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Number of items: 149.

A

Adams, RA; Brown, E; Brown, L; Butler, R; Falk, S; Fisher, D; Kaplan, R; ... Maughan, T; + view all (2016) FOCUS4-D: Results from a randomised, placebo controlled trial (RCT) of AZD8931 (an inhibitor of signalling by HER1, 2, and 3) in patients (pts) with advanced or metastatic colorectal cancer (aCRC) in tumours that are wildtype (wt) for BRAF, PIK3CA, KRAS & NRAS. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Ahmed, K; Kyte, D; Keeley, T; Efficace, F; Armes, J; Brown, JM; Calman, L; ... Calvert, M; + view all (2016) Systematic evaluation of patient-reported outcome (PRO) protocol content and reporting in UK cancer clinical trials: the EPiC study protocol. BMJ Open , 6 (9) , Article e012863. 10.1136/bmjopen-2016-012863. Green open access
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Alliouachene, S; Bilanges, B; Chaussade, C; Pearce, W; Foukas, LC; Scudamore, CL; Moniz, LS; (2016) Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice. Diabetologia , 59 (7) pp. 1503-1512. 10.1007/s00125-016-3963-y. Green open access
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Alrifai, D; ngan, S; shipway, D; (2016) Surgery for Upper Gastrointestinal Cancer in a Morbidly Obese Patient with Diabetes and Renal Impairment. In: Problem Solving in Older Cancer Patients A Case Study Based Reference and Learning Resource. Evidence-based Networks Ltd

Ang, JE; Pandher, R; Ang, JC; Asad, YJ; Henley, A; Valenti, M; Box, G; ... Raynaud, FI; + view all (2016) Plasma metabolomic changes following PI3K inhibition as pharmacodynamic biomarkers: preclinical discovery to Phase I trial evaluation. Molecular Cancer Therapeutics , 15 (6) pp. 1412-1424. 10.1158/1535-7163.MCT-15-0815. Green open access
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Anjos-Afonso, F; Loizou, JI; Bradburn, A; Kanu, N; Purewal, S; Da Costa, C; Bonnet, D; (2016) Perturbed hematopoiesis in mice lacking ATMIN. Blood , 128 (16) pp. 2017-2021. 10.1182/blood-2015-09-672980. Green open access
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Attard, G; Antonarakis, ES; (2016) Prostate cancer: AR aberrations and resistance to abiraterone or enzalutamide. Nature Reviews Urology , 13 (12) pp. 697-698. 10.1038/nrurol.2016.212. Green open access
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B

Barrett, JE; Siriwardana, PN; Singh, S; Kim, P; Hochhauser, D; Davidson, BR; Ng, T; (2016) PROBING THE EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR) SIGNALLING PATHWAY IN COLORECTAL LIVER METASTASES (CRLM). Presented at: UNSPECIFIED.

Bendell, JC; Patel, MR; Yoshida, K; Seraj, J; Weaver, R; Lemech, C; Todaro, TG; ... Arkenau, H-T; + view all (2016) Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors. Cancer Chemother Pharmacol , 77 (6) pp. 1275-1283. 10.1007/s00280-016-3031-9. Green open access
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Benson, AB; Kiss, I; Bridgewater, J; Eskens, FALM; Sasse, C; Vossen, S; Chen, J; ... Krivoshik, A; + view all (2016) BATON-CRC: A Phase II Randomized Trial Comparing Tivozanib Plus mFOLFOX6 with Bevacizumab Plus mFOLFOX6 in Stage IV Metastatic Colorectal Cancer. Clinical Cancer Research , 22 (20) pp. 5058-5067. 10.1158/1078-0432.CCR-15-3117. Green open access
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Bentham, RB; (2016) A bioinfomatic analysis of the role of mitochondrial biogenesis in human pathologies. Doctoral thesis , UCL (University College London). Green open access
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Bentzen, AK; Marquard, AM; Lyngaa, R; Saini, SK; Ramskov, S; Donia, M; Such, L; ... Hadrup, SR; + view all (2016) Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes. Nature Biotechnology , 34 (10) pp. 1037-1045. 10.1038/nbt.3662. Green open access
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Bridgewater, J; (2016) Adjuvant therapy for biliary tract cancer. Presented at: 3rd St. Gallen-International Gastrointestinal Cancer Conference on Primary Therapy of Early GI Cancer with International Treatment Consensus, St Gallen, SWITZERLAND.

Bridgewater, J; Lopes, A; Beare, S; Duggan, M; Lee, D; Ricamara, M; McEntee, D; ... Valle, JW; + view all (2016) A phase 1b study of Selumetinib in combination with Cisplatin and Gemcitabine in advanced or metastatic biliary tract cancer: the ABC-04 study. BMC Cancer , 16 (1) p. 153. 10.1186/s12885-016-2174-8. Green open access
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Broushaki, F; Thomas, MG; Link, V; López, S; van Dorp, L; Kirsanow, K; Hofmanová, Z; ... Burger, J; + view all (2016) Early Neolithic genomes from the eastern Fertile Crescent. Science , 353 (6298) pp. 499-503. 10.1126/science.aaf7943. Green open access
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Brown, N; McBain, C; Nash, S; Hopkins, K; Sanghera, P; Saran, F; Phillips, M; ... Mulholland, P; + view all (2016) Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma. PLoS ONE , 11 (5) 10.1371/journal.pone.0156369. Green open access
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C

Campbell, J; Ryan, CJ; Brough, R; Bajrami, I; Pemberton, HN; Chong, IY; Costa-Cabral, S; ... Lord, CJ; + view all (2016) Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell Reports , 14 (10) pp. 2490-2501. 10.1016/j.celrep.2016.02.023. Green open access
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Carter, T; Brown, N; Shaw, H; Chester, K; Cohn-Brown, D; Mulholland, P; (2016) SURVIVAL AND EFFICACY DATA FOR PATIENTS WITH GLIOBLASTOMA TREATED WITH IPILIMUMAB IN COMBINATION WITH BEVACIZUMAB. Presented at: 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale, AZ.

Carter, T; Mulholland, P; Chester, K; (2016) Antibody-targeted nanoparticles for cancer treatment. Immunotherapy , 8 (8) pp. 941-958. 10.2217/imt.16.11. Green open access
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Carter, T; Shawy, H; Cohn-Brown, D; Chester, K; Mulholland, P; (2016) Ipilimumab and Bevacizumab in Glioblastoma. Clinical Oncology , 28 (10) pp. 622-626. 10.1016/j.clon.2016.04.042. Green open access
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Castillo, SD; Tzouanacou, E; Zaw-Thin, M; Berenjeno, IM; Parker, VE; Chivite, I; Milà-Guasch, M; ... Vanhaesebroeck, B; + view all (2016) Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans. Science Translational Medicine , 8 (332) , Article 332ra43. 10.1126/scitranslmed.aad9982. Green open access
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Castillo, SD; Vanhaesebroeck, B; Sebire, NJ; (2016) Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies. The Journal of Pathology , 240 (4) pp. 387-396. 10.1002/path.4802. Green open access
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Chakravarthy, A; Henderson, S; Thirdborough, SM; Ottensmeier, CH; Su, X; Lechner, M; Feber, A; ... Fenton, TR; + view all (2016) Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx. Journal Of Clinical Oncology , 34 (34) pp. 4132-4141. 10.1200/JCO.2016.68.2955. Green open access
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Chen, X; Zhabyeyev, P; DesAulniers, J; Wang, X; Wang, F; Murray, AG; Kassiri, Z; ... Oudit, GY; + view all (2016) Distinctive Functions of PI3K beta in Endothelial Cells and Cardiomyocytes in Response to Myocardial Infarction: Complications for Targeting PI3K beta in Myocardial Infarction Treatment. Presented at: Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, New Orleans, LA.

Childs, A; Kirkwood, A; Edeline, J; Tu, VL; Watkins, J; Lamarca, A; Alrifai, D; ... Meyer, T; + view all (2016) Ki-67 index and response to chemotherapy in patients with neuroendocrine tumours. Endocrine-Related Cancer , 23 (7) pp. 563-570. 10.1530/ERC-16-0099. Green open access
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Childs, A; Vesely, C; Ensell, L; Lowe, H; Luong, TV; Caplin, ME; Toumpanakis, C; ... Meyer, T; + view all (2016) Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours. British Journal of Cancer , 115 (12) pp. 1540-1547. 10.1038/bjc.2016.377. Green open access
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Childs, A; Vesely, C; Ensell, L; Luong, T; Caplin, M; Toumpanakis, C; Thirlwell, C; ... Meyer, T; + view all (2016) Detection of SSTR2 and 5 Expression on Circulating Tumour Cells in Neuroendocrine Tumours. Presented at: 13th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, SPAIN.

Chung, R; Maulik, A; Hamarneh, A; Hochhauser, D; Hausenloy, DJ; Walker, JM; Yellon, DM; (2016) Effect of Remote Ischaemic Conditioning in ONCology patients undergoing chemotherapy: rationale and design of the ERIC-ONC study - a single-center, blinded, randomized controlled trial. Clinical Cardiology , 39 (2) pp. 72-82. 10.1002/clc.22507. Green open access
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Coulter, TI; Chandra, A; Bacon, CM; Babar, J; Curtis, J; Screaton, N; Goodlad, JR; ... Cant, AJ; + view all (2016) Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study. J Allergy Clin Immunol 10.1016/j.jaci.2016.06.021. Green open access
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Crowley, C; Klanrit, P; Butler, CR; Varanou, A; Platé, M; Hynds, RE; Chambers, RC; ... Janes, SM; + view all (2016) Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold. Biomaterials , 83 pp. 283-293. 10.1016/j.biomaterials.2016.01.005. Green open access
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D

Dangoor, A; Seddon, B; Gerrand, C; Grimer, R; Whelan, J; Judson, I; (2016) UK guidelines for the management of soft tissue sarcomas. Clinical Sarcoma Research , 6 , Article 20. 10.1186/s13569-016-0060-4. Green open access
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Dillon, M; Ellis, S; Grove, L; McLellan, L; Clack, G; Smith, S; Laude, J; ... Harrington, KJ; + view all (2016) PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours. Presented at: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Dirix, L; Swaisland, H; Verheul, HMW; Rottey, S; Leunen, K; Jerusalem, G; Rolfo, C; ... Plummer, R; + view all (2016) Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies. Clinical Therapeutics , 38 (10) pp. 2286-2299. 10.1016/j.clinthera.2016.08.010. Green open access
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Drummond, CJ; Esfandiari, A; Liu, J; Lu, X; Hutton, C; Jackson, J; Bennaceur, K; ... Lunec, J; + view all (2016) TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation. Oncotarget , 7 (29) pp. 46203-46218. 10.18632/oncotarget.10073. Green open access
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E

Edeline, J; Blanc, JF; Johnson, P; Campillo-Gimenez, B; Ross, P; Ma, YT; King, J; ... Meyer, T; + view all (2016) A multicentre comparison between Child Pugh and Albumin-Bilirubin scores in patients treated with sorafenib for Hepatocellular Carcinoma. Liver International , 36 (12) pp. 1821-1828. 10.1111/liv.13170. Green open access
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Esfandiari, A; Hawthorne, TA; Nakjang, S; Lunec, J; (2016) Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner. Molecular Cancer Therapeutics , 15 (3) pp. 379-391. 10.1158/1535-7163.MCT-15-0651. Green open access
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F

Feber, A; Worth, DC; Chakravarthy, A; de Winter, P; Shah, K; Arya, M; Saqib, M; ... Kelly, JD; + view all (2016) CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma. Cancer Research , 76 (16) pp. 4720-4727. 10.1158/0008-5472.CAN-15-3134. Green open access
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Ferolla, P; Brizzi, MP; Meyer, T; Mansoor, W; Mazieres, J; Cao, CD; Lena, H; ... Baudin, E; + view all (2016) Efficacy and safety of pasireotide LAR or everolimus alone, or in combination in patients with advanced carcinoids (NET) of the lung/thymus: Results from the randomized, phase 2 LUNA study. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Findlay, JM; Castro-Giner, F; Makino, S; Rayner, E; Kartsonaki, C; Cross, W; Kovac, M; ... Tomlinson, I; + view all (2016) Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy. Nature Communications , 7 , Article 11111. 10.1038/ncomms11111. Green open access
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Flores-Borja, F; Irshad, S; Gordon, P; Wong, F; Sheriff, I; Tutt, A; Ng, T; (2016) Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment. Journal of Immunology Research , Article 7803091. 10.1155/2016/7803091. Green open access
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Flynn, MJ; (2016) Mechanistic and pharmacodynamic studies of ADCT-301, an Antibody Drug Conjugate targeting CD25-expressing haematological malignancies. Doctoral thesis , UCL (University College London).

Flynn, MJ; Zammarchi, F; Tyrer, PC; Akarca, AU; Janghra, N; Britten, CE; Havenith, CEG; ... Hartley, JA; + view all (2016) ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies. Molecular Cancer Therapeutics , 15 (11) pp. 2709-2721. 10.1158/1535-7163.MCT-16-0233. Green open access
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Forster, M; Mendes, R; Harrington, K; Guerrero-Urbano, T; Baines, H; Spanswick, V; Ensell, L; ... Beare, S; + view all (2016) A phase I study of olaparib in addition to cisplatin-based concurrent chemoradiotherapy for patients with high risk locally advanced squamous cell carcinoma of the head and neck (HNSCC). Presented at: 2016 ASCO Annual Meeting, Chicago, IL, USA. Green open access
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Forster, MD; Mendes, R; Harrington, KJ; Urbano, TG; Baines, H; Spanswick, VJ; Ensell, L; ... Beare, S; + view all (2016) ORCA-2: A phase I study of olaparib in addition to cisplatin-based concurrent chemoradiotherapy for patients with high risk locally advanced squamous cell carcinoma of the head and neck. Presented at: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Foulon, S; Brennan, B; Gaspar, N; Dirksen, U; Jeys, L; Cassoni, A; Claude, L; ... Le Deley, M-C; + view all (2016) Can postoperative radiotherapy be omitted in localised standard-risk Ewing sarcoma? An observational study of the Euro-E.W.I.N.G group. Eur J Cancer , 61 pp. 128-136. 10.1016/j.ejca.2016.03.075.

Foxall, E; Pipili, A; Jones, GE; Wells, CM; (2016) Significance of kinase activity in the dynamic invadosome. European Journal of Cell Biology , 95 (11) pp. 483-492. 10.1016/j.ejcb.2016.07.002. Green open access
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Francis, A; Stein, RC; Marshall, A; Rea, DW; Cameron, DA; Macpherson, IR; Earl, HM; ... Dunn, JA; + view all (2016) OPTIMA (Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis): A prospective trial to validate the predictive utility and cost-effectiveness of gene expression test-directed chemotherapy decisions. Presented at: UNSPECIFIED.

Franklin, JM; Sharma, RA; Harris, AL; Gleeson, FV; (2016) Imaging oligometastatic cancer before local treatment. The Lancet Oncology , 17 (9) e406-e414. 10.1016/S1470-2045(16)30277-7. Green open access
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Gillessen, S; Omlin, A; Attard, G; de Bono, JS; Efstathiou, E; Fizazi, K; Halabi, S; ... Tombal, B; + view all (2016) Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. Annals of Oncology , 26 pp. 1589-1604. 10.1093/annonc/mdw180. Green open access
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Goh, G; Schmid, R; Guiver, K; Arpornwirat, W; Chitapanarux, I; Ganju, V; Im, SA; ... Swanton, C; + view all (2016) Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine. PLOS Med , 13 (12) , Article e1002136. 10.1371/journal.pmed.1002136. Green open access
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H

Hall, AR; Burke, N; Dongworth, RK; Kalkhoran, SB; Dyson, A; Vicencio, JM; Dorn Ii, GW; ... Hausenloy, DJ; + view all (2016) Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction. Cell Death and Disease , 7 , Article e2238. 10.1038/cddis.2016.139. Green open access
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Harrington, K; Forster, M; Dillon, M; Grove, L; Adeleke, S; Chen, S; Diamond, J; ... Greenberg, J; + view all (2016) Patritumab or Placebo Plus Cetuximab and Platinum-Based Therapy in Squamous Cell Carcinoma of the Head and Neck (SCCHN): a Phase 2 Study. Presented at: ASCO 2016 Annual Meeting: Poster Session, Head and Neck Cancer, Chicago. Green open access
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Henson, KE; Reulen, RC; Winter, DL; Bright, CJ; Fidler, MM; Frobisher, C; Guha, J; ... Hawkins, MM; + view all (2016) Cardiac Mortality Among 200 000 Five-Year Survivors of Cancer Diagnosed at 15 to 39 Years of Age: The Teenage and Young Adult Cancer Survivor Study. Circulation , 134 (20) pp. 1519-1531. 10.1161/CIRCULATIONAHA.116.022514. Green open access
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Hiley, CT; Le Quesne, J; Santis, G; Sharpe, R; De Castro, DG; Middleton, G; Swanton, C; (2016) Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease. The Lancet , 388 (10048) pp. 1002-1011. 10.1016/S0140-6736(16)31340-X. Green open access
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Hofmanová, Z; Kreutzer, S; Hellenthal, G; Sell, C; Diekmann, Y; Díez-Del-Molino, D; van Dorp, L; ... Burger, J; + view all (2016) Early farmers from across Europe directly descended from Neolithic Aegeans. Proceedings of the National Academy of Sciences of the United States of America , 113 (25) pp. 6886-6891. 10.1073/pnas.1523951113. Green open access
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Hopper, C; Jerjes, W; Sultan, A; Forster, M; carnell, D; Simeon, C; Berg, K; ... Hamdoon, Z; + view all (2016) Disulfonated tetraphenyl chlorin (TPCS2a)–induced photochemical internalisation of bleomycin in patients with solid malignancies: A first-in-man phase I dose escalation clinical trial. The Lancet Oncology , 17 (9) pp. 1217-1229. 10.1016/S1470-2045(16)30224-8. Green open access
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Hughes, A; Landers, D; Arkenau, H-T; Shah, S; Stephens, R; Mahal, A; Simmons, M; ... Royle, J; + view all (2016) Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT. Advances in Therapy , 33 (6) pp. 1012-1024. 10.1007/s12325-016-0335-4. Green open access
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Hurt, C; Bridgewater, J; Falk, S; Cummins, S; Wasan, H; Crosby, T; Radhakrishna, G; ... Mukherjee, S; + view all (2016) Long-term outcome from the SCALOP trial: a multi-centre randomized phase II trial of gemcitabine or capecitabine-based chemoradiation (CRT) for locally advanced pancreatic cancer (LAPC). Presented at: 18th World Congress of the European-Society-for-Medical-Oncology (ESMO) on Gastrointestinal Cancer, Barcelona, SPAIN.

Hynds, RE; (2016) Characterisation of cultured airway basal cells to understand their role in human lung disease. Doctoral thesis , UCL (University College London). Green open access
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Hynds, RE; Butler, CR; Janes, SM; Giangreco, A; (2016) Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres. Methods in Molecular Biology pp. 1-11. 10.1007/7651_2016_5. (In press). Green open access
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James, ND; Sydes, MR; Clarke, NW; Mason, MD; Dearnaley, DP; Spears, MR; Ritchie, AW; ... STAMPEDE investigators, ; + view all (2016) Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial. Lancet , 387 (10024) pp. 1163-1177. 10.1016/S0140-6736(15)01037-5. Green open access
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Johnsson, M; Gering, E; Willis, P; Lopez, S; Van Dorp, L; Hellenthal, G; Henriksen, R; ... Wright, D; + view all (2016) Feralisation targets different genomic loci to domestication in the chicken. Nature Communications , 7 , Article 12950. 10.1038/ncomms12950. Green open access
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Johnston, EW; Pye, H; Bonet Carne, E; Panagiotaki, E; Patel, D; Galazi, M; Heavey, S; ... Punwani, S; + view all (2016) INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer. BMC Cancer , 16 (816) 10.1186/s12885-016-2856-2. Green open access
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Kanu, N; Cerone, MA; Goh, G; Zalmas, L-P; Bartkova, J; Dietzen, M; McGranahan, N; ... Swanton, C; + view all (2016) DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer. Genome Biology , 17 , Article 185. 10.1186/s13059-016-1042-9. Green open access
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Kim, R; Sharma, S; Meyer, T; Sarker, D; Macarulla, T; Sung, M; Choo, SP; ... Llovet, JM; + view all (2016) First-in-human study of BLU-554, a potent, highly-selective FGFR4 inhibitor designed for hepatocellular carcinoma (HCC) with FGFR4 pathway activation. Presented at: 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Munich, GERMANY.

Kinna, A; Tolner, B; Rota, EM; Titchener-Hooker, N; Nesbeth, D; Chester, K; (2016) IMAC capture of recombinant protein from unclarified mammalian cell feed streams. Biotechnology and Bioengineering , 113 (1) pp. 130-140. 10.1002/bit.25705. Green open access
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Koffas, A; Watkins, J; Mohmaduvesh, M; Thirlwell, C; Meyer, T; Toumpanakis, C; Caplin, M; (2016) Analysis of Oesophageal Neuroendocrine Tumor Outcomes. Presented at: 57th Annual Meeting and Residents Fellow Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA.

Konecny, G; Kristeleit, RS; (2016) PARP inhibitors for BRCA1/2-mutated and sporadic ovarian cancer: current practice and future directions. British Journal of Cancer , 115 pp. 1157-1173. 10.1038/bjc.2016.311. Green open access
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Kotwinski, PJ; Smith, G; Cooper, J; Sanders, J; Ma, L; Teis, A; Kotwinski, D; ... Breast cancer Early disease: Toxicity from Therapy with Epirubic, ; + view all (2016) Body Surface Area and Baseline Blood Pressure Predict Subclinical Anthracycline Cardiotoxicity in Women Treated for Early Breast Cancer. PLOS One , 11 (12) , Article e0165262. 10.1371/journal.pone.0165262. Green open access
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Kristeleit, RS; Miller, RE; Kohn, EC; (2016) Gynecologic Cancers: Emerging Novel Strategies for Targeting DNA Repair Deficiency. American Society of Clinical Oncology Educational Book , 2016 10.14694/EDBK_159086. Green open access
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Kristeleit, RS; Miller, RE; Sellers, LE; Brown, NF; Gougis, P; Boyd, A; Morris, G; ... Linch, M; + view all (2016) A first-in-human (FIH) phase I/II, dose escalation, pharmacokinetic (PK) study to assess the safety and tolerability of VAL-201 in patients with advanced prostate cancer (APC) and other advanced solid tumours. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Kristeleit, RS; Shapira-Frommer, R; Oaknin, A; Balmana, J; Ray-Coquard, IL; Domchek, S; Tinker, AV; ... Oza, A; + view all (2016) Clinical activity of the poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with high-grade ovarian carcinoma (HGOC) and a BRCA mutation (BRCAmut): Analysis of pooled data from Study 10 (parts 1, 2a, and 3) and ARIEL2 (parts 1 and 2). Presented at: 41st ESMO Congress (ESMO 2016), Copenhagen, Denmark.

Kularatne, B; Arora, R; Elshstein, G; Guppy, N; Kirkwood, A; Meyer, T; Kristeleit, RS; (2016) Immunohistochemistry (IHC) evaluation of a novel 4-protein prognostic and predictive biomarker panel in endometrial cancer (EC). In: Abstract Book of the 41st ESMO Congress (ESMO 2016), 7-11 October 2016, Copenhagen, Denmar. Oxford University Press (OUP): Policy A1 Green open access
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Laethem, J-LV; Riess, H; Jassem, J; Haas, M; Martens, UM; Weekes, C; Peeters, M; ... Childs, BH; + view all (2016) Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer. Targeted Oncology , 12 (1) pp. 97-109. 10.1007/s11523-016-0469-y. Green open access
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Lampada, A; (2016) Targeting autophagy in colorectal cancer. Doctoral thesis , UCL (University College London). Green open access
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Laskaratos, F-M; Walker, M; Naik, K; Maragkoudakis, E; Oikonomopoulos, N; Grant, L; Meyer, T; ... Toumpanakis, C; + view all (2016) Predictive factors of antiproliferative activity of octreotide LAR as first-line therapy for advanced neuroendocrine tumours. British Journal of Cancer , 115 (11) pp. 1321-1327. 10.1038/bjc.2016.349. Green open access
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Laurent-Puig, P; Balogoun, R; Cayre, A; Le Malicot, K; Tabernero, J; Mini, E; Folprecht, G; ... Taieb, J; + view all (2016) ERBB2 alterations a new prognostic biomarker in stage III colon cancer from a FOLFOX based adjuvant trial (PETACC8). Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Lawson, C; Vicencio, JM; Yellon, DM; Davidson, SM; (2016) Microvesicles and exosomes: new players in metabolic and cardiovascular disease. Journal of Endocrinology , 228 (2) R57-R71. 10.1530/JOE-15-0201. Green open access
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Lechner, M; Fenton, TR; (2016) Chapter One - The Genomics, Epigenomics, and Transcriptomics of HPV-Associated Oropharyngeal Cancer - Understanding the Basis of a Rapidly Evolving Disease. Advances in Genetics , 93 pp. 1-56. 10.1016/bs.adgen.2015.12.001.

Ledermann, JA; Drew, Y; Kristeleit, RS; (2016) Homologous recombination deficiency and ovarian cancer. European Journal of Cancer , 60 pp. 49-58. 10.1016/j.ejca.2016.03.005. Green open access
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Lee, AJX; Benamore, R; Hofer, M; Chitnis, M; (2016) Leptomeningeal carcinomatosis in non-small-cell lung cancer: initial response to erlotinib followed by relapse despite continuing radiological resolution of disease. Oxford Medical Case Reports , 2016 (9) , Article omw069. 10.1093/omcr/omw069. Green open access
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Lee, SM; Falzon, M; Blackhall, F; Spicer, J; Nicolson, M; Chaudhuri, A; Middleton, G; ... Hackshaw, A; + view all (2016) Randomized Prospective Biomarker Trial of ERCC1 for Comparing Platinum and Nonplatinum Therapy in Advanced Non-Small-Cell Lung Cancer: ERCC1 Trial (ET). Journal of Clinical Oncology , 35 (4) pp. 402-411. 10.1200/JCO.2016.68.1841. Green open access
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Lemech, CR; Ensell, L; Paterson, JC; Eminowicz, G; Lowe, H; Arora, R; Arkenau, H-T; ... Kristeleit, RS; + view all (2016) Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer. Oncology , 91 (1) pp. 48-54. 10.1159/000445999. Green open access
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Lopez-Guadamillas, E; Fernandez-Marcos, PJ; Pantoja, C; Muñoz-Martin, M; Martínez, D; Gómez-López, G; Campos-Olivas, R; ... Serrano, M; + view all (2016) p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPARα. Sci Rep , 6 , Article 34542. 10.1038/srep34542. Green open access
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Lopez-Guadamillas, E; Muñoz-Martin, M; Martinez, S; Pastor, J; Fernandez-Marcos, PJ; Serrano, M; (2016) PI3Kα inhibition reduces obesity in mice. Aging , 8 (11) pp. 2747-2753. 10.18632/aging.101075. Green open access
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Lorente, D; Omlin, A; Zafeiriou, Z; Nava-Rodrigues, D; Pérez-López, R; Pezaro, C; Mehra, N; ... de Bono, J; + view all (2016) Castration-Resistant Prostate Cancer Tissue Acquisition From Bone Metastases for Molecular Analyses. Clinical Genitourinary Cancer , 14 (6) pp. 485-493. 10.1016/j.clgc.2016.04.016. Green open access
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M

Mandair, D; Vesely, C; Ensell, L; Lowe, H; Spanswick, V; Hartley, JA; Caplin, ME; (2016) A comparison of CellCollector with CellSearch in patients with neuroendocrine tumours. Endocrine-Related Cancer , 23 (10) L29-L32. 10.1530/ERC-16-0201. Green open access
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Marina, NM; Smeland, S; Bielack, SS; Bernstein, M; Jovic, G; Krailo, MD; Hook, JM; ... Whelan, JS; + view all (2016) Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial. The Lancet Oncology , 17 (10) pp. 1396-1408. 10.1016/S1470-2045(16)30214-5. Green open access
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Maughan, E; Lesage, F; Butler, CR; Hynds, RE; Hewitt, R; Janes, SM; Deprest, JA; (2016) Airway tissue engineering for congenital laryngotracheal disease. Seminars in Pediatric Surgery , 25 (3) pp. 186-190. 10.1053/j.sempedsurg.2016.02.012. Green open access
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McLean, BA; Zhabyeyev, P; Chen, X; Haromy, A; Vanhaesebroeck, B; Michelakis, ED; Oudit, GY; (2016) PI3K alpha Deletion in Cardiomyocytes Causes Maintained Mitochondrial Membrane Potential and Blocks Necrotic Cell Death in Ischemia/Reperfusion Injury. Presented at: Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, New Orleans, LA.

McLean, BA; Zhabyeyev, P; Chen, X; Haromy, A; Vanhaesebroeck, B; Michelakis, ED; Oudit, GY; (2016) PI3K alpha Deletion in Cardiomyocytes Causes Maintained Mitochondrial Membrane Potential and Blocks Necrotic Cell Death in Ischemia/Reperfusion Injury. Presented at: Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, New Orleans, LA.

Melero, I; Sangro, B; Yau, T; Hsu, C; Kudo, M; Crocenzi, TS; Kim, T-Y; ... El-Khoueiry, AB; + view all (2016) Nivolumab (Nivo) in Patients (Pts) With Advanced Hepatocellular Carcinoma (HCC): the CheckMate 040 Study. Presented at: 67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston, MA.

Michael, A; Lord, R; Hall, G; Hanna, L; Anand, A; Walther, A; Nicum, S; ... Ledermann, JA; + view all (2016) TRIOC: A randomised parallel group double-blind phase II study to assess the activity of MVA-5T4 vaccine versus placebo in patients with relapsed asymptomatic epithelial ovarian, fallopian tube, or primary peritoneal cancer. Presented at: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Miller, R; Childs, A; Gillmore, R; Mayer, A; Thirlwell, C; Meyer, T; (2016) The Role of Interval CT Scanning in Patients Undergoing Palliative Chemotherapy for Metastatic Neuroendocrine Tumours (NETs). Presented at: 13th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, SPAIN.

Miller, RE; Brown, NE; Speirs, A; Shaw, HM; Adeleke, S; Gougis, P; Bennett, P; ... Kristeleit, RS; + view all (2016) The use of next generation sequencing (NGS) to guide patient selection for phase 1 clinical trials. Annals of Oncology , 27 (Suppl 6) pp. 114-135. 10.1093/annonc/mdw368.44. Green open access
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Milojkovic Kerklaan, B; Slater, S; Flynn, M; Greystoke, A; Witteveen, PO; Megui-Roelvink, M; de Vos, F; ... Schellens, JHM; + view all (2016) A phase I, dose escalation, pharmacodynamic, pharmacokinetic, and food-effect study of α2 integrin inhibitor E7820 in patients with advanced solid tumors. Invest New Drugs , 34 (3) pp. 329-337. 10.1007/s10637-016-0344-9.

N

Nannini, F; Parekh, F; Jakubowska, A; Akarca, A; Marafioti, T; Chester, K; Onuoha, S; ... Pule, M; + view all (2016) Development of novel anti-CD160 CARs. Presented at: Conference on Changing the Face of Modern Medicine - Stem Cells and Gene Therapy, Florence, ITALY.

Neoptolemos, JP; Palmer, D; Ghaneh, P; Valle, J; Cunningham, D; Wadsley, J; Meyer, T; ... Buechler, MW; + view all (2016) ESPAC-4: A Multicenter, International, Randomized Controlled Phase III Trial of Adjuvant Combination Chemotherapy of Gemcitabine (GEM) and Capecitabine (CAP), Versus Monotherapy Gemcitabine in Patients With Resected Pancreatic Ductal Adenocarcinoma. Presented at: UNSPECIFIED.

O

O'Connor, JP; Aboagye, EO; Adams, JE; Aerts, HJ; Barrington, SF; Beer, AJ; Boellaard, R; ... Waterton, JC; + view all (2016) Imaging biomarker roadmap for cancer studies. Nat Rev Clin Oncol 10.1038/nrclinonc.2016.162. (In press). Green open access
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Okkenhaug, K; Graupera, M; Vanhaesebroeck, B; (2016) Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy. Cancer Discovery , 6 (10) pp. 1090-1105. 10.1158/2159-8290.CD-16-0716. Green open access
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Paz, KG; Flynn, R; Du, J; Dong, S; Okkenhaug, K; Stark, A-K; Vanhaesebroeck, B; ... Blazar, BR; + view all (2016) Targeting PI3K signaling to ameliorate chronic graft versus host disease. Presented at: Annual Meeting of the American-Association-of-Immunologists (AAI), Seattle, WA.

Perna, C; Eminowicz, G; Asghar, U; Imseeh, G; Kirkwood, A; Mitra, A; Arora, R; ... McCormack, M; + view all (2016) Uterine carcinosarcoma: a retrospective clinical cohort analysis. Presented at: ESMO 2016: 41st ESMO Congress, Copenhagen, Denmark. Green open access
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Pugh, SA; Bowers, M; Ball, A; Falk, S; Finch-Jones, M; Valle, JW; O'Reilly, DA; ... Primrose, JN; + view all (2016) Patterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study. British Journal of Cancer , 115 (4) pp. 420-424. 10.1038/bjc.2016.208. Green open access
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Pye, H; Butt, MA; Reinert, HW; Maruani, A; Nunes, JP; Marklew, JS; Qurashi, M; ... Lovat, LB; + view all (2016) A HER2 selective theranostic agent for surgical resection guidance and photodynamic therapy. Photochemical & Photobiological Sciences , 15 (10) pp. 1227-1238. 10.1039/c6pp00139d. Green open access
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Richardson, SE; (2016) Modeling TEL-AML1 childhood acute lymphoblastic leukaemia using human pluripotent stem cells. Doctoral thesis , UCL (University College London).

Riquelme, JA; Westermeier, F; Hall, AR; Vicencio, JM; Pedrozo, Z; Ibacache, M; Fuenzalida, B; ... Lavandero, S; + view all (2016) Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism. Pharmacological Research , 103 pp. 318-327. 10.1016/j.phrs.2015.11.004. Green open access
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Rooshenas, L; Elliott, D; Wade, J; Jepson, M; Paramasivan, S; Strong, S; Wilson, C; ... POUT study group, ; + view all (2016) Conveying Equipoise during Recruitment for Clinical Trials: Qualitative Synthesis of Clinicians' Practices across Six Randomised Controlled Trials. PLoS Med , 13 (10) , Article e1002147. 10.1371/journal.pmed.1002147. Green open access
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Rosenthal, R; McGranahan, N; Herrero, J; Taylor, BS; Swanton, C; (2016) deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution. Genome Biol , 17 (1) p. 31. 10.1186/s13059-016-0893-4. Green open access
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Rothermundt, C; Seddon, BM; Dileo, P; Strauss, SJ; Coleman, J; Briggs, TW; Haile, SR; (2016) Follow-up practices for high-grade extremity Osteosarcoma. BMC Cancer , 16 , Article 301. 10.1186/s12885-016-2333-y. Green open access
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Rowley, MI; Coolen, ACC; Vojnovic, B; Barber, PR; (2016) Correction: Robust Bayesian fluorescence lifetime estimation, decay model selection and instrument response determination for low-intensity FLIM imaging. PLoS ONE , 11 (8) , Article e0162224. 10.1371/journal.pone.0162224. Green open access
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Rowley, MI; Coolen, ACC; Vojnovic, B; Barber, PR; (2016) Robust Bayesian Fluorescence Lifetime Estimation, Decay Model Selection and Instrument Response Determination for Low-Intensity FLIM Imaging. PLoS One , 11 (6) , Article e0158404. 10.1371/journal.pone.0158404. Green open access
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rown, N; Carter, T; Shaw, H; Ottaviani, D; Chester, K; Mulholland, P; (2016) DOES THE OCCURRENCE OF A RASH CORRELATE WITH RESPONSE IN GLIOBLASTOMA PATIENTS TREATED WITH IPILIMUMAB? Presented at: 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale, AZ.

S

Salvi, S; Casadio, V; Conteduca, V; Lolli, C; Gurioli, G; Martignano, F; Schepisi, G; ... De Giorgi, U; + view all (2016) Circulating AR copy number and outcome to enzalutamide in docetaxel-treated metastatic castration-resistant prostate cancer. Oncotarget , 7 (25) pp. 37839-37845. 10.18632/oncotarget.9341. Green open access
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Savas, P; Teo, ZL; Lefevre, C; Flensburg, C; Caramia, F; Alsop, K; Mansour, M; ... Loi, S; + view all (2016) The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE". PLoS Medicine , 13 (12) , Article e1002204. 10.1371/journal.pmed.1002204. Green open access
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Scelo, G; Hofmann, JN; Banks, RE; Bigot, P; Bhatt, RS; Cancel-Tassin, G; Chew, SK; ... Chanock, SJ; + view all (2016) International cancer seminars: a focus on kidney cancer. Annals of Oncology , 27 (8) pp. 1382-1385. 10.1093/annonc/mdw186. Green open access
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Schaefer, E; Braiteh, F; Forster, M; Talbot, D; Chandler, J; Richards, D; Andre, V; ... Nikolinakos, P; + view all (2016) Phase 1b/2 trial of taladegib (LY2940680), a Hh/Smo inhibitor, in combination with carboplatin and etoposide followed by taladegib maintenance in extensive-stage small-cell lung cancer. Presented at: 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Munich, GERMANY.

Scheipl, S; Barnard, M; Cottone, L; Jorgensen, M; Drewry, DH; Zuercher, WJ; Turlais, F; ... Flanagan, AM; + view all (2016) EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen. J Pathol , 239 (3) pp. 320-334. 10.1002/path.4729. Green open access
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Seifert, W; Posor, Y; Schu, P; Stenbeck, G; Mundlos, S; Klaassen, S; Nuernberg, P; ... Kuehnisch, J; + view all (2016) The progressive ankylosis protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface. Human Molecular Genetics , 25 (17) pp. 3836-3848. 10.1093/hmg/ddw230. Green open access
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Sharma, RA; Plummer, R; Stock, JK; Greenhalgh, TA; Ataman, O; Kelly, S; Clay, R; ... Wedge, SR; + view all (2016) Clinical development of new drug-radiotherapy combinations. NATURE REVIEWS CLINICAL ONCOLOGY , 13 (10) pp. 627-642. 10.1038/nrclinonc.2016.79. Green open access
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Shiao, J; Winter, H; Sharma, RA; (2016) Landmark study raises the bar for interventional oncology. Future Oncology , 12 (15) pp. 1747-1749. 10.2217/fon-2016-0212. Green open access
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Siriwardana, PN; Barrett, JE; Luong, T; Watkins, J; Singh, S; Kim, P; Hochhauser, D; ... Davidson, BR; + view all (2016) THE INTERACTION BETWEEN THE HYPOXIA INDUCIBLE FACTOR-1A (HIF-1A) AND ERBB SIGNALLING PATHWAYS IN COLORECTAL LIVER METASTASES (CRLM). Presented at: UNSPECIFIED.

Siriwardana, PN; Hochhauser, D; Davidson, BR; (2016) The proof-of-concept project to develop an ex-vivo perfusion model, to study the real-time molecular changes and therapeutic methods of colorectal liver metastases (CRLM). Presented at: Annual Meeting of the Society-of-Academic-and-Research-Surgery (SARS), Royal Coll Surg England, London, ENGLAND.

Siriwardana, PN; Luong, T; Watkins, J; Hochhauser, D; Harris, A; Davidson, BR; Ong, W; (2016) TEN YEAR FOLLOW UP CASE CONTROL STUDY OF THE EFFECT OF PORTAL VEIN EMBOLISATION (PVE) ON THE SURVIVAL OF PATIENTS WITH COLORECTAL LIVER METASTASES (CRLM) AND THE INFLUENCE OF HYPOXIA FACTORS ON TUMOUR GROWTH. Presented at: UNSPECIFIED.

Siriwardana, PN; Luong, TV; Watkins, J; Turley, H; Gatter, K; Harris, A; Hochhauser, D; (2016) Ten year follow up case control study of the effect of portal vein embolization (PVE) on the survival of patients with colorectal liver metastases (CRLM) and the influence of hypoxia factors on tumour growth. Presented at: Annual Meeting of the Society-of-Academic-and-Research-Surgery (SARS), Royal Coll Surg England, London, ENGLAND.

Soria, JC; Gan, HK; Blagden, SP; Plummer, R; Arkenau, HT; Ranson, M; Evans, TRJ; ... Millward, M; + view all (2016) A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors. Annals of Oncology , 27 (12) pp. 2268-2274. 10.1093/annonc/mdw427. Green open access
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Stein, RC; Dunn, JA; Bartlett, JMS; Campbell, AF; Marshall, A; Hall, P; Rooshenas, L; ... Makris, A; + view all (2016) OPTIMA: a randomised feasibility study of personalised care in the treatment of women with early breast cancer. (Health Technology Assessment 20(10) , pp. pp. 1-202 ). National Institute of Health Research: UK. Green open access
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Succony, L; Gowers, KHC; Hynds, RE; Thakrar, R; Giangreco, A; Davies, D; Janes, S; (2016) THE ROLE OF LRIG1-DEPENDENT EGFR SIGNALLING IN AIRWAY HOMOEOSTASIS AND SQUAMOUS CELL LUNG CANCER DEVELOPMENT. Presented at: UNSPECIFIED.

Swanton, C; Govindan, R; (2016) Clinical Implications of Genomic Discoveries in Lung Cancer. New England Journal of Medicine , 374 (19) pp. 1864-1873. 10.1056/NEJMra1504688. Green open access
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Szikriszt, B; Poti, A; Pipek, O; Krzystanek, M; Kanu, N; Molnar, J; Ribli, D; ... Szuts, D; + view all (2016) A comprehensive survey of the mutagenic impact of common cancer cytotoxics. Genome Biology , 17 , Article 99. 10.1186/s13059-016-0963-7. Green open access
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Taieb, J; Balogoun, R; Le Malicot, K; Tabernero, J; Mini, E; Folprecht, G; Van Laethem, JL; ... PETACC8 investigators, .; + view all (2016) Adjuvant FOLFOX +/- cetuximab in full RAS and BRAF wildtype stage III colon cancer patients. Annals of Oncology 10.1093/annonc/mdw687. (In press). Green open access
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Taieb, J; Le Malicot, K; Balogoum, R; Tabernero, J; Mini, E; Folprecht, G; van Laethem, J-L; ... Laurent-Puig, P; + view all (2016) Adjuvant FOLFOX plus cetuximab vs FOLFOX in full RAS and BRAF wild type stage III colon cancer patients: Results from the PETACC8 trial. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Tape, CJ; Ling, S; Dimitriadi, M; McMahon, KM; Worboys, JD; Leong, HS; Norrie, IC; ... Jorgensen, C; + view all (2016) Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation. Cell , 165 (4) pp. 910-920. 10.1016/j.cell.2016.03.029. Green open access
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Taylor, RM; Fern, LA; Aslam, N; Whelan, JS; (2016) Direct access to potential research participants for a cohort study using a confidentiality waiver included in UK National Health Service legal statutes. BMJ Open , 6 (8) , Article e011847. 10.1136/bmjopen-2016-011847. Green open access
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Terrisse, AD; Laurent, PA; Garcia, C; Gratacap, MP; Vanhaesebroeck, B; Sié, P; Payrastre, B; (2016) The class I phosphoinositide 3-kinases α and β control antiphospholipid antibodies-induced platelet activation. Thrombosis and Haemostasis 10.1160/TH15-08-0661. Green open access
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Tosatto, A; Sommaggio, R; Kummerow, C; Bentham, RB; Blacker, TS; Berecz, T; Duchen, MR; ... Mammucari, C; + view all (2016) The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α. EMBO Molecular Medicine , 8 (5) pp. 569-585. 10.15252/emmm.201606255. Green open access
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Tree, AC; Harding, V; Bhangu, A; Krishnasamy, V; Morton, D; Stebbing, J; Wood, BJ; (2016) The need for multidisciplinarity in specialist training to optimize future patient care. Nature Reviews Clinical Oncology 10.1038/nrclinonc.2016.185. (In press). Green open access
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Tudzarova, S; Mulholland, P; Dey, A; Stoeber, K; Okorokov, AL; Williams, GH; (2016) p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress. Cell Cycle , 15 (21) pp. 2958-2972. 10.1080/15384101.2016.1231281. Green open access
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Turati, VA; Guerra-Assuncao, JA; Ambrose, JC; Brown, J; Hubank, M; Hobbs, A; Lynch, M; ... Enver, T; + view all (2016) Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy. Presented at: 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA.

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Vanhaesebroeck, B; Whitehead, MA; Pineiro, R; (2016) Molecules in medicine mini-review: isoforms of PI3K in biology and disease. Journal of Molecular Medicine , 94 (1) pp. 5-11. 10.1007/s00109-015-1352-5. Green open access
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Vassiliou, LV; Lalabekyan, B; Jay, A; Liew, C; Whelan, J; Newman, L; Kalavrezos, N; (2016) Head and neck sarcomas: A single institute series. Oral Oncology , 65 pp. 16-22. 10.1016/j.oraloncology.2016.12.005. Green open access
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Vena, F; (2016) MEK inhibition in pancreas cancer. Doctoral thesis , UCL (University College London). Green open access
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Vindrola-Padros, C; Taylor, RM; Lea, S; Hooker, L; Pearce, S; Whelan, J; Gibson, F; (2016) Mapping Adolescent Cancer Services: How Do Young People, Their Families, and Staff Describe Specialized Cancer Care in England? Cancer Nursing , 39 (5) pp. 358-366. 10.1097/NCC.0000000000000315. Green open access
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Weitsman, G; Barber, PR; Nguyen, LK; Lawler, K; Patel, G; Woodman, N; Kelleher, MT; ... Ng, T; + view all (2016) HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status. Oncotarget , 7 (32) pp. 51012-51026. 10.18632/oncotarget.9963. Green open access
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Wulaningsih, W; Holmberg, L; Abeler-Doner, L; Ng, T; Rohrmann, S; Van Hemelrijck, M; (2016) Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women. PLoS ONE , 11 (6) , Article e0157482. 10.1371/journal.pone.0157482. Green open access
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Wulaningsih, W; Holmberg, L; Garmo, H; Karagiannis, SN; Ahlstedt, S; Malmstrom, H; Lambe, M; ... Van Hemelrijck, M; + view all (2016) Investigating the association between allergen-specific immunoglobulin E, cancer risk and survival. Oncoimmunology , 5 (6) , Article e1154250. 10.1080/2162402X.2016.1154250. Green open access
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Zamborszky, J; Szikriszt, B; Gervai, JZ; Pipek, O; Poti, A; Krzystanek, M; Ribli, D; ... Szuets, D; + view all (2016) Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions. Oncogene , 36 (6) pp. 746-755. 10.1038/onc.2016.243. Green open access
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Zammarchi, F; Chivers, S; Williams, DG; Adams, L; Mellinas-Gomez, M; Tyrer, P; Corbett, S; ... Van Berkel, PH; + view all (2016) ADCT-502, a novel pyrrolobenzodiazepine (PBD)-based antibody-drug conjugate (ADC) targeting low HER2-expressing solid cancers. Presented at: 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Munich, GERMANY.

Zhang, R; Fruhwirth, GO; Coban, O; Barrett, JE; Burgoyne, T; Lee, SH; Simonson, PD; ... Selvin, PR; + view all (2016) Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-Resolution Microscopy. ACS Nano , 11 (1) pp. 249-257. 10.1021/acsnano.6b05356. Green open access
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Zubairi, I; Dean, E; Molife, LR; Lopez, J; Ranson, M; El-Khouly, F; Savulsky, C; ... Evans, TRJ; + view all (2016) Phase 1 multicenter, open-label study to establish the maximum tolerated dose (MTD) of two administration schedules of E7389 (eribulin) liposomal formulation in patients (pts) with solid tumors. Presented at: 2016 Jahrestagung der DGHO, OeGHO, SGMO und SGH, Leipzig, Germany.

This list was generated on Sun Jun 16 05:06:07 2019 BST.