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Number of items: 111.

A

Andrady, C; Sharma, SK; Chester, KA; (2011) Antibody-enzyme fusion proteins for cancer therapy. IMMUNOTHERAPY-UK , 3 (2) 193 - 211. 10.2217/IMT.10.90.

Arkenau, HK; (2011) Capecitabine combined with oxaliplatin (CAPOX) in clinical practice: how significant is peripheral neuropathy? Ann Oncol , 22 (1) pp. 239-240. 10.1093/annonc/mdq676.

Arkenau, HT; Kefford, R; Long, GV; (2011) Targeting BRAF for patients with melanoma. Br J Cancer , 104 (3) pp. 392-398. 10.1038/sj.bjc.6606030.

Arkenau, HT; Nordman, I; Dobbins, T; Ward, R; (2011) Reporting time-to-event endpoints and response rates in 4 decades of randomized controlled trials in advanced colorectal cancer. Cancer , 117 (4) pp. 832-840. 10.1002/cncr.25636.

B

Babu, B; Lee, M; Lee, L; Strobel, R; Brockway, O; Nickols, A; Sjoholm, R; (2011) Acetyl analogs of combretastatin A-4: Synthesis and biological studies. BIOORGAN MED CHEM , 19 (7) 2359 - 2367. 10.1016/j.bmc.2011.02.018.

Babu, B; Liu, Y; Plaunt, A; Riddering, C; Ogilvie, R; Westrate, L; Davis, R; (2011) Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI. BIOCHEM BIOPH RES CO , 404 (3) 848 - 852. 10.1016/j.bbrc.2010.12.073.

Babu, B; Ramos, J; Liu, Y; Chavda, S; Tzou, S; Brockway, O; Sjoholm, R; (2011) Design, synthesis, and DNA binding selectivity and affinity studies of the tetraamide PhIPI and its diamino analog PhIP*I. In: (Proceedings) 242nd National Meeting of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Baraniskin, A; Munding, J; Schulmann, K; Meier, D; Porschen, R; Arkenau, HT; Graeven, U; (2011) Prognostic value of reduced SMAD4 expression in patients with metastatic colorectal cancer under oxaliplatin-containing chemotherapy: a translational study of the AIO colorectal study group. Clin Colorectal Cancer , 10 (1) pp. 24-29. 10.3816/CCC.2011.n.003.

Barton, S; Swanton, C; (2011) Recent developments in treatment stratification for metastatic breast cancer. Drugs , 71 (16) pp. 2099-2113. 10.2165/11594480-000000000-00000.

Beltran, L; Chaussade, C; Vanhaesebroeck, B; Cutillas, PR; (2011) Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity. Proc Natl Acad Sci U S A , 108 (39) pp. 16217-16222. 10.1073/pnas.1107692108.

Birkbak, NJ; Eklund, AC; Li, Q; McClelland, SE; Endesfelder, D; Tan, P; Tan, IB; (2011) Paradoxical relationship between chromosomal instability and survival outcome in cancer. Cancer Res , 71 (10) pp. 3447-3452. 10.1158/0008-5472.CAN-10-3667.

Bridgewater, JA; Stubbs, C; Primrose, JN; National Cancer Research Institute (UK) Upper Gastrointestinal S, ; (2011) BILCAP: A randomized clinical trial evaluating adjuvant chemotherapy with capecitabine compared to expectant treatment alone following curative surgery for biliary tract cancer. J Clin Oncol , 29 (15_suppl) 4125-.

Brough, R; Frankum, JR; Sims, D; Mackay, A; Mendes-Pereira, AM; Bajrami, I; Costa-Cabral, S; (2011) Functional viability profiles of breast cancer. Cancer Discov , 1 (3) pp. 260-273. 10.1158/2159-8290.CD-11-0107.

Brown, NF; Marks, DJ; Smith, PJ; Bloom, SL; (2011) Splenomegaly. Br J Hosp Med (Lond) , 72 (11) M166-M169.

Brucoli, F; Hawkins, RM; James, CH; Wells, G; Jenkins, TC; Ellis, T; Hartley, JA; (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. BIOORG MED CHEM LETT , 21 (12) 3780 - 3783. 10.1016/j.bmcl.2011.04.054.

Brunetto, A; Olmos, D; Arkenau, HT; Tan, D; Yap, T; de Bono, J; Barriuso, J; (2011) Perceptions and referral trends into phase I oncology trials: results of a clinical survey. J Oncol , 2011 861401-. 10.1155/2011/861401.

C

Calvert, H; Azzariti, A; (2011) The clinical development of inhibitors of poly(ADP-ribose) polymerase. ANNALS OF ONCOLOGY , 22 i53 - i59. 10.1093/annonc/mdq667.

Cerone, MA; Burgess, DJ; Naceur-Lombardelli, C; Lord, CJ; Ashworth, A; (2011) High-throughput RNAi screening reveals novel regulators of telomerase. Cancer Res , 71 (9) pp. 3328-3340. 10.1158/0008-5472.CAN-10-2734.

Chavda, S; Liu, Y; Babu, B; Davis, R; Sielaff, A; Ruprich, J; Westrate, L; (2011) Hx, a novel fluorescent, minor groove and sequence specific recognition element: Design, synthesis, and DNA binding properties of p-anisylbenzimidazole imidazole/pyrrole-containing polyamides. In: (Proceedings) 242nd National Meeting of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Chavda, S; Liu, Y; Babu, B; Davis, R; Sielaff, A; Ruprich, J; Westrate, L; (2011) Hx, a Novel Fluorescent, Minor Groove and Sequence Specific Recognition Element: Design, Synthesis, and DNA Binding Properties of p-Anisylbenzimidazole-imidazole/pyrrole-Containing Polyamides. BIOCHEMISTRY-US , 50 (15) 3127 - 3136. 10.1021/bi102028a.

Chew, SK; Rad, R; Futreal, PA; Bradley, A; Liu, P; (2011) Genetic screens using the piggyBac transposon. Methods , 53 (4) pp. 366-371. 10.1016/j.ymeth.2010.12.022.

Coward, J; Kulbe, H; Chakravarty, P; Leader, D; Vassileva, V; Leinster, DA; Thompson, R; (2011) Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer. CLINICAL CANCER RESEARCH , 17 (18) pp. 6083-6096. 10.1158/1078-0432.CCR-11-0945.

Cox, ST; Stephens, HA; Fernando, R; Karasu, A; Harber, M; Howie, AJ; Powis, S; (2011) Major histocompatibility complex class I-related chain A allele mismatching, antibodies, and rejection in renal transplantation. Hum Immunol , 72 (10) pp. 827-834. 10.1016/j.humimm.2011.05.004.

D

De Bono, JS; Logothetis, CJ; Molina, A; Fizazi, K; North, S; Chu, L; Chi, KN; (2011) Abiraterone and Increased Survival in Metastatic Prostate Cancer. NEW ENGLAND JOURNAL OF MEDICINE , 364 (21) pp. 1995-2005.

E

Endesfelder, D; McGranahan, N; Birkbak, NJ; Szallasi, Z; Kschischo, M; Graham, TA; Swanton, C; (2011) A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables. ONCOTARGET , 2 (7) pp. 529-537.

Ertemi, H; Mumtaz, FH; Howie, AJ; Mikhailidis, DP; Thompson, CS; (2011) Effect of Angiotensin II and its Receptor Antagonists on Human Corpus Cavernous Contractility and Oxidative Stress: Modulation of Nitric Oxide Mediated Relaxation. J UROLOGY , 185 (6) 2414 - 2420. 10.1016/j.juro.2011.02.2645.

F

Faelber, K; Posor, Y; Gao, S; Held, M; Roske, Y; Schulze, D; Haucke, V; (2011) Crystal structure of nucleotide-free dynamin. Nature , 477 (7366) pp. 556-560. 10.1038/nature10369.

Feng, H; Hu, B; Liu, KW; Li, Y; Lu, X; Cheng, T; Yiin, JJ; (2011) Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans. J Clin Invest , 121 (12) pp. 4670-4684. 10.1172/JCI58559.

Fenton, TR; Gout, IT; (2011) Functions and regulation of the 70 kDa ribosomal S6 kinases. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY , 43 (1) pp. 47-59. 10.1016/j.bioce1.2010.09.018.

Fisher, R; Larkin, J; Swanton, C; (2011) Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity. EPMA J , 3 (1) 1-. 10.1007/s13167-011-0137-3.

Forster, MD; Dedes, KJ; Sandhu, S; Frentzas, S; Kristeleit, R; Ashworth, A; Poole, CJ; (2011) Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer. Nat Rev Clin Oncol , 8 (5) pp. 302-306. 10.1038/nrclinonc.2011.42.

Furstenberg, A; Walsh, SB; Howie, A; Jones, G; Unwin, RJ; (2011) Calcineurin-Inhibitor Induced Hypertension, Hyperkalaemia and Metabolic Acidosis Is Caused by Overactivity of the Sodium Chloride Cotransporter. In: AMERICAN JOURNAL OF TRANSPLANTATION. (pp. 406 - 406). WILEY-BLACKWELL

Furuse, J; Okusaka, T; Bridgewater, J; Taketsuna, M; Wasan, H; Koshiji, M; Valle, J; (2011) Lessons from the comparison of two randomized clinical trials using gemcitabine and cisplatin for advanced biliary tract cancer. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY , 80 (1) pp. 31-39. 10.1016/j.critrevonc.2010.10.009.

G

García-Gómez, JJ; Babiano, R; Lebaron, S; Froment, C; Monsarrat, B; Henry, Y; de la Cruz, J; (2011) Nop6, a component of 90S pre-ribosomal particles, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae. RNA Biol , 8 (1) pp. 112-124.

García-Gómez, JJ; Lebaron, S; Froment, C; Monsarrat, B; Henry, Y; de la Cruz, J; (2011) Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae. Mol Cell Biol , 31 (20) pp. 4156-4164. 10.1128/MCB.05436-11.

Gillmore, R; Stuart, S; Kirkwood, A; Hameeduddin, A; Woodward, N; Burroughs, AK; Meyer, T; (2011) EASL and mRECIST responses are independent prognostic factors for survival in hepatocellular cancer patients treated with transarterial embolisation. JOURNAL OF HEPATOLOGY , 55 (6) pp. 1309-1316.

Goldstein, R; Meyer, T; (2011) Role of everolimus in pancreatic neuroendocrine tumors. EXPERT REVIEW OF ANTICANCER THERAPY , 11 (11) pp. 1653-1665. 10.1586/ERA.11.145.

Golubnitschaja, O; Swanton, C; Danesi, R; Costigliola, V; (2011) Promoting predictive, preventive and personalised medicine: European event of global importance. EPMA J , 2 (2) pp. 131-136. 10.1007/s13167-011-0088-8.

Grimmett, C; Bridgewater, J; Steptoe, A; Wardle, J; (2011) Lifestyle and quality of life in colorectal cancer survivors. QUAL LIFE RES , 20 (8) 1237 - 1245. 10.1007/s11136-011-9855-1.

Gunaratnam, M; de la Fuente, M; Hampel, SM; Todd, AK; Reszka, AP; Schätzlein, A; Neidle, S; (2011) Targeting pancreatic cancer with a G-quadruplex ligand. Bioorg Med Chem , 19 (23) pp. 7151-7157. 10.1016/j.bmc.2011.09.055.

Guppy, A; Jamal-Hanjani, M; Pickering, L; (2011) Anticancer effects of metformin and its potential use as a therapeutic agent for breast cancer. Future Oncol , 7 (6) pp. 727-736. 10.2217/fon.11.49.

H

Hartley, JA; (2011) The development of pyrrolobenzodiazepines as antitumour agents. EXPERT OPIN INV DRUG , 20 (6) 733 - 744. 10.1517/13543784.2011.573477.

Hartley, JM; Spanswick, VJ; Hartley, JA; (2011) Measurement of DNA damage in individual cells using the Single Cell Gel Electrophoresis (Comet) assay. Methods Mol Biol , 731 pp. 309-320. 10.1007/978-1-61779-080-5_25.

Haylock-Jacobs, S; Comerford, I; Bunting, M; Kara, E; Townley, S; Klingler-Hoffmann, M; Vanhaesebroeck, B; (2011) PI3Kδ drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation. J Autoimmun , 36 (3-4) pp. 278-287. 10.1016/j.jaut.2011.02.006.

Hochdörfer, T; Kuhny, M; Zorn, CN; Hendriks, RW; Vanhaesebroeck, B; Bohnacker, T; Krystal, G; (2011) Activation of the PI3K pathway increases TLR-induced TNF-α and IL-6 but reduces IL-1β production in mast cells. Cell Signal , 23 (5) pp. 866-875. 10.1016/j.cellsig.2011.01.012.

Holme, H; Nanduri, V; (2011) Superior vena cava obstruction: dangers of a missed diagnosis. J Paediatr Child Health , 47 (3) pp. 150-151. 10.1111/j.1440-1754.2010.01741.x.

Hoorn, EJ; Walsh, SB; McCormick, JA; Furstenberg, A; Yang, CL; Roeschel, T; Paliege, A; (2011) The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension. NAT MED , 17 (10) 1304 - U339. 10.1038/nm.2497.

Howie, AJ; (2011) Problems with 'focal segmental glomerulosclerosis'. Pediatr Nephrol , 26 (8) pp. 1197-1205. 10.1007/s00467-010-1701-0.

J

Jamal-Hanjani, M; Pettengell, R; (2011) Pharmacokinetic evaluation of pixantrone for the treatment of non-Hodgkin's lymphoma. Expert Opin Drug Metab Toxicol , 7 (11) pp. 1441-1448. 10.1517/17425255.2011.618834.

Jiao, Y; Lawler, K; Patel, GS; Purushotham, A; Jones, AF; Grigoriadis, A; Tutt, A; (2011) DART: Denoising Algorithm based on Relevance network Topology improves molecular pathway activity inference. BMC BIOINFORMATICS , 12 (ARTN 403) 10.1186/1471-2105-12-403. Gold open access

Johansson, AM; Hill, N; Perisoglou, M; Whelan, J; Karlsson, MO; Standing, JF; (2011) A population pharmacokinetic/pharmacodynamic model of methotrexate and mucositis scores in osteosarcoma. Therapeutic Drug Monitoring , 33 (6) pp. 711-718. 10.1097/FTD.0b013e31823615e1.

Juergens, H; Daw, NC; Geoerger, B; Ferrari, S; Villarroel, M; Aerts, I; Whelan, J; (2011) Preliminary Efficacy of the Anti-Insulin-Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma. JOURNAL OF CLINICAL ONCOLOGY , 29 (34) pp. 4534-4540. 10.1200/JCO.2010.33.0670.

K

Kato, H; Seto, K; Kobayashi, N; Yoshinaga, K; Meyer, T; Takei, M; (2011) CCK-2/gastrin receptor signaling pathway is significant for gemcitabine-induced gene expression of VEGF in pancreatic carcinoma cells. LIFE SCI , 89 (17-18) 603 - 608. 10.1016/j.lfs.2011.07.019.

Khan, MS; Tsigani, T; Rashid, M; Rabouhans, JS; Yu, D; Tu, VL; Caplin, M; (2011) Circulating Tumor Cells and EpCAM Expression in Neuroendocrine Tumors. CLIN CANCER RES , 17 (2) 337 - 345. 10.1158/1078-0432.CCR-10-1776.

Kudsiova, L; Fridrich, B; Ho, J; Mustapa, MFM; Campbell, F; Welser, K; Keppler, M; (2011) Lipopolyplex Ternary Delivery Systems Incorporating C14 Glycerol-Based Lipids. MOL PHARMACEUT , 8 (5) 1831 - 1847. 10.1021/mp2001796.

Kudsiova, L; Ho, J; Fridrich, B; Harvey, R; Keppler, M; Ng, T; Hart, SL; (2011) Lipid chain geometry of C14 glycerol-based lipids: effect on lipoplex structure and transfection. MOL BIOSYST , 7 (2) 422 - 436. 10.1039/c0mb00149j.

Kulkarni, S; Sitaru, C; Jakus, Z; Anderson, KE; Damoulakis, G; Davidson, K; Hirose, M; (2011) PI3Kβ plays a critical role in neutrophil activation by immune complexes. Sci Signal , 4 (168) ra23-. 10.1126/scisignal.2001617.

Kumar, MS; Swanton, C; (2011) KRAS 3'-UTR variants and stratification of breast-cancer risk. Lancet Oncol , 12 (4) pp. 318-319. 10.1016/S1470-2045(11)70065-1.

L

Larkin, J; Swanton, C; Pickering, L; (2011) Optimizing treatment of metastatic renal cell carcinoma by changing mechanism of action. Expert Rev Anticancer Ther , 11 (4) pp. 639-649. 10.1586/era.11.21.

Ledermann, JA; Raja, FA; (2011) Clinical trials and decision-making strategies for optimal treatment of relapsed ovarian cancer. EUROPEAN JOURNAL OF CANCER , 47 S104-S115.

Lee, AJ; Endesfelder, D; Rowan, AJ; Walther, A; Birkbak, NJ; Futreal, PA; Downward, J; (2011) Chromosomal instability confers intrinsic multidrug resistance. Cancer Res , 71 (5) pp. 1858-1870. 10.1158/0008-5472.CAN-10-3604.

Leoni, LM; Hartley, JA; (2011) Mechanism of Action: The Unique Pattern of Bendamustine-Induced Cytotoxicity. SEMIN HEMATOL , 48 (2) S12 - S23. 10.1053/j.seminhematol.2011.03.003.

Liccardi, G; Hartley, JA; Hochhauser, D; (2011) EGFR Nuclear Translocation Modulates DNA Repair following Cisplatin and Ionizing Radiation Treatment. CANCER RES , 71 (3) 1103 - 1114. 10.1158/0008-5472.CAN-10-2384. Gold open access

Liccardi, G.; (2011) Nuclear EGFR modulation of DNA repair. Doctoral thesis, UCL (University College London). Green open access
file

Lin, S; Kiakos, K; Lee, M; Hochhauser, D; Hartley, JA; (2011) Targeting the Mlul cell cycle box (MCB) sequence 5 '-ACGCGT-3 ' in the human Dbf4 promoter using the rationally designed polyamide formamido-imidazole-pyrrole-imidazole (f-IPI). CANCER RESEARCH , 71 10.1158/1538-7445.AM2011-665.

Liu, H; Wang, W; Chew, SK; Lee, SC; Li, J; Vassiliou, GS; Green, T; (2011) Stella-Cre mice are highly efficient Cre deleters. Genesis , 49 (8) pp. 689-695. 10.1002/dvg.20741.

Lolkema, MP; Arkenau, HT; Harrington, K; Roxburgh, P; Morrison, R; Roulstone, V; Twigger, K; (2011) A phase I study of the combination of intravenous reovirus type 3 Dearing and gemcitabine in patients with advanced cancer. Clin Cancer Res , 17 (3) pp. 581-588. 10.1158/1078-0432.CCR-10-2159.

Lowe, H.L.; (2011) Design, construction and evaluation of a humanised ADEPT system. Doctoral thesis, UCL (University College London).

M

Mahadevan, D; Plummer, R; Squires, MS; Rensvold, D; Kurtin, S; Pretzinger, C; Dragovich, T; (2011) A phase I pharmacokinetic and pharmacodynamic study of AT7519, a cyclin-dependent kinase inhibitor in patients with refractory solid tumors. ANN ONCOL , 22 (9) 2137 - 2143. 10.1093/annonc/mdq734.

Mansur, A; Little, MA; Oh, WC; Jacques, S; Nightingale, P; Howie, AJ; Savage, COS; (2011) Immune Profile and Epstein-Barr Virus Infection in Acute Interstitial Nephritis: An Immunohistochemical Study in 78 Patients. NEPHRON CLINICAL PRACTICE , 119 (4) C293-C300. 10.1159/000329671.

Marsh, D; Suchak, K; Moutasim, KA; Vallath, S; Hopper, C; Jerjes, W; Upile, T; (2011) Stromal features are predictive of disease mortality in oral cancer patients. J PATHOL , 223 (4) 470 - 481. 10.1002/path.2830.

Maughan, T; Wilson, RH; Williams, GT; Seymour, MT; Richman, S; Quirke, P; Pope, M; (2011) Developing a biomarker-stratified trial design in advanced colorectal cancer: The MRC FOCUS 3 feasibility study. J Clin Oncol , 29 (15_suppl) TPS165-.

Maughan, TS; Adams, RA; Smith, CG; Meade, AM; Seymour, MT; Wilson, RH; Idziaszczyk, S; (2011) Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet , 377 (9783) pp. 2103-2114. 10.1016/S0140-6736(11)60613-2.

McCaughan, F; Pipinikas, CP; Janes, SM; George, PJ; Rabbitts, PH; Dear, PH; (2011) Genomic evidence of pre-invasive clonal expansion, dispersal and progression in bronchial dysplasia. J PATHOL , 224 (2) 153 - 159. 10.1002/path.2887.

Melichar, B; Casado, E; Bridgewater, J; Bennouna, J; Campone, M; Vitek, P; Delord, J-P; (2011) Clinical activity of patupilone in patients with pretreated advanced/metastatic colon cancer: results of a phase I dose escalation trial. BRITISH JOURNAL OF CANCER , 105 (11) pp. 1646-1653. 10.1038/bjc.2011.438.

Middleton, GW; Gwyther, SJ; Brown, SR; Maughan, T; Olivier, C; Richman, S; Maisey, NR; (2011) Biomodulation of irinotecan using ciclosporin: Results of PICCOLO, a randomized controlled trial in advanced colorectal cancer (aCRC). J Clin Oncol , 29 (15_suppl) 3566-.

O

Osawa, T; Davies, D; Hartley, JA; (2011) Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells. CELL DEATH DIS , 2 , Article e187. 10.1038/cddis.2011.70. Gold open access

P

Pacey, S; Wilson, RH; Walton, M; Eatock, MM; Hardcastle, A; Zetterlund, A; Arkenau, HT; (2011) A phase I study of the heat shock protein 90 inhibitor alvespimycin (17-DMAG) given intravenously to patients with advanced solid tumors. Clin Cancer Res , 17 (6) pp. 1561-1570. 10.1158/1078-0432.CCR-10-1927.

Plummer, R; Wilson, RH; Calvert, H; Boddy, AV; Griffin, M; Sludden, J; Tilby, MJ; (2011) A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours. BRIT J CANCER , 104 (4) 593 - 598. 10.1038/bjc.2011.6.

Pors, K; Loadman, PM; Shnyder, SD; Sutherland, M; Sheldrake, HM; Guino, M; Kiakos, K; (2011) Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity. CHEM COMMUN , 47 (44) 12062 - 12064. 10.1039/c1cc15638a.

Puzanov, I; Lee, W; Chen, AP; Calcutt, MW; Hachey, DL; Vermeulen, WL; Spanswick, VJ; (2011) Phase I Pharmacokinetic and Pharmacodynamic Study of SJG-136, a Novel DNA Sequence Selective Minor Groove Cross-linking Agent, in Advanced Solid Tumors. CLIN CANCER RES , 17 (11) 3794 - 3802. 10.1158/1078-0432.CCR-10-2056.

R

Raja, FA; Griffin, CL; Qian, W; Hirte, H; Parmar, MK; Swart, AM; Ledermann, JA; (2011) Initial toxicity assessment of ICON6: a randomised trial of cediranib plus chemotherapy in platinum-sensitive relapsed ovarian cancer. BRIT J CANCER , 105 (7) 884 - 889. 10.1038/bjc.2011.334.

Reid, JM; Buhrow, SA; Kuffel, MJ; Jia, L; Spanswick, VJ; Hartley, JA; Thurston, DE; (2011) Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats. CANCER CHEMOTH PHARM , 68 (3) 777 - 786. 10.1007/s00280-010-1517-4.

Roylance, R; Endesfelder, D; Gorman, P; Burrell, RA; Sander, J; Tomlinson, I; Hanby, AM; (2011) Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer. Cancer Epidemiol Biomarkers Prev , 20 (10) pp. 2183-2194. 10.1158/1055-9965.EPI-11-0343.

Rustin, G; Reed, N; Jayson, GC; Ledermann, JA; Adams, M; Perren, T; Poole, C; (2011) A phase II trial evaluating two schedules of sagopilone (ZK-EPO), a novel epothilone, in patients with platinum-resistant ovarian cancer. ANN ONCOL , 22 (11) 2411 - 2416. 10.1093/annonc/mdq780.

S

Salazar, R; Plummer, R; Oaknin, A; Robinson, A; Pardo, B; Soto-Matos, A; Yovine, A; (2011) Phase I study of weekly plitidepsin as 1-hour infusion combined with carboplatin in patients with advanced solid tumors or lymphomas. INVEST NEW DRUG , 29 (6) 1406 - 1413. 10.1007/s10637-010-9488-1.

Saravanan, K; Barlow, HC; Barton, M; Calvert, AH; Golding, BT; Newell, DR; Northen, JS; (2011) Nucleoside Transport Inhibitors: Structure-Activity Relationships for Pyrimido[5,4-d]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of alpha(1)-Acid Glycoprotein. J MED CHEM , 54 (6) 1847 - 1859. 10.1021/jm101493z.

Short, SC; Giampieri, S; Worku, M; Alcaide-German, M; Sioftanos, G; Bourne, S; Lio, KI; (2011) Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+tumor-derived cells. NEURO-ONCOLOGY , 13 (5) pp. 487-499. 10.1093/neuonc/nor010.

Siddiqui, GK; Maclean, AB; Elmasry, K; Fong, AWT; Morris, RW; Rashid, M; Begent, RHJ; (2011) Immunohistochemical expression of VEGF predicts response to platinum based chemotherapy in patients with epithelial ovarian cancer. ANGIOGENESIS , 14 (2) 155 - 161. 10.1007/s10456-010-9199-4.

Sims, D; Mendes-Pereira, AM; Frankum, J; Burgess, D; Cerone, MA; Lombardelli, C; Mitsopoulos, C; (2011) High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing. Genome Biol , 12 (10) R104-. 10.1186/gb-2011-12-10-r104.

Sivabalasingham, S; Fersht, N; D'Souza, D; Rosenberg, I; Stacey, C; Davies, P; Guerro-Urbano, T; (2011) Preliminary Results from a Phase I/II Study of Intensity Modulated Radiotherapy in the Treatment of Meningiomas. CLIN ONCOL-UK , 23 (3) S53 - S53.

Smith, SW; Eardley, KS; Croft, AP; Nwosu, J; Howie, AJ; Cockwell, P; Isacke, CM; (2011) CD248(+) stromal cells are associated with progressive chronic kidney disease. KIDNEY INTERNATIONAL , 80 (2) pp. 200-208. 10.1038/ki.2011.103.

Spencer, J; Amin, J; Coxhead, P; McGeehan, J; Richards, CJ; Tizzard, GJ; Coles, SJ; (2011) Size Does Matter. Sterically Demanding Metallocene-Substituted 3-Methylidene-Oxindoles Exhibit Poor Kinase Inhibitory Action. ORGANOMETALLICS , 30 (11) 3177 - 3181. 10.1021/om200278j.

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This list was generated on Sun Mar 26 03:58:54 2017 BST.