully, RR; Paul, A; Anjomani-Virmouni, S; ... Bakal, C; + view all (2017) Proteomics profiling of interactome dynamics by colocalisation analysis (COLA). Molecular BioSystems , 13 (1) pp. 92-105. 10.1039/c6mb00701e. Green open access
filefilefile

Marth, C; Vergote, I; Scambia, G; Oberaigner, W; Clamp, A; Berger, R; Kurzeder, C; ... Bach, BA; + view all (2017) ENGOT-ov-6/TRINOVA-2: Randomised, double-blind, phase 3 study of pegylated liposomal doxorubicin plus trebananib or placebo in women with recurrent partially platinum-sensitive or resistant ovarian cancer. European Journal of Cancer , 70 pp. 111-121. 10.1016/j.ejca.2016.09.004. Green open access
file

Martin, L-A; Ribas, R; Simigdala, N; Schuster, E; Pancholi, S; Tenev, T; Gellert, P; ... Dowsett, M; + view all (2017) Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance. Nature Communications , 8 , Article 1865. 10.1038/s41467-017-01864-y. Green open access
file

Mason, MD; Clarke, NW; James, ND; Dearnaley, DP; Spears, MR; Ritchie, AWS; Attard, G; ... STAMPEDE Investigators, .; + view all (2017) Adding Celecoxib With or Without Zoledronic Acid for Hormone-Naïve Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial. Journal of Clincal Oncology , 35 (14) pp. 1530-1541. 10.1200/JCO.2016.69.0677. Green open access
file

Massard, C; Mateo, J; Loriot, Y; Pezaro, C; Albiges, L; Mehra, N; Varga, A; ... de Bono, J; + view all (2017) Phase I/II trial of cabazitaxel plus abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel and abiraterone. Annals of Oncology , 28 (1) pp. 90-95. 10.1093/annonc/mdw441. Green open access
filefile

Mateo, J; Ganji, G; Lemech, C; Burris, HA; Han, S-W; Swales, K; Decordova, S; ... Arkenau, H-T; + view all (2017) A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors. Clinical Cancer Research , 23 (19) pp. 5981-5992. 10.1158/1078-0432.CCR-17-0725. Green open access
file

Maughan, EF; Butler, CR; Crowley, C; Teoh, GZ; Hondt, MD; Hamilton, NJ; Hynds, RE; ... Elliott, MJ; + view all (2017) A comparison of tracheal scaffold strategies for pediatric transplantation in a rabbit model. The Laryngoscope , 127 (12) E449-E457. 10.1002/lary.26611. Green open access
file

Maughan, EF; Hynds, RE; Proctor, TJ; Janes, SM; Elliott, M; Birchall, MA; Lowdell, MW; (2017) Autologous Cell Seeding in Tracheal Tissue Engineering. Current Stem Cell Reports , 3 (4) pp. 279-289. 10.1007/s40778-017-0108-2. Green open access
file

McDaniel, AS; Ferraldeschi, R; Krupa, R; Landers, M; Graf, R; Louw, J; Jendrisak, A; ... Attard, G; + view all (2017) Phenotypic diversity of circulating tumour cells in patients with metastatic castration-resistant prostate cancer. BJU International , 120 (5B) E30-E44. 10.1111/bju.13631. Green open access
file

McGranahan, N; Rosenthal, R; Hiley, CT; Rowan, AJ; Watkins, TBK; Wilson, GA; Birkbak, NJ; ... Swanton, C; + view all (2017) Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. Cell 10.1016/j.cell.2017.10.001. (In press). Green open access
file

McGranahan, N; Swanton, C; (2017) Cancer Evolution Constrained by the Immune Microenvironment. CELL , 170 (5) pp. 825-827. 10.1016/j.cell.2017.08.012. Green open access
file

McGranahan, N; Swanton, C; (2017) Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future. Cell , 168 (4) pp. 613-628. 10.1016/j.cell.2017.01.018. Green open access
file

McNamara, MG; Bridgewater, J; Lopes, A; Wasan, H; Malka, D; Jensen, LH; Okusaka, T; ... Valle, JW; + view all (2017) Systemic therapy in younger and elderly patients with advanced biliary cancer: sub-analysis of ABC-02 and twelve other prospective trials. BMC Cancer , 17 , Article 262. 10.1186/s12885-017-3266-9. Green open access
file

Mehanna, HM; Sen, M; Chester, JD; Sanghera, P; Paleri, V; Gaunt, P; Babrah, J; ... Forster, MD; + view all (2017) Phase III randomised controlled trial (RCT) comparing alternative regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer (CompARE). Presented at: 53rd Annual Clinical Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Mesquita, B; Rothwell, DG; Burt, DJ; Chemi, F; Fernandez-Gutierrez, F; Slane-Tan, D; Antonello, J; ... Brady, G; + view all (2017) Molecular analysis of single circulating tumour cells following long-term storage of clinical samples. Molecular Oncology , 11 (12) pp. 1687-1697. 10.1002/1878-0261.12113. Green open access
file

Meyer, T; Fox, R; Ma, YT; Ross, PJ; James, MW; Sturgess, R; Stubbs, C; ... Palmer, DH; + view all (2017) Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial. The Lancet Gastroenterology and Hepatology , 2 (8) pp. 565-575. 10.1016/S2468-1253(17)30156-5. Green open access
file

Meyer, T; Palmer, DH; Cheng, A-L; Hocke, J; Loembé, A-B; Yen, C-J; (2017) mRECIST to predict survival in advanced hepatocellular carcinoma: Analysis of two randomised phase II trials comparing nintedanib vs sorafenib. Liver International , 37 (7) pp. 1047-1055. 10.1111/liv.13359. Green open access
file

Milani, A; Kristeleit, R; McCormack, M; Raja, F; Luvero, D; Widschwendter, M; MacDonald, N; ... Ledermann, JA; + view all (2017) Switching from standard to dose-dense chemotherapy in front-line treatment of advanced ovarian cancer: a retrospective study of feasibility and efficacy. ESMO Open , 1 (6) , Article e000117. 10.1136/esmoopen-2016-000117. Green open access
file

Miller, R; Devlin, M-J; Brown, NF; Grunewald, T; McCormack, M; Lockley, M; Ledermann, JA; ... Kristeleit, RS; + view all (2017) Outcome of patients with advanced endometrial and cervical cancer treated in a phase 1 unit. Presented at: 2017 Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL, USA. Green open access
file

Miller, RE; Devlin, M; Brown, N; Woo, K; Grunewald, T; Speirs, A; Mitchison, M; ... Kristeleit, R; + view all (2017) Guidance by molecular selection improves the outcome of early phase treatment for gynecological (GYN) cancers. Presented at: AACR Annual Meeting 2017, Washington, D.C., USA. Green open access
file

Moniz, LS; Surinova, S; Ghazaly, E; Velasco, LG; Haider, S; Rodriguez-Prados, JC; Berenjeno, IM; ... Vanhaesebroeck, B; + view all (2017) Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate. Scientific Reports , 7 (39985) 10.1038/srep39985. Green open access
file

Montgomery, HE; Haines, A; Marlow, N; Pearson, G; Mythen, MG; Grocott, MPW; Swanton, C; (2017) The future of UK healthcare: problems and potential solutions to a system in crisis. [Review]. Annals of Oncology , 28 (8) pp. 1751-1755. 10.1093/annonc/mdx136. Green open access
file

Morrissy, AS; Cavalli, FMG; Remke, M; Ramaswamy, V; Shih, DJH; Holgado, BL; Farooq, H; ... Taylor, MD; + view all (2017) Spatial heterogeneity in medulloblastoma. Nature Genetics , 49 (5) pp. 780-788. 10.1038/ng.3838. Green open access
file

Moschetta, M; Mak, G; Hauser, J; Davies, C; Uccello, M; Arkenau, HT; (2017) Dabrafenib and trametinib activity in a patient with BRAF V600E mutated and microsatellite instability high (MSI-H) metastatic endometrial cancer. Experimental Hematology & Oncology , 6 (1) , Article 1. 10.1186/s40164-016-0061-2. Green open access
file

Mukherjee, S; Hurt, CN; Gwynne, S; Sebag-Montefiore, D; Radhakrishna, G; Gollins, S; Hawkins, M; ... Crosby, T; + view all (2017) NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma. European Journal of Cancer , 74 pp. 38-46. 10.1016/j.ejca.2016.11.031. Green open access
file

N

Naxerova, K; Reiter, JG; Brachtel, E; Lennerz, JK; van de Wetering, M; Rowan, A; Cai, T; ... Jain, RK; + view all (2017) Origins of lymphatic and distant metastases in human colorectal cancer. Science , 357 (6346) pp. 55-60. 10.1126/science.aai8515. Green open access
file

Neoptolemos, JP; Palmer, DH; Ghaneh, P; Psarelli, EE; Valle, JW; Halloran, CM; Faluyi, O; ... European Study Group for Pancreatic Cancer, .; + view all (2017) Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet , 389 (10073) pp. 1011-1024. 10.1016/S0140-6736(16)32409-6. Green open access
file

Ngwenya, N; Kenten, C; Jones, L; Gibson, F; Pearce, S; Flatley, M; Hough, R; ... Whelan, J; + view all (2017) Experiences and Preferences for End-of-Life Care for Young Adults with Cancer and Their Informal Carers: A Narrative Synthesis. Journal of Adolescent and Young Adult Oncology , 6 (2) pp. 200-212. 10.1089/jayao.2016.0055. Green open access
file

O

Oakes, T; Heather, JM; Best, K; Byng-Maddick, R; Husovsky, C; Ismail, M; Joshi, K; ... Chain, B; + view all (2017) Quantitative Characterization of the T Cell Receptor Repertoire of Naive and Memory subsets Using an Integrated experimental and Computational Pipeline Which Is Robust, economical, and Versatile. Frontiers in Immunology , 8 , Article 1267. 10.3389/fimmu.2017.01267. Green open access
file

Oakes, T; Popple, AL; Williams, J; Best, K; Heather, JM; Ismail, M; Maxwell, G; ... Chain, B; + view all (2017) The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors. Frontiers in Immunology , 8 , Article 162. 10.3389/fimmu.2017.00162. Green open access
file

Oaknin, A; Oza, A; Tinker, A; Ray-Coquard, I; Coleman, R; O'Malley, D; Shapira-Frommer, R; ... Kristeleit, RS; + view all (2017) Integrated efficacy and safety analysis of the poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with high-grade ovarian carcinoma (HGOC). In: ECCO: 2017 European Cancer Congress. Abstract Book. (pp. S95-S95). Elsevier Green open access
file

Olmedo Garcia, ME; Forster, M; Calvo, E; Moreno, V; Lopez Criado, MP; Lopez-Vilarino de Ramos, JA; Kahatt, C; ... Soto-Matos, A; + view all (2017) Activity of lurbinectedin as single agent and in combination in patients with advanced small cell lung cancer (SCLC). Presented at: 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, Spain.

Ortiz-Zapater, E; Lee, RW; Owen, W; Weitsman, G; Fruhwirth, G; Dunn, RG; Neat, MJ; ... Santis, G; + view all (2017) MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition. PLoS ONE , 12 (1) , Article e0170798. 10.1371/journal.pone.0170798. Green open access
file

Oza, AM; Lorusso, D; Oaknin, A; Safra, T; Swisher, ER; Bondarenko, I; Huzarski, T; ... Kristeleit, RS; + view all (2017) ARIEL4: An international, multicenter randomized phase 3 study of the PARP inhibitor rucaparib vs chemotherapy in germline or somatic BRCA1- or BRCA2-mutated, relapsed, high-grade ovarian carcinoma. Presented at: ESMO 2017 Congress, Madrid, Spain.

Oza, AM; Tinker, AV; Oaknin, A; Shapira-Frommer, R; McNeish, IA; Swisher, EM; Ray-Coquard, I; ... Kristeleit, RS; + view all (2017) Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2. Gynecologic Oncology , 147 (2) pp. 267-275. 10.1016/j.ygyno.2017.08.022. Green open access
file

P

Pallett, LJ; Davies, J; Colbeck, EJ; Robertson, F; Hansi, N; Easom, NJW; Burton, AR; ... Maini, MK; + view all (2017) IL-2(high) tissue-resident T cells in the human liver: Sentinels for hepatotropic infection. Journal of Experimental Medicine , 214 (6) pp. 1567-1580. 10.1084/jem.20162115. Green open access
file

Patel, D; Hamoudi, R; Khan, S; Allen, D; Edeline, J; Bridgewater, J; Rodriguez-Justo, M; (2017) Genetic and Epigenetic Alterations in Biliary Tree Cancers: Combined FISH, IHC and NGS Approach. Presented at: 10th Joint Meeting of the British-Division of the International-Academy-of-Pathology and the Pathological-Society-of-Great-Britain-and-Ireland, Queens Univ Belfast, Ctr Canc Res & Cell Biol, No Ireland Mol Pathol Lab, Belfast, IRELAND.

Patel, D; Hamoudi, R; Khan, S; Puccio, I; Bridgewater, J; Edeline, J; Rodriguez- Justo, M; (2017) Combined FISH, IHC and NGS Identifies New Therapeutic Targets in Cholangiocarcinomas. Presented at: UNSPECIFIED.

Patel, D; Hamoudi, R; Khan, S; Puccio, I; Edeline, J; Bridgewater, J; Rodriguez-Justo, M; (2017) Combined FISH, IHC and NGS Identifies New Therapeutic Targets in Cholangiocarcinomas. Presented at: 106th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), San Antonio, TX.

Patel, D; Hamoudi, R; Khan, S; Puccio, I; Edeline, J; Bridgewater, J; Rodriguez-Justo, M; (2017) Combined FISH, IHC and NGS Identifies New Therapeutic Targets in Cholangiocarcinomas. Presented at: 106th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), San Antonio, TX.

Paz-Ares, L; Forster, M; Boni, V; Szyldergemajn, S; Corral, J; Turnbull, S; Cubillo, A; ... Calvo, E; + view all (2017) Phase I clinical and pharmacokinetic study of PM01183 (a tetrahydroisoquinoline, Lurbinectedin) in combination with gemcitabine in patients with advanced solid tumors. Investigational New Drugs , 35 (2) pp. 198-206. 10.1007/s10637-016-0410-3. Green open access
file

Pett, L; Kiakos, K; Satam, V; Patil, P; Laughlin-Toth, S; Gregory, M; Bowerman, M; ... Hartley, JA; + view all (2017) Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms , 1860 (5) pp. 617-629. 10.1016/j.bbagrm.2016.10.005. Green open access
file

Pinder, SE; Campbell, AF; Bartlett, JMS; Marshall, A; Allen, D; Falzon, M; Dunn, JA; ... Stein, RC; + view all (2017) Discrepancies in central review re-testing of patients with ER-positive and HER2-negative breast cancer in the OPTIMA prelim randomised clinical trial. British Journal of Cancer , 116 (7) pp. 859-863. 10.1038/bjc.2017.28. Green open access
file

Primrose, JN; Fox, R; Palmer, DH; Prasad, R; Mirza, D; Anthoney, DA; Corrie, P; ... Bridgewater, JA; + view all (2017) Adjuvant capecitabine for biliary tract cancer: The BILCAP randomized study. Presented at: 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Pugh, S; Bridgewater, J; Finch-Jones, M; Rees, M; O'Reilly, D; Peterson, M; Davidson, B; ... Primrose, J; + view all (2017) Surgical quality and the impact of liver resection on outcome in the new EPOC study. Presented at: 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, SPAIN.

Pugh, S; Thiébaut, R; Bridgewater, J; Grisoni, ML; Moutasim, K; Rousseau, F; Thomas, GJ; ... Laurent-Puig, P; + view all (2017) Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: A post-hoc analysis of the New EPOC trial. Oncotarget , 8 (55) pp. 93856-93866. 10.18632/oncotarget.21291. Green open access
file

R

Ralli, GP; McGowan, DR; Chappell, MA; Sharma, RA; Higgins, GS; Fenwick, JD; (2017) 4D-PET reconstruction of dynamic non-small cell lung cancer [18-F]-FMISO-PET data using adaptive-knot cubic B-splines. In: 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017). (pp. pp. 1189-1192). IEEE Green open access
file

Robillard, L; Nguyen, M; Loehr, A; Orsulic, S; Kristeleit, RS; Lin, K; Raponi, M; ... Simmons, AD; + view all (2017) Preclinical evaluation of the PARP inhibitor rucaparib in combination with PD-1 and PD-L1 inhibition in a syngeneic BRCA1 mutant ovarian cancer model. Presented at: AACR Annual Meeting 2017, Washington, D.C., USA. Green open access
file

Robinson, E; Nunes, JPM; Vassileva, V; Maruani, A; Nogueira, JCF; Smith, MEB; Pedley, RB; ... Chudasama, V; + view all (2017) Pyridazinediones deliver potent, stable, targeted and efficacious antibody–drug conjugates (ADCs) with a controlled loading of 4 drugs per antibody. RSC Advances , 7 (15) pp. 9073-9077. 10.1039/C7RA00788D. Green open access
file

Rosenthal, R; McGranahan, N; Herrero, J; Swanton, C; (2017) Deciphering Genetic Intratumor Heterogeneity and Its Impact on Cancer Evolution. Annual Review of Cancer Biology , 1 pp. 223-240. 10.1146/annurev-cancerbio-042516-011348. Green open access
filefile

Rossello, X; Riquelme, JA; He, Z; Taferner, S; Vanhaesebroeck, B; Davidson, SM; Yellon, DM; (2017) The role of PI3Kα isoform in cardioprotection. Basic Research in Cardiology , 112 , Article 66. 10.1007/s00395-017-0657-7. Green open access
file

S

Sangro, B; Martínez-Urbistondo, D; Bester, L; Bilbao, JI; Coldwell, DM; Flamen, P; Kennedy, A; ... Sharma, RA; + view all (2017) Prevention and treatment of complications of selective internal radiation therapy: expert guidance and systematic review. Hepatology , 66 (3) pp. 969-982. 10.1002/hep.29207. Green open access
file

Sangro, B; Melero, I; Yau, T; Hsu, C; Kudo, M; Kim, T-Y; Choo, S-P; ... El-Khoueiry, AB; + view all (2017) Nivolumab in Sorafenib-Naive and -Experienced Patients With Advanced Hepatocellular Carcinoma (HCC): Survival, Hepatic Safety, and Biomarker Assessments in CheckMate 040. Presented at: 68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Washington, DC.

Sangro, B; Yau, T; Hsu, C; Kudo, M; Crocenzi, TS; Choo, S-P; Meyer, T; ... Trojan, J; + view all (2017) Nivolumab in sorafenib-experienced patients with advanced hepatocellular carcinoma (HCC) with or without chronic viral hepatitis: CheckMate 040 study. Presented at: International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Amsterdam, NETHERLANDS.

Sansregret, L; Patterson, JO; Dewhurst, S; Lopez-Garcia, C; Koch, A; McGranahan, N; Chao, WCH; ... Swanton, C; + view all (2017) APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability. Cancer Discovery , 7 (2) pp. 218-233. 10.1158/2159-8290.CD-16-0645. Green open access
file

Sansregret, L; Swanton, C; (2017) The Role of Aneuploidy in Cancer Evolution. Cold Spring Harbor Perspectives in Medicine , 7 (1) , Article a028373. 10.1101/cshperspect.a028373. Green open access
file

Schmid, P; Forster, MD; Summers, YJ; Good, J; Sarker, S-J; Lim, L; Mousa, K; (2017) A study of vistusertib in combination with selumetinib in patients with advanced cancers: TORCMEK phase Ib results. Presented at: 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, Spain.

Schöffski, P; Wozniak, A; Casali, PG; Rutkowski, P; Blay, J-Y; Lindner, LH; Strauss, SJ; ... Bauer, S; + view all (2017) Activity and safety of crizotinib in patients with advanced clear cell sarcoma with MET alterations. European Organization for Research and Treatment of Cancer phase 2 trial 90101 "CREATE". Annals of Oncology , 28 (12) pp. 3000-3008. 10.1093/annonc/mdx527. Green open access
file

Schöneberg, J; Lehmann, M; Ullrich, A; Posor, Y; Lo, W-T; Lichtner, G; Schmoranzer, J; ... Noé, F; + view all (2017) Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission. Nature Communications , 8 , Article 15873. 10.1038/ncomms15873. Green open access
file

Seddon, B; Strauss, SJ; Whelan, J; Leahy, M; Woll, PJ; Cowie, F; Rothermundt, C; ... Beare, S; + view all (2017) Gemcitabine and docetaxel versus doxorubicin as first-line treatment in previously untreated advanced unresectable or metastatic soft-tissue sarcomas (GeDDiS): a randomised controlled phase 3 trial. The Lancet Oncology , 18 (10) pp. 1397-1410. 10.1016/S1470-2045(17)30622-8. Green open access
file

Singer, R; Campbell, P; Fernandes, C; Statham, P; Hochhauser, D; Bridgewater, J; (2017) Time to endoscopic intervention in patients with upper gastrointestinal patients can be improved with pathway provision. BMC Cancer , 17 , Article 365. 10.1186/s12885-017-3335-0. Green open access
file

Skoglund, P; Thompson, JC; Prendergast, ME; Mittnik, A; Sirak, K; Hajdinjak, M; Salie, T; ... Reich, D; + view all (2017) Reconstructing Prehistoric African Population Structure. Cell , 171 (1) 59-71.e21. 10.1016/j.cell.2017.08.049. Green open access
file

Spicer, J; Irshad, S; Ang, JE; Enting, D; Kristeleit, RS; Uttenreuther-Fischer, M; Pemberton, K; ... De Bono, J; + view all (2017) A phase I study of afatinib combined with paclitaxel and bevacizumab in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology , 79 (1) pp. 17-27. 10.1007/s00280-016-3189-1. Green open access
file

Spicer, JF; Baurain, JF; Awada, A; Kristeleit, RS; Jossang, DE; Marabelle, A; Loirat, D; ... Brunsvig, P; + view all (2017) LTX-315, an oncolytic peptide, to convert immunogenically 'cold' tumors to 'hot' in patients with advanced or metastatic tumours: Results from an ongoing phase I study. Presented at: American Society of Clinical Oncology Annual Meeting 2017, Chicago, IL, USA. (In press). Green open access
file

Suh, Y-E; Lawler, K; Henley-Smith, R; Pike, L; Leek, R; Barrington, S; Odell, EW; ... Tavassoli, M; + view all (2017) Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma. British Journal of Cancer , 116 (8) pp. 1057-1064. 10.1038/bjc.2017.66. Green open access
file

Swisher, E; Harrell, MI; Lin, KK; Scott, CL; Goble, S; Oza, A; Coleman, RL; ... Kaufmann, S; + view all (2017) BRCA1 and RAD51C Promoter Hypermethylation Confer Sensitivity to PARP Inhibitors in Patients with Platinum Sensitive Ovarian Carcinoma. Clinical Cancer Research , 23 (11 Suppl) 10.1158/1557-3265.OVCASYMP16-AP28. Green open access
file

Swisher, EM; Lin, KK; Oza, AM; Scott, CL; Giordano, H; Sun, J; Konecny, GE; ... McNeish, IA; + view all (2017) Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial. Lancet Oncology , 18 (1) pp. 75-87. 10.1016/S1470-2045(16)30559-9. Green open access
file

T

Taieb, J; Kourie, HR; Emile, J-F; Le Malicot, K; Balogoun, R; Tabernero, J; Mini, E; ... Pan-European Trials in Alimentary Tract Cancer (PETACC)-8 Invest, ; + view all (2017) Association of Prognostic Value of Primary Tumor Location in Stage III Colon Cancer With RAS and BRAF Mutational Status. JAMA Oncology 10.1001/jamaoncol.2017.3695. (In press).

Tape, CJ; (2017) The Heterocellular Emergence of Colorectal Cancer. Trends Cancer , 3 (2) pp. 79-88. 10.1016/j.trecan.2016.12.004. Green open access
file

Taylor, SA; Mallett, S; Miles, A; Beare, S; Bhatnagar, G; Bridgewater, J; Glynne-Jones, R; ... Halligan, S; + view all (2017) Streamlining staging of lung and colorectal cancer with whole body MRI; study protocols for two multicentre, non-randomised, single-arm, prospective diagnostic accuracy studies (Streamline C and Streamline L). BMC Cancer , 17 , Article 299. 10.1186/s12885-017-3281-x. Green open access
file

Thistlethwaite, FC; Gilham, DE; Guest, RD; Rothwell, DG; Pillai, M; Burt, DJ; Byatte, AJ; ... Hawkins, RE; + view all (2017) The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity. Cancer Immunology, Immunotherapy 10.1007/s00262-017-2034-7. (In press). Green open access
file

Tomas, A; Jones, S; Vaughan, SO; Hochhauser, D; Futter, CE; (2017) Stress-specific p38 MAP kinase activation is sufficient to drive EGF receptor endocytosis but not nuclear translocation. Journal of Cell Science , 130 (15) pp. 2481-2490. 10.1242/jcs.202358. Green open access
file

Trojan, J; Crocenzi, TS; El-Khoueiry, AB; Yau, T; Melero, I; Sangro, B; Kudo, M; ... Welling, TH; + view all (2017) Nivolumab in sorafenib-naive and - experienced patients with advanced hepatocellular carcinoma (HCC): checkMate 040 study. Presented at: UNSPECIFIED.

Turajlic, S; Litchfield, K; Xu, H; Rosenthal, R; McGranahan, N; Reading, JL; Wong, YNS; ... Swanton, C; + view all (2017) Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis. The Lancet Oncology , 18 (8) pp. 1009-1021. 10.1016/S1470-2045(17)30516-8. Green open access
filefile

U

Uccello, M; Kushnir, M; Mak, G; Henriquez, CM; Abbosh, C; Papadatos-Pastos, D; Newsom-Davis, T; ... Arkenau, H-T; + view all (2017) Circulating tumour DNA (ctDNA) in the clinical management of patients (pts) with advanced non-small cell lung cancer (NSCLC): A single centre experience. Presented at: 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, Spain.

V

Valet, C; Levade, M; Chicanne, G; Bilanges, B; Cabou, C; Viaud, J; Gratacap, M-P; ... Severin, S; + view all (2017) A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth. Blood , 130 (18) pp. 2032-2042. 10.1182/blood-2017-04-781641. Green open access
file

Vargas, FA; Furness, AJS; Solomon, I; Joshi, K; Mekkaoui, L; Lesko, MH; Rota, EM; ... Quezada, SA; + view all (2017) Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors. Immunity , 46 (4) pp. 577-586. 10.1016/j.immuni.2017.03.013. Green open access
file

Varrault, A; Dantec, C; Le Digarcher, A; Chotard, L; Bilanges, B; Parrinello, H; Dubois, E; ... Journot, L; + view all (2017) Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network. Nucleic Acids Research , 45 (18) pp. 10466-10480. 10.1093/nar/gkx672. Green open access
file

Vergote, I; Dean, E; Lassen, U; de Bono, J; Drew, Y; Machiels, J-P; Nielsen, D; ... Hong, DS; + view all (2017) A phase IIa study of tisotumab vedotin (HuMax (R)-TF-ADC) in patients with relapsed, recurrent and/or metastatic cervical cancer. Presented at: 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, Spain.

Virdee, PS; Moschandreas, J; Gebski, V; Love, SB; Francis, EA; Wasan, HS; van Hazel, G; ... Sharma, RA; + view all (2017) Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer. JMIR Res Protoc , 6 (3) , Article e43. 10.2196/resprot.7201. Green open access
file

Volpi, D; Tullis, IDC; Barber, PR; Augustyniak, EM; Smart, SC; Vallis, KA; Vojnovic, B; (2017) Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery. Biomedical Optics Express , 8 (7) pp. 3232-3247. 10.1364/BOE.8.003232. Green open access
file

W

Waked, I; Berhane, S; Toyoda, H; Chan, SL; Stern, N; Palmer, D; Tada, T; ... Johnson, PJ; + view all (2017) Transarterial chemo-embolisation of hepatocellular carcinoma: impact of liver function and vascular invasion. British Journal of Cancer , 116 pp. 448-454. 10.1038/bjc.2016.423. Green open access
file

Wasan, HS; Gibbs, P; Sharma, NK; Taieb, J; Heinemann, V; Ricke, J; Peeters, M; ... Sharma, RA; + view all (2017) First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials. The Lancet Oncology 10.1016/S1470-2045(17)30457-6. (In press). Green open access
file

Weitsman, G; Mitchell, NJ; Evans, R; Cheung, A; Kalber, TL; Bofinger, R; Fruhwirth, GO; ... Ng, T; + view all (2017) Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor. Oncogene , 36 pp. 3618-3628. 10.1038/onc.2016.522. Green open access
file

Winter, H; Kaisaki, P; Harvey, J; Carter, R; Sharma, RA; Tayor, JC; Mccullagh, J; (2017) Circulating tumour DNA and oncometabolites in patients with intrahepatic cholangiocarcinoma. Presented at: 3rd Molecular Analysis for Personalised Therapy (MAP) Conference, Zurich, SWITZERLAND.

Wirapati, P; Pomella, V; Vandenbosch, B; Kerr, P; Maiello, E; Jeffery, GM; Curca, R-OD; ... Tejpar, S; + view all (2017) Velour trial biomarkers update: Impact of RAS, BRAF, and sidedness on aflibercept activity. Presented at: 53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Wong, YNS; Joshi, K; Khetrapal, P; Ismail, M; Linares, J; Akarca, AU; Reading, JL; ... Quezada, S; + view all (2017) Urine-derived lymphocytes (UDLs) as a non-invasive surrogate marker of tumour infiltrating lymphocytes (TILs) in patients with muscle invasive bladder cancer (MIBC). Presented at: 42nd European-Society-for-Medical-Oncology Congress (ESMO), Madrid, SPAIN.

Wong, YNS; Joshi, K; Pule, M; Peggs, KS; Swanton, C; Quezada, SA; Linch, M; (2017) Evolving adoptive cellular therapies in urological malignancies. Lancet Oncology , 18 (6) E341-E353. 10.1016/S1470-2045(17)30327-3. Green open access
file

Wood, G; Grenader, T; Nash, S; Adams, R; Kaplan, R; Fisher, D; Maughan, T; (2017) Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study. Anti-Cancer Drugs , 28 (5) pp. 546-550. 10.1097/CAD.0000000000000488. Green open access
file

Wulaningsih, W; Holmberg, L; Abeler-Dörner, L; Ng, T; Rohrmann, S; Van Hemelrijck, M; (2017) Correction: Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women. PLoS One , 11 (8) , Article e0161418. 10.1371/journal.pone.0161418. Green open access
file

Y

Yip, K; Conibear, J; Woolf, D; Tarver, K; Willis, B; Hall, S; Sun, F; ... Gilligan, D; + view all (2017) A retrospective multicentre audit of outcome among patients with anaplastic lymphoma kinase (ALK) gene rearrangement positive non-small cell lung cancer (NSCLC) who have been treated with crizotinib in England. Presented at: UNSPECIFIED.

Z

Zammarchi, F; Corbett, S; Havenith, K; Janghra, N; Kiakos, K; Marafioti, T; Williams, DG; ... van Berkel, PH; + view all (2017) Characterization of the mechanism of action, pharmacodynamics and preclinical safety of ADCT-402, a pyrrolobenzodiazepine (PBD) dimer-containing antibody-drug conjugate (ADC) targeting CD19-expressing hematological malignancies. Presented at: Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC.

This list was generated on Sun Jul 21 04:57:57 2019 BST.