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Number of items: 148.


Andrady, C; Sharma, SK; Chester, KA; (2011) Antibody-enzyme fusion proteins for cancer therapy. IMMUNOTHERAPY-UK , 3 (2) 193 - 211. 10.2217/IMT.10.90.

Ang, JE; Olmos, D; Garcia, VM; Brunetto, A; Papadatos-Pastos, D; Arkenau, H; Blanco, M; ... Kaye, SB; + view all (2011) Utility of novel dynamic clinical indices in patients (pts) enrolled in a phase I (Ph I) oncology trial as markers of prognosis and treatment benefit. In: AMER SOC CLINICAL ONCOLOGY

Ang, JE; Olmos, D; Moreno-Garcia, V; Brunetto, A; Papadatos-Pastos, D; Arkenau, HT; Blanco, M; ... Kaye, SB; + view all (2011) Utility of novel dynamic clinical indices in patients (pts) enrolled in a phase I (Ph I) oncology trial as markers of prognosis and treatment benefit. Journal of Clinical Oncology , 29 (Suppl 1)

Arkenau, H-K; (2011) Capecitabine combined with oxaliplatin (CAPOX) in clinical practice: how significant is peripheral neuropathy? ANNALS OF ONCOLOGY , 22 (1) 239-U282. 10.1093/annonc/mdq676.

Arkenau, H-T; Kefford, R; Long, GV; (2011) Targeting BRAF for patients with melanoma. BRITISH JOURNAL OF CANCER , 104 (3) pp. 392-398. 10.1038/sj.bjc.6606030.

Arkenau, H-T; Nordman, I; Dobbins, T; Ward, R; (2011) Reporting Time-to-Event Endpoints and Response Rates in 4 Decades of Randomized Controlled Trials in Advanced Colorectal Cancer. CANCER , 117 (4) pp. 832-840. 10.1002/cncr.25636.


Babu, B; Lee, M; Lee, L; Strobel, R; Brockway, O; Nickols, A; Sjoholm, R; ... Lee, M; + view all (2011) Acetyl analogs of combretastatin A-4: Synthesis and biological studies. BIOORGAN MED CHEM , 19 (7) 2359 - 2367. 10.1016/j.bmc.2011.02.018.

Babu, B; Liu, Y; Plaunt, A; Riddering, C; Ogilvie, R; Westrate, L; Davis, R; ... Lee, M; + view all (2011) Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI. BIOCHEM BIOPH RES CO , 404 (3) 848 - 852. 10.1016/j.bbrc.2010.12.073.

Babu, B; Ramos, J; Liu, Y; Chavda, S; Tzou, S; Brockway, O; Sjoholm, R; ... Lee, M; + view all (2011) Design, synthesis, and DNA binding selectivity and affinity studies of the tetraamide PhIPI and its diamino analog PhIP*I. In: (Proceedings) 242nd National Meeting of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Baird, RD; Venugopal, B; Kristeleit, RS; Charlton, J; Blanco-Codesido, M; Saunders, E; Shah, KJ; ... Evans, TRJ; + view all (2011) A first-in-human phase I study of JNJ-26481585, a novel oral histone deacetylase inhibitor (HDACi), in patients with advanced cancer with evidence of target modulation and antitumor activity. JOURNAL OF CLINICAL ONCOLOGY , 29 (15) 10.1200/jco.2011.29.15_suppl.3024.

Baker, M; Robinson, SD; Lechertier, T; Barber, PR; Tavora, B; D'Amico, G; Jones, DT; ... Hodivala-Dilke, K; + view all (2011) Use of the mouse aortic ring assay to study angiogenesis. Nat Protoc , 7 (1) pp. 89-104. 10.1038/nprot.2011.435.

Baraniskin, A; Munding, J; Schulmann, K; Meier, D; Porschen, R; Arkenau, H-T; Graeven, U; ... Reinacher-Schick, A; + view all (2011) Prognostic Value of Reduced SMAD4 Expression in Patients With Metastatic Colorectal Cancer Under Oxaliplatin-Containing Chemotherapy: A Translational Study of the AIO Colorectal Study Group. CLINICAL COLORECTAL CANCER , 10 (1) pp. 24-29. 10.3816/CCC.2011.n.003.

Barton, S; Swanton, C; (2011) Recent Developments in Treatment Stratification for Metastatic Breast Cancer. DRUGS , 71 (16) pp. 2099-2113. 10.2165/11594480-000000000-00000.

Beltran, L; Chaussade, C; Vanhaesebroeck, B; Cutillas, PR; (2011) Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 108 (39) pp. 16217-16222. 10.1073/pnas.1107692108.

Birkbak, NJ; Eklund, AC; Li, Q; McClelland, SE; Endesfelder, D; Tan, P; Tan, IB; ... Swanton, C; + view all (2011) Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer. CANCER RESEARCH , 71 (10) pp. 3447-3452. 10.1158/0008-5472.CAN-10-3667.

Bravo, R; Vicencio, JM; Parra, V; Troncoso, R; Munoz, JP; Bui, M; Quiroga, C; ... Lavandero, S; + view all (2011) Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress. J CELL SCI , 124 (13) 2143 - 2152. 10.1242/jcs.080762.

Bravo, R; Vicencio, JM; Parra, V; Troncoso, R; Munoz, JP; Bui, M; Quiroga, C; ... Lavandero, S; + view all (2011) Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress (vol 124, pg 2143, 2011). J CELL SCI , 124 (14) 2511 - 2511. 10.1242/jcs.095455.

Bridgewater, JA; Stubbs, C; Primrose, JN; National Cancer Research Institute (UK) Upper Gastrointestinal S, ; (2011) BILCAP: A randomized clinical trial evaluating adjuvant chemotherapy with capecitabine compared to expectant treatment alone following curative surgery for biliary tract cancer. J Clin Oncol , 29 (15_suppl) 4125-.

Brough, R; Frankum, JR; Sims, D; Mackay, A; Mendes-Pereira, AM; Bajrami, I; Costa-Cabral, S; ... Ashworth, A; + view all (2011) Functional Viability Profiles of Breast Cancer. CANCER DISCOVERY , 1 (3) pp. 260-273. 10.1158/2159-8290.CD-11-0107.

Brown, NF; Marks, DJB; Smith, PJ; Bloom, SL; (2011) Splenomegaly. Br J Hosp Med (Lond) , 72 (11) M166-M169.

Brucoli, F; Hawkins, RM; James, CH; Wells, G; Jenkins, TC; Ellis, T; Hartley, JA; ... Thurston, DE; + view all (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. BIOORG MED CHEM LETT , 21 (12) 3780 - 3783. 10.1016/j.bmcl.2011.04.054.

Brunetto, A; Olmos, D; Arkenau, H-T; Tan, D; Yap, T; de Bono, J; Barriuso, J; (2011) Perceptions and referral trends into phase I oncology trials: results of a clinical survey. J Oncol , 2011 861401-. 10.1155/2011/861401.


Calvert, AH; (2011) Synthetic lethality in cancer treatment: Current status of PARP inhibitors. In: ANNALS OF ONCOLOGY. (pp. 13 - 13). OXFORD UNIV PRESS

Calvert, AH; Jackson, JC; Hutton, C; Swart, AM; Qian, W; Kwakye, C; Fossati, R; ... Lunec, J; + view all (2011) Evaluation of p53 mutation as a predictive biomarker for outcome to chemotherapy in ovarian cancer. J Clin Oncol , 29 (15_suppl) 10522-.

Calvert, H; Azzariti, A; (2011) The clinical development of inhibitors of poly(ADP-ribose) polymerase. ANNALS OF ONCOLOGY , 22 i53 - i59. 10.1093/annonc/mdq667.

Carlin, LM; Evans, R; Milewicz, H; Fernandes, L; Matthews, DR; Perani, M; Levitt, J; ... Ng, T; + view all (2011) A Targeted siRNA Screen Identifies Regulators of Cdc42 Activity at the Natural Killer Cell Immunological Synapse. SCIENCE SIGNALING , 4 (201) 10.1126/scisignal.2001729.

Cerone, MA; Burgess, DJ; Naceur-Lombardelli, C; Lord, CJ; Ashworth, A; (2011) High-throughput RNAi screening reveals novel regulators of telomerase. Cancer Res , 71 (9) pp. 3328-3340. 10.1158/0008-5472.CAN-10-2734.

Chavda, S; Liu, Y; Babu, B; Davis, R; Sielaff, A; Ruprich, J; Westrate, L; ... Lee, M; + view all (2011) Hx, a novel fluorescent, minor groove and sequence specific recognition element: Design, synthesis, and DNA binding properties of p-anisylbenzimidazole imidazole/pyrrole-containing polyamides. In: (Proceedings) 242nd National Meeting of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Chavda, S; Liu, Y; Babu, B; Davis, R; Sielaff, A; Ruprich, J; Westrate, L; ... Lee, M; + view all (2011) Hx, a Novel Fluorescent, Minor Groove and Sequence Specific Recognition Element: Design, Synthesis, and DNA Binding Properties of p-Anisylbenzimidazole-imidazole/pyrrole-Containing Polyamides. BIOCHEMISTRY-US , 50 (15) 3127 - 3136. 10.1021/bi102028a.

Chew, SK; Rad, R; Futreal, PA; Bradley, A; Liu, P; (2011) Genetic screens using the piggyBac transposon. Methods , 53 (4) pp. 366-371. 10.1016/j.ymeth.2010.12.022.

Coward, J; Kulbe, H; Chakravarty, P; Leader, D; Vassileva, V; Leinster, DA; Thompson, R; ... Balkwill, FR; + view all (2011) Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer. CLINICAL CANCER RESEARCH , 17 (18) pp. 6083-6096. 10.1158/1078-0432.CCR-11-0945.

Cox, ST; Stephens, HAF; Fernando, R; Karasu, A; Harber, M; Howie, AJ; Powis, S; ... Little, A-M; + view all (2011) Major histocompatibility complex class I-related chain A allele mismatching, antibodies, and rejection in renal transplantation. Hum Immunol , 72 (10) pp. 827-834. 10.1016/j.humimm.2011.05.004.


De Bono, JS; Logothetis, CJ; Molina, A; Fizazi, K; North, S; Chu, L; Chi, KN; ... Scher, HI; + view all (2011) Abiraterone and Increased Survival in Metastatic Prostate Cancer. NEW ENGLAND JOURNAL OF MEDICINE , 364 (21) pp. 1995-2005. 10.1056/NEJMoa1014618.

Dedes, KJ; Wetterskog, D; Ashworth, A; Kaye, SB; Reis-Filho, JS; (2011) Emerging therapeutic targets in endometrial cancer. NATURE REVIEWS CLINICAL ONCOLOGY , 8 (5) pp. 261-271. 10.1038/nrclinonc.2010.216.

Dedes, KJ; Wilkerson, PM; Wetterskog, D; Weigelt, B; Ashworth, A; Reis-Filho, JS; (2011) Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations. CELL CYCLE , 10 (8) pp. 1192-1199. 10.4161/cc.10.8.15273.


El-Khouly, F; Khan, MS; Toumpanakis, C; Meyer, T; Caplin, M; (2011) Challenges in the Management of VIPoma Patients. In: (Proceedings) 8th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocine Tumor Disease. (pp. pp. 3-4). KARGER

Endesfelder, D; McGranahan, N; Birkbak, NJ; Szallasi, Z; Kschischo, M; Graham, TA; Swanton, C; (2011) A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables. ONCOTARGET , 2 (7) pp. 529-537.

Ertemi, H; Mumtaz, FH; Howie, AJ; Mikhailidis, DP; Thompson, CS; (2011) Effect of Angiotensin II and its Receptor Antagonists on Human Corpus Cavernous Contractility and Oxidative Stress: Modulation of Nitric Oxide Mediated Relaxation. J UROLOGY , 185 (6) 2414 - 2420. 10.1016/j.juro.2011.02.2645.

Esfandiari, A; Shoaib, M; Hogarth, L; Panlilio, L; (2011) ESTABLISHING PAVLOVIAN TO INSTRUMENTAL TRANSFER (PIT) WITH INTRAVENOUS NICOTINE AND SUCROSE IN RATS. In: (Proceedings) Summer Meeting of the British-Association-for-Psychopharmacology. (pp. A44-A44). SAGE PUBLICATIONS LTD


Faelber, K; Posor, Y; Gao, S; Held, M; Roske, Y; Schulze, D; Haucke, V; ... Daumke, O; + view all (2011) Crystal structure of nucleotide-free dynamin. NATURE , 477 (7366) 556-U318. 10.1038/nature10369.

Feng, H; Hu, B; Liu, K-W; Li, Y; Lu, X; Cheng, T; Yiin, J-J; ... Cheng, S-Y; + view all (2011) Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans. J Clin Invest , 121 (12) pp. 4670-4684. 10.1172/JCI58559.

Fenton, TR; Gout, IT; (2011) Functions and regulation of the 70 kDa ribosomal S6 kinases. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY , 43 (1) pp. 47-59. 10.1016/j.biocel.2010.09.018.

Fern, LA; Campbell, C; Eden, TO; Grant, R; Lewis, I; Macleod, U; Weller, D; (2011) How frequently do young people with potential cancer symptoms present in primary care? Br J Gen Pract , 61 (586) e223-e230. 10.3399/bjgp11X572418.

Fisher, R; Larkin, J; Swanton, C; (2011) Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity. EPMA J , 3 (1) 1-. 10.1007/s13167-011-0137-3.

Forster, MD; Dedes, K; Sandhu, S; Frentzas, S; Kristeleit, R; Ashworth, A; Poole, C; ... Molife, LR; + view all (2011) Treatment with the PARP inhibitor olaparib in a patient with PTEN-deficient endometrial cancer. Nature Reviews Clinical Oncology , 8 (5) pp. 302-306.

Forster, MD; Dedes, KJ; Sandhu, S; Frentzas, S; Kristeleit, R; Ashworth, A; Poole, CJ; ... Molife, LR; + view all (2011) Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer. NATURE REVIEWS CLINICAL ONCOLOGY , 8 (5) pp. 302-306. 10.1038/nrclinonc.2011.42.

Fruhwirth, GO; Fernandes, LP; Weitsman, G; Patel, G; Kelleher, M; Lawler, K; Brock, A; ... Ng, T; + view all (2011) How Forster Resonance Energy Transfer Imaging Improves the Understanding of Protein Interaction Networks in Cancer Biology. CHEMPHYSCHEM , 12 (3) pp. 442-461. 10.1002/cphc.201000866.

Furstenberg, A; Walsh, SB; Howie, A; Jones, G; Unwin, RJ; (2011) Calcineurin-Inhibitor Induced Hypertension, Hyperkalaemia and Metabolic Acidosis Is Caused by Overactivity of the Sodium Chloride Cotransporter. In: AMERICAN JOURNAL OF TRANSPLANTATION. (pp. 406 - 406). WILEY-BLACKWELL

Furuse, J; Okusaka, T; Bridgewater, J; Taketsuna, M; Wasan, H; Koshiji, M; Valle, J; (2011) Lessons from the comparison of two randomized clinical trials using gemcitabine and cisplatin for advanced biliary tract cancer. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY , 80 (1) pp. 31-39. 10.1016/j.critrevonc.2010.10.009.


Gelderblom, H; Jinks, RC; Sydes, M; Bramwell, VHC; van Glabbeke, M; Grimer, RJ; Hogendoorn, PCW; ... Whelan, J; + view all (2011) Survival after recurrent osteosarcoma: Data from 3 European Osteosarcoma Intergroup (EOI) randomized controlled trials. EUROPEAN JOURNAL OF CANCER , 47 (6) pp. 895-902. 10.1016/j.ejca.2010.11.036.

Gillmore, R; Stuart, S; Kirkwood, A; Hameeduddin, A; Woodward, N; Burroughs, AK; Meyer, T; (2011) EASL and mRECIST responses are independent prognostic factors for survival in hepatocellular cancer patients treated with transarterial embolisation. JOURNAL OF HEPATOLOGY , 55 (6) pp. 1309-1316. 10.1016/j.jhep.2011.03.007.

Goldstein, R; Meyer, T; (2011) Role of everolimus in pancreatic neuroendocrine tumors. EXPERT REVIEW OF ANTICANCER THERAPY , 11 (11) pp. 1653-1665. 10.1586/ERA.11.145.

Golubnitschaja, O; Swanton, C; Danesi, R; Costigliola, V; (2011) Promoting predictive, preventive and personalised medicine: European event of global importance. EPMA J , 2 (2) pp. 131-136. 10.1007/s13167-011-0088-8.

Grimmett, C; Bridgewater, J; Steptoe, A; Wardle, J; (2011) Lifestyle and quality of life in colorectal cancer survivors. QUAL LIFE RES , 20 (8) 1237 - 1245. 10.1007/s11136-011-9855-1.

Gunaratnam, M; de la Fuente, M; Hampel, SM; Todd, AK; Reszka, AP; Schaetzlein, A; Neidle, S; (2011) Targeting pancreatic cancer with a G-quadruplex ligand. BIOORGANIC & MEDICINAL CHEMISTRY , 19 (23) pp. 7151-7157. 10.1016/j.bmc.2011.09.055.

Guppy, A; Jamal-Hanjani, M; Pickering, L; (2011) Anticancer effects of metformin and its potential use as a therapeutic agent for breast cancer. FUTURE ONCOLOGY , 7 (6) pp. 727-736. 10.2217/FON.11.49.


Hartley, JA; (2011) The development of pyrrolobenzodiazepines as antitumour agents. EXPERT OPIN INV DRUG , 20 (6) 733 - 744. 10.1517/13543784.2011.573477.

Hartley, JM; Spanswick, VJ; Hartley, JA; (2011) Measurement of DNA damage in individual cells using the Single Cell Gel Electrophoresis (Comet) assay. Methods Mol Biol , 731 pp. 309-320. 10.1007/978-1-61779-080-5_25.

Haylock-Jacobs, S; Comerford, I; Bunting, M; Kara, E; Townley, S; Klingler-Hoffmann, M; Vanhaesebroeck, B; ... McColl, SR; + view all (2011) PI3K delta drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation. JOURNAL OF AUTOIMMUNITY , 36 (3-4) pp. 278-287. 10.1016/j.jaut.2011.02.006.

Hochdoerfer, T; Kuhny, M; Zorn, CN; Hendriks, RW; Vanhaesebroeck, B; Bohnacker, T; Krystal, G; (2011) Activation of the PI3K pathway increases TLR-induced TNF-alpha and IL-6 but reduces IL-1 beta production in mast cells. CELLULAR SIGNALLING , 23 (5) pp. 866-875. 10.1016/j.cellsig.2011.01.012.

Hoorn, EJ; Walsh, SB; McCormick, JA; Furstenberg, A; Yang, CL; Roeschel, T; Paliege, A; ... Ellison, DH; + view all (2011) The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension. NAT MED , 17 (10) 1304 - U339. 10.1038/nm.2497.

Howie, AJ; (2011) Problems with 'focal segmental glomerulosclerosis'. Pediatr Nephrol , 26 (8) pp. 1197-1205. 10.1007/s00467-010-1701-0.


Jamal-Hanjani, M; Pettengell, R; (2011) Pharmacokinetic evaluation of pixantrone for the treatment of non-Hodgkin's lymphoma. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY , 7 (11) pp. 1441-1448. 10.1517/17425255.2011.618834.

Jiao, Y; Lawler, K; Patel, GS; Purushotham, A; Jones, AF; Grigoriadis, A; Tutt, A; ... Teschendorff, AE; + view all (2011) DART: Denoising Algorithm based on Relevance network Topology improves molecular pathway activity inference. BMC BIOINFORMATICS , 12 (ARTN 403) 10.1186/1471-2105-12-403. Gold open access

Johansson, AM; Hill, N; Perisoglou, M; Whelan, J; Karlsson, MO; Standing, JF; (2011) A Population Pharmacokinetic/Pharmacodynamic Model of Methotrexate and Mucositis Scores in Osteosarcoma. THERAPEUTIC DRUG MONITORING , 33 (6) pp. 711-718. 10.1097/FTD.0b013e31823615e1.

Johansson, ÅM; Hill, N; Perisoglou, M; Whelan, J; Karlsson, MO; Standing, JF; (2011) A population pharmacokinetic/pharmacodynamic model of methotrexate and mucositis scores in osteosarcoma. Ther Drug Monit , 33 (6) pp. 711-718. 10.1097/FTD.0b013e31823615e1.

Jose Garcia-Gomez, J; Babiano, R; Lebaron, S; Froment, C; Monsarrat, B; Henry, Y; de la Cruz, J; (2011) Nop6, a component of 90S pre-ribosomal particles, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae. RNA BIOLOGY , 8 (1) pp. 112-124. 10.4161/rna.8.1.14143.

Jose Garcia-Gomez, J; Lebaron, S; Froment, C; Monsarrat, B; Henry, Y; de la Cruz, J; (2011) Dynamics of the Putative RNA Helicase Spb4 during Ribosome Assembly in Saccharomyces cerevisiae. MOLECULAR AND CELLULAR BIOLOGY , 31 (20) pp. 4156-4164. 10.1128/MCB.05436-11.

Juergens, H; Daw, NC; Geoerger, B; Ferrari, S; Villarroel, M; Aerts, I; Whelan, J; ... Gualberto, A; + view all (2011) Preliminary Efficacy of the Anti-Insulin-Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma. JOURNAL OF CLINICAL ONCOLOGY , 29 (34) pp. 4534-4540. 10.1200/JCO.2010.33.0670.


Kato, H; Seto, K; Kobayashi, N; Yoshinaga, K; Meyer, T; Takei, M; (2011) CCK-2/gastrin receptor signaling pathway is significant for gemcitabine-induced gene expression of VEGF in pancreatic carcinoma cells. LIFE SCI , 89 (17-18) 603 - 608. 10.1016/j.lfs.2011.07.019.

Khan, MS; El-Khouly, F; Toumpanakis, C; Meyer, T; Caplin, M; Luong, T; (2011) Ki-67 is a Better Prognostic Marker than Mitotic Count in Neuroendocrine Tumors. In: (Proceedings) 8th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocine Tumor Disease. (pp. p. 31). KARGER

Khan, MS; Tsigani, T; Rashid, M; Rabouhans, JS; Yu, D; Tu, VL; Caplin, M; (2011) Circulating Tumor Cells and EpCAM Expression in Neuroendocrine Tumors. CLIN CANCER RES , 17 (2) 337 - 345. 10.1158/1078-0432.CCR-10-1776.

Kristeleit, RS; baird, R; venugopal, B; wilkins, D; maccormick, F; granata, R; crawford, D; ... de bono, J; + view all (2011) Cardiac effects in a first-in-human (FIH), pharmacokinetic (PK), pharmacodynamic (PD) phase I trial of JNJ-26481585, a second-generation oral hydroxamate histone deacetylase inhibitor (HDACi), in patients with refractory cancer. Molecular Cancer Therapeutics , 10 (11)

Krug, LM; Kindler, H; Calvert, H; Manegold, C; Tsao, AS; Fennell, D; Lubiniecki, GM; ... Baas, P; + view all (2011) VANTAGE 014: Vorinostat (V) in Patients With Advanced Malignant Pleural Mesothelioma (MPM) who Have Failed Prior Pemetrexed and Either Cisplatin or Carboplatin Therapy: A Phase iii, Randomized, Double-Blind, Placebo-Controlled Trial. EUROPEAN JOURNAL OF CANCER , 47 pp. 2-3. 10.1016/S0959-8049(11)70098-3.

Kudsiova, L; Fridrich, B; Ho, J; Mustapa, MFM; Campbell, F; Welser, K; Keppler, M; ... Lawrence, MJ; + view all (2011) Lipopolyplex Ternary Delivery Systems Incorporating C14 Glycerol-Based Lipids. MOL PHARMACEUT , 8 (5) 1831 - 1847. 10.1021/mp2001796.

Kudsiova, L; Ho, J; Fridrich, B; Harvey, R; Keppler, M; Ng, T; Hart, SL; ... Lawrence, MJ; + view all (2011) Lipid chain geometry of C14 glycerol-based lipids: effect on lipoplex structure and transfection. MOL BIOSYST , 7 (2) 422 - 436. 10.1039/c0mb00149j.

Kulkarni, S; Sitaru, C; Jakus, Z; Anderson, KE; Damoulakis, G; Davidson, K; Hirose, M; ... Hawkins, PT; + view all (2011) PI3K beta Plays a Critical Role in Neutrophil Activation by Immune Complexes. SCIENCE SIGNALING , 4 (168) 10.1126/scisignal.2001617.

Kumar, MS; Swanton, C; (2011) KRAS 3 '-UTR variants and stratification of breast-cancer risk. LANCET ONCOLOGY , 12 (4) pp. 318-319. 10.1016/S1470-2045(11)70065-1.


Larkin, J; Swanton, C; Pickering, L; (2011) Optimizing treatment of metastatic renal cell carcinoma by changing mechanism of action. EXPERT REVIEW OF ANTICANCER THERAPY , 11 (4) pp. 639-649. 10.1586/ERA.11.21.

Ledermann, JA; Raja, FA; (2011) Clinical trials and decision-making strategies for optimal treatment of relapsed ovarian cancer. EUROPEAN JOURNAL OF CANCER , 47 S104-S115. 10.1016/S0959-8049(11)70154-X.

Lee, AJX; Endesfelder, D; Rowan, AJ; Walther, A; Birkbak, NJ; Futreal, PA; Downward, J; ... Swanton, C; + view all (2011) Chromosomal Instability Confers Intrinsic Multidrug Resistance. CANCER RESEARCH , 71 (5) pp. 1858-1870. 10.1158/0008-5472.CAN-10-3604.

Lemech, C; Arkenau, HT; (2011) Biomarkers in advanced colorectal cancer: Challenges in translating clinical research into practice. Cancers , 3 (2) pp. 1844-1860. 10.3390/cancers3021844. Gold open access

Lemech, CR; Kristeleit, RS; Arkenau, H; (2011) Novel Oncology drug development strategies in the era of personalised medicine. In: Drug Discovery and Development. InTech

Lemech, CR; Kristeleit, RS; Arkenau, HT; (2011) Novel Oncology Drug Development Strategies in the Era of Personalised Medicine. In: Kapetanovic, IM, (ed.) Drug Discovery and Development - Present and Future.

Leoni, LM; Hartley, JA; (2011) Mechanism of Action: The Unique Pattern of Bendamustine-Induced Cytotoxicity. SEMIN HEMATOL , 48 (2) S12 - S23. 10.1053/j.seminhematol.2011.03.003.

Liccardi, G; Hartley, JA; Hochhauser, D; (2011) EGFR Nuclear Translocation Modulates DNA Repair following Cisplatin and Ionizing Radiation Treatment. CANCER RES , 71 (3) 1103 - 1114. 10.1158/0008-5472.CAN-10-2384. Gold open access

Liccardi, G.; (2011) Nuclear EGFR modulation of DNA repair. Doctoral thesis , UCL (University College London). Green open access

Ligthart, ST; Coumans, FAW; Attard, G; Cassidy, AM; de Bono, JS; Terstappen, LWMM; (2011) Unbiased and Automated Identification of a Circulating Tumour Cell Definition That Associates with Overall Survival. PLOS ONE , 6 (11) 10.1371/journal.pone.0027419.

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This list was generated on Sun Aug 18 04:47:38 2019 BST.